Hub : Genes

CTDP1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.2920	0.0940	1.2e-03	-0.003	NA	0.027	NA	0.011	3.8e-01	NA	6.9e-02	NA	1.7e-01
2	GTEx	Colon Transverse	0.1760	0.0650	2.8e-03	0.099	NA	0.080	NA	0.087	1.9e-05	NA	1.2e-04	NA	6.0e-05
3	GTEx	Liver	0.2350	0.0820	3.9e-03	0.105	NA	0.061	NA	0.071	7.5e-04	NA	9.0e-03	NA	5.0e-03
4	GTEx	Muscle Skeletal	0.0654	0.0285	6.6e-03	0.002	NA	0.006	NA	0.021	1.9e-01	NA	7.0e-02	NA	3.2e-03
5	GTEx	Skin Not Sun Exposed Suprapubic	0.3290	0.0840	1.9e-04	0.050	NA	0.078	NA	0.047	1.0e-03	NA	4.7e-05	NA	1.3e-03
6	GTEx	Skin Sun Exposed Lower leg	0.1690	0.0460	3.0e-05	0.097	NA	0.083	NA	0.099	2.2e-08	NA	2.3e-07	NA	1.5e-08
7	GTEx	Whole Blood	0.2570	0.0430	1.1e-16	0.315	NA	0.309	NA	0.318	1.4e-29	NA	6.3e-29	NA	7.0e-30
8	YFS	Blood	0.0252	0.0095	2.0e-04	0.010	0.011	0.015	0.014	0.018	1.6e-04	1e-04	6.6e-06	2e-05	9.7e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.7	1.1	4.3	-0.0	-2.1	-0.2	0.2	-1.6	-1.4	0.3	-0.0
Bipolar Disorder or Schizophrenia	2.1	5.1	11.9	1.6	-1.3	1.5	3.1	-2.8	-3.5	-2.0	-1.1
Depressed Affect (Nagel 2018)	3.0	6.3	13.6	3.1	0.6	3.7	2.4	-1.7	-2.1	-3.0	-2.3
Depression (Nagel 2018)	0.9	1.3	2.8	1.1	0.7	1.2	1.7	-1.0	-0.9	-1.6	-0.2
Intelligence (Savage-Jansen 2018)	0.9	2.8	6.6	-1.1	0.3	-1.0	-2.0	2.3	2.6	1.3	1.6
Neuroticism (Nagel 2018)	4.3	10.2	19.2	4.4	2.5	4.3	2.9	-0.7	-1.6	-4.3	-2.8
Schizophrenia (2018)	3.0	6.2	14.8	1.9	0.0	2.2	3.9	-2.4	-3.3	-2.8	-1.4
Schizophrenia vs Biploar Disorder	1.2	1.6	6.6	2.6	1.1	1.6	0.6	0.5	0.4	-1.2	0.2
Worry (Nagel 2018)	2.3	4.9	15.6	3.9	2.3	2.4	1.7	-0.1	-0.3	-2.9	-1.0
Alzheimer’s Disease (in mother)	0.2	0.3	0.6	-0.6	-0.4	-0.4	0.0	-0.2	-0.8	0.3	-0.8
Alzheimer’s Disease (in father)	0.3	0.3	1.2	-0.3	0.7	-0.4	0.3	1.1	0.4	0.0	0.3
Alzheimer’s Disease (including proxy)	0.2	0.2	0.6	-0.7	-0.1	-0.7	-0.4	0.1	-0.0	0.7	-0.1
Crohns Disease (2017)	1.0	2.2	7.4	0.6	-0.1	-1.5	-2.7	1.4	1.6	1.6	-0.2
Irritable Bowel Disease (IBD)	0.6	1.5	8.0	0.1	-0.5	-1.2	-2.8	0.4	0.7	1.3	-0.1
Ulcerative Colitis (UC)	0.4	0.8	5.4	-0.6	-0.5	-0.4	-2.3	-0.5	-0.1	0.5	-0.3
Major Depression (MDD)	0.4	0.5	1.4	0.0	1.2	0.6	0.5	0.0	0.2	-1.2	-0.5
Reaction Time	3.4	6.5	11.0	2.9	1.2	3.3	3.2	-1.5	-2.1	-3.3	-2.0
Verbal and Numeric Reasoning (VNR)	1.3	3.1	5.7	0.3	0.4	-1.5	-2.4	2.3	2.3	1.4	2.0
Breast Cancer	0.5	1.3	4.0	-0.0	0.8	-1.4	-0.9	2.0	1.5	0.7	0.7
Ovarian Cancer	0.7	0.9	2.6	0.1	-0.9	-1.6	-1.1	0.2	1.2	1.2	0.2
Prostate Cancer	0.4	0.5	1.7	-0.8	-0.4	-0.7	1.3	-1.0	0.1	0.3	0.2
Age at First Birth	0.6	0.9	2.3	-0.5	1.5	0.7	-0.8	1.0	1.5	-0.2	-0.7
Bipolar Disorder (2011)	1.3	1.3	3.3	0.9	-1.5	0.0	1.1	-1.4	-1.8	-0.3	-0.8
Body Mass Index (BMI) (2010)	0.4	0.6	2.0	0.8	0.0	-0.3	0.2	-1.4	-0.5	-0.2	-1.3
Coronary Artery Disease (CAD)	0.9	1.1	2.2	0.6	1.0	1.3	1.4	-0.4	-0.6	-1.1	-1.5
Crohns Disease (2012)	0.6	1.0	2.5	1.6	-1.0	-1.5	-1.0	0.0	-0.0	1.1	-0.6
Mean Putamen Volume	1.0	1.1	6.1	-2.5	0.6	-0.3	-0.6	-0.1	0.7	0.5	1.1
Fasting Glucose	0.2	0.3	0.9	-0.9	-0.1	0.1	0.4	-0.1	-0.5	0.1	0.9
HbA1C	2.4	2.7	10.5	-3.2	0.8	-0.5	-0.9	1.9	1.5	1.3	1.4
HDL Cholesterol	0.4	0.7	1.6	-1.3	-0.6	-1.0	-1.2	0.5	0.1	0.6	0.4
LDL Cholesterol	0.5	0.7	2.6	0.7	-0.1	-0.3	-1.5	1.6	0.2	0.2	0.4
Lupus	1.2	1.9	3.7	-1.1	-0.5	-1.6	-1.8	1.9	0.7	1.7	0.8
Neuroticism (2016)	1.7	2.5	8.6	2.9	0.4	2.5	0.5	-0.7	-0.4	-2.0	0.3
Primary Biliary Cirrhosis	0.5	0.7	1.3	0.8	1.1	1.1	0.4	1.1	0.6	-0.8	-0.2
Rheumatoid Arthritis	2.7	3.8	6.1	2.2	2.2	2.5	0.3	2.5	1.4	-2.0	-1.5
Schizophrenia (2014)	1.5	3.4	8.0	2.1	-0.8	1.4	2.8	-1.6	-2.7	-1.4	-0.5
