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chr16:74,485,529-76,197,034

Best TWAS P=9.53e-23 · Best GWAS P=4.81e-22 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CFDP1	0.08	0.04	lasso	4	0.04	1.6e-05	-7.6	-7.4	1.4e-13	0.14	0.98	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CFDP1	0.11	0.09	lasso	2	0.09	1.1e-07	-6.3	-6.3	3.7e-10	0.11	0.99	0.00	FALSE
3	GTEx	Adipose Subcutaneous	TMEM170A	0.11	0.00	lasso	5	0.01	6.7e-02	-4.7	-5.6	2.2e-08	0.11	0.26	0.04	FALSE
4	GTEx	Adipose Visceral Omentum	CFDP1	0.20	0.09	lasso	4	0.08	5.2e-05	-6.2	-7.0	3.6e-12	0.16	0.55	0.02	FALSE
5	GTEx	Adipose Visceral Omentum	ZFP1	0.38	0.21	lasso	5	0.21	5.6e-11	-9.3	8.9	7.3e-19	-0.73	0.03	0.97	FALSE
6	GTEx	Adrenal Gland	TMEM170A	0.11	0.06	enet	4	0.04	1.7e-02	-7.8	7.8	8.2e-15	-0.18	0.27	0.04	FALSE
7	GTEx	Adrenal Gland	ZFP1	0.53	0.28	enet	30	0.30	1.7e-11	-9.3	9.2	5.1e-20	-0.69	0.02	0.98	FALSE
8	GTEx	Artery Aorta	BCAR1	0.18	0.13	lasso	3	0.11	9.8e-07	-7.8	8.0	1.9e-15	-0.17	0.99	0.00	FALSE
9	GTEx	Artery Aorta	ZFP1	0.28	0.14	enet	13	0.19	1.0e-10	-9.5	9.4	3.7e-21	-0.83	0.01	0.99	FALSE
10	GTEx	Artery Tibial	BCAR1	0.07	0.06	lasso	1	0.04	2.4e-04	-7.3	7.3	3.1e-13	-0.18	0.59	0.02	FALSE
11	GTEx	Brain Cerebellum	CFDP1	0.25	-0.01	lasso	2	0.05	1.7e-02	-7.8	-6.9	5.1e-12	0.16	0.20	0.04	FALSE
12	GTEx	Brain Cortex	CFDP1	0.18	0.07	lasso	3	0.08	3.4e-03	-6.2	-7.0	2.7e-12	0.12	0.16	0.05	FALSE
13	GTEx	Breast Mammary Tissue	ZFP1	0.21	0.18	lasso	2	0.17	7.0e-09	-9.3	9.8	9.5e-23	-0.84	0.02	0.98	TRUE
14	GTEx	Breast Mammary Tissue (Male)	ZFP1	0.23	0.24	lasso	3	0.22	7.8e-06	-9.4	9.3	1.3e-20	-0.94	0.01	0.97	TRUE
15	GTEx	Breast Mammary Tissue (Female)	CFDP1	0.07	0.05	lasso	1	0.05	1.5e-02	-6.3	-6.3	3.2e-10	0.10	0.09	0.05	FALSE
16	GTEx	Cells EBV-transformed lymphocytes	TMEM170A	0.13	0.07	lasso	3	0.02	6.2e-02	-5.9	-6.1	8.4e-10	0.21	0.15	0.05	FALSE
17	GTEx	Cells Transformed fibroblasts	CFDP1	0.17	0.20	enet	10	0.24	9.9e-18	-7.8	-8.1	4.4e-16	0.14	1.00	0.00	FALSE
18	GTEx	Cells Transformed fibroblasts	ZFP1	0.47	0.29	enet	28	0.33	1.6e-25	-9.3	5.7	1.6e-08	-0.56	0.04	0.96	FALSE
19	GTEx	Colon Transverse	CFDP1	0.14	0.11	lasso	2	0.08	7.6e-05	-6.2	-5.7	1.0e-08	0.09	0.56	0.02	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	CFDP1	0.31	0.17	lasso	4	0.16	3.0e-06	-6.5	-6.5	5.8e-11	0.10	0.89	0.01	FALSE
21	GTEx	Esophagus Gastroesophageal Junction	ZFP1	0.35	0.16	lasso	3	0.14	7.7e-06	-9.3	7.2	6.9e-13	-0.53	0.02	0.95	FALSE
22	GTEx	Esophagus Mucosa	BCAR1	0.16	0.13	lasso	8	0.14	1.8e-09	-7.6	-7.3	3.2e-13	0.20	1.00	0.00	FALSE
