[Hub]/) : Traits : Height :

chr1:217,760,821-221,753,645

Best TWAS P=5.24e-64 · Best GWAS P=8.96e-102 conditioned to 2.14e-57

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC643723 0.12 0.08 blup 517 0.08 1.1e-09 4.9 -5.5 3.7e-08 0.01 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex LYPLAL1 0.04 0.05 lasso 3 0.03 3.6e-04 5.5 -5.9 2.8e-09 0.09 0.61 0.02 FALSE
3 CommonMind Brain Pre-frontal Cortex RRP15 0.55 0.46 enet 22 0.52 9.0e-74 9.4 10.2 1.6e-24 -0.04 1.00 0.00 FALSE
4 GTEx Adipose Subcutaneous RRP15 0.24 0.14 lasso 2 0.12 3.2e-10 9.0 9.1 6.1e-20 -0.06 1.00 0.00 FALSE
5 GTEx Adipose Subcutaneous RP11-295M18.6 0.35 0.24 lasso 6 0.37 5.5e-32 -2.7 -5.2 2.4e-07 -0.09 1.00 0.00 FALSE
6 GTEx Adipose Visceral Omentum RRP15 0.32 0.18 lasso 8 0.22 1.2e-11 9.3 6.8 7.4e-12 -0.08 1.00 0.00 FALSE
7 GTEx Adipose Visceral Omentum RP11-295M18.6 0.32 0.20 enet 10 0.29 2.1e-15 -2.7 -6.5 6.8e-11 -0.06 1.00 0.00 TRUE
8 GTEx Adrenal Gland RRP15 0.41 0.16 enet 30 0.12 5.6e-05 9.0 8.5 2.6e-17 -0.04 0.85 0.01 FALSE
9 GTEx Artery Aorta RRP15 0.23 0.17 lasso 3 0.15 8.3e-09 9.0 8.7 2.5e-18 -0.08 1.00 0.00 FALSE
10 GTEx Artery Tibial RRP15 0.19 0.16 lasso 4 0.14 8.7e-11 9.4 9.4 5.8e-21 -0.06 1.00 0.00 FALSE
11 GTEx Artery Tibial HLA-AS1 0.12 0.03 enet 13 0.05 3.9e-05 5.9 -8.7 2.3e-18 -0.03 0.18 0.72 FALSE
12 GTEx Brain Nucleus accumbens basal ganglia RRP15 0.34 0.25 lasso 4 0.22 1.9e-06 9.4 9.9 6.0e-23 -0.04 0.47 0.04 FALSE
13 GTEx Cells Transformed fibroblasts RRP15 0.38 0.28 lasso 6 0.28 1.9e-21 9.4 9.3 1.8e-20 -0.07 1.00 0.00 FALSE
14 GTEx Cells Transformed fibroblasts HLX 0.06 0.00 enet 9 0.00 5.3e-01 -2.9 -9.1 6.6e-20 0.03 0.02 0.71 TRUE
15 GTEx Cells Transformed fibroblasts HLA-AS1 0.10 0.03 lasso 7 0.04 8.9e-04 5.9 -7.8 8.3e-15 -0.10 0.15 0.52 FALSE
16 GTEx Cells Transformed fibroblasts RP11-295M18.6 0.40 0.28 lasso 8 0.33 2.5e-25 -2.7 -5.7 1.2e-08 -0.08 1.00 0.00 FALSE
17 GTEx Esophagus Mucosa RRP15 0.38 0.29 lasso 6 0.31 3.3e-21 9.0 9.7 2.3e-22 -0.06 1.00 0.00 FALSE
18 GTEx Esophagus Mucosa RP11-295M18.6 0.29 0.12 lasso 9 0.18 4.9e-12 -2.7 -5.6 1.8e-08 -0.11 1.00 0.00 FALSE
19 GTEx Esophagus Muscularis RRP15 0.22 0.23 enet 8 0.22 8.9e-14 9.4 9.1 7.3e-20 -0.02 1.00 0.00 FALSE
20 GTEx Lung RRP15 0.11 0.13 enet 21 0.13 2.6e-10 9.4 9.7 4.6e-22 -0.03 1.00 0.00 FALSE
21 GTEx Lung TGFB2 0.11 0.03 lasso 8 0.01 4.0e-02 -4.3 -7.9 3.8e-15 -0.44 0.03 0.89 TRUE
22 GTEx Muscle Skeletal RRP15 0.17 0.15 lasso 2 0.14 3.9e-14 9.4 9.6 1.4e-21 -0.05 1.00 0.00 FALSE
23 GTEx Ovary LYPLAL1 0.20 0.11 lasso 3 0.07 9.3e-03 5.6 -7.0 2.7e-12 0.04 0.10 0.09 FALSE
24 GTEx Pituitary RRP15 0.38 0.23 lasso 3 0.23 1.9e-06 9.3 10.1 6.7e-24 -0.03 0.34 0.06 FALSE
25 GTEx Skin Sun Exposed Lower leg RRP15 0.17 0.13 lasso 6 0.12 4.5e-10 9.0 8.9 8.0e-19 -0.07 1.00 0.00 FALSE
26 GTEx Testis RRP15 0.70 0.65 lasso 4 0.64 6.6e-36 9.4 9.3 1.4e-20 -0.06 1.00 0.00 FALSE
