Hub : Genes

VDAC2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0710	0.0260	3.3e-04	0.091	NA	0.057	NA	0.072	7.0e-08	NA	1.8e-05	NA	1.6e-06
2	GTEx	Adipose Visceral Omentum	0.1210	0.0510	2.3e-03	0.014	NA	0.017	NA	0.019	5.9e-02	NA	4.5e-02	NA	3.6e-02
3	GTEx	Artery Tibial	0.0536	0.0246	7.2e-03	0.002	NA	0.002	NA	-0.003	2.0e-01	NA	2.0e-01	NA	6.3e-01
4	GTEx	Cells Transformed fibroblasts	0.0750	0.0320	3.3e-03	0.031	NA	0.030	NA	0.031	2.1e-03	NA	2.3e-03	NA	2.0e-03
5	GTEx	Muscle Skeletal	0.0753	0.0278	3.5e-04	0.043	NA	0.055	NA	0.037	4.6e-05	NA	3.9e-06	NA	1.5e-04
6	GTEx	Nerve Tibial	0.0654	0.0278	3.3e-03	0.073	NA	0.058	NA	0.074	7.0e-06	NA	5.8e-05	NA	5.9e-06
7	GTEx	Testis	0.2690	0.0630	2.8e-08	0.081	NA	0.239	NA	0.099	1.9e-04	NA	5.5e-11	NA	3.6e-05
8	GTEx	Whole Blood	0.0470	0.0220	5.2e-03	0.053	NA	0.047	NA	0.050	1.2e-05	NA	3.7e-05	NA	2.1e-05
9	METSIM	Adipose	0.0994	0.0291	8.0e-12	0.112	0.082	0.088	0.086	0.116	2.2e-16	2.7e-12	3.7e-13	8.6e-13	6.7e-17
10	YFS	Blood	0.0113	0.0061	1.2e-02	0.010	0.005	0.003	0.005	0.009	2.6e-04	5.7e-03	4.0e-02	8.0e-03	5.9e-04
11	TCGA	Breast Invasive Carcinoma	0.0362	0.0178	6.1e-05	0.013	0.021	0.023	NA	0.019	9.0e-04	2.4e-05	1.1e-05	NA	6.7e-05
12	TCGA	Brain Lower Grade Glioma	0.0210	0.0121	2.5e-03	0.016	0.020	0.012	NA	0.012	5.7e-03	2.4e-03	1.4e-02	NA	1.6e-02
13	TCGA	Liver Hepatocellular Carcinoma	0.1180	0.0710	7.1e-03	0.032	0.023	0.002	NA	0.019	1.1e-02	3.0e-02	2.4e-01	NA	4.3e-02
14	TCGA	Lung Squamous Cell Carcinoma	0.0506	0.0340	1.8e-03	0.037	0.022	0.025	NA	-0.002	4.2e-05	1.4e-03	6.6e-04	NA	9.0e-01
15	TCGA	Prostate Adenocarcinoma	0.0423	0.0271	7.6e-03	0.003	0.011	0.018	NA	0.006	1.5e-01	2.0e-02	5.0e-03	NA	7.6e-02
16	TCGA	Thyroid Carcinoma	0.0520	0.0340	3.2e-03	0.015	0.002	0.012	NA	0.012	1.1e-02	1.7e-01	2.2e-02	NA	2.2e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	1.0	1.6	3.5	-1.4	-1.9	-1.7	-1.8	-1.3	-0.8	-0.7	-1.0	-1.3	1.4	-1.2	-1.4	-0.8	-1.3	0.0	-0.7
Bipolar Disorder or Schizophrenia	0.2	0.4	1.6	0.1	-1.2	-0.3	-0.3	-0.0	1.2	0.1	0.2	-0.1	-0.1	0.7	-0.1	0.3	0.2	1.3	0.8
Depressed Affect (Nagel 2018)	1.1	2.3	8.2	-1.4	-1.1	-2.4	-1.5	-0.6	-1.7	-1.7	-1.1	-1.3	1.2	-2.0	-1.6	-2.9	-0.0	-0.4	-0.4
Depression (Nagel 2018)	0.5	0.7	2.4	0.1	-1.0	-1.5	-0.5	0.8	-1.6	-0.6	0.5	0.2	-0.4	-0.1	-0.9	-1.2	0.6	-0.6	0.7
Intelligence (Savage-Jansen 2018)	0.8	2.4	5.6	-1.6	0.9	-1.6	-2.2	-2.2	-1.0	-0.7	-2.1	-2.3	1.5	-1.1	-2.4	-1.0	-1.3	0.1	-0.1
Neuroticism (Nagel 2018)	1.1	2.7	6.5	-1.9	-1.2	-2.6	-1.5	-0.8	-1.8	-1.7	-1.5	-1.6	1.7	-1.8	-1.7	-2.5	-0.8	-1.0	-1.0
Schizophrenia (2018)	0.8	1.6	4.8	1.3	-0.1	0.9	1.1	1.0	2.2	0.7	1.1	1.0	-1.2	1.8	1.0	1.1	1.3	1.6	1.6
Schizophrenia vs Biploar Disorder	1.1	1.4	6.1	0.6	2.0	1.8	1.3	1.0	2.5	1.4	0.3	0.4	-0.4	0.3	1.4	0.5	1.0	0.6	0.3
Worry (Nagel 2018)	0.3	0.7	2.0	-0.8	-1.2	-1.4	-0.4	0.2	-1.4	-0.4	-0.6	-0.4	0.6	-0.3	-0.7	-0.5	-0.9	-1.1	-0.9
Alzheimer’s Disease (in mother)	1.0	1.2	2.9	-1.1	-1.2	-1.7	-1.6	-0.4	-1.1	-1.1	-1.4	-1.4	1.0	-0.8	-1.3	-0.8	-0.8	-0.1	-0.1
Alzheimer’s Disease (in father)	1.4	1.5	3.8	0.9	-0.8	1.0	1.8	0.9	1.1	1.6	0.7	1.0	-0.7	1.7	1.9	1.9	0.3	1.5	0.2
Alzheimer’s Disease (including proxy)	0.4	0.5	1.8	0.4	-1.4	-0.1	0.7	0.7	0.3	0.5	-0.2	0.2	-0.3	1.2	0.8	0.7	0.4	1.3	0.7
Crohns Disease (2017)	0.3	0.6	4.1	0.4	-0.7	0.5	0.5	1.2	-0.4	2.0	0.6	0.4	-0.5	0.7	0.1	-0.2	0.7	0.6	0.8
Irritable Bowel Disease (IBD)	0.3	0.6	2.3	0.7	-1.0	0.2	0.5	1.1	-0.1	1.5	0.7	0.6	-0.8	1.2	0.3	0.1	0.6	0.9	0.8
Ulcerative Colitis (UC)	0.2	0.4	1.5	0.8	-0.4	0.2	0.5	0.6	0.3	0.6	0.6	0.7	-0.8	1.2	0.3	0.5	0.4	0.3	0.6
Major Depression (MDD)	3.9	4.8	7.8	-2.6	-0.6	-2.7	-2.4	-2.1	-2.8	-1.6	-2.4	-2.5	2.5	-2.3	-2.3	-1.9	-1.9	-1.5	-1.8
Reaction Time	1.3	2.4	4.8	1.1	2.1	1.9	2.1	1.5	1.3	2.0	0.9	1.4	-1.0	0.3	2.1	1.0	2.2	1.3	1.2
Verbal and Numeric Reasoning (VNR)	1.3	3.2	8.0	-1.7	0.7	-2.4	-2.7	-2.0	-1.4	-1.5	-2.0	-2.3	1.6	-1.2	-2.8	-0.9	-2.0	-0.5	-0.5
Breast Cancer	0.6	1.4	4.0	-1.3	1.9	-1.0	-0.4	-1.2	-0.2	-0.4	-1.1	-0.8	1.4	-1.4	-0.2	-0.1	-1.5	-1.5	-2.0
Ovarian Cancer	0.9	1.1	2.8	1.3	-1.1	0.4	1.1	1.1	-0.9	0.5	1.7	1.5	-1.5	1.0	0.8	-0.3	1.4	-0.3	0.6
Prostate Cancer	2.1	2.9	6.4	2.0	1.0	1.3	1.3	2.3	1.3	1.3	1.6	1.5	-2.1	2.2	1.0	0.3	2.4	1.6	2.5
Age at First Birth	1.3	1.8	4.3	1.5	1.2	1.7	1.1	1.4	1.0	2.1	1.5	1.6	-1.5	1.1	1.4	1.6	1.0	0.4	0.8
Bipolar Disorder (2011)	0.4	0.4	1.7	0.8	-0.0	-0.3	-0.3	0.1	0.6	-0.4	0.9	0.5	-0.8	0.9	-0.5	0.1	0.5	0.9	1.3
Body Mass Index (BMI) (2010)	0.8	1.1	4.1	-1.0	0.0	-1.4	-0.9	-0.2	-0.3	-1.3	-1.1	-1.2	1.0	-1.0	-1.4	-2.0	-0.6	-1.1	-0.5
Coronary Artery Disease (CAD)	2.1	2.5	4.6	1.6	0.7	1.8	1.4	1.8	1.9	1.9	1.5	1.4	-1.5	2.2	1.6	1.9	1.3	1.1	1.3
Crohns Disease (2012)	0.2	0.3	1.1	0.1	-0.6	0.5	0.8	0.7	0.1	1.1	0.5	0.4	-0.2	0.8	0.5	0.2	0.5	0.4	0.6
Mean Putamen Volume	0.8	0.9	3.0	-1.2	0.6	-0.9	-0.2	-0.8	-0.8	-0.4	-1.0	-0.7	1.3	-0.6	-0.0	0.5	-1.7	-1.1	-1.7
Fasting Glucose	0.3	0.3	1.1	-0.7	-1.1	-0.2	-0.2	0.4	-0.1	-0.2	-1.0	-0.9	0.7	-0.2	-0.0	-0.4	0.2	0.9	0.2
HbA1C	1.0	1.1	3.0	0.5	0.8	1.2	0.6	1.3	0.9	1.0	1.1	0.5	-0.5	1.1	0.7	0.4	1.7	1.5	1.7
HDL Cholesterol	4.2	7.0	12.7	2.9	1.5	2.5	2.6	2.9	1.9	2.8	2.9	2.8	-2.9	3.6	2.4	2.5	2.5	2.2	2.7
LDL Cholesterol	0.3	0.5	1.2	-0.8	0.3	-0.4	-0.9	-0.7	0.3	-0.7	-0.6	-1.0	0.8	-0.1	-1.1	-0.8	-0.8	-0.5	-0.2