Triglycerides	0.3	0.6	1.3	0.7	-0.1	-0.6	-1.0	0.8	0.7	1.1	0.5
Type 2 Diabetes (T2D) (2012)	1.2	1.3	3.7	0.1	-0.2	-1.6	-0.1	0.5	1.7	1.9	1.3
Ulcerative Colitis	0.4	0.5	1.9	0.6	-0.8	-0.2	-0.8	-1.4	-0.7	-0.0	-0.5
Blood Eosinophil Count	0.1	0.4	2.0	1.4	0.3	-0.4	-0.7	0.4	0.5	0.5	0.6
Blood Platelet Count	1.0	11.6	26.4	-2.5	-0.6	-3.9	-5.1	2.5	2.9	4.1	3.7
Blood Red Count	0.4	3.9	9.1	-0.8	-2.9	-3.0	-2.1	0.9	-1.2	2.6	-0.1
Blood White Count	1.0	7.6	14.6	3.8	2.2	2.3	2.6	-0.8	-1.9	-3.8	-3.2
Heel T-Score	0.2	1.4	7.2	2.7	-1.2	-0.9	-0.6	-0.0	0.2	0.6	0.9
BMI	0.2	1.2	6.2	2.5	-0.8	-0.3	0.5	-0.3	-1.1	0.3	-1.1
Height	0.3	5.5	36.5	-6.0	-0.7	-1.9	-0.5	-0.3	0.6	1.6	0.6
Waist Hip Ratio (WHR)	0.1	0.7	2.8	-1.2	0.2	-0.3	-0.6	1.7	-0.1	0.3	0.7
Systolic Blood Pressure	0.2	0.8	3.6	0.5	-0.5	-1.9	0.0	0.1	0.5	1.2	0.6
Smoking Status	3.2	7.6	21.7	2.3	-1.7	0.4	2.3	-4.3	-4.7	-1.2	-2.4
Allergy or Eczema	2.0	5.4	12.0	-1.0	-2.2	-3.1	-2.1	0.4	1.0	3.5	3.2
Cardiovascular Disease	0.8	2.7	6.8	2.1	-1.5	-2.6	-0.9	-0.3	-0.9	2.4	1.0
Hypothyroidism (self reported)	0.7	1.5	4.7	2.2	-0.3	1.1	1.5	0.1	-1.2	-1.2	-1.0
Respiratory disease	0.6	1.4	5.8	0.7	-1.6	-0.1	0.7	-1.3	-2.4	0.3	0.5
Type 2 Diabetes (T2D) (2018)	0.9	1.6	5.2	0.4	-2.3	-1.7	-0.6	-0.2	-0.9	1.8	0.2
Lung FEV1/FVC ratio	0.3	1.5	6.1	2.5	0.5	0.7	1.3	-0.9	-0.4	-1.2	-1.0
Lung FVC	0.7	3.5	6.9	0.8	2.2	2.5	2.1	-1.1	0.2	-2.6	-1.7
Neuroticism	3.9	9.3	18.4	4.3	2.5	4.3	2.6	-0.6	-1.3	-4.3	-2.1
Chronotype (morning person)	1.1	2.6	7.0	-2.6	2.5	0.0	-0.3	1.5	2.2	-0.4	-0.3
Hair Pigment	0.0	0.7	1.8	1.0	-0.4	0.9	-0.8	-1.4	-0.4	-0.9	0.2
Tanning	0.5	6.4	13.3	-2.9	-1.0	-3.6	-3.0	1.0	2.1	3.2	2.2
Hand grip strength (left)	0.4	1.0	2.8	-0.7	-0.7	0.2	1.2	-1.6	-1.7	-0.4	0.0
Number of treatments/medications taken	1.9	3.4	8.8	2.5	-1.3	0.9	2.5	-1.6	-3.0	-0.5	-0.8
Average weekly spirits intake	0.6	0.8	3.5	0.6	-1.9	-0.6	0.4	-0.8	-0.6	1.0	-0.1
Sensitivity / hurt feelings	6.7	11.4	21.8	2.9	2.3	4.7	3.5	-1.5	-2.4	-4.6	-3.7
Frequency of depressed mood in last 2 weeks	0.8	1.2	2.5	0.7	0.8	1.4	1.5	-0.5	-1.2	-1.6	-0.3
Hearing difficulty/problems: Yes	0.7	1.1	1.9	1.4	0.2	1.2	1.4	-1.0	-0.7	-1.3	0.6
Relative age of first facial hair	1.2	2.5	6.7	2.4	-1.8	-0.1	0.4	-2.6	-2.0	-0.2	-0.2
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.8	0.5	0.6	0.6	-0.9	0.4	-0.2	-0.2	-0.5
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.5	-1.2	0.1	-0.7	1.2	-0.9	-0.5	-0.3	-0.3
Ever had hysterectomy (womb removed)	1.9	2.2	5.7	0.7	-0.5	0.2	2.1	-1.8	-2.4	-1.2	-1.5
Systolic blood pressure, automated reading	0.2	0.5	1.8	0.0	0.7	-1.3	0.4	0.6	1.0	0.4	0.3
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.8	-0.7	-1.6	-0.5	0.2	-1.2	-1.7	0.6	0.5
Angina	1.3	1.7	4.0	2.0	-0.5	1.3	1.4	-1.1	-1.4	-0.9	-1.3
Medication for hormone replacement therapy	4.3	4.8	10.2	0.3	0.1	2.5	2.6	-2.9	-3.2	-2.4	-0.8
Vitamin and mineral supplements	0.6	0.7	2.6	-1.6	-0.1	-0.5	-0.7	1.6	0.5	0.0	-0.1
Supplements: Zinc	0.3	0.3	0.9	-0.8	-0.2	0.3	1.0	-0.4	0.1	0.7	0.4
Medication: Co-codamol	0.8	1.0	1.9	0.5	0.7	0.2	1.4	-1.0	-1.4	-0.7	-1.3
Medication: Metformin	2.4	3.4	11.3	-1.0	-1.8	-3.4	-1.6	0.4	0.2	2.8	0.9
Diabetes (father)	3.6	4.5	13.6	-0.3	2.9	-0.9	-1.2	3.3	3.7	0.3	0.1
Diabetes (mother)	1.8	2.3	7.0	1.3	-2.6	-0.8	-0.9	-1.3	-2.3	1.0	-0.8
Severe depression (siblings)	1.6	1.8	3.3	0.8	1.2	1.5	1.8	-0.5	-1.5	-1.8	-1.2
Pack years adult smoking proportion	0.4	0.7	2.5	0.8	-0.5	-0.1	0.5	-0.7	-1.6	-0.2	-1.1
Impedance of leg (right)	0.3	1.7	4.2	2.0	0.8	1.2	1.4	-0.1	-0.8	-2.0	-0.7
