[Hub]/) : Traits : Height :

chr11:84,642,072-86,688,920

Best TWAS P=5.69e-17 · Best GWAS P=8.84e-18 conditioned to 0.0319

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TMEM126B 0.03 0.02 bslmm 349 0.02 8.1e-04 6.7 -5.5 4.3e-08 0.52 0.45 0.08 FALSE
2 GTEx Artery Aorta TMEM126A 0.13 0.11 lasso 7 0.13 1.4e-07 -6.7 5.6 2.6e-08 -0.42 0.92 0.01 FALSE
3 GTEx Artery Tibial SYTL2 0.08 0.00 enet 17 0.00 4.2e-01 -6.1 6.2 4.4e-10 -0.51 0.16 0.04 FALSE
4 GTEx Cells Transformed fibroblasts SYTL2 0.14 0.03 lasso 5 0.05 1.1e-04 -8.6 8.4 5.7e-17 -0.94 0.01 0.99 TRUE
5 GTEx Cells Transformed fibroblasts CCDC89 0.06 0.07 lasso 4 0.05 8.3e-05 -7.2 -6.7 1.7e-11 0.76 0.45 0.40 FALSE
6 GTEx Muscle Skeletal SYTL2 0.10 0.11 lasso 5 0.10 2.2e-10 -6.8 7.6 3.0e-14 -0.80 0.86 0.14 FALSE
7 GTEx Nerve Tibial SYTL2 0.05 0.03 enet 9 0.02 2.4e-02 -7.9 7.7 1.1e-14 -0.90 0.02 0.96 FALSE
8 METSIM Adipose PICALM 0.06 0.04 enet 26 0.05 1.7e-07 -4.8 -5.5 4.5e-08 0.51 0.94 0.06 FALSE
9 NTR Blood PICALM 0.02 0.01 blup 501 0.01 3.2e-05 -5.2 -5.6 1.8e-08 0.46 0.96 0.01 FALSE
10 YFS Blood EED 0.07 0.09 enet 16 0.09 4.1e-27 -5.7 -5.9 4.6e-09 -0.05 1.00 0.00 TRUE
11 YFS Blood SYTL2 0.36 0.27 bslmm 411 0.32 2.1e-107 -7.4 6.7 2.1e-11 -0.76 0.93 0.07 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SYTL2 0.04 0.03 lasso 4 0.03 1.9e-04 -7.9 8.0 8.7e-16 -0.90 0.02 0.98 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma C11orf73 0.04 0.00 blup 65 0.01 4.9e-02 4.2 -5.5 3.1e-08 -0.05 0.01 0.51 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma PICALM 0.04 0.01 blup 87 0.02 1.9e-03 4.7 6.0 2.1e-09 -0.29 0.04 0.76 TRUE
15 The Cancer Genome Atlas Lung Adenocarcinoma SYTL2 0.01 0.03 lasso 3 0.02 6.3e-04 -7.5 7.5 4.8e-14 -0.79 0.08 0.61 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC83 0.06 0.00 blup 79 0.03 4.0e-04 -3.1 -7.5 9.2e-14 0.60 0.01 0.33 FALSE