Lupus	0.7	1.0	4.0	-0.7	-0.1	-1.4	-0.6	-0.8	0.5	-1.5	-0.3	-0.6	0.8	1.2	-1.0	1.4	-2.0	-0.8	-0.6
Neuroticism (2016)	1.6	2.3	4.4	-1.9	0.2	-1.8	-1.6	-1.0	-1.2	-1.6	-1.6	-1.6	1.8	-2.1	-1.6	-2.0	-0.9	-1.1	-1.1
Primary Biliary Cirrhosis	0.7	1.0	2.4	1.1	-1.3	1.1	1.1	1.3	1.5	-0.1	1.0	1.0	-1.0	1.3	1.1	0.4	0.6	0.6	0.2
Rheumatoid Arthritis	0.1	0.1	0.4	-0.1	0.4	-0.0	0.3	-0.2	0.4	-0.1	-0.2	0.1	0.2	0.4	0.4	0.7	-0.5	-0.1	-0.2
Schizophrenia (2014)	0.6	1.2	7.5	0.9	-0.4	0.7	0.7	0.9	2.7	0.3	0.8	0.6	-0.8	1.6	0.6	1.3	0.6	1.4	1.2
Triglycerides	1.8	3.0	5.1	-1.7	1.2	-1.4	-1.8	-1.7	-0.9	-2.3	-1.9	-2.1	1.7	-1.7	-2.2	-2.0	-1.5	-1.9	-1.1
Type 2 Diabetes (T2D) (2012)	2.0	2.3	6.4	-1.3	-0.8	-1.6	-0.8	-1.1	-1.4	-2.0	-1.1	-1.0	1.3	-0.7	-1.4	-1.2	-2.2	-2.5	-2.0
Ulcerative Colitis	0.3	0.5	1.7	0.7	0.2	0.1	0.6	0.4	0.9	0.5	0.6	0.7	-0.6	1.3	0.6	1.3	0.1	0.8	0.6
Blood Eosinophil Count	0.1	0.9	6.0	-0.6	2.4	-1.0	-0.8	-1.6	0.2	-0.7	-0.3	-0.6	0.6	-0.7	-1.0	-0.4	-1.0	-0.5	-0.6
Blood Platelet Count	0.7	8.4	24.6	-3.3	5.0	-1.4	-1.6	-3.4	0.7	-1.4	-3.5	-3.1	3.4	-3.7	-1.9	-2.3	-2.1	-3.5	-2.9
Blood Red Count	0.1	0.7	1.3	0.8	0.9	1.1	1.1	0.6	0.4	-0.5	0.8	0.9	-0.8	0.9	1.0	1.1	0.8	0.4	0.7
Blood White Count	0.1	0.4	5.1	-0.2	2.3	-0.3	0.6	-0.1	0.5	-0.5	-0.0	0.2	0.1	0.2	0.5	0.6	0.0	-0.4	-0.2
Heel T-Score	0.3	2.3	4.4	1.4	2.1	1.5	2.0	1.5	0.5	1.3	1.6	2.0	-1.4	1.7	1.9	2.1	0.6	0.4	0.7
BMI	2.3	13.6	25.8	-4.8	0.2	-4.0	-3.5	-3.6	-1.2	-2.4	-5.1	-5.0	4.9	-3.9	-3.7	-3.7	-3.5	-2.2	-3.1
Height	0.2	3.9	29.7	-0.9	-2.4	-3.1	-1.3	1.0	-5.5	-1.1	-0.3	-0.4	0.3	-0.7	-1.8	-2.4	-0.3	-1.8	0.2
Waist Hip Ratio (WHR)	0.1	0.4	1.1	0.6	-1.1	0.7	0.3	-0.7	0.1	0.3	0.9	0.7	-0.6	0.4	0.5	1.1	0.0	0.5	-0.1
Systolic Blood Pressure	1.5	7.4	24.4	-2.2	-1.2	-3.3	-3.4	-3.1	-4.9	-2.7	-1.8	-2.3	1.9	-3.1	-3.4	-3.0	-1.8	-1.2	-0.8
Smoking Status	0.7	1.8	7.3	-0.8	-2.7	-1.6	-1.0	-0.6	-2.2	-1.8	-0.6	-0.7	0.5	-0.8	-1.5	-1.9	-0.4	-0.9	-0.5
Allergy or Eczema	0.4	1.2	2.1	-1.0	-1.2	-1.3	-1.2	-1.3	-0.1	-1.0	-1.2	-1.3	1.1	-0.5	-1.5	-1.1	-1.4	-0.3	-0.7
Cardiovascular Disease	0.7	2.4	7.1	-1.6	0.4	-1.8	-1.5	-1.2	-2.7	-1.0	-1.4	-1.4	1.3	-2.2	-1.6	-2.0	-0.6	-1.5	-0.9
Hypothyroidism (self reported)	2.9	6.7	14.1	-2.4	-1.5	-3.6	-2.9	-1.9	-2.8	-3.2	-2.5	-2.8	2.2	-1.9	-3.7	-3.8	-1.8	-1.6	-0.7
Respiratory disease	4.3	9.5	14.3	-3.4	-1.5	-3.2	-3.5	-3.2	-1.7	-3.0	-3.1	-3.3	3.4	-3.8	-2.8	-3.1	-3.2	-2.7	-3.5
Type 2 Diabetes (T2D) (2018)	2.1	3.9	8.5	-2.3	0.7	-2.0	-1.8	-1.7	-1.1	-1.9	-2.0	-2.1	2.3	-2.9	-1.4	-2.2	-1.4	-2.0	-2.3
Lung FEV1/FVC ratio	0.1	0.5	3.1	0.7	0.8	0.3	0.5	-0.2	-1.8	0.2	0.7	0.8	-0.8	1.1	-0.2	0.1	0.0	-0.7	0.7
Lung FVC	2.2	11.3	23.3	-4.1	-0.2	-3.0	-2.4	-3.5	-2.4	-3.3	-4.2	-3.7	4.1	-2.4	-3.0	-3.0	-3.6	-4.8	-3.5
Neuroticism	0.3	0.7	4.0	-0.4	-1.5	-1.0	-0.1	0.8	-1.6	-0.3	-0.1	-0.1	0.1	-0.7	-0.3	-2.0	0.8	-0.0	0.0
Chronotype (morning person)	0.4	0.8	2.1	-1.1	0.4	-0.1	-0.3	-1.0	-0.4	-0.5	-1.4	-0.9	1.1	-1.0	-0.4	-0.3	-1.1	-1.3	-1.4
Hair Pigment	0.1	2.6	8.4	-1.5	-2.9	-2.6	-1.4	-0.8	-1.8	-2.0	-1.1	-1.2	1.4	-1.5	-1.1	-1.5	-1.4	-0.6	-1.1
Tanning	0.0	0.2	1.2	0.0	1.1	0.3	0.0	-0.4	-0.1	0.4	-0.5	-0.0	-0.0	-0.3	-0.1	-0.1	-0.4	-0.7	-0.4
Hand grip strength (left)	0.1	0.4	2.8	0.4	-1.7	-0.5	-0.3	0.1	-1.0	-0.6	0.5	0.3	-0.5	0.4	-0.4	-0.2	-0.4	-0.5	0.0
Number of treatments/medications taken	3.1	5.6	9.6	-2.9	-1.2	-2.7	-2.4	-2.0	-1.9	-3.0	-3.1	-2.9	2.8	-2.1	-2.6	-2.0	-2.0	-1.5	-1.5
Average weekly spirits intake	1.4	1.8	5.6	-1.3	-2.4	-1.4	-1.3	-0.9	-1.9	-1.0	-1.2	-1.5	1.2	-1.1	-1.6	-1.7	-0.3	0.4	0.2
Sensitivity / hurt feelings	0.8	1.4	3.1	-1.5	-0.3	-1.2	-0.4	-0.9	-1.0	-1.2	-1.2	-1.0	1.5	-1.5	-0.6	-1.2	-1.1	-1.4	-1.8
Frequency of depressed mood in last 2 weeks	0.6	0.9	3.1	0.9	-0.2	-0.2	0.7	1.8	-0.3	0.3	1.0	0.9	-1.0	1.3	0.3	0.3	1.1	0.8	1.5
Hearing difficulty/problems: Yes	1.6	2.4	7.5	0.9	0.9	1.2	1.8	2.1	1.4	2.7	0.6	0.9	-0.9	2.2	1.4	1.9	0.9	1.6	1.6
Relative age of first facial hair	8.0	16.4	25.5	4.4	0.1	4.4	4.0	4.8	2.4	4.9	4.5	4.4	-4.5	3.2	4.1	2.5	5.0	4.4	4.2
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	2.2	-1.1	-0.9	-1.3	-1.4	-1.1	-1.2	-0.9	-1.1	-1.4	1.0	-0.8	-1.5	-1.2	-0.8	0.0	-0.2
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.3	-0.0	-1.4	-0.4	-0.8	0.5	-0.3	-0.8	-0.1	-0.5	-0.1	0.7	-1.4	-1.2	0.5	0.7	1.5
Ever had hysterectomy (womb removed)	0.3	0.4	2.0	0.4	-0.4	-0.3	-0.3	-0.1	1.4	-1.4	0.7	0.2	-0.4	0.4	-0.5	0.6	-0.1	0.0	0.5
Systolic blood pressure, automated reading	2.6	7.5	16.7	-2.6	-1.3	-3.1	-3.2	-3.0	-4.1	-3.1	-2.3	-2.6	2.4	-3.2	-3.5	-2.7	-2.2	-1.3	-1.1
Eye problems/disorders: Diabetes related eye disease	3.5	3.9	8.0	-2.3	0.9	-1.9	-1.6	-2.1	-1.3	-1.1	-2.5	-2.2	2.3	-1.9	-1.8	-0.8	-2.2	-2.8	-2.4
Angina	1.7	2.3	5.5	-1.5	-1.4	-2.3	-1.9	-0.4	-2.4	-1.1	-1.3	-1.7	1.4	-1.4	-1.9	-1.8	-1.0	-0.1	-0.5
Medication for hormone replacement therapy	0.2	0.2	0.7	-0.3	0.9	-0.2	-0.5	-0.2	-0.3	0.8	-0.3	-0.5	0.3	0.4	-0.8	0.0	-0.4	-0.1	0.2
Vitamin and mineral supplements	0.9	1.2	4.1	-1.4	0.6	-0.6	-1.0	-0.8	1.1	-0.1	-1.5	-1.2	1.6	-2.0	-0.2	-0.1	-1.1	0.0	-1.5
Supplements: Zinc	1.2	1.3	2.8	1.4	0.9	0.5	1.0	1.0	-0.5	1.2	1.7	1.5	-1.6	1.2	0.5	1.2	1.0	0.2	1.3
Medication: Co-codamol	0.8	0.9	2.0	-0.8	-1.3	-0.9	-1.2	-0.7	0.6	-1.2	-1.0	-1.1	0.7	-1.1	-0.9	-1.4	-0.2	-0.6	-0.4
Medication: Metformin	2.1	2.9	5.3	-2.0	-0.1	-1.7	-1.9	-1.8	-1.0	-1.3	-1.9	-1.9	2.1	-2.3	-1.3	-1.5	-1.6	-1.6	-2.1
