Best TWAS P=3.37e-37 · Best GWAS P=2.1e-35 conditioned to 0.00229
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | CTDP1 | 0.29 | 0.00 | enet | 31 | 0.03 | 6.9e-02 | 2.5 | -6.0 | 1.6e-09 | 0.29 | 0.07 | 0.1 | FALSE |
2 | METSIM | Adipose | NFATC1 | 0.12 | 0.07 | lasso | 5 | 0.07 | 3.5e-11 | -12.2 | -12.7 | 3.4e-37 | 0.85 | 0.00 | 1.0 | TRUE |
3 | YFS | Blood | NFATC1 | 0.17 | 0.08 | bslmm | 444 | 0.15 | 3.1e-46 | -9.5 | -9.3 | 9.0e-21 | 0.45 | 1.00 | 0.0 | FALSE |