Leg fat-free mass (left)	0.3	1.7	5.2	-2.3	-1.7	-1.4	-0.6	-0.4	-0.6	1.7	-0.1
Trunk fat percentage	0.3	1.1	5.0	2.2	-0.4	0.2	1.0	0.1	-0.7	-0.4	-1.5
Hand grip strength (right)	0.2	0.6	1.8	-0.2	-0.3	0.4	1.3	-1.1	-1.2	-0.5	-0.1
Townsend deprivation index at recruitment	1.1	1.5	4.5	1.1	-1.0	0.4	1.7	-0.9	-2.1	-0.7	-1.2
Current tobacco smoking	2.4	3.9	14.2	1.3	-1.6	0.1	2.0	-2.6	-3.8	-0.8	-1.1
Average weekly fortified wine intake	0.8	0.9	2.3	-0.6	1.5	-0.2	0.6	1.5	1.4	-0.4	-0.1
Maternal smoking around birth	0.8	1.2	3.8	1.1	-0.9	-0.4	0.7	-1.7	-2.0	-0.2	0.2
Fed-up feelings	2.2	3.9	7.2	2.7	0.1	2.6	1.6	-1.8	-1.7	-2.4	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	4.0	1.0	-0.3	0.6	2.0	-1.4	-1.6	-1.2	0.5
Relative age voice broke	1.4	2.2	5.1	1.0	-2.3	-1.7	-1.2	-1.6	-0.8	1.7	1.0
Taking other prescription medications	2.0	3.1	6.5	2.0	-0.9	1.0	2.2	-2.5	-2.5	-0.8	-1.0
Age when periods started (menarche)	0.3	0.7	2.3	1.5	0.5	1.0	-0.2	-0.6	0.3	-1.1	0.3
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	2.8	0.7	-1.4	-0.2	0.7	-1.3	-1.7	0.0	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.5	9.5	1.0	-0.5	-2.0	-3.1	1.5	2.1	2.1	1.5
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	3.5	-0.8	-0.8	-1.4	-1.9	0.7	0.3	1.4	0.3
Qualifications: CSEs or equivalent	2.0	2.7	7.4	1.0	-2.7	-0.7	1.2	-2.6	-2.1	0.5	0.1
Serious illness, injury or assault to yourself	0.8	0.9	2.8	0.1	0.7	0.9	0.7	0.4	-1.4	-0.9	-1.7
High blood pressure	0.7	1.9	4.7	2.2	-1.6	-1.2	0.2	-1.4	-1.8	1.0	-0.2
Hayfever, allergic rhinitis or eczema	2.8	6.1	15.0	-1.8	-2.1	-2.9	-2.3	0.9	1.3	3.9	3.0
Multivitamins +/- minerals	0.1	0.2	0.5	0.5	-0.2	0.2	-0.1	-0.7	-0.1	0.3	0.5
Stomach or abdominal pain in last month	1.3	1.7	3.4	1.4	0.9	0.9	1.2	-0.6	-1.1	-1.8	-1.7
Supplements: Glucosamine	0.5	0.7	1.9	-0.2	-0.1	1.4	1.3	-1.1	-0.5	-0.7	-0.3
Diverticular disease/diverticulitis (self-reported)	2.1	2.5	6.9	1.0	-0.5	0.5	1.7	-1.5	-2.6	-1.1	-2.3
Medication: Atenolol	0.2	0.2	1.0	-0.2	0.1	0.5	1.0	0.1	-0.3	-0.4	-0.5
Medication: Levothyroxine sodium	1.8	3.0	11.7	3.4	0.0	1.5	1.9	-0.3	-1.2	-1.3	-1.8
Sitting height	0.1	0.8	1.7	-1.0	-1.3	-1.3	-0.5	-0.6	-0.5	1.0	-0.3
Chronic bronchitis/emphysema (father)	1.0	1.2	3.9	-0.1	-0.1	0.7	0.7	-2.0	-2.0	-0.6	-0.6
High blood pressure (mother)	0.4	0.6	1.1	-0.5	-0.9	-0.7	-0.4	1.0	0.4	1.1	0.9
Body mass index (BMI)	0.2	0.7	2.5	1.6	-0.7	-0.7	0.5	-0.1	-0.7	0.5	-1.2
Impedance of leg (left)	0.5	2.4	5.0	2.1	0.5	1.5	1.9	-0.9	-1.4	-2.2	-0.8
Leg predicted mass (left)	0.3	1.6	4.7	-2.2	-1.8	-1.4	-0.5	-0.4	-0.6	1.6	-0.1
Trunk fat mass	0.2	0.7	1.6	1.1	-0.9	-0.5	0.7	-0.2	-0.9	0.3	-1.2
Waist circumference	0.1	0.5	1.7	0.2	-0.7	-0.4	0.6	-0.4	-0.9	0.2	-1.3
Number of incorrect matches in round	1.5	2.6	6.3	-1.6	-0.6	-2.0	-1.7	0.5	1.1	2.5	1.7
Past tobacco smoking	1.2	2.1	6.3	-1.5	1.3	-0.1	-0.5	2.5	2.3	0.4	1.1
Alcohol usually taken with meals	0.2	0.3	0.9	-0.6	0.1	0.5	0.9	0.2	0.5	-0.3	0.8
Nervous feelings	0.7	1.2	3.6	1.3	0.9	0.3	1.9	0.3	0.3	-1.1	1.4
Frequency of tenseness / restlessness in last 2 weeks	2.3	3.5	8.1	1.3	0.2	2.4	2.5	-1.2	-2.8	-2.1	-1.0
Hearing difficulty/problems with background noise	0.4	0.6	1.8	-0.4	-1.4	-0.4	0.3	-0.2	-0.3	0.9	1.2
Hair/balding pattern: Pattern 2	1.5	2.0	5.3	0.9	1.2	1.6	2.3	-0.3	-1.0	-2.0	-0.8
Had menopause	0.8	1.0	4.5	-1.2	-0.3	0.0	2.1	-1.0	-0.9	-0.5	0.2
Had other major operations	1.2	1.5	5.2	0.9	-0.8	0.2	-0.2	-2.1	-2.3	-0.0	-0.9
