[Hub]/) : Traits : Height :

chr10:78,845,149-82,223,767

Best TWAS P=7.54e-81 · Best GWAS P=5.57e-76 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLG5 0.10 0.07 lasso 5 0.06 3.3e-08 -10.96 -11.3 2.3e-29 -0.06 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous DLG5 0.39 0.40 lasso 12 0.43 1.9e-38 -10.96 -11.1 8.8e-29 -0.05 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous ZCCHC24 0.12 0.01 lasso 6 0.03 3.4e-03 18.12 19.0 7.5e-81 0.78 0.01 0.95 TRUE
4 GTEx Adipose Subcutaneous RP13-39P12.3 0.31 0.27 lasso 12 0.34 1.1e-28 -11.08 -10.7 8.7e-27 -0.05 0.00 1.00 FALSE
5 GTEx Adipose Visceral Omentum DLG5 0.26 0.23 lasso 8 0.21 5.7e-11 -11.08 -11.2 3.6e-29 -0.05 0.00 1.00 FALSE
6 GTEx Adipose Visceral Omentum BEND3P3 0.27 0.13 lasso 10 0.13 3.0e-07 4.15 -5.2 1.7e-07 -0.02 1.00 0.00 FALSE
7 GTEx Adipose Visceral Omentum RP13-39P12.3 0.18 0.07 lasso 7 0.06 3.3e-04 -11.08 -10.6 4.9e-26 -0.03 0.01 0.99 FALSE
8 GTEx Adrenal Gland DLG5 0.22 0.14 lasso 6 0.11 8.5e-05 -11.08 -11.4 2.4e-30 -0.06 0.01 0.99 FALSE
9 GTEx Artery Aorta DLG5 0.26 0.19 enet 10 0.22 2.6e-12 -10.63 -11.0 3.7e-28 -0.06 0.02 0.98 FALSE
10 GTEx Artery Aorta BEND3P3 0.19 0.05 enet 22 0.09 7.5e-06 3.61 -8.4 5.8e-17 -0.07 0.86 0.04 FALSE
11 GTEx Artery Aorta RP11-119F19.2 0.22 0.16 lasso 9 0.18 2.7e-10 6.71 -6.0 1.8e-09 0.00 1.00 0.00 FALSE
12 GTEx Artery Aorta RP13-39P12.3 0.14 0.13 enet 9 0.12 2.2e-07 -10.63 -10.9 1.0e-27 -0.06 0.02 0.98 FALSE
13 GTEx Artery Coronary DLG5 0.33 0.25 lasso 4 0.27 1.4e-09 -10.88 -11.0 5.2e-28 -0.07 0.01 0.99 FALSE
14 GTEx Artery Coronary RP11-119F19.2 0.24 0.14 lasso 6 0.12 7.0e-05 7.67 -7.0 2.4e-12 -0.02 0.48 0.03 FALSE
15 GTEx Artery Coronary RP13-39P12.3 0.21 0.03 lasso 4 0.09 7.2e-04 -10.88 -10.6 4.6e-26 -0.07 0.02 0.94 FALSE
16 GTEx Artery Tibial DLG5 0.24 0.18 lasso 5 0.18 9.7e-14 -10.91 -10.9 8.2e-28 -0.04 0.00 1.00 FALSE
17 GTEx Artery Tibial BEND3P3 0.22 0.07 enet 14 0.10 5.8e-08 6.71 -7.1 1.7e-12 -0.04 0.97 0.00 FALSE
18 GTEx Artery Tibial RP11-119F19.2 0.20 0.06 enet 26 0.18 7.2e-14 6.64 -6.1 1.1e-09 -0.02 0.99 0.00 FALSE
19 GTEx Artery Tibial RP13-39P12.3 0.14 0.04 lasso 7 0.05 7.3e-05 -10.91 -10.3 5.6e-25 -0.03 0.01 0.99 FALSE