Diabetes (father)	0.4	0.5	1.7	-1.1	-0.0	-0.4	-0.3	0.5	-0.6	-0.3	-1.3	-1.0	1.0	-0.7	-0.4	-1.1	-0.0	-0.1	-0.5
Diabetes (mother)	0.2	0.3	1.5	-0.1	0.2	0.6	0.5	1.2	0.3	-0.2	0.2	0.2	0.0	-0.1	0.4	-1.0	0.8	-0.6	0.0
Severe depression (siblings)	0.6	0.7	1.5	-1.0	0.5	-0.4	-0.4	-1.0	0.2	-1.2	-1.0	-0.8	1.1	-0.1	-0.3	0.2	-1.2	-1.2	-1.2
Pack years adult smoking proportion	3.2	5.0	7.7	-2.4	-0.3	-2.4	-2.4	-1.8	-1.6	-2.3	-2.1	-2.2	2.4	-2.7	-2.0	-2.2	-2.4	-2.4	-2.8
Impedance of leg (right)	0.1	0.6	4.5	0.7	-2.1	0.2	-0.4	0.2	-1.4	-0.3	1.0	0.7	-0.7	0.2	0.1	-0.2	0.2	0.3	0.1
Leg fat-free mass (left)	0.5	2.4	6.9	-2.0	0.8	-2.6	-0.8	-1.0	-1.5	-0.9	-2.1	-1.8	1.8	-1.4	-1.6	-2.0	-0.6	-1.4	-0.6
Trunk fat percentage	3.6	14.4	21.2	-4.4	-2.7	-4.6	-4.0	-3.5	-3.8	-3.2	-4.5	-4.6	4.2	-3.8	-4.4	-4.3	-3.0	-2.1	-2.3
Hand grip strength (right)	0.2	0.6	6.3	0.4	-2.5	-0.3	0.2	0.3	-1.0	-0.6	0.8	0.6	-0.5	0.3	0.2	-0.3	0.0	-0.6	-0.2
Townsend deprivation index at recruitment	0.8	1.1	2.9	-0.9	-0.8	-1.2	-0.7	-1.3	-1.4	-1.7	-1.1	-1.0	0.8	-0.6	-1.0	-1.5	-0.0	-0.6	-0.0
Current tobacco smoking	0.5	0.8	3.0	0.3	-1.7	-1.2	0.1	0.7	-1.7	-0.7	0.6	0.5	-0.7	0.2	-0.5	-1.4	0.8	0.0	0.8
Average weekly fortified wine intake	1.0	1.2	9.7	-0.6	-3.1	-1.6	-0.8	0.3	-1.5	-0.4	-0.8	-0.8	0.5	0.1	-0.9	-0.7	-0.3	0.7	0.3
Maternal smoking around birth	3.9	5.6	8.7	-2.5	-1.2	-2.4	-2.2	-2.3	-2.1	-2.3	-2.4	-2.5	2.4	-2.5	-2.5	-2.9	-1.9	-2.9	-2.2
Fed-up feelings	0.6	1.2	6.7	-0.7	-1.3	-1.3	-0.0	1.0	-1.8	-0.8	-0.3	-0.3	0.5	-1.4	-0.3	-2.6	0.8	-0.2	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	3.8	1.2	-0.7	0.2	1.2	1.9	-1.1	0.9	1.8	1.6	-1.5	0.8	0.9	-0.2	1.6	0.4	1.2
Relative age voice broke	2.7	4.2	8.6	1.7	-0.1	2.7	2.3	2.7	1.3	2.9	1.8	2.0	-1.8	0.5	2.7	1.0	2.8	2.1	1.5
Taking other prescription medications	7.2	11.1	17.6	-3.8	-1.2	-4.2	-3.2	-3.9	-3.2	-3.6	-3.6	-3.6	3.7	-3.2	-3.2	-2.6	-3.2	-2.9	-2.9
Age when periods started (menarche)	2.0	4.8	11.2	2.4	1.5	1.7	1.8	3.4	1.0	1.9	2.3	2.1	-2.6	2.1	1.5	0.5	3.2	1.8	3.0
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	2.0	1.2	-0.1	0.4	-0.1	0.3	1.1	-1.4	1.4	0.9	-1.3	1.3	-0.7	0.5	0.5	-0.2	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.1	0.3	1.1	0.1	-0.0	-0.0	-0.3	0.3	0.4	0.3	-0.3	0.5	0.0	0.6	0.1	0.7	0.7
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	6.1	0.1	2.5	0.0	-0.2	-0.5	0.1	0.1	0.1	-0.0	-0.0	-0.0	-0.1	0.7	-0.2	0.4	0.3
Qualifications: CSEs or equivalent	0.1	0.1	0.3	-0.4	-0.2	-0.4	-0.0	-0.1	-0.2	-0.5	-0.5	-0.3	0.4	-0.3	0.2	-0.5	0.1	0.2	-0.2
Serious illness, injury or assault to yourself	1.8	2.2	5.4	-1.4	-2.3	-2.2	-2.0	-0.8	-1.5	-1.4	-1.4	-1.8	1.2	-1.1	-1.7	-1.8	-0.7	0.3	-0.6
High blood pressure	2.2	6.1	10.0	-2.9	-1.2	-3.2	-2.7	-2.0	-3.1	-2.2	-2.6	-2.9	2.6	-3.0	-3.0	-3.0	-1.3	-0.7	-0.8
Hayfever, allergic rhinitis or eczema	0.7	1.6	3.3	-1.2	-1.8	-1.3	-1.3	-1.5	-0.7	-1.1	-1.5	-1.5	1.2	-0.7	-1.6	-1.4	-1.1	-0.5	-0.8
Multivitamins +/- minerals	0.7	0.9	3.7	1.3	-0.2	0.4	0.6	0.4	-0.4	0.4	1.4	1.0	-1.4	1.9	-0.0	0.1	0.9	0.3	1.5
Stomach or abdominal pain in last month	1.6	1.9	3.2	-1.7	-0.2	-1.7	-0.9	-1.4	-0.3	-1.8	-1.5	-1.3	1.8	-1.6	-0.7	-1.3	-1.1	-1.6	-1.7
Supplements: Glucosamine	1.4	1.8	4.2	1.5	0.5	1.4	1.6	2.0	1.0	1.5	1.4	1.4	-1.5	1.4	1.4	0.3	1.6	0.4	1.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	3.4	-0.0	1.8	-0.0	0.1	-0.1	0.5	0.3	-0.3	0.1	0.1	1.0	0.2	1.9	-0.7	0.4	0.3
Medication: Atenolol	1.7	2.1	3.7	-1.9	0.3	-1.3	-1.4	-1.3	-1.0	-1.3	-1.7	-1.8	1.9	-1.4	-1.4	-0.5	-1.8	-1.2	-1.7
Medication: Levothyroxine sodium	3.3	5.6	13.2	-1.6	-0.8	-3.2	-2.5	-2.1	-3.4	-3.4	-1.7	-1.9	1.3	-1.7	-3.6	-3.5	-1.4	-2.0	-0.2
Sitting height	0.1	0.4	2.5	-0.1	1.6	-0.3	0.7	-0.1	-0.8	-0.0	-0.1	0.3	-0.0	-0.5	0.5	-0.5	0.8	-0.8	0.2
Chronic bronchitis/emphysema (father)	0.4	0.5	3.1	-0.1	-1.0	-0.1	0.2	1.8	-0.3	-0.3	-0.3	-0.2	0.0	-0.2	0.3	-1.1	1.0	0.7	0.3
High blood pressure (mother)	0.3	0.4	1.3	-0.2	-0.6	-0.6	0.2	-1.1	-1.1	-0.9	0.2	0.2	0.1	-0.2	0.0	0.1	-0.4	-0.9	-0.7
Body mass index (BMI)	2.4	10.4	20.2	-4.3	-0.1	-3.7	-3.1	-3.0	-1.6	-2.2	-4.5	-4.4	4.2	-3.4	-3.5	-3.3	-2.8	-1.7	-2.2
Impedance of leg (left)	0.2	1.0	5.7	1.2	-2.4	0.6	-0.1	0.3	-0.8	-0.2	1.6	1.2	-1.3	0.6	0.3	0.1	0.5	0.7	0.6
Leg predicted mass (left)	0.5	2.5	6.8	-2.1	0.9	-2.6	-0.8	-1.0	-1.6	-0.9	-2.1	-1.8	1.8	-1.5	-1.6	-2.0	-0.6	-1.5	-0.7
Trunk fat mass	3.1	13.2	21.6	-4.4	-2.0	-4.7	-3.7	-3.2	-3.6	-2.9	-4.4	-4.4	4.1	-3.8	-4.1	-4.3	-2.6	-2.1	-2.1
Waist circumference	2.5	9.0	15.1	-3.8	-0.9	-3.6	-3.0	-3.1	-2.2	-2.1	-3.8	-3.9	3.6	-3.2	-3.4	-3.4	-2.4	-1.6	-2.0
Number of incorrect matches in round	0.9	1.5	2.6	-1.5	-0.8	-1.2	-1.5	-1.1	-0.6	-1.4	-1.6	-1.6	1.5	-1.4	-1.0	-1.2	-0.8	-0.4	-1.1
Past tobacco smoking	1.6	3.0	7.2	2.0	1.7	1.2	1.4	1.8	0.7	2.1	2.0	2.2	-1.9	1.5	2.0	2.7	0.9	1.2	1.1
Alcohol usually taken with meals	0.1	0.2	0.8	0.3	0.5	0.5	0.2	-0.8	0.3	0.3	0.5	0.3	-0.2	0.7	0.1	0.9	-0.6	-0.1	-0.1
Nervous feelings	0.2	0.4	1.5	0.3	-0.6	0.2	1.0	1.2	-0.6	0.7	0.3	0.6	-0.4	0.9	0.7	0.7	0.2	0.4	0.1
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.2	7.0	1.7	-0.3	1.4	2.5	2.6	0.8	1.0	2.0	2.2	-1.8	2.1	2.1	1.1	2.1	1.3	1.5
Hearing difficulty/problems with background noise	0.6	0.9	3.0	0.5	-0.8	0.5	1.1	1.1	-0.1	1.7	0.6	0.7	-0.6	1.4	0.8	0.6	0.9	1.3	1.2