Forced vital capacity (FVC)	0.1	0.5	1.9	-1.4	-0.6	0.4	1.0	-0.6	0.1	-0.2	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	3.1	1.5	-0.4	-1.0	-1.8	0.8	1.3	0.9	0.4
Ever unenthusiastic/disinterested for a whole week	3.0	3.7	6.1	2.5	0.6	2.4	2.0	-1.9	-1.8	-2.0	-1.5
Qualifications: None of the above	0.4	0.9	3.2	0.9	-0.9	-0.1	0.2	-1.6	-1.8	-0.3	-0.2
Financial difficulties in last 2 years	1.7	2.3	5.6	-0.6	-2.4	-1.5	-1.8	-0.6	-1.1	1.9	1.5
Mouth/teeth dental problems	1.7	2.7	5.5	-1.6	1.4	-1.5	-1.2	2.3	2.3	1.1	1.1
Heart attack	0.4	0.5	1.3	1.0	-1.2	-0.7	0.1	-0.3	-0.5	0.7	0.7
Allergy	1.1	2.5	6.1	1.0	2.1	1.8	1.0	0.7	0.9	-2.5	-1.8
Pain all over the body in last month	0.5	0.5	2.0	1.4	0.4	-0.2	1.0	0.6	-0.5	-0.1	-0.1
Diabetes (self-reported)	0.9	1.4	3.9	-0.1	-2.0	-1.0	-0.4	-1.2	-1.7	1.1	0.2
Hayfever/allergic rhinitis (self-reported)	5.7	7.5	14.3	-2.1	-2.6	-2.5	-3.8	0.9	0.9	3.7	3.6
Medication: Ramipril	0.6	0.7	3.2	1.8	0.7	-0.1	-0.6	-0.1	-0.3	-0.1	-1.3
Medication: Simvastatin	1.1	1.6	4.6	-0.2	-0.6	-2.2	-1.1	1.1	1.0	1.7	1.0
Fluid intelligence score	1.1	2.3	6.8	0.5	0.2	-1.2	-1.3	2.6	2.3	0.9	1.4
Illnesses of siblings	0.5	0.7	3.4	-1.8	-0.3	0.5	-1.2	0.0	-0.2	0.4	0.5
Neuroticism score	1.4	2.9	6.8	2.6	1.0	2.4	1.9	-0.6	-1.0	-2.1	-0.8
Weight	0.2	0.8	1.4	-0.4	-1.2	-0.8	0.8	-0.6	-1.1	0.6	-1.2
Impedance of arm (right)	0.3	1.5	4.4	1.3	0.9	1.9	1.0	-0.1	-0.1	-2.1	-0.2
Arm fat percentage (right)	0.2	1.0	4.9	2.2	-0.6	-0.6	0.2	0.1	-0.7	0.1	-1.2
Trunk fat-free mass	0.4	2.1	11.5	-3.4	-1.1	-1.3	0.0	-0.5	-0.9	1.1	-0.5
Hip circumference	0.1	0.4	1.6	0.7	-0.3	-0.3	1.0	0.0	0.1	-0.0	-1.3
Time employed in main current job	1.0	1.1	2.0	1.4	1.2	1.1	1.4	0.3	1.1	-1.0	-0.6
Alcohol intake versus 10 years previously	2.7	4.0	8.3	2.9	-0.6	2.0	1.0	-2.4	-2.4	-2.0	-1.6
Father’s age at death	0.3	0.4	1.4	-1.2	-0.7	0.2	-0.4	-0.3	0.3	0.5	0.6
Worrier / anxious feelings	1.5	2.9	6.5	2.5	1.0	2.4	1.4	-0.1	-1.1	-2.2	-1.3
Frequency of tiredness / lethargy in last 2 weeks	3.4	5.4	8.9	3.0	0.1	2.5	2.8	-1.3	-2.8	-2.6	-2.0
Falls in the last year	1.0	1.4	2.7	-0.6	-1.7	-1.2	-0.3	-1.3	-1.6	1.1	0.9
Hair/balding pattern: Pattern 3	0.8	1.1	4.9	-2.2	-0.5	-1.1	0.0	-0.9	-0.3	1.1	-0.7
Number of live births	0.5	0.7	2.6	-0.2	0.6	-0.8	-1.6	1.1	0.3	0.6	0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	1.6	-0.5	-0.6	0.8	1.3	-0.9	-0.5	-0.6	-0.2
Pulse rate	0.8	1.3	3.6	0.1	-0.4	-1.2	-1.4	1.9	0.7	1.2	0.9
Happiness	1.3	1.6	3.2	0.3	-0.1	1.8	1.6	-0.8	-1.4	-1.7	-1.2
Noisy workplace	1.2	1.5	3.7	1.9	0.6	1.1	-0.1	-0.9	-1.4	-1.8	-0.6
Qualifications: A levels/AS levels or equivalent	0.8	1.8	4.9	-2.2	-0.5	-0.5	-1.3	1.6	1.5	1.3	1.0
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	4.3	-0.4	-1.8	-1.5	-0.7	0.6	-0.4	2.1	1.6
Mouth/teeth dental problems: Dentures	0.7	1.2	3.1	-1.3	-1.4	-0.7	-0.3	-1.8	-1.4	0.3	-0.7
Asthma	0.8	1.7	7.2	0.3	-1.3	-0.2	0.7	-1.7	-2.7	0.4	0.8
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	6.3	0.4	-2.5	0.2	-0.1	-1.7	-1.5	0.8	0.3
Medication: Cholesterol lowering	1.1	1.7	3.4	0.0	0.3	-1.7	-1.8	1.6	1.5	1.6	-0.3
Depression (self-reported)	0.4	0.5	1.1	0.9	0.5	0.6	0.1	-1.0	-1.1	-0.6	-0.4
Medication: Lansoprazole	1.3	1.5	4.9	-0.6	-1.6	-1.3	-0.1	-1.2	-2.2	0.9	0.7
Prospective memory result	0.8	1.0	2.8	0.5	-0.4	1.7	0.9	-0.7	-1.1	-1.1	-0.9
Lung cancer (father)	2.9	3.3	5.9	0.9	1.2	1.9	2.2	-2.4	-0.7	-2.2	-2.2
Illnesses of mother	1.1	1.3	3.3	0.2	1.8	0.8	-0.7	0.9	1.3	-1.1	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	0.8	-0.4	0.2	0.9	0.9	-0.3	0.3	-0.7	-0.4
