Best TWAS P=3.65e-10 · Best GWAS P=1.1e-09 conditioned to 3.36e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | RP11-810M2.2 | 0.30 | 0.02 | lasso | 4 | 0.02 | 8.5e-02 | 5.4 | 6.3 | 3.6e-10 | -0.26 | 0.04 | 0.55 | TRUE |
2 | METSIM | Adipose | CYB5D2 | 0.08 | 0.05 | lasso | 9 | 0.05 | 3.5e-08 | -5.0 | -5.2 | 2.3e-07 | 0.82 | 0.02 | 0.98 | FALSE |