Hair/balding pattern: Pattern 2	0.2	0.3	0.9	-0.2	-0.9	-0.2	-0.5	-0.9	-0.7	-0.8	-0.1	-0.3	0.1	0.0	-0.7	-0.0	0.1	0.5	1.0
Had menopause	0.8	1.0	4.4	0.9	-1.3	0.2	0.1	0.9	0.0	0.4	1.0	0.5	-1.0	1.5	-0.4	0.5	0.8	1.6	2.1
Had other major operations	1.1	1.3	3.5	1.1	-1.2	1.5	1.8	1.6	0.4	0.3	1.0	1.2	-1.1	1.9	1.3	0.8	0.9	0.5	0.7
Forced vital capacity (FVC)	0.7	2.8	9.1	-1.5	-0.4	-1.9	-0.8	-1.3	-2.2	-2.4	-1.5	-1.3	1.4	-0.5	-1.6	-2.1	-1.2	-3.0	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	1.0	0.2	1.0	-0.3	-0.3	0.1	-0.4	-0.1	0.3	0.2	-0.2	0.3	-0.3	0.3	-0.1	0.4	0.6
Ever unenthusiastic/disinterested for a whole week	2.4	2.9	5.9	-1.9	0.0	-1.9	-1.7	-2.1	-0.8	-1.6	-1.6	-1.7	1.9	-2.4	-1.5	-1.7	-1.7	-1.6	-1.9
Qualifications: None of the above	0.5	1.0	11.4	-0.6	-3.4	-0.5	-0.1	-0.1	-1.1	-1.2	-0.5	-0.4	0.5	-0.1	-0.2	-0.4	-0.4	0.1	-0.4
Financial difficulties in last 2 years	0.4	0.6	2.3	-0.8	1.2	-0.5	0.4	-0.7	-0.1	0.5	-0.5	-0.1	0.8	-1.1	0.7	0.5	-0.6	-0.9	-1.5
Mouth/teeth dental problems	0.1	0.1	0.6	0.1	-0.8	-0.0	-0.3	0.0	-0.8	-0.3	0.3	0.1	-0.1	0.3	-0.4	0.1	-0.5	-0.5	-0.2
Heart attack	2.3	3.0	6.0	-2.1	-0.9	-1.8	-1.4	-1.2	-1.9	-1.6	-1.8	-1.8	2.1	-1.6	-1.2	-1.4	-2.1	-1.7	-2.5
Allergy	2.7	6.2	10.0	2.5	1.6	2.8	2.7	3.2	1.5	2.7	2.6	2.7	-2.5	2.5	2.7	2.4	2.5	2.0	2.3
Pain all over the body in last month	1.2	1.3	2.7	1.5	-0.8	0.7	0.5	1.3	0.3	1.2	1.6	1.4	-1.6	1.5	0.5	0.5	1.0	1.2	1.2
Diabetes (self-reported)	0.8	1.2	2.4	-1.2	1.6	-1.1	-0.8	-0.7	-1.1	-0.4	-1.1	-1.1	1.2	-1.4	-0.8	-1.4	-0.5	-1.3	-1.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	3.5	-0.6	-0.5	-0.8	-0.9	-1.9	0.3	-1.1	-0.6	-0.6	0.6	-1.2	-0.6	-0.9	-0.6	-0.5	-0.7
Medication: Ramipril	0.4	0.5	1.1	-0.8	0.2	-0.2	0.4	1.0	0.1	1.1	-0.7	-0.2	0.9	-0.6	0.8	0.9	-0.6	0.2	-1.0
Medication: Simvastatin	1.0	1.4	4.8	-1.2	-2.2	-1.2	-0.9	-0.1	-1.0	-1.0	-1.4	-1.4	1.1	-0.9	-1.1	-2.2	0.1	-0.2	-0.5
Fluid intelligence score	0.5	1.1	2.6	-0.9	0.5	-1.4	-1.4	-1.3	-0.7	-1.3	-1.0	-1.2	0.9	-0.1	-1.6	-0.0	-1.4	-0.3	-0.3
Illnesses of siblings	4.0	5.6	10.1	3.2	1.7	2.5	2.4	1.9	1.4	2.0	2.8	3.0	-3.2	2.8	2.1	1.9	2.3	1.2	2.4
Neuroticism score	0.3	0.7	3.4	-0.7	-1.2	-1.3	-0.1	0.8	-1.8	-0.5	-0.4	-0.2	0.4	-0.6	-0.2	-1.6	0.4	-0.3	-0.4
Weight	1.8	9.0	17.4	-3.7	-0.5	-4.2	-2.7	-2.4	-2.8	-2.3	-3.8	-3.7	3.5	-3.0	-3.4	-3.7	-2.1	-2.1	-1.6
Impedance of arm (right)	0.3	1.6	11.2	0.3	-3.3	-0.6	-0.9	-0.3	-2.9	-1.4	0.5	0.2	-0.5	0.4	-0.8	-0.7	-0.4	-0.5	-0.1
Arm fat percentage (right)	3.5	13.8	23.3	-4.6	-1.9	-4.3	-3.8	-3.5	-3.1	-3.1	-4.8	-4.8	4.4	-3.5	-4.1	-3.8	-3.2	-1.9	-2.5
Trunk fat-free mass	0.1	0.7	3.8	-1.0	2.0	-1.6	0.1	0.1	-0.5	0.1	-0.8	-0.5	0.8	-0.7	-0.4	-0.9	-0.0	-1.0	-0.2
Hip circumference	1.9	8.1	15.5	-3.4	-0.8	-3.9	-2.4	-2.6	-2.6	-2.3	-3.5	-3.4	3.2	-2.7	-3.3	-3.7	-2.0	-2.0	-1.5
Time employed in main current job	0.4	0.4	2.3	-0.6	0.8	-0.2	-0.1	0.3	1.5	0.3	-0.9	-0.8	0.8	-0.1	-0.2	-0.8	-0.2	-0.4	-0.6
Alcohol intake versus 10 years previously	0.9	1.4	2.6	-1.2	-1.1	-1.5	-1.0	-1.0	-1.4	-1.3	-0.9	-1.0	1.0	-1.6	-0.9	-1.5	-0.7	-0.9	-1.3
Father’s age at death	2.1	2.9	5.4	1.6	1.1	2.3	2.1	1.3	1.5	2.1	1.5	1.8	-1.5	1.6	1.9	2.1	1.3	1.5	1.4
Worrier / anxious feelings	0.2	0.3	1.3	-0.6	-0.7	-0.5	-0.0	0.1	-0.7	0.3	-0.2	-0.1	0.6	-0.5	-0.0	-0.5	-0.6	-0.9	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.3	-0.1	-0.4	-0.1	0.6	1.1	0.1	0.2	0.5	0.4	-0.0	0.2	0.5	-0.5	0.7	0.3	0.2
Falls in the last year	0.3	0.4	2.0	-0.2	1.4	-0.0	0.6	0.4	1.0	1.1	-0.1	-0.2	0.2	-0.1	0.3	0.1	0.7	0.8	0.4
Hair/balding pattern: Pattern 3	0.3	0.5	3.0	0.1	1.7	0.3	0.8	0.2	0.7	0.4	0.4	0.6	-0.0	-0.2	0.6	0.5	-0.4	-1.1	-0.9
Number of live births	0.5	0.8	3.7	-0.3	-1.9	-0.8	-1.0	-1.6	-0.2	-0.6	-0.4	-0.7	0.4	-1.0	-1.0	-0.5	-0.4	0.8	0.1
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	8.8	-1.2	-0.5	-1.9	-0.6	-1.3	-2.6	-2.1	-1.3	-1.0	1.0	-0.0	-1.5	-1.9	-1.3	-3.0	-1.1
Pulse rate	0.4	0.7	2.9	0.6	0.0	1.2	0.4	0.6	1.7	1.3	0.2	0.1	-0.5	0.8	0.2	0.6	0.5	1.5	1.1
Happiness	0.5	0.6	1.3	0.8	-1.1	0.0	0.8	1.1	-0.7	1.1	1.1	1.0	-0.8	0.1	0.6	-0.5	1.0	0.4	0.5
Noisy workplace	0.6	0.8	1.6	-0.9	-1.3	-0.7	-0.9	-0.6	-1.1	-1.2	-0.9	-1.0	0.9	-0.2	-1.1	-1.1	-0.9	-0.3	-0.3
Qualifications: A levels/AS levels or equivalent	1.1	2.4	7.4	1.9	2.7	1.3	1.2	1.0	1.1	1.3	1.8	1.7	-1.9	1.8	0.9	1.2	1.3	0.8	1.7
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.1	-0.9	0.5	-0.9	-1.3	-0.6	0.1	-0.7	-1.4	-1.5	0.9	-0.6	-1.3	-1.0	-0.8	0.4	-0.1
Mouth/teeth dental problems: Dentures	1.7	2.8	5.8	-1.9	0.2	-2.2	-1.9	-1.6	-0.4	-1.9	-2.3	-2.4	1.9	-1.1	-2.2	-1.8	-1.2	-0.8	-0.5
Asthma	3.6	7.0	13.0	-2.8	-1.0	-2.5	-2.6	-3.5	-0.8	-2.5	-2.5	-2.6	2.9	-3.2	-2.1	-2.1	-3.1	-2.9	-3.6
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	3.5	-0.7	0.4	-1.1	-1.1	-1.8	-0.5	-1.5	-0.7	-0.9	0.6	-1.9	-1.3	-1.8	-0.5	-1.5	-0.8
Medication: Cholesterol lowering	1.1	1.7	4.3	-1.3	-1.3	-1.5	-1.6	-0.4	-1.8	-0.7	-1.3	-1.4	1.2	-2.1	-1.2	-2.0	-0.0	-0.0	-0.6
Depression (self-reported)	0.5	0.7	4.3	-0.0	2.1	0.6	0.3	0.4	1.0	1.1	-0.0	0.2	0.2	-0.2	1.0	1.1	0.2	1.0	-0.0
Medication: Lansoprazole	0.5	0.6	1.9	-0.6	1.1	-0.5	-0.4	-0.9	-0.5	-0.4	-0.5	-0.5	0.6	-1.4	-0.2	-1.0	0.0	-1.1	-0.8
Prospective memory result	0.4	0.5	1.6	-1.0	-0.5	0.2	-0.4	-0.5	0.5	0.3	-1.3	-1.0	1.1	-0.8	-0.0	-0.1	-0.5	0.3	-0.8