Pulse wave Arterial Stiffness index	0.4	0.4	0.9	0.5	0.9	-0.8	0.4	0.7	0.9	0.1	0.3
Impedance of arm (left)	0.3	1.3	3.2	1.3	1.2	1.8	0.6	0.6	0.6	-1.7	-0.2
Arm fat mass (right)	0.2	0.8	1.6	1.3	-1.1	-1.0	0.4	-0.4	-1.0	0.5	-1.2
Trunk predicted mass	0.3	2.0	10.7	-3.3	-1.1	-1.2	0.0	-0.5	-0.9	1.1	-0.5
Standing height	0.3	2.7	17.1	-4.1	-1.2	-0.4	0.6	-1.1	-1.0	0.4	-0.2
Length of working week for main job	0.8	0.9	4.7	2.2	-1.0	0.5	0.1	-0.2	-0.3	-0.5	0.9
Exposure to tobacco smoke at home	0.2	0.2	0.6	0.7	-0.8	0.1	0.2	-0.7	-0.5	-0.2	0.1
Breastfed as a baby	0.6	0.8	3.8	-0.8	-0.6	-0.2	-1.9	-0.8	-1.0	-0.1	0.1
Tense / ‘highly strung’	1.7	2.9	6.2	2.5	0.8	1.5	1.9	-1.1	-1.7	-2.3	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.2	7.0	1.8	-0.8	0.7	0.9	-2.2	-2.6	-0.9	-0.5
Hair/balding pattern: Pattern 4	0.3	0.6	2.1	-0.5	-0.7	-0.6	-1.5	0.1	0.7	0.9	0.6
Birth weight of first child	1.0	1.8	3.8	-1.2	-1.7	-1.7	-0.6	-1.0	-0.2	1.4	2.0
Peak expiratory flow (PEF)	0.3	0.7	2.0	0.2	-0.1	1.1	0.8	-0.5	-1.4	-0.8	-0.8
Pulse wave reflection index	0.4	0.5	2.2	1.5	0.7	0.0	0.7	-0.2	0.2	-0.3	0.6
Ever highly irritable/argumentative for 2 days	2.1	2.5	6.8	2.6	-1.1	1.3	1.6	-1.6	-2.0	-1.1	-0.5
Loud music exposure frequency	1.4	1.5	3.3	1.8	-1.0	1.6	0.7	-1.4	-1.3	-0.8	0.2
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	3.5	-1.9	1.0	-0.0	-1.3	1.7	1.4	0.3	-0.7
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	4.5	2.1	-0.3	1.0	-0.1	-1.1	-1.2	-0.4	-0.4
Blood clot in the leg (DVT)	0.6	0.8	2.7	-1.7	0.2	-0.6	-0.8	1.0	0.1	0.5	1.0
Medication: Paracetamol	0.6	1.0	2.7	1.0	-1.0	-0.1	1.3	-1.2	-1.7	-0.3	0.5
Headache pain in last month	1.9	3.3	8.3	1.7	-1.0	0.6	2.9	-2.6	-2.3	-0.9	-0.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.1	-0.6	-0.1	1.5	0.8	-1.1	-0.7	-1.4	-0.0
Glaucoma (self-reported)	0.8	0.9	3.9	0.1	-1.0	-0.9	-2.0	0.1	0.3	1.2	0.5
Gout (self-reported)	0.9	1.3	3.5	1.9	1.1	1.4	0.8	0.1	0.3	-1.4	-1.0
Hypothyroidism/myxoedema (self-reported)	1.3	2.6	7.6	2.8	0.0	1.5	2.0	-0.4	-1.4	-1.5	-1.6
Medication: Amlodipine	2.1	3.0	7.4	-1.5	-2.7	-2.3	-0.4	-1.4	-1.5	2.1	0.2
Medication: Ventolin 100micrograms inhaler	1.6	2.1	7.4	1.7	-1.0	1.1	0.5	-1.6	-2.7	-1.1	-0.5
Birth weight	0.6	1.2	4.2	-2.0	0.9	-0.4	0.6	1.5	0.7	0.1	1.2
Chronic bronchitis/emphysema (mother)	1.7	2.0	5.3	0.9	-1.5	-0.1	1.4	-2.3	-2.3	-0.2	-0.4
High blood pressure (siblings)	0.5	0.7	3.8	1.9	-0.5	-0.3	0.8	-0.8	0.2	-0.2	-0.5
Forced vital capacity (FVC), Best measure	0.1	0.4	1.0	-0.9	0.4	1.0	0.6	-0.2	0.6	-0.8	-0.2
Body fat percentage	0.3	1.3	5.9	2.4	-0.7	-0.3	0.6	-0.2	-1.1	-0.0	-1.6
Leg fat percentage (right)	0.5	1.7	6.8	2.6	-1.1	-1.0	0.5	-0.5	-1.4	0.3	-1.5
Arm fat-free mass (right)	0.3	1.5	4.5	-2.1	-1.3	-1.4	0.3	-0.4	-1.0	1.2	-0.8
Exposure to tobacco smoke outside home	0.8	1.1	4.3	0.4	-1.2	-0.1	1.4	-0.8	-2.1	0.2	0.4
Comparative body size at age 10	0.5	1.5	4.0	-0.7	-0.8	-1.4	-1.2	1.6	0.9	2.0	-0.1
Number of full brothers	0.7	0.9	2.9	1.7	0.3	1.4	-0.7	-0.7	0.2	-1.1	-0.5
Worry too long after embarrassment	0.8	1.3	3.5	1.9	0.8	1.7	1.0	-0.1	-0.2	-1.4	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	6.0	0.9	-0.9	0.4	1.7	-1.7	-2.5	-0.5	-0.1
Wheeze or whistling in the chest in last year	2.0	3.5	14.4	1.0	-1.9	-0.6	2.0	-2.1	-3.8	-0.3	-0.6
Number of children fathered	2.5	2.8	5.1	-1.9	-1.4	-1.0	-2.3	1.5	1.0	1.8	2.0
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	4.7	-2.2	0.6	-0.2	1.0	-0.2	0.2	0.3	-0.1
Age at first live birth	3.5	6.2	12.5	-3.5	-0.3	-2.4	-3.5	2.5	2.1	2.5	1.4
