Best TWAS P=8.72e-26 · Best GWAS P=4.77e-26 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | KIAA1614 | 0.19 | 0.17 | lasso | 7 | 0.18 | 2.9e-21 | 10.6 | -10.5 | 8.7e-26 | -0.97 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Brain Cerebellum | XPR1 | 0.27 | -0.01 | enet | 19 | 0.06 | 6.4e-03 | 4.4 | 6.9 | 6.2e-12 | 0.19 | 0.22 | 0.06 | TRUE |
| 3 | METSIM | Adipose | KIAA1614 | 0.06 | 0.04 | bslmm | 452 | 0.03 | 6.5e-06 | -7.5 | -7.3 | 2.0e-13 | -0.57 | 0.09 | 0.90 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | KIAA1614 | 0.14 | 0.05 | enet | 11 | 0.07 | 9.9e-09 | -7.7 | -6.9 | 5.9e-12 | -0.54 | 0.04 | 0.93 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | KIAA1614 | 0.25 | 0.08 | lasso | 3 | 0.07 | 3.6e-07 | 10.6 | -10.1 | 5.3e-24 | -0.94 | 0.00 | 1.00 | FALSE |