23	GTEx	Esophagus Muscularis	CFDP1	0.18	0.12	lasso	5	0.09	3.1e-06	-6.2	-6.1	1.4e-09	0.10	0.99	0.00	FALSE
24	GTEx	Esophagus Muscularis	ZFP1	0.30	0.23	lasso	4	0.26	3.8e-16	-9.3	6.9	5.9e-12	-0.50	0.02	0.98	FALSE
25	GTEx	Heart Atrial Appendage	ZFP1	0.23	0.15	lasso	2	0.14	9.1e-07	-9.3	9.3	2.1e-20	-0.74	0.02	0.97	FALSE
26	GTEx	Heart Left Ventricle	ZFP1	0.37	0.20	lasso	8	0.19	1.4e-10	-9.3	8.3	1.1e-16	-0.76	0.02	0.98	FALSE
27	GTEx	Lung	ZFP1	0.22	0.10	lasso	6	0.13	3.2e-10	-9.3	6.8	1.4e-11	-0.67	0.03	0.97	TRUE
28	GTEx	Muscle Skeletal	CFDP1	0.05	0.05	enet	4	0.04	3.4e-05	-6.0	-6.2	5.9e-10	0.10	0.90	0.00	FALSE
29	GTEx	Muscle Skeletal	ZFP1	0.27	0.08	enet	31	0.11	3.1e-11	-9.3	7.4	1.4e-13	-0.73	0.02	0.98	FALSE
30	GTEx	Nerve Tibial	CFDP1	0.16	0.14	lasso	3	0.12	1.6e-08	-6.3	-7.1	9.8e-13	0.14	1.00	0.00	FALSE
31	GTEx	Nerve Tibial	TMEM170A	0.12	0.09	enet	7	0.11	4.1e-08	-3.8	-5.8	4.9e-09	0.11	1.00	0.00	FALSE
32	GTEx	Nerve Tibial	ZFP1	0.41	0.23	enet	17	0.25	8.6e-18	-9.3	7.9	2.4e-15	-0.70	0.02	0.98	FALSE
33	GTEx	Pancreas	CFDP1	0.16	0.07	lasso	2	0.12	1.2e-05	-6.3	-6.5	6.0e-11	0.06	0.55	0.04	FALSE
34	GTEx	Skin Not Sun Exposed Suprapubic	TMEM170A	0.09	0.02	lasso	3	0.05	1.1e-03	-4.8	5.4	5.2e-08	-0.16	0.41	0.02	FALSE
35	GTEx	Skin Not Sun Exposed Suprapubic	ZFP1	0.33	0.15	lasso	10	0.16	2.8e-09	-9.5	8.3	1.1e-16	-0.69	0.02	0.98	FALSE
36	GTEx	Skin Sun Exposed Lower leg	CFDP1	0.17	0.13	enet	25	0.11	2.8e-09	-6.3	-8.4	4.3e-17	0.31	1.00	0.00	TRUE
37	GTEx	Skin Sun Exposed Lower leg	TMEM170A	0.13	0.08	lasso	5	0.06	1.2e-05	-5.9	5.3	8.7e-08	-0.17	0.92	0.00	FALSE
38	GTEx	Testis	ZFP1	0.17	0.14	lasso	3	0.12	4.5e-06	-9.5	9.5	1.8e-21	-0.75	0.01	0.98	FALSE
39	GTEx	Thyroid	ZFP1	0.27	0.16	enet	17	0.18	1.3e-13	-9.3	8.3	1.3e-16	-0.74	0.02	0.98	FALSE
40	METSIM	Adipose	TMEM170A	0.03	0.01	lasso	3	0.02	1.5e-03	-7.9	-7.2	5.0e-13	0.09	0.84	0.03	FALSE
41	YFS	Blood	CFDP1	0.21	0.26	bslmm	396	0.30	1.5e-99	-6.2	-5.5	4.1e-08	0.09	1.00	0.00	FALSE
42	YFS	Blood	ZFP1	0.15	0.08	enet	36	0.08	2.0e-25	-9.3	7.3	2.1e-13	-0.64	0.04	0.96	FALSE
43	The Cancer Genome Atlas	Breast Invasive Carcinoma	CFDP1	0.04	0.03	enet	10	0.03	5.2e-07	-6.3	-6.1	8.1e-10	0.16	1.00	0.00	FALSE
44	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZFP1	0.08	0.10	lasso	3	0.10	2.5e-20	-9.3	9.4	4.4e-21	-0.74	0.02	0.98	FALSE
45	The Cancer Genome Atlas	Colon Adenocarcinoma	CFDP1	0.10	0.04	blup	71	0.06	1.8e-04	-6.0	-5.8	5.1e-09	0.09	0.29	0.21	FALSE
46	The Cancer Genome Atlas	Colon Adenocarcinoma	ZFP1	0.22	0.09	lasso	6	0.12	3.3e-07	-9.5	8.7	3.4e-18	-0.82	0.01	0.99	FALSE