Lung cancer (father)	0.6	0.8	8.1	0.1	-2.8	-0.4	0.3	0.9	0.2	-0.8	0.5	0.3	-0.1	0.1	0.3	-0.7	-0.1	-0.8	-0.7
Illnesses of mother	2.2	2.8	5.4	1.8	0.9	1.8	1.6	1.1	1.7	2.0	1.5	1.7	-1.7	2.3	1.4	2.3	0.8	1.7	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	3.4	0.0	0.2	-0.5	0.1	-0.2	-1.4	-0.5	-0.2	-0.1	-0.1	0.7	-0.7	-1.3	0.1	-1.8	0.1
Pulse wave Arterial Stiffness index	0.5	0.5	2.6	0.6	-0.0	1.0	0.4	-0.5	1.6	0.8	0.4	0.2	-0.5	0.3	0.4	0.6	0.9	0.8	0.9
Impedance of arm (left)	0.3	1.4	11.0	0.6	-3.3	-0.1	-0.4	0.1	-2.6	-1.0	0.9	0.7	-0.8	0.6	-0.3	-0.2	-0.1	-0.4	0.0
Arm fat mass (right)	2.5	10.5	18.2	-4.1	-1.0	-4.2	-3.3	-2.8	-2.6	-2.6	-4.3	-4.3	3.9	-3.2	-3.7	-3.5	-2.6	-1.5	-1.9
Trunk predicted mass	0.1	0.6	3.8	-0.8	1.9	-1.4	0.3	0.2	-0.4	0.2	-0.7	-0.4	0.7	-0.6	-0.3	-0.8	0.1	-1.0	-0.1
Standing height	0.1	1.5	8.2	0.8	-0.9	-1.4	0.7	1.1	-2.9	-0.2	1.2	1.3	-1.2	0.7	0.1	-1.2	1.3	-0.9	1.0
Length of working week for main job	2.5	2.8	8.2	-1.1	-1.2	-1.6	-1.3	-1.2	-1.8	-2.9	-0.7	-0.9	1.0	-0.7	-1.7	-1.9	-1.7	-2.9	-2.0
Exposure to tobacco smoke at home	0.4	0.5	1.4	0.0	-0.4	0.3	0.7	-0.6	-0.7	-0.9	0.5	0.7	-0.0	-1.0	0.7	-0.0	-0.3	-1.1	-1.2
Breastfed as a baby	1.1	1.3	5.6	0.7	0.5	1.5	0.8	0.4	1.1	2.4	0.7	0.8	-0.6	0.7	1.1	2.1	0.5	1.4	1.0
Tense / ‘highly strung’	0.1	0.2	0.7	-0.5	0.4	-0.4	0.3	0.6	-0.7	0.3	-0.3	-0.1	0.4	-0.2	0.3	-0.3	-0.1	-0.8	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	3.1	4.7	9.6	-2.2	-1.1	-3.1	-2.5	-2.7	-2.0	-2.3	-2.1	-2.4	2.1	-2.1	-2.6	-2.7	-1.2	-1.0	-1.0
Hair/balding pattern: Pattern 4	0.6	1.5	4.9	-1.1	1.7	-0.6	-1.1	-2.2	0.6	1.2	-1.2	-1.4	1.2	-2.0	-0.6	-1.0	-0.6	-0.7	-1.2
Birth weight of first child	1.4	2.5	5.9	-1.6	-1.1	-1.8	-2.1	-1.2	-1.5	-1.3	-1.8	-2.0	1.4	-1.5	-2.4	-2.4	-0.5	-0.7	-0.0
Peak expiratory flow (PEF)	1.7	3.9	9.0	-2.0	-0.2	-2.7	-1.8	-2.1	-3.0	-1.7	-1.8	-1.8	1.8	-0.7	-2.4	-1.8	-2.1	-2.4	-1.2
Pulse wave reflection index	0.3	0.3	0.8	0.6	0.0	0.8	0.6	-0.2	0.5	0.4	0.7	0.8	-0.6	0.0	0.9	0.5	0.9	0.1	0.3
Ever highly irritable/argumentative for 2 days	2.1	2.5	4.7	-1.5	-1.7	-2.1	-1.9	-1.9	-2.2	-1.4	-1.2	-1.5	1.3	-0.8	-2.0	-1.6	-1.5	-0.7	-0.8
Loud music exposure frequency	0.4	0.5	1.6	0.4	1.1	0.8	1.0	-0.4	0.8	0.4	0.3	0.4	-0.3	1.1	0.4	1.3	-0.3	-0.5	-0.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.5	0.1	1.2	-0.8	-0.3	0.0	-1.0	-0.2	0.2	0.1	-0.2	0.5	-0.9	-0.4	-0.3	-1.0	0.4
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.3	1.3	0.6	1.0	1.3	1.1	1.2	1.3	1.2	1.4	-1.2	0.5	1.5	1.0	1.5	1.4	1.0
Blood clot in the leg (DVT)	0.2	0.2	0.9	0.5	0.4	-0.4	-0.2	0.1	-0.7	-0.2	0.7	0.3	-0.6	0.4	-0.4	0.4	0.4	0.5	1.0
Medication: Paracetamol	5.7	9.4	16.6	-3.2	-1.3	-3.1	-3.2	-3.3	-2.8	-3.1	-3.2	-3.3	3.2	-3.6	-3.3	-4.1	-2.4	-2.4	-2.4
Headache pain in last month	0.1	0.2	0.7	0.1	0.2	0.2	0.6	0.1	0.7	0.3	-0.2	0.1	-0.0	-0.3	0.4	-0.6	0.8	0.0	0.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	2.7	1.3	0.7	1.1	0.8	-0.4	0.9	-0.6	1.4	1.1	-1.2	1.6	0.1	0.8	0.1	-0.3	0.9
Glaucoma (self-reported)	0.3	0.4	0.9	-0.7	0.4	-0.4	-0.6	-0.8	-0.0	-0.7	-0.9	-0.9	0.8	-0.5	-0.6	0.1	-0.8	-0.4	-0.4
Gout (self-reported)	1.0	1.4	3.2	-1.1	1.0	-1.4	-1.8	-1.5	-0.7	-1.1	-1.4	-1.6	1.1	-0.2	-1.6	0.1	-1.4	0.3	-0.1
Hypothyroidism/myxoedema (self-reported)	2.5	4.8	11.3	-1.9	-1.1	-3.0	-2.2	-1.8	-3.0	-2.6	-2.0	-2.1	1.6	-1.5	-3.3	-3.4	-1.2	-1.6	-0.1
Medication: Amlodipine	1.3	1.9	3.6	-1.5	-0.1	-1.4	-1.2	-1.0	-1.4	-1.7	-1.9	-1.8	1.5	-1.6	-1.8	-1.7	-0.6	-0.5	-0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.7	0.3	0.2	0.0	-0.3	-0.6	0.8	-0.4	0.2	0.0	-0.3	-0.3	-0.2	-0.2	0.0	0.5	0.0
Birth weight	0.2	0.4	2.0	0.7	0.8	0.4	-0.2	0.5	-0.5	0.2	0.3	0.3	-0.8	1.1	-0.8	-0.2	0.5	-0.0	1.4
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.5	-0.1	-0.9	-0.6	-0.7	0.1	-0.5	-1.0	0.3	-0.1	0.0	-1.2	-0.5	-1.2	0.6	0.5	0.2
High blood pressure (siblings)	1.0	1.4	2.6	-1.6	-1.3	-1.6	-1.1	-0.7	-0.3	-1.3	-1.4	-1.5	1.6	-1.1	-1.2	-0.9	-1.2	-0.2	-0.8
Forced vital capacity (FVC), Best measure	0.2	0.8	5.9	-0.6	0.5	-0.6	0.2	-0.4	-0.9	-0.9	-0.7	-0.4	0.5	0.1	-0.5	-1.3	-0.3	-2.4	-0.8
Body fat percentage	3.8	15.1	24.0	-4.7	-2.2	-4.5	-4.0	-3.7	-3.3	-3.3	-4.8	-4.9	4.5	-3.9	-4.4	-4.2	-3.2	-2.2	-2.5
Leg fat percentage (right)	3.6	12.9	23.0	-4.6	-0.9	-4.0	-3.6	-3.5	-2.4	-2.7	-4.8	-4.8	4.5	-4.0	-3.9	-3.9	-2.9	-1.9	-2.5
Arm fat-free mass (right)	0.2	1.0	3.5	-1.4	1.5	-1.9	-0.3	-0.3	-0.4	-0.2	-1.3	-1.1	1.2	-1.0	-0.9	-1.3	-0.1	-0.8	-0.1
Exposure to tobacco smoke outside home	2.1	2.8	5.0	-2.2	-0.7	-1.8	-1.7	-1.5	-0.9	-1.4	-2.2	-2.2	2.2	-1.3	-1.4	-0.4	-2.1	-1.6	-1.8
Comparative body size at age 10	0.3	1.0	2.6	0.9	0.0	1.2	1.4	1.6	0.9	0.9	0.6	0.9	-0.9	0.5	1.3	0.2	1.4	0.4	0.6
Number of full brothers	1.2	1.5	3.9	-1.5	0.1	-0.9	-0.9	-1.4	-0.1	-0.7	-1.6	-1.4	1.6	-1.7	-0.4	-0.5	-1.2	-1.1	-2.0
Worry too long after embarrassment	0.4	0.6	2.3	-0.8	-1.5	-0.9	-0.4	-0.2	-0.8	-0.2	-0.9	-0.7	0.8	-1.0	-0.1	-1.3	0.0	-0.2	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.5	-1.0	-0.4	-1.6	-0.7	-0.2	-1.2	-0.1	-1.1	-1.0	0.9	-0.4	-0.9	-0.6	-0.8	0.6	-0.0
Wheeze or whistling in the chest in last year	1.4	2.4	6.1	-2.0	-0.7	-1.9	-1.3	-1.4	-0.3	-1.1	-1.8	-1.7	2.0	-2.5	-0.9	-2.0	-1.1	-0.8	-1.8
