[Hub]/) : Traits : Height :

chr12:52,761,469-54,593,953

Best TWAS P=1.94e-12 · Best GWAS P=2.2e-21 conditioned to 1.36e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta PRR13 0.23 0.28 enet 39 0.30 4.3e-17 2.4 -5.3 9.5e-08 -0.02 1.00 0.00 FALSE
2 GTEx Artery Coronary SP1 0.17 0.12 lasso 4 0.12 8.6e-05 4.8 7.0 3.4e-12 0.23 0.20 0.51 FALSE
3 GTEx Brain Hippocampus AAAS 0.32 0.04 enet 23 0.04 4.6e-02 -4.3 -7.0 3.3e-12 -0.08 0.08 0.08 TRUE
4 GTEx Breast Mammary Tissue SP1 0.12 0.13 lasso 5 0.08 9.5e-05 4.0 6.1 8.3e-10 0.17 0.77 0.18 TRUE
5 GTEx Heart Left Ventricle RP11-793H13.11 0.12 0.00 enet 17 0.05 1.6e-03 -4.2 5.6 1.8e-08 0.05 0.25 0.12 TRUE
6 GTEx Thyroid PRR13 0.22 0.18 lasso 9 0.24 4.8e-18 4.7 -5.1 2.9e-07 0.00 1.00 0.00 FALSE
7 METSIM Adipose SOAT2 0.03 0.06 lasso 1 0.05 1.5e-08 5.7 -5.7 1.3e-08 -0.36 1.00 0.00 FALSE
8 METSIM Adipose SP7 0.03 0.02 lasso 2 0.01 6.1e-03 5.7 -7.0 1.9e-12 -0.47 0.23 0.09 TRUE
9 METSIM Adipose SPRYD3 0.15 0.06 lasso 10 0.05 8.8e-08 4.7 6.5 9.7e-11 0.69 0.03 0.97 FALSE
10 YFS Blood SP1 0.22 0.17 bslmm 398 0.18 1.4e-56 4.9 5.3 1.1e-07 0.06 1.00 0.00 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRR13 0.13 0.04 blup 28 0.07 3.3e-06 4.8 -6.1 8.3e-10 -0.03 0.08 0.34 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PRR13 0.03 0.03 blup 28 0.04 4.6e-05 4.7 -5.4 6.6e-08 0.01 0.44 0.09 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PRR13 0.08 0.05 blup 28 0.07 6.3e-08 4.6 -5.5 3.0e-08 -0.01 0.96 0.03 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma PRR13 0.07 0.04 blup 28 0.05 4.7e-06 2.4 -5.7 1.2e-08 -0.04 0.48 0.06 FALSE