47	The Cancer Genome Atlas	Esophageal Carcinoma	ZFP1	0.19	0.01	blup	63	0.06	6.9e-03	-4.0	6.6	3.5e-11	-0.54	0.01	0.42	FALSE
48	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CFDP1	0.02	0.02	lasso	4	0.02	1.9e-03	-7.8	-7.7	1.9e-14	0.13	0.12	0.40	FALSE
49	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZFP1	0.21	0.12	lasso	5	0.18	2.1e-20	-9.3	8.1	7.6e-16	-0.79	0.02	0.98	FALSE
50	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TMEM170A	0.08	0.10	blup	36	0.13	9.1e-08	-5.9	-7.6	3.7e-14	0.21	0.01	0.99	FALSE
51	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ZFP1	0.17	0.08	blup	62	0.08	3.0e-05	-9.7	5.7	1.3e-08	-0.70	0.00	0.99	FALSE
52	The Cancer Genome Atlas	Brain Lower Grade Glioma	CFDP1	0.04	0.02	lasso	6	0.03	4.0e-04	-6.2	-7.7	1.7e-14	0.13	0.20	0.73	FALSE
53	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZFP1	0.15	0.12	lasso	6	0.13	2.7e-14	-9.7	9.6	6.4e-22	-0.96	0.00	1.00	FALSE
54	The Cancer Genome Atlas	Lung Adenocarcinoma	CFDP1	0.05	0.02	enet	11	0.04	2.0e-05	-6.5	-5.4	8.6e-08	0.14	0.33	0.04	TRUE
55	The Cancer Genome Atlas	Lung Adenocarcinoma	ZFP1	0.20	0.07	enet	11	0.14	1.3e-16	-9.3	8.0	1.1e-15	-0.72	0.03	0.97	TRUE
56	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CFDP1	0.06	0.03	lasso	3	0.03	1.1e-04	-4.2	-5.1	3.1e-07	0.12	0.53	0.02	FALSE
57	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZFP1	0.08	0.05	enet	11	0.05	1.0e-06	-9.5	6.0	1.4e-09	-0.56	0.01	0.99	FALSE
58	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ZFP1	0.37	0.16	blup	63	0.27	1.3e-11	-9.3	6.2	4.0e-10	-0.62	0.02	0.98	FALSE
59	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CFDP1	0.23	0.00	blup	70	0.02	4.2e-02	-6.5	-5.6	2.3e-08	0.04	0.03	0.09	FALSE
60	The Cancer Genome Atlas	Prostate Adenocarcinoma	CFDP1	0.06	0.05	enet	6	0.05	3.2e-06	-6.3	-5.4	6.1e-08	0.08	0.97	0.00	FALSE
61	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZFP1	0.10	0.09	blup	63	0.08	2.2e-08	-9.3	8.1	7.8e-16	-0.63	0.02	0.98	FALSE
62	The Cancer Genome Atlas	Stomach Adenocarcinoma	ZFP1	0.09	0.03	lasso	4	0.05	1.4e-04	-9.3	6.1	8.6e-10	-0.43	0.03	0.92	FALSE
63	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CFDP1	0.10	0.00	blup	70	0.04	1.4e-02	-7.8	-7.3	2.2e-13	0.13	0.03	0.17	FALSE
64	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CHST6	0.20	0.08	enet	10	0.10	2.2e-04	-6.4	7.3	3.6e-13	-0.18	0.01	0.89	FALSE
65	The Cancer Genome Atlas	Thyroid Carcinoma	ZFP1	0.25	0.16	blup	63	0.16	1.5e-15	-9.3	7.2	6.3e-13	-0.61	0.05	0.95	FALSE
66	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	ZFP1	0.32	-0.01	blup	63	0.01	1.6e-01	-9.7	7.8	8.4e-15	-0.75	0.00	0.62	FALSE