Number of children fathered	2.2	2.4	4.0	-1.6	0.2	-1.7	-1.8	-1.7	-1.9	-1.3	-1.5	-1.5	1.5	-1.4	-1.8	-1.1	-2.0	-1.6	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.2	-0.7	0.3	0.3	-0.8	-1.0	0.9	0.1	-0.9	-1.1	0.8	-0.8	-0.6	-0.2	-0.7	-0.1	-0.5
Age at first live birth	6.6	11.6	21.0	3.6	3.3	4.0	3.7	3.0	2.9	4.6	3.6	3.9	-3.6	3.1	3.8	3.0	3.3	1.7	2.5
Pulse wave peak to peak time	0.7	0.8	3.7	-0.8	-0.2	-1.3	-0.7	0.4	-1.9	-1.0	-0.5	-0.4	0.7	-0.5	-0.7	-0.9	-1.1	-1.1	-1.0
Health satisfaction	0.6	0.7	2.3	-0.3	-0.6	-1.4	-0.8	-0.8	-1.5	-1.0	-0.1	-0.4	0.1	-0.8	-1.4	-1.1	-0.0	-0.8	0.2
Shortness of breath walking on level ground	1.6	1.9	4.7	-1.3	0.2	-2.2	-2.1	-1.2	-0.2	-1.5	-1.3	-1.5	1.2	-1.5	-1.9	-1.2	-1.0	-1.1	-0.7
Qualifications: College or University degree	0.8	2.7	10.9	1.8	3.3	1.3	1.4	0.2	1.9	1.6	1.6	1.6	-1.6	1.6	1.4	2.2	0.9	0.4	0.9
Eye problems/disorders: None of the above	7.6	8.7	14.0	2.9	1.7	3.5	3.5	3.1	2.9	3.5	2.8	3.2	-2.8	2.9	3.7	3.1	2.5	2.2	1.9
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.4	0.3	0.2	-0.7	-0.0	-0.0	0.1	-0.1	0.3	0.3	-0.3	-0.3	0.1	0.0	0.4	-0.3	-0.0
Emphysema/chronic bronchitis	2.9	3.2	7.2	-2.0	-1.2	-1.9	-1.6	-1.8	-1.4	-2.2	-2.0	-2.0	1.9	-2.5	-1.5	-2.7	-0.7	-0.9	-1.3
Medication for pain relief, constipation, heartburn	3.3	5.7	9.0	2.8	0.8	2.5	2.3	2.5	2.1	2.1	2.9	2.7	-2.7	3.0	2.3	2.9	1.8	1.8	2.0
Neck or shoulder pain in last month	0.1	0.1	0.5	0.0	-0.0	0.0	0.2	-0.0	0.7	0.2	0.3	0.2	0.1	-0.2	0.4	-0.2	0.1	-0.5	-0.5
Medication: Blood pressure	1.1	2.0	4.2	-1.8	-0.6	-1.9	-1.6	-0.6	-1.6	-0.1	-1.9	-1.8	1.7	-2.1	-1.1	-1.4	-0.8	-0.3	-1.1
Angina (self-reported)	2.0	2.6	7.8	-1.5	-1.8	-2.5	-1.9	-0.4	-2.8	-1.1	-1.2	-1.7	1.3	-1.4	-2.0	-2.1	-0.9	-0.2	-0.5
Migraine (self-reported)	3.4	4.2	10.1	-1.8	-2.0	-1.9	-2.2	-2.1	-3.2	-1.1	-1.9	-1.8	1.6	-3.1	-1.9	-2.6	-1.1	-1.5	-1.7
Medication: Ibuprofen	0.4	0.5	3.1	-0.2	-0.0	-0.8	-0.2	-1.8	-0.4	-1.0	-0.3	-0.2	0.2	-1.0	-0.6	-0.5	-0.4	-1.1	-0.4
Medication: Allopurinol	1.0	1.4	3.0	-1.4	1.4	-1.1	-1.3	-1.5	-1.0	-0.8	-1.7	-1.7	1.4	-0.8	-1.2	-0.3	-1.2	0.2	-0.4
Medication: Omeprazole	0.3	0.3	1.5	0.3	-0.0	-0.6	-1.2	-0.4	-0.2	0.3	0.2	-0.3	-0.3	0.4	-1.2	0.0	-0.3	0.7	0.8
Medication: Seretide 50 evohaler	1.1	1.3	8.6	-1.2	2.9	-0.1	-0.3	-0.8	0.5	-0.4	-1.2	-1.1	1.3	-1.2	-0.4	-0.1	-0.8	-1.1	-1.2
Mean time to correctly identify matches	2.2	4.1	6.5	2.0	2.0	2.5	2.4	2.0	1.8	2.2	1.7	2.0	-2.0	1.4	2.2	1.6	2.5	1.7	2.0
Heart disease (mother)	1.1	1.3	3.0	-1.4	-1.7	-0.8	-1.3	-0.6	-0.8	-0.9	-1.5	-1.5	1.4	-1.5	-0.8	-1.4	-0.6	-0.2	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	5.0	-0.6	-2.2	-1.9	-1.9	-0.8	-1.6	-1.6	0.0	-0.7	0.4	-0.6	-2.0	-1.3	-1.0	-0.5	-0.1
Whole body fat mass	3.0	12.4	20.5	-4.4	-1.6	-4.5	-3.5	-3.1	-3.1	-2.9	-4.4	-4.4	4.1	-3.6	-4.1	-4.0	-2.7	-2.0	-2.0
Leg fat mass (right)	2.9	11.1	19.7	-4.3	-0.5	-4.2	-3.3	-3.1	-2.4	-2.5	-4.4	-4.4	4.1	-3.5	-3.7	-3.7	-2.4	-1.6	-1.9
Arm predicted mass (right)	0.2	1.1	3.9	-1.3	1.6	-2.0	-0.4	-0.3	-0.6	-0.1	-1.2	-1.1	1.1	-1.2	-1.0	-1.4	-0.1	-0.8	-0.1
Pulse rate, automated reading	0.4	1.3	5.6	0.8	-2.0	0.0	-0.3	0.5	-0.2	0.3	0.8	0.1	-0.9	0.5	-0.8	-1.0	1.3	2.4	2.2
Alcohol intake frequency.	2.5	5.8	10.1	-2.6	0.1	-2.7	-2.6	-2.9	-2.5	-3.2	-2.4	-2.6	2.5	-2.2	-2.7	-1.7	-2.3	-2.2	-1.7
Comparative height size at age 10	0.1	0.6	1.7	0.7	-0.3	-1.3	0.3	0.3	-1.2	0.1	1.2	1.1	-1.0	1.0	0.1	0.5	0.4	-0.1	0.8
Number of full sisters	0.2	0.2	1.3	-0.3	-0.2	-0.3	-0.1	-0.4	-1.0	-0.7	0.0	-0.0	0.2	0.1	-0.6	-0.3	-0.2	-1.1	-0.1
Suffer from ‘nerves’	0.2	0.3	0.9	0.2	-0.6	-0.3	0.3	0.9	-0.9	0.1	0.3	0.3	-0.4	0.9	-0.2	-0.5	0.6	-0.2	0.5
Overall health rating	0.7	1.6	4.9	-1.5	-0.1	-2.2	-1.3	-0.2	-1.3	-1.1	-1.2	-1.4	1.4	-1.6	-1.2	-1.9	-0.2	0.1	-0.4
Chest pain or discomfort	0.6	0.8	1.9	-1.2	-0.2	-0.9	-0.5	-0.2	-0.4	-1.4	-1.1	-1.0	1.2	-0.8	-0.6	-1.3	-0.6	-1.1	-1.1
Had major operations	0.4	0.4	3.9	-0.2	-2.0	-0.4	0.6	0.9	-0.5	-0.7	0.0	0.3	0.1	0.3	0.6	-0.0	-0.1	-0.1	-0.6
Age at last live birth	4.3	6.3	11.6	2.7	2.9	2.5	2.5	2.1	1.9	3.4	2.8	2.9	-2.6	2.3	2.8	2.8	2.2	1.1	1.8
Family relationship satisfaction	0.9	1.1	2.8	-1.3	-1.7	-1.6	-0.8	-1.1	-1.5	-0.8	-1.2	-1.1	1.2	-0.4	-0.9	-0.3	-0.9	-0.3	-0.6
Leg pain on walking	1.7	2.1	5.6	-1.5	-1.3	-1.9	-0.7	-0.6	-2.4	-1.4	-1.3	-1.4	1.2	-0.6	-1.9	-2.3	-0.4	-1.9	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	3.2	-0.3	-0.4	-0.1	-0.2	0.5	-0.7	-0.1	0.1	-0.1	0.2	-1.6	0.1	-1.8	0.7	-0.0	-0.6
Commuting to job workplace: Car/motor vehicle	0.5	0.6	4.3	0.2	1.0	1.0	0.7	-0.6	2.1	0.7	-0.0	0.1	0.0	0.1	0.9	0.8	-0.0	-0.2	-0.6
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.1	1.2	0.3	1.1	1.1	0.7	-0.0	0.3	1.5	1.4	-1.3	1.0	0.6	0.6	1.2	-0.1	1.3
Medication: Aspirin	1.7	2.3	6.0	-2.3	-0.5	-1.4	-1.2	-1.0	-1.3	-0.4	-2.4	-2.2	2.3	-1.5	-0.9	-0.9	-1.3	-0.6	-1.6
Supplements: Vitamin C	0.4	0.5	1.6	0.8	-0.5	0.1	0.6	0.1	-0.5	-0.3	1.3	1.0	-0.9	1.2	0.3	1.0	0.0	-0.7	0.2
Knee pain experienced in last month	0.7	1.0	3.3	1.0	-0.2	0.8	0.9	1.8	0.7	0.5	0.7	0.7	-1.1	1.3	0.6	-0.1	1.7	0.7	1.5
Hypertension (Self-reported)	2.5	7.0	10.4	-3.2	-0.8	-3.2	-2.9	-2.3	-3.0	-2.2	-3.0	-3.2	3.0	-3.2	-3.1	-3.0	-1.6	-1.1	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	3.1	0.2	-1.8	-0.8	-0.7	-0.6	-0.9	0.6	0.4	0.0	-0.4	0.3	-0.7	-0.1	0.2	0.5	0.8
Illnesses of father: Heart disease	1.3	1.8	4.0	-1.4	-0.2	-1.7	-1.8	-1.1	-1.5	-1.1	-1.4	-1.6	1.4	-0.6	-2.0	-1.1	-1.7	-0.7	-0.6