20 GTEx Artery Tibial RP11-506M13.3 0.12 0.06 lasso 5 0.04 3.2e-04 6.71 -7.7 2.0e-14 -0.16 0.44 0.13 FALSE
21 GTEx Brain Cerebellar Hemisphere DLG5 0.48 0.09 lasso 11 0.21 3.8e-06 6.31 -9.5 1.6e-21 -0.07 0.03 0.93 FALSE
22 GTEx Brain Cerebellum DLG5 0.36 0.28 lasso 7 0.36 1.6e-11 -10.96 -10.7 8.8e-27 -0.04 0.01 0.99 FALSE
23 GTEx Brain Cerebellum RP13-39P12.3 0.24 0.14 lasso 10 0.17 1.3e-05 6.71 -9.5 2.6e-21 -0.04 0.07 0.87 FALSE
24 GTEx Breast Mammary Tissue DLG5 0.15 0.09 lasso 7 0.08 6.7e-05 -10.79 -11.0 2.4e-28 -0.07 0.02 0.97 FALSE
25 GTEx Breast Mammary Tissue (Male) POLR3A 0.18 0.02 lasso 1 0.02 9.3e-02 5.80 -5.8 6.5e-09 0.07 0.05 0.09 TRUE
26 GTEx Cells Transformed fibroblasts DLG5 0.25 0.18 lasso 11 0.16 2.0e-12 -10.97 -11.3 1.4e-29 -0.06 0.01 0.99 FALSE
27 GTEx Cells Transformed fibroblasts RP13-39P12.3 0.19 0.13 lasso 7 0.15 4.5e-11 -10.97 -11.1 8.1e-29 -0.05 0.01 0.99 FALSE
28 GTEx Colon Sigmoid DLG5 0.23 0.11 lasso 5 0.15 4.6e-06 6.69 -10.2 1.4e-24 -0.04 0.02 0.94 FALSE
29 GTEx Colon Sigmoid RP13-39P12.3 0.18 0.11 lasso 3 0.10 1.6e-04 6.69 -8.5 2.4e-17 -0.02 0.15 0.70 FALSE
30 GTEx Colon Transverse DLG5 0.23 0.17 lasso 8 0.19 1.4e-09 -10.88 -11.0 6.5e-28 -0.06 0.01 0.98 FALSE
31 GTEx Colon Transverse BEND3P3 0.17 0.07 lasso 4 0.08 8.0e-05 4.79 -5.8 6.7e-09 -0.03 0.42 0.03 TRUE
32 GTEx Colon Transverse RP13-39P12.3 0.20 0.14 lasso 5 0.17 1.6e-08 6.71 -8.5 1.5e-17 -0.04 0.43 0.56 FALSE
33 GTEx Esophagus Gastroesophageal Junction DLG5 0.27 0.03 enet 13 0.06 3.9e-03 -10.89 -9.6 1.3e-21 -0.10 0.01 0.96 FALSE
34 GTEx Esophagus Mucosa DLG5 0.21 0.16 lasso 5 0.18 5.2e-12 -10.96 -10.9 1.6e-27 -0.04 0.01 0.99 FALSE
35 GTEx Esophagus Mucosa BEND3P3 0.12 0.09 enet 20 0.13 7.6e-09 6.64 -5.2 1.9e-07 -0.02 0.95 0.00 FALSE
36 GTEx Esophagus Mucosa RP11-119F19.2 0.20 0.10 lasso 5 0.18 2.1e-12 6.64 -6.3 2.5e-10 0.00 1.00 0.00 FALSE
37 GTEx Esophagus Mucosa RP13-39P12.3 0.12 0.04 lasso 2 0.03 2.9e-03 6.46 -8.8 1.6e-18 -0.04 0.19 0.78 FALSE
38 GTEx Esophagus Muscularis DLG5 0.14 0.04 enet 27 0.06 1.9e-04 6.73 -9.2 3.7e-20 -0.08 0.08 0.88 FALSE
39 GTEx Esophagus Muscularis RP13-39P12.3 0.10 0.04 lasso 8 0.02 1.6e-02 6.69 -6.9 3.8e-12 -0.02 0.27 0.26 FALSE