27 GTEx Testis ZC3H11B 0.33 0.28 lasso 3 0.27 1.5e-12 -11.4 -11.5 1.5e-30 0.04 0.00 1.00 TRUE
28 GTEx Thyroid RRP15 0.28 0.16 lasso 7 0.17 9.8e-13 9.0 10.0 1.6e-23 -0.03 1.00 0.00 FALSE
29 GTEx Thyroid TGFB2 0.14 0.07 lasso 2 0.06 2.8e-05 7.6 7.6 2.2e-14 0.24 0.82 0.01 TRUE
30 METSIM Adipose RRP15 0.28 0.24 bslmm 489 0.23 1.7e-34 9.0 10.5 7.7e-26 0.00 1.00 0.00 FALSE
31 YFS Blood LYPLAL1 0.02 0.01 bslmm 480 0.01 2.6e-05 -6.5 8.9 6.0e-19 -0.07 0.93 0.01 TRUE
32 The Cancer Genome Atlas Bladder Urothelial Carcinoma LYPLAL1 0.04 0.00 blup 39 0.01 1.9e-02 4.9 7.7 1.3e-14 -0.07 0.02 0.72 FALSE
33 The Cancer Genome Atlas Breast Invasive Carcinoma RRP15 0.11 0.11 lasso 5 0.10 2.5e-20 9.4 9.3 1.1e-20 -0.05 0.86 0.14 FALSE
34 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma RRP15 0.13 0.13 lasso 1 0.10 1.4e-05 9.3 9.3 9.8e-21 -0.06 0.69 0.11 FALSE
35 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma LYPLAL1 0.06 0.03 enet 6 0.03 9.5e-05 5.4 5.3 9.2e-08 -0.03 0.68 0.21 FALSE
36 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RRP15 0.07 0.07 lasso 2 0.06 2.0e-07 10.2 10.7 8.2e-27 -0.03 0.00 1.00 TRUE
37 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RRP15 0.17 0.11 enet 9 0.12 7.4e-13 9.4 7.9 3.2e-15 -0.03 0.86 0.14 FALSE
38 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma RRP15 0.14 0.04 enet 11 0.06 4.0e-04 9.4 8.2 2.2e-16 -0.03 0.11 0.39 FALSE
39 The Cancer Genome Atlas Brain Lower Grade Glioma LYPLAL1 0.09 0.08 blup 39 0.08 1.8e-09 5.0 6.1 1.1e-09 -0.04 0.98 0.02 FALSE
40 The Cancer Genome Atlas Brain Lower Grade Glioma RRP15 0.10 0.10 lasso 1 0.10 4.7e-11 9.4 9.4 5.0e-21 -0.05 0.86 0.14 FALSE
41 The Cancer Genome Atlas Lung Adenocarcinoma RRP15 0.09 0.09 lasso 3 0.09 3.2e-10 9.4 9.1 6.4e-20 -0.06 0.85 0.15 FALSE
42 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RRP15 0.10 0.09 lasso 3 0.08 9.8e-10 9.3 9.3 1.3e-20 -0.06 0.92 0.08 FALSE
43 The Cancer Genome Atlas Pancreatic Adenocarcinoma RRP15 0.16 0.04 blup 61 0.05 3.8e-03 9.3 7.4 1.6e-13 -0.03 0.01 0.15 FALSE
44 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma RRP15 0.15 0.12 lasso 2 0.12 1.9e-05 9.0 9.2 2.6e-20 -0.06 0.16 0.15 FALSE
45 The Cancer Genome Atlas Prostate Adenocarcinoma RRP15 0.29 0.29 lasso 2 0.29 2.7e-30 9.4 9.4 4.0e-21 -0.06 0.85 0.15 FALSE
46 The Cancer Genome Atlas Soft Tissue Sarcoma TGFB2 0.05 0.03 blup 73 0.03 4.5e-03 18.9 -16.9 5.2e-64 -0.90 0.01 0.88 TRUE
47 The Cancer Genome Atlas Stomach Adenocarcinoma RRP15 0.11 0.09 lasso 3 0.07 8.2e-06 9.3 9.3 1.5e-20 -0.06 0.24 0.72 FALSE
48 The Cancer Genome Atlas Thyroid Carcinoma RRP15 0.22 0.25 lasso 3 0.24 1.7e-23 9.4 9.4 3.6e-21 -0.06 0.85 0.15 FALSE
49 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma TGFB2 0.24 0.11 enet 10 0.14 1.4e-04 16.5 -16.8 2.4e-63 -0.80 0.08 0.63 FALSE