Illnesses of siblings: Diabetes	0.7	0.9	1.8	-1.1	-1.4	-1.2	-1.2	-1.1	-0.5	-0.3	-0.9	-1.2	1.1	-1.0	-0.7	-0.5	-0.8	0.8	-0.5
Smoking status: Previous	1.8	2.7	5.9	-1.7	-1.8	-1.0	-1.6	-1.7	-0.4	-2.4	-2.0	-2.1	1.7	-1.1	-2.1	-1.9	-1.2	-1.2	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.1	8.7	2.2	-0.7	0.6	2.1	3.0	-0.2	-0.4	2.3	2.4	-2.3	2.7	1.4	0.4	1.7	0.2	1.4
Whole body fat-free mass	0.2	1.3	4.1	-1.4	1.6	-2.0	-0.3	-0.4	-0.9	-0.4	-1.4	-1.1	1.2	-1.1	-0.9	-1.4	-0.2	-1.3	-0.4
Leg fat-free mass (right)	0.3	1.3	4.5	-1.5	1.0	-2.1	-0.4	-0.6	-1.1	-0.6	-1.5	-1.2	1.2	-1.0	-1.2	-1.6	-0.2	-1.1	-0.2
Arm fat percentage (left)	3.4	13.4	22.7	-4.5	-1.6	-4.3	-3.7	-3.4	-3.1	-2.9	-4.8	-4.7	4.4	-3.7	-4.1	-3.7	-3.2	-2.0	-2.5
Average weekly red wine intake	2.2	3.2	7.5	1.9	0.4	2.0	2.2	1.0	1.4	2.3	1.8	2.2	-1.8	2.1	2.2	2.7	0.8	0.9	0.8
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.0	0.5	0.7	-0.6	-0.8	0.2	-1.1	-0.7	0.5	0.0	-0.6	1.0	-0.8	-0.2	0.3	0.7	1.4
Mood swings	1.1	1.9	5.4	-1.3	-0.5	-2.3	-1.6	-0.8	-1.8	-1.7	-0.9	-1.2	1.1	-1.5	-1.5	-2.2	-0.3	-0.7	-0.4
Loneliness, isolation	0.2	0.2	0.7	-0.1	0.7	-0.0	0.6	0.4	-0.2	0.6	-0.0	0.1	0.1	-0.1	0.4	-0.9	0.9	0.5	0.4
Long-standing illness, disability or infirmity	2.4	3.7	7.3	-2.5	0.6	-2.7	-1.8	-1.5	-2.2	-1.5	-2.7	-2.4	2.4	-1.8	-1.7	-1.3	-1.5	-1.1	-1.3
Ever had bowel cancer screening	0.5	0.6	2.4	0.4	0.4	0.6	1.6	0.7	1.0	0.7	0.3	0.6	-0.3	1.1	1.0	0.8	0.9	0.4	0.8
Diabetes diagnosed by doctor	0.8	1.4	2.7	-1.4	1.2	-1.3	-1.2	-0.8	-0.5	-0.7	-1.2	-1.3	1.3	-1.6	-0.9	-1.5	-0.6	-1.2	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.6	-0.1	0.5	-0.1	0.0	-0.8	-0.2	-0.0	0.2	0.1	0.1	-0.4	0.2	0.3	-0.2	-0.4	-0.3
Friendships satisfaction	0.5	0.6	2.6	-0.6	-1.1	-0.6	-0.3	-0.3	-1.6	-1.4	-0.8	-0.8	0.6	-0.3	-0.7	-0.6	-0.4	-0.3	-0.2
Qualifications: nursing, teaching	2.5	3.9	13.1	1.5	3.6	2.3	2.1	1.1	2.5	2.2	1.5	1.4	-1.4	2.5	1.6	2.3	1.2	1.0	1.5
Commuting to job workplace: Walk	0.9	1.0	4.8	-0.3	-2.2	-1.6	-0.9	-0.0	-1.9	-1.2	-0.1	-0.3	0.1	-0.4	-1.2	-0.9	-0.4	-0.5	-0.1
Eye problems/disorders: Cataract	1.1	1.3	3.2	-0.9	-1.8	-1.3	-1.6	-1.3	-1.3	-1.4	-0.7	-1.0	0.8	-0.9	-1.5	-1.2	-0.8	-0.2	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	3.5	-0.1	1.9	0.9	0.8	0.2	0.8	1.7	-0.1	0.3	0.1	-1.0	1.1	-0.2	0.9	-0.0	-0.3
Medication for cholesterol	0.3	0.5	1.7	0.9	0.6	0.5	0.5	0.4	1.3	0.4	0.6	0.7	-0.7	-0.2	1.1	0.7	0.7	0.6	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	3.4	-1.7	0.1	-1.4	-1.1	-1.8	-1.2	-1.1	-1.7	-1.4	1.7	-1.1	-1.1	-0.5	-1.7	-1.9	-1.5
Back pain experienced in last month	1.1	1.6	3.6	-1.6	1.9	-0.4	-0.1	-0.6	0.5	-1.1	-1.9	-1.4	1.7	-1.4	-0.1	-1.3	-0.5	-1.6	-1.4
Mineral and other dietary supplements	0.5	0.7	1.4	-0.9	-0.2	-1.0	-1.1	-1.0	-0.9	-0.2	-1.2	-1.2	0.9	-1.1	-0.9	-0.7	-0.3	0.3	-0.2
Breast cancer (self-reported)	4.5	5.4	8.8	2.8	2.2	2.2	2.4	2.3	2.3	1.6	3.0	2.6	-2.7	2.7	1.6	2.3	2.1	1.0	2.3
Asthma (self-reported)	2.7	5.5	11.2	-2.5	-1.0	-2.2	-2.2	-3.0	-0.5	-2.3	-2.2	-2.2	2.6	-2.9	-1.7	-1.7	-2.8	-2.6	-3.3
Osteoporosis (self-reported)	2.4	3.0	5.7	-1.9	-1.0	-1.7	-2.0	-1.9	-0.9	-2.4	-1.7	-2.0	1.9	-1.3	-2.1	-1.4	-1.8	-1.6	-1.5
Osteoarthritis (self-reported)	3.4	4.4	11.8	-3.2	-0.5	-1.7	-1.3	-1.8	-1.5	-1.5	-3.4	-2.9	3.2	-1.7	-1.3	-1.2	-2.3	-1.2	-2.2
Medication: Aspirin	0.9	1.1	3.6	-1.8	-0.6	-0.7	-0.5	-0.4	-0.9	0.2	-1.9	-1.6	1.8	-0.7	-0.2	0.1	-1.1	-0.2	-1.3
Medication: Gliclazide	0.4	0.4	2.4	0.4	-0.3	-1.1	-0.5	-0.0	-1.2	-1.6	0.5	0.2	-0.5	0.1	-0.5	-0.5	0.4	0.0	0.4
Illnesses of father: None of the above (group 1)	0.6	0.7	2.5	0.5	0.8	1.3	1.1	0.1	1.6	0.6	0.5	0.8	-0.3	-0.6	1.4	1.1	0.6	-0.0	-0.3
Smoking status: Current	0.3	0.5	1.9	0.3	-1.1	-0.8	0.3	0.8	-1.4	-0.4	0.7	0.5	-0.6	0.2	-0.2	-1.2	0.8	-0.0	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	3.8	-0.3	-0.6	0.0	0.7	-0.4	-0.5	-1.0	-0.4	0.0	0.3	-0.2	0.2	-1.4	-0.1	-1.9	-1.0
Whole body water mass	0.2	1.2	3.8	-1.4	1.6	-1.9	-0.2	-0.4	-0.8	-0.3	-1.3	-1.0	1.2	-1.1	-0.8	-1.3	-0.2	-1.2	-0.4
Leg predicted mass (right)	0.2	1.3	4.5	-1.5	1.0	-2.1	-0.4	-0.6	-1.1	-0.6	-1.5	-1.2	1.2	-0.9	-1.2	-1.6	-0.2	-1.1	-0.2
Arm fat mass (left)	2.4	10.0	17.5	-4.1	-0.7	-4.0	-3.1	-2.8	-2.5	-2.3	-4.2	-4.2	3.9	-3.3	-3.6	-3.3	-2.6	-1.7	-2.0
Number of self-reported non-cancer illnesses	6.7	11.6	18.6	-4.2	-0.6	-3.6	-3.6	-3.3	-2.8	-3.3	-4.1	-4.0	4.1	-4.3	-3.1	-2.8	-3.1	-2.4	-3.3
Average weekly champagne plus white wine intake	0.0	0.1	0.1	-0.3	-0.0	-0.0	0.3	-0.2	0.4	-0.3	-0.2	-0.1	0.4	0.1	0.1	-0.0	-0.3	-0.3	-0.2
Miserableness	0.2	0.4	1.6	-0.2	-0.3	-1.1	-0.1	0.4	-0.9	-1.2	0.0	0.1	0.0	-0.9	-0.1	-1.3	0.8	0.1	0.3
Guilty feelings	1.1	1.7	3.9	-1.6	-1.6	-1.5	-1.1	-0.5	-0.9	-0.6	-1.4	-1.2	1.5	-1.7	-0.4	-1.4	-0.9	-0.9	-2.0
Wears glasses or contact lenses	0.4	0.4	1.7	-0.3	-1.0	-0.7	-0.2	0.4	-1.3	-0.8	-0.4	-0.3	0.1	1.0	-0.7	-0.2	0.1	0.2	1.0
Ever taken oral contraceptive pill	0.4	0.4	1.1	-0.3	0.4	-0.4	-0.9	-0.9	-0.5	-0.4	-0.2	-0.4	0.3	-1.0	-0.5	-0.1	-0.9	-0.8	-1.0
Hearing aid user	0.5	0.6	2.7	0.1	1.6	0.2	0.5	0.9	-0.0	0.7	0.2	-0.0	-0.2	1.2	-0.3	0.1	0.6	0.8	1.6
Mother’s age at death	1.1	1.4	3.4	-1.6	1.3	-0.4	-0.5	-0.8	-0.1	-1.2	-1.5	-1.2	1.7	-1.1	-0.3	-0.4	-1.4	-1.4	-1.8
Financial situation satisfaction	2.0	2.5	6.1	-1.2	-1.2	-1.7	-1.3	-2.5	-1.8	-1.5	-1.1	-1.0	1.1	-1.7	-1.4	-1.4	-1.6	-2.3	-1.8