40 GTEx Heart Atrial Appendage DLG5 0.32 0.23 lasso 4 0.24 3.9e-11 -10.79 -11.0 3.1e-28 -0.06 0.01 0.99 FALSE
41 GTEx Heart Atrial Appendage BEND3P3 0.20 0.13 enet 14 0.13 2.1e-06 6.67 -5.8 8.8e-09 -0.01 0.63 0.02 TRUE
42 GTEx Heart Atrial Appendage RP11-119F19.2 0.18 0.03 lasso 7 0.05 2.5e-03 6.64 -7.2 5.5e-13 0.03 0.14 0.04 FALSE
43 GTEx Heart Atrial Appendage RP13-39P12.3 0.22 0.11 lasso 4 0.16 7.7e-08 6.69 -9.9 2.6e-23 -0.04 0.03 0.96 FALSE
44 GTEx Heart Left Ventricle DLG5 0.13 0.10 lasso 4 0.09 1.2e-05 -10.79 -11.0 6.5e-28 -0.06 0.01 0.99 FALSE
45 GTEx Liver DLG5 0.42 0.31 lasso 5 0.28 2.1e-08 -10.97 -10.8 4.9e-27 -0.06 0.01 0.99 FALSE
46 GTEx Liver RP13-39P12.3 0.29 0.03 enet 21 0.07 4.6e-03 -10.97 -8.9 4.1e-19 -0.07 0.01 0.93 FALSE
47 GTEx Lung DLG5 0.41 0.38 lasso 8 0.37 7.9e-30 -11.08 -11.1 7.4e-29 -0.05 0.00 1.00 FALSE
48 GTEx Lung BEND3P3 0.16 0.06 enet 12 0.09 2.7e-07 3.98 -5.8 8.4e-09 0.00 0.87 0.01 FALSE
49 GTEx Lung RP11-119F19.2 0.24 0.09 lasso 12 0.18 1.5e-13 4.16 -6.0 2.0e-09 -0.03 1.00 0.00 FALSE
50 GTEx Lung RP13-39P12.3 0.36 0.28 enet 27 0.31 2.5e-24 -11.08 -10.5 1.1e-25 -0.06 0.00 1.00 FALSE
51 GTEx Muscle Skeletal RP11-119F19.2 0.12 0.03 lasso 7 0.06 2.3e-06 -3.22 -5.2 1.9e-07 -0.03 0.92 0.01 FALSE
52 GTEx Nerve Tibial DLG5 0.51 0.44 lasso 6 0.50 1.4e-39 -10.91 -11.5 8.8e-31 -0.06 0.01 0.99 TRUE
53 GTEx Nerve Tibial BEND3P3 0.16 0.07 enet 16 0.13 1.8e-09 4.02 -5.9 3.4e-09 -0.02 0.99 0.00 FALSE
54 GTEx Nerve Tibial RP11-119F19.2 0.18 0.11 enet 25 0.12 7.0e-09 4.07 -5.9 3.7e-09 -0.01 0.93 0.00 FALSE
55 GTEx Nerve Tibial RP13-39P12.3 0.31 0.25 lasso 7 0.36 1.3e-26 -11.08 -11.0 4.4e-28 -0.06 0.00 1.00 FALSE
56 GTEx Ovary DLG5 0.62 0.38 lasso 6 0.40 5.3e-11 -10.97 -11.5 1.5e-30 -0.04 0.01 0.99 FALSE
57 GTEx Ovary BEND3P3 0.27 0.09 enet 24 0.09 3.1e-03 2.10 -6.9 5.0e-12 -0.17 0.07 0.11 FALSE
58 GTEx Ovary RP13-39P12.3 0.42 0.29 lasso 5 0.33 7.5e-09 -10.97 -11.3 8.6e-30 -0.04 0.01 0.98 FALSE
59 GTEx Pancreas DLG5 0.39 0.43 enet 11 0.44 3.5e-20 -10.91 -11.1 1.7e-28 -0.05 0.01 0.99 FALSE
60 GTEx Pancreas RP13-39P12.3 0.20 0.24 lasso 3 0.23 3.8e-10 -11.08 -11.1 1.8e-28 -0.05 0.00 1.00 FALSE
61 GTEx Pituitary DLG5 0.45 0.36 lasso 11 0.31 1.9e-08 -10.97 -11.3 1.4e-29 -0.06 0.01 0.99 FALSE