Pulse wave peak to peak time	0.4	0.4	0.9	-0.5	-0.9	0.8	-0.5	-0.7	-0.8	-0.1	-0.5
Health satisfaction	1.5	2.0	5.0	1.4	-0.7	0.4	1.7	-0.9	-1.9	-0.8	-2.2
Shortness of breath walking on level ground	0.7	0.9	3.4	-0.4	-0.7	-1.3	-1.8	0.3	-0.5	0.9	-0.2
Qualifications: College or University degree	1.2	3.8	8.8	-3.0	-0.8	-1.2	-2.0	1.9	2.4	2.0	1.5
Eye problems/disorders: None of the above	0.3	0.3	1.4	0.2	0.6	0.3	0.3	0.7	1.2	-0.1	-0.4
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.4	0.3	-0.5	-0.5	0.6	-0.3	-0.1	0.4	-0.1
Emphysema/chronic bronchitis	1.2	1.3	3.9	1.0	-0.5	0.6	2.0	-0.3	-1.9	-1.0	-0.7
Medication for pain relief, constipation, heartburn	1.5	2.6	5.9	-2.1	1.3	-0.5	-1.8	2.3	2.4	0.4	0.2
Neck or shoulder pain in last month	0.6	0.9	2.6	1.6	-1.3	-0.3	-0.6	-0.4	-1.4	0.3	0.3
Medication: Blood pressure	0.8	1.3	3.5	0.9	-0.8	-1.9	-0.6	0.8	0.3	1.8	1.2
Angina (self-reported)	1.1	1.4	4.2	2.0	-0.5	1.1	1.1	-1.0	-1.3	-0.7	-1.1
Migraine (self-reported)	0.4	0.5	1.2	0.9	0.5	0.3	0.7	-1.1	-0.5	-0.7	-0.2
Medication: Ibuprofen	1.6	1.9	6.4	1.1	-2.5	0.9	0.2	-1.7	-1.9	0.4	-0.4
Medication: Allopurinol	0.4	0.5	1.5	1.0	0.4	0.2	-0.4	0.8	1.2	-0.0	0.4
Medication: Omeprazole	0.5	0.6	2.0	-0.1	-1.3	-0.2	0.3	-0.9	-1.4	0.4	-0.6
Medication: Seretide 50 evohaler	0.2	0.2	0.7	-0.1	-0.4	-0.6	0.4	-0.3	-0.9	0.1	0.1
Mean time to correctly identify matches	5.8	11.1	19.2	3.4	1.4	4.4	4.0	-2.6	-2.9	-4.4	-2.6
Heart disease (mother)	0.6	0.7	2.4	0.2	-1.6	-0.7	0.2	-0.8	-0.5	0.7	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	3.1	1.1	-1.5	-0.5	0.3	-1.1	-1.8	0.2	0.3
Whole body fat mass	0.2	0.9	1.8	1.3	-1.1	-0.7	0.3	-0.4	-1.2	0.4	-1.3
Leg fat mass (right)	0.4	1.5	2.8	1.5	-1.4	-1.0	0.5	-0.8	-1.7	0.4	-1.7
Arm predicted mass (right)	0.3	1.4	4.3	-2.1	-1.3	-1.3	0.2	-0.5	-1.1	1.1	-0.8
Pulse rate, automated reading	0.5	1.6	8.4	2.9	-1.4	-0.6	-0.6	0.4	-1.1	0.4	0.3
Alcohol intake frequency.	1.6	3.8	7.8	2.7	-0.0	1.8	1.5	-2.8	-2.2	-1.7	-1.4
Comparative height size at age 10	0.7	3.6	8.9	-1.6	-0.4	2.5	3.0	-1.1	-1.9	-1.6	-1.9
Number of full sisters	1.3	1.6	4.8	1.3	0.8	0.1	1.4	0.3	-1.7	-1.0	-2.2
Suffer from ‘nerves’	0.8	1.2	4.2	2.1	1.4	-0.1	0.4	0.6	0.8	-0.7	1.4
Overall health rating	1.3	2.9	9.8	2.2	-1.5	0.3	1.2	-1.6	-3.1	-0.5	-1.2
Chest pain or discomfort	1.0	1.5	3.4	1.7	-0.5	0.4	1.8	-1.2	-1.7	-0.8	-0.5
Had major operations	0.4	0.5	2.1	-0.6	-0.5	-0.0	0.4	-1.4	-0.7	-0.1	0.6
Age at last live birth	3.1	4.4	8.4	-2.7	1.1	-1.4	-2.9	2.6	2.2	1.4	1.7
Family relationship satisfaction	1.0	1.3	4.7	0.0	-0.7	0.6	2.2	-0.9	-1.8	-0.5	-0.5
Leg pain on walking	0.3	0.4	1.1	1.0	-0.8	0.0	0.2	-0.2	-1.1	-0.1	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	0.8	0.9	0.6	0.2	0.7	0.6	0.6	-0.5	-0.9
Commuting to job workplace: Car/motor vehicle	0.8	0.9	3.4	-0.6	-1.1	-0.2	-1.1	-0.7	-1.8	0.5	-0.1
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	2.1	0.4	0.7	-0.0	1.4	-1.3	0.7	-1.0	0.1
Medication: Aspirin	2.5	3.3	9.4	2.5	-0.4	0.3	3.1	-1.7	-2.1	-1.1	-1.5
Supplements: Vitamin C	1.8	2.1	4.9	2.2	-0.6	1.1	1.4	-2.2	-1.6	-0.4	-1.0
Knee pain experienced in last month	0.5	0.8	2.3	0.2	-0.9	0.2	1.3	-1.2	-1.5	-0.3	-0.0
Hypertension (Self-reported)	0.7	1.9	4.4	2.1	-1.8	-1.5	0.2	-1.2	-1.6	1.2	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.3	2.7	9.9	-0.0	-1.6	0.2	1.6	-2.5	-3.1	-0.2	-0.7
Illnesses of father: Heart disease	0.7	1.0	2.7	-0.2	0.1	-1.1	-1.6	1.6	0.5	0.9	0.3
Illnesses of siblings: Diabetes	0.5	0.6	2.1	1.4	0.3	0.7	-0.4	0.1	0.3	-0.7	-1.0