Tinnitus: Yes, now most or all of the time	3.1	3.6	5.6	2.3	1.4	2.1	1.8	2.2	1.1	2.2	2.0	2.1	-2.3	1.7	1.7	0.8	2.4	1.5	1.8
Commuting to job workplace: Public transport	0.8	0.9	2.6	0.7	0.7	0.9	1.2	1.2	-0.3	1.6	0.8	0.9	-0.8	0.2	1.1	-0.2	1.6	0.8	0.9
Eye problems/disorders: Glaucoma	0.8	1.0	2.1	-1.2	-0.9	-0.8	-0.7	-1.0	-0.2	-1.3	-1.5	-1.2	1.3	-0.7	-0.8	0.1	-1.3	-0.6	-0.9
Medication: Blood pressure	1.3	2.4	5.5	-1.6	-1.1	-1.6	-1.3	-1.2	-2.3	-2.0	-1.4	-1.4	1.4	-1.4	-1.9	-2.2	-1.0	-1.3	-0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.6	-0.8	-0.8	-0.8	0.0	0.3	-0.6	-0.4	-0.6	-0.4	0.7	-0.7	-0.2	-0.8	-0.2	-0.8	-0.7
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.6	0.3	-0.3	0.3	0.7	0.4	-0.0	-0.2	0.6	0.8	-0.3	0.2	0.5	0.3	-0.1	-0.5	-0.3
High cholesterol (Self-reported)	0.1	0.2	1.2	0.1	-0.9	0.1	-0.4	0.4	-0.2	0.3	-0.1	-0.2	-0.2	-0.4	-0.4	-1.1	0.9	-0.3	0.4
Medication: Bendroflumethiazide	0.1	0.2	1.6	-0.1	-0.4	-0.2	-0.3	-0.4	-0.2	1.3	0.3	0.1	0.1	-0.8	0.0	0.1	-0.4	-0.3	-0.6
Medication: Paracetamol	4.1	6.4	8.9	-2.9	-1.1	-2.7	-2.7	-2.9	-2.2	-2.3	-3.0	-3.0	2.8	-2.9	-2.7	-2.6	-2.3	-1.7	-2.0
Medication: Lisinopril	1.7	2.3	6.2	-1.3	-1.6	-2.1	-1.8	-1.0	-1.9	-1.4	-1.4	-1.6	1.2	-1.2	-2.0	-2.5	-0.6	-0.4	-0.3
Medication: Atorvastatin	0.3	0.4	2.9	-0.1	1.7	-0.3	-0.4	0.2	0.2	1.1	-0.2	-0.3	0.1	-0.2	-0.1	0.8	-0.2	0.7	0.2
Illnesses of father: High blood pressure	0.5	0.6	2.4	0.0	0.4	-1.0	-0.9	-0.5	-1.6	-0.8	0.1	-0.3	-0.2	0.2	-1.4	-1.2	-0.1	-0.6	0.5
Alcohol drinker status: Never	0.6	0.7	3.2	-0.9	0.3	-0.6	0.0	-0.6	-1.2	-0.1	-0.8	-0.4	0.9	-0.8	-0.0	-0.2	-0.9	-1.8	-1.5
Ever smoked	1.6	2.8	9.7	-1.7	-1.6	-1.6	-1.4	-1.7	-1.5	-1.7	-1.5	-1.8	1.5	-1.4	-2.1	-3.1	-0.5	-1.4	-0.7
Basal metabolic rate	0.4	2.4	6.9	-2.0	1.1	-2.6	-0.9	-1.0	-1.4	-0.9	-2.0	-1.7	1.8	-1.6	-1.5	-2.0	-0.7	-1.4	-0.7
Leg fat percentage (left)	3.0	10.7	19.2	-4.2	-1.0	-3.6	-3.3	-3.3	-1.9	-2.3	-4.3	-4.4	4.1	-3.7	-3.6	-3.7	-2.6	-1.6	-2.3
Arm fat-free mass (left)	0.2	1.2	4.0	-1.5	1.3	-2.0	-0.6	-0.4	-0.7	-0.2	-1.4	-1.3	1.3	-1.1	-1.2	-1.7	-0.1	-0.7	0.0
Number of operations (self-reported)	0.7	1.0	9.6	-0.4	-3.1	-1.0	-0.1	0.3	-1.4	-1.4	-0.2	-0.2	0.2	0.6	-0.7	-0.7	-0.4	-0.3	-0.1
Average weekly beer plus cider intake	0.3	0.4	1.1	0.6	-1.0	-0.4	-0.4	0.9	-0.8	0.2	0.6	0.4	-0.7	-0.3	-0.1	-1.0	1.0	0.5	0.6
Irritability	0.3	0.5	1.9	-0.7	0.3	-0.8	-0.6	-0.0	-1.4	-0.4	-0.6	-0.6	0.6	-0.8	-0.7	-1.2	0.3	0.6	0.6
Risk taking	0.1	0.2	2.1	0.2	1.4	0.2	0.2	-0.5	-0.0	0.2	0.3	0.1	-0.2	0.6	-0.3	0.2	0.1	-0.2	0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.8	0.3	0.3	0.2	0.5	-0.5	0.2	0.5	0.1	0.3	-0.3	0.6	0.2	0.9	-0.3	-0.8	-0.0
Fractured/broken bones in last 5 years	1.5	1.9	3.4	1.4	0.8	1.3	1.8	1.0	1.6	1.5	1.6	1.7	-1.3	1.2	1.8	1.7	0.8	1.1	0.4
Age started oral contraceptive pill	0.5	0.6	4.9	-0.4	2.2	-0.1	-0.3	0.0	0.1	0.5	-0.5	-0.5	0.5	0.5	-0.7	1.1	-0.8	-0.5	0.3
Diastolic blood pressure, automated reading	2.0	6.1	11.6	-2.4	-2.8	-2.9	-2.7	-2.3	-3.4	-2.9	-2.2	-2.5	2.3	-2.9	-2.9	-2.7	-1.6	-0.5	-0.8
Ever depressed for a whole week	2.7	3.4	7.3	-1.8	0.3	-1.4	-1.3	-2.7	-1.2	-2.3	-1.7	-1.6	1.7	-2.5	-1.5	-2.3	-1.4	-2.2	-2.0
Unable to work because of sickness or disability	0.8	1.0	4.0	-0.4	-2.0	-1.1	-0.8	-0.5	-1.9	-0.9	-0.1	-0.5	0.2	-0.7	-1.0	-1.9	0.3	-0.0	0.1
Commuting to job workplace: Cycle	0.3	0.4	1.5	-0.5	-0.0	-0.6	-0.8	-1.0	-0.3	-0.7	-0.4	-0.4	0.5	-0.1	-0.4	0.8	-1.2	-0.2	-0.5
Myopia	1.0	1.4	4.0	1.5	0.5	1.2	1.1	0.4	2.0	0.4	1.5	1.3	-1.4	1.0	1.4	0.9	1.2	1.3	0.9
Vascular/heart problems diagnosed by doctor	2.2	6.0	11.9	3.0	1.4	3.2	2.6	1.5	3.5	1.9	2.8	3.0	-2.7	2.7	2.8	2.8	1.4	0.5	0.9
Cholesterol lowering medication	0.7	1.0	2.2	-1.4	-0.5	-1.1	-0.7	-0.6	-0.6	-1.0	-1.5	-1.4	1.3	-0.5	-1.2	-1.4	-0.6	-0.9	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.9	0.1	-0.1	-0.7	-1.4	-1.1	-0.4	-0.1	0.2	-0.4	-0.2	0.0	-1.3	-0.0	-0.2	0.2	0.6
Pain experienced in last month	0.3	0.6	1.3	0.8	-0.3	0.6	0.2	-0.1	-1.0	1.1	1.0	0.9	-0.9	0.8	-0.0	1.2	-0.1	0.7	0.9
Supplements: Calcium	0.3	0.3	1.5	-0.0	-1.2	-0.6	-0.7	-0.3	-0.9	-0.4	0.5	0.0	-0.0	-0.4	-0.1	-0.4	-0.4	0.2	-0.5
Basal cell carcinoma (self-reported)	0.2	0.3	1.0	-0.4	0.8	0.4	0.2	-1.0	0.7	-0.8	0.0	-0.3	0.5	-0.4	-0.2	0.2	-0.4	-0.6	-0.4
Heart attack/myocardial infarction (self-reported)	1.9	2.4	5.4	-1.9	-0.7	-1.6	-1.3	-1.1	-1.7	-1.3	-1.5	-1.5	1.8	-1.6	-1.1	-1.4	-1.9	-1.6	-2.3
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.3	1.1	0.5	0.2	0.3	0.7	-0.2	0.4	1.4	1.0	-1.2	0.9	0.1	0.9	0.9	1.1	1.5
Heart disease (siblings)	3.7	4.6	7.6	-2.8	-1.6	-1.9	-1.9	-1.4	-2.3	-1.5	-2.6	-2.5	2.6	-2.4	-2.0	-2.1	-1.9	-1.8	-2.3
Alcohol drinker status: Previous	1.5	1.7	3.5	-1.3	-0.7	-1.6	-1.8	-1.4	-1.0	-1.9	-1.6	-1.7	1.2	-0.6	-1.9	-1.3	-0.8	-0.6	-0.1
Pack years of smoking	4.3	6.2	10.0	-2.7	-0.0	-2.6	-2.4	-2.2	-1.8	-2.6	-2.5	-2.5	2.7	-2.9	-2.2	-2.3	-2.8	-3.0	-3.2
Impedance of whole body	0.3	1.3	11.5	0.9	-3.4	-0.0	-0.5	-0.1	-2.1	-1.0	1.1	0.7	-1.0	0.5	-0.3	-0.4	0.0	0.0	0.3
Leg fat mass (left)	2.6	10.1	17.9	-4.1	-0.6	-4.0	-3.2	-3.0	-2.0	-2.4	-4.2	-4.2	3.9	-3.4	-3.6	-3.6	-2.4	-1.5	-1.9
Arm predicted mass (left)	0.3	1.3	4.6	-1.5	1.3	-2.1	-0.6	-0.5	-0.7	-0.3	-1.4	-1.3	1.3	-1.0	-1.3	-1.7	-0.2	-0.8	-0.1