62 GTEx Pituitary RP13-39P12.3 0.38 0.22 lasso 11 0.17 3.8e-05 -10.97 -11.4 6.3e-30 -0.06 0.02 0.96 FALSE
63 GTEx Skin Not Sun Exposed Suprapubic DLG5 0.18 0.01 enet 24 0.13 2.0e-07 -9.24 -8.3 1.1e-16 -0.02 0.01 0.97 FALSE
64 GTEx Skin Not Sun Exposed Suprapubic RP11-119F19.2 0.24 0.13 enet 11 0.20 5.1e-11 3.98 -5.7 1.6e-08 -0.01 0.99 0.00 FALSE
65 GTEx Skin Not Sun Exposed Suprapubic RP13-39P12.3 0.15 0.10 enet 22 0.11 1.2e-06 6.69 -6.2 5.0e-10 0.00 0.37 0.24 FALSE
66 GTEx Skin Sun Exposed Lower leg DLG5 0.12 0.06 lasso 4 0.06 4.9e-06 -11.08 -11.2 5.9e-29 -0.04 0.00 0.99 FALSE
67 GTEx Skin Sun Exposed Lower leg ZCCHC24 0.09 0.00 enet 18 0.00 2.3e-01 -0.42 13.5 1.1e-41 0.43 0.02 0.63 FALSE
68 GTEx Skin Sun Exposed Lower leg RP13-39P12.3 0.11 0.06 lasso 2 0.05 3.7e-05 6.69 -6.8 1.3e-11 0.00 0.26 0.38 FALSE
69 GTEx Skin Sun Exposed Lower leg RP11-342M3.5 0.08 0.00 enet 28 0.01 7.3e-02 0.32 10.6 2.3e-26 0.30 0.04 0.27 TRUE
70 GTEx Spleen DLG5 0.51 0.46 lasso 4 0.44 1.1e-12 -10.91 -11.0 5.4e-28 -0.04 0.01 0.99 FALSE
71 GTEx Spleen RP13-39P12.3 0.38 0.34 lasso 2 0.35 8.8e-10 -10.91 -10.9 8.6e-28 -0.04 0.01 0.99 FALSE
72 GTEx Stomach DLG5 0.20 0.12 lasso 7 0.08 1.3e-04 -10.91 -11.0 3.8e-28 -0.04 0.01 0.99 FALSE
73 GTEx Stomach RP13-39P12.3 0.17 0.02 lasso 5 0.02 2.5e-02 6.69 -9.9 3.0e-23 -0.02 0.02 0.89 FALSE
74 GTEx Thyroid DLG5 0.39 0.43 lasso 5 0.43 1.5e-35 -11.08 -11.1 1.9e-28 -0.05 0.00 1.00 FALSE
75 GTEx Thyroid RP11-119F19.2 0.24 0.09 lasso 6 0.17 7.2e-13 3.98 -6.8 1.3e-11 -0.01 1.00 0.00 FALSE
76 GTEx Thyroid RP13-39P12.3 0.28 0.30 lasso 8 0.29 3.3e-22 -11.08 -11.1 8.1e-29 -0.05 0.00 1.00 FALSE
77 GTEx Whole Blood DLG5 0.10 0.06 lasso 9 0.10 2.3e-09 6.56 -10.1 5.5e-24 -0.04 0.07 0.93 FALSE
78 GTEx Whole Blood RP13-39P12.3 0.11 0.12 lasso 6 0.12 8.1e-11 6.56 -6.7 2.3e-11 -0.03 1.00 0.00 FALSE
79 METSIM Adipose DLG5 0.18 0.19 lasso 11 0.22 2.2e-32 -11.08 -10.8 2.6e-27 -0.04 0.00 1.00 FALSE
80 ROSMAP Brain Pre-frontal Cortex PPIF 0.05 0.01 lasso 4 0.02 2.9e-03 -5.82 7.5 8.9e-14 0.29 0.34 0.22 TRUE
81 ROSMAP Brain Pre-frontal Cortex DLG5 0.19 0.17 bslmm 592 0.20 1.5e-24 -10.97 -11.0 2.9e-28 -0.05 0.01 0.99 FALSE
82 ROSMAP Brain Pre-frontal Cortex SFTPA2 0.22 0.16 bslmm 349 0.20 2.3e-25 4.80 -5.6 2.5e-08 -0.03 1.00 0.00 FALSE