Smoking status: Previous	0.7	1.1	3.1	1.1	0.2	0.5	0.2	-1.5	-1.1	-0.8	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.3	-1.1	-0.8	-1.0	-0.2	0.3	0.5	1.0	0.4
Whole body fat-free mass	0.4	2.0	8.6	-2.9	-1.5	-1.3	-0.1	-0.6	-1.0	1.3	-0.4
Leg fat-free mass (right)	0.3	1.8	6.0	-2.4	-1.9	-1.1	-0.3	-0.7	-0.8	1.5	-0.0
Arm fat percentage (left)	0.2	0.9	4.7	2.2	-0.5	-0.7	0.1	0.4	-0.5	0.3	-1.2
Average weekly red wine intake	0.7	1.0	2.2	-1.5	0.3	-1.1	-1.1	0.8	1.0	0.9	1.0
Handedness (chirality/laterality): Left-handed	0.8	0.9	3.2	0.6	1.4	1.0	0.6	-0.6	0.3	-1.8	-0.5
Mood swings	1.2	2.2	4.9	2.2	-0.6	1.6	1.8	-0.4	-2.0	-1.4	-1.0
Loneliness, isolation	0.6	0.8	1.5	1.2	-0.9	0.8	1.0	-1.0	-1.1	-0.4	0.3
Long-standing illness, disability or infirmity	0.4	0.6	1.5	1.2	-0.5	0.2	1.2	-0.2	-1.2	-0.4	-0.6
Ever had bowel cancer screening	0.2	0.2	0.6	0.3	-0.1	0.7	0.7	-0.0	-0.3	-0.3	0.3
Diabetes diagnosed by doctor	1.8	2.9	8.5	-0.3	-2.9	-2.4	-1.0	-0.7	-1.2	2.3	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.7	0.6	-0.0	0.8	-0.9	-0.4	-0.3	-0.4	-0.1
Friendships satisfaction	1.0	1.3	3.3	0.0	-0.8	1.1	1.8	-0.4	-1.6	-0.9	-1.2
Qualifications: nursing, teaching	2.8	4.4	13.3	-1.4	1.4	-0.9	-1.8	3.7	3.5	1.2	0.7
Commuting to job workplace: Walk	0.9	1.0	2.0	0.9	-1.2	-1.4	-0.0	-0.1	0.9	1.2	1.0
Eye problems/disorders: Cataract	0.2	0.2	1.0	-0.6	-0.2	-1.0	0.2	-0.0	-0.6	0.2	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.2	1.8	0.1	1.1	1.2	-0.8	-0.8	-0.7	-0.1
Medication for cholesterol	3.6	5.5	15.5	-1.5	1.0	-2.2	-2.4	2.9	3.9	2.0	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	2.7	0.1	-1.6	-0.9	0.2	-1.6	-1.2	0.4	0.5
Back pain experienced in last month	1.1	1.6	3.3	1.7	-1.8	-0.9	0.5	-1.5	-1.0	0.8	1.2
Mineral and other dietary supplements	0.7	0.9	2.0	-1.0	-1.3	-1.0	-1.4	-0.1	-1.2	0.4	-0.1
Breast cancer (self-reported)	2.5	3.0	7.3	-0.6	2.4	0.3	-2.4	2.7	1.9	-0.0	-1.0
Asthma (self-reported)	0.8	1.5	6.5	0.4	-1.4	-0.3	0.5	-1.5	-2.6	0.4	0.8
Osteoporosis (self-reported)	1.3	1.6	7.9	-0.7	1.5	-0.0	0.6	2.8	1.2	-0.1	-0.2
Osteoarthritis (self-reported)	1.1	1.4	2.2	-1.5	-1.4	-0.9	-1.0	-1.4	-1.3	0.9	0.8
Medication: Aspirin	1.9	2.4	7.3	2.2	-0.7	-0.1	2.7	-1.6	-1.8	-0.6	-0.8
Medication: Gliclazide	0.9	1.0	2.8	1.0	-1.7	-1.4	0.2	-0.6	-0.6	1.0	-0.5
Illnesses of father: None of the above (group 1)	0.9	1.1	3.7	1.1	-0.2	1.9	1.0	-0.7	-0.8	-1.3	-0.5
Smoking status: Current	2.7	4.3	15.7	1.1	-2.0	-0.1	2.1	-2.9	-4.0	-0.5	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	5.9	0.7	2.0	2.0	2.4	-0.1	0.5	-2.3	-1.2
Whole body water mass	0.3	2.0	8.5	-2.9	-1.5	-1.4	0.1	-0.6	-1.0	1.3	-0.4
Leg predicted mass (right)	0.3	1.7	5.6	-2.4	-1.9	-1.0	-0.3	-0.8	-0.9	1.4	-0.1
Arm fat mass (left)	0.1	0.6	1.1	0.8	-0.9	-1.1	0.3	0.0	-0.7	0.7	-0.9
Number of self-reported non-cancer illnesses	1.1	1.8	8.2	0.7	-1.5	0.1	0.7	-1.7	-2.9	0.2	0.2
Average weekly champagne plus white wine intake	0.7	0.9	2.2	0.6	0.9	0.9	-0.0	1.5	0.7	-1.2	-1.2
Miserableness	0.8	1.4	4.0	2.0	-0.4	1.7	1.4	-0.4	-1.2	-1.0	-0.2
Guilty feelings	3.5	5.2	11.3	1.9	3.0	3.0	2.0	0.8	-0.8	-3.4	-2.0
Wears glasses or contact lenses	0.7	0.9	2.5	-0.9	-1.1	0.3	0.3	-1.4	-1.6	0.0	-0.4
Ever taken oral contraceptive pill	1.5	1.7	4.8	1.8	-1.3	0.5	1.2	-2.2	-1.3	-0.4	-0.4
Hearing aid user	1.0	1.1	2.9	-1.7	-0.1	-1.3	-1.7	0.0	0.6	1.1	0.2
Mother’s age at death	1.2	1.5	9.0	-3.0	1.2	0.7	0.2	0.7	0.3	-0.0	0.5
Financial situation satisfaction	1.5	1.9	4.3	-0.3	-0.4	1.2	0.9	-2.1	-1.8	-1.1	-2.0
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.4	1.2	0.4	0.6	0.3	0.5	-0.3	-0.2	0.4
Commuting to job workplace: Public transport	0.6	0.7	2.4	1.0	-0.7	0.7	1.6	-0.9	-0.7	-0.5	0.1
Eye problems/disorders: Glaucoma	0.9	1.1	5.6	-0.5	-0.5	-0.8	-2.4	0.4	0.6	0.9	0.7
Medication: Blood pressure	1.8	3.5	6.3	2.2	-1.0	1.4	1.8	-2.5	-2.4	-1.4	-1.8
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.4	-1.3	-1.7	-0.6	0.0	-1.8	-1.8	0.6	1.1
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.8	0.8	0.5	0.8	1.3	-0.1	0.7	-0.0	0.1
High cholesterol (Self-reported)	0.6	1.1	3.0	-0.0	1.5	-0.7	-1.7	1.3	1.2	0.2	0.4
Medication: Bendroflumethiazide	0.3	0.4	1.9	1.4	-0.4	-0.7	0.4	-0.0	0.1	0.6	-0.4
Medication: Paracetamol	1.1	1.7	4.9	1.6	-1.7	0.1	1.2	-1.2	-2.2	-0.4	-0.2
Medication: Lisinopril	0.5	0.7	2.2	0.9	-1.5	0.1	0.6	-0.6	-1.2	-0.1	-0.6
Medication: Atorvastatin	2.3	2.9	6.0	1.3	2.0	2.0	1.6	-0.4	-0.8	-2.0	-2.5
Illnesses of father: High blood pressure	0.6	0.8	2.5	-0.3	-1.1	-1.6	-0.1	-0.4	0.7	1.1	0.9
Alcohol drinker status: Never	0.7	0.8	2.0	-1.0	0.6	-0.3	-0.5	0.9	1.4	0.0	-1.4
Ever smoked	1.3	2.2	7.5	1.3	-1.5	0.1	0.6	-2.7	-2.2	-0.5	-1.0
Basal metabolic rate	0.3	1.6	5.5	-2.3	-1.6	-1.3	0.1	-0.7	-1.1	1.2	-0.5
Leg fat percentage (left)	0.5	1.9	5.6	2.4	-1.5	-1.0	0.6	-0.9	-1.7	0.4	-1.3
Arm fat-free mass (left)	0.3	1.7	4.4	-2.1	-1.5	-1.1	1.0	-1.1	-1.4	0.8	-0.7
Number of operations (self-reported)	2.1	3.0	11.4	-0.4	-0.1	0.6	0.3	-3.4	-2.3	-0.9	-2.4
Average weekly beer plus cider intake	0.5	0.7	2.3	1.2	0.1	-1.5	-0.5	0.1	0.6	0.9	-0.2
Irritability	0.6	0.9	4.2	2.0	-1.0	0.9	0.6	-0.5	-0.8	-0.4	0.4
Risk taking	2.5	3.6	9.5	0.2	0.1	1.6	3.1	-1.5	-2.5	-1.9	-2.2
Ever had prostate specific antigen (PSA) test	1.1	1.3	3.4	-1.5	1.7	-0.0	0.0	1.0	1.8	-0.0	-0.9
Fractured/broken bones in last 5 years	1.3	1.7	4.3	-1.3	1.5	1.6	0.7	0.3	-0.3	-1.6	-2.1
Age started oral contraceptive pill	3.4	4.2	19.2	0.0	2.3	-0.7	-0.6	2.9	4.4	0.4	0.1
Diastolic blood pressure, automated reading	0.7	2.1	4.5	-0.2	-0.6	-2.1	-0.7	1.5	1.2	2.0	2.0
Ever depressed for a whole week	4.2	5.2	10.6	2.3	-1.3	1.1	2.9	-2.8	-3.3	-1.5	-2.0
Unable to work because of sickness or disability	2.5	3.3	8.7	1.7	-1.7	-1.2	1.3	-2.9	-2.9	-0.2	-0.1
Commuting to job workplace: Cycle	3.2	3.9	13.0	-0.8	3.4	0.8	-0.4	1.9	3.6	-1.3	-0.0
Myopia	1.1	1.6	5.1	0.3	1.3	0.0	-0.1	2.0	2.3	0.1	-1.4
Vascular/heart problems diagnosed by doctor	0.8	2.2	5.0	-2.2	1.8	0.7	-0.9	1.7	2.2	-0.7	0.4
Cholesterol lowering medication	0.2	0.3	0.9	0.9	-0.2	-0.1	-0.4	-0.8	-1.0	-0.2	0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.9	-0.3	-1.4	-0.1	0.4	-1.1	-1.4	0.1	-0.7
Pain experienced in last month	2.5	4.1	9.4	-2.2	1.8	-0.5	-2.5	3.0	3.1	0.3	-0.0
Supplements: Calcium	0.3	0.3	1.1	0.1	0.4	-0.6	0.5	1.0	0.2	0.8	-0.4
Basal cell carcinoma (self-reported)	1.2	1.5	3.3	-0.8	-0.1	-1.6	-0.5	1.8	1.2	1.5	1.1
Heart attack/myocardial infarction (self-reported)	0.4	0.6	1.3	0.9	-1.1	-0.9	0.2	-0.4	-0.4	0.8	0.8
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.2	-1.5	0.5	-0.7	-0.7	1.0	0.3	0.4	1.1
Heart disease (siblings)	0.4	0.5	1.7	0.9	1.3	0.0	0.4	1.0	0.4	-0.1	0.0
Alcohol drinker status: Previous	1.1	1.3	3.6	1.3	-0.0	0.6	1.8	-1.9	-0.6	-0.8	0.6
Pack years of smoking	0.3	0.4	2.0	0.5	-0.5	-0.2	0.2	-0.5	-1.4	-0.1	-0.8
Impedance of whole body	0.4	1.9	4.8	2.2	0.8	1.8	1.4	-0.3	-0.5	-2.0	-0.6
Leg fat mass (left)	0.4	1.5	3.3	1.3	-1.5	-1.0	0.5	-0.9	-1.8	0.5	-1.4
Arm predicted mass (left)	0.4	1.9	5.6	-2.4	-1.6	-1.2	0.7	-1.0	-1.6	0.9	-0.8