83 ROSMAP Brain Pre-frontal Cortex NUTM2B 0.19 0.11 enet 19 0.16 1.1e-20 4.07 -5.6 2.2e-08 0.03 1.00 0.00 FALSE
84 YFS Blood DLG5 0.04 0.03 bslmm 583 0.03 2.8e-10 6.36 -7.5 5.3e-14 -0.04 1.00 0.00 FALSE
85 The Cancer Genome Atlas Bladder Urothelial Carcinoma DLG5 0.08 0.00 blup 116 0.02 4.0e-03 -10.79 -9.2 3.1e-20 -0.02 0.01 0.87 FALSE
86 The Cancer Genome Atlas Bladder Urothelial Carcinoma ZCCHC24 0.06 0.00 blup 89 0.01 6.2e-02 4.67 13.6 2.1e-42 0.41 0.01 0.07 FALSE
87 The Cancer Genome Atlas Breast Invasive Carcinoma DLG5 0.02 0.01 enet 9 0.01 3.5e-03 4.42 -7.4 1.3e-13 -0.06 0.10 0.65 FALSE
88 The Cancer Genome Atlas Breast Invasive Carcinoma SFTPA2 0.06 0.03 enet 12 0.04 2.1e-09 3.61 -5.3 1.0e-07 0.00 0.21 0.79 TRUE
89 The Cancer Genome Atlas Breast Invasive Carcinoma ZCCHC24 0.03 0.01 blup 89 0.02 2.0e-04 4.79 6.7 2.2e-11 0.17 0.40 0.02 TRUE
90 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DLG5 0.12 0.01 blup 116 0.03 1.2e-02 -10.88 -10.1 5.5e-24 -0.05 0.02 0.68 FALSE
91 The Cancer Genome Atlas Colon Adenocarcinoma DLG5 0.08 0.03 blup 116 0.06 2.1e-04 4.19 -8.3 1.3e-16 -0.06 0.06 0.92 FALSE
92 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZCCHC24 0.07 0.05 enet 9 0.04 6.7e-05 16.95 17.4 1.0e-67 0.95 0.00 1.00 TRUE
93 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DLG5 0.09 0.05 blup 116 0.07 4.5e-05 6.30 -9.6 1.3e-21 -0.04 0.08 0.90 FALSE
94 The Cancer Genome Atlas Brain Lower Grade Glioma DLG5 0.03 0.01 blup 116 0.02 6.9e-03 6.69 -9.7 2.7e-22 -0.03 0.03 0.69 FALSE
95 The Cancer Genome Atlas Brain Lower Grade Glioma SFTPA2 0.14 0.08 enet 8 0.10 7.6e-12 4.16 -5.5 3.0e-08 0.00 0.02 0.98 FALSE
96 The Cancer Genome Atlas Lung Adenocarcinoma DLG5 0.03 0.01 blup 116 0.02 3.1e-03 6.69 -9.3 1.4e-20 -0.03 0.07 0.66 FALSE
97 The Cancer Genome Atlas Pancreatic Adenocarcinoma DLG5 0.15 0.00 blup 116 0.07 6.3e-04 -10.79 -10.4 2.0e-25 -0.07 0.01 0.97 FALSE
98 The Cancer Genome Atlas Prostate Adenocarcinoma DLG5 0.10 0.05 blup 116 0.05 2.1e-06 -11.07 -9.2 2.5e-20 -0.04 0.01 0.99 FALSE
99 The Cancer Genome Atlas Thyroid Carcinoma DLG5 0.13 0.08 enet 10 0.10 1.2e-09 -10.16 -10.5 6.7e-26 -0.05 0.03 0.97 FALSE