[Hub]/) : Traits : Height :

chr2:108,372,251-110,002,052

Best TWAS P=2.63e-12 · Best GWAS P=2.03e-11 conditioned to 0.389

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GCC2 0.12 0.17 enet 30 0.18 5.1e-21 6.2 5.9 3.9e-09 0.91 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous GCC2 0.36 0.46 enet 23 0.45 5.8e-40 -5.9 5.2 2.2e-07 0.61 0.48 0.52 FALSE
3 GTEx Adipose Visceral Omentum GCC2 0.25 0.27 lasso 11 0.22 9.8e-12 -5.7 5.7 1.4e-08 0.69 0.67 0.33 FALSE
4 GTEx Artery Aorta GCC2 0.09 0.03 lasso 11 0.02 3.3e-02 -5.9 5.9 3.8e-09 0.65 0.16 0.53 FALSE
5 GTEx Artery Aorta LIMS1 0.17 0.11 lasso 4 0.10 5.0e-06 -5.6 6.2 5.1e-10 0.68 0.36 0.56 FALSE
6 GTEx Artery Coronary GCC2 0.31 0.26 lasso 4 0.18 8.8e-07 -5.9 5.8 8.0e-09 0.67 0.56 0.44 FALSE
7 GTEx Artery Tibial AC012487.2 0.06 0.03 enet 21 0.01 2.5e-02 6.4 6.2 5.1e-10 0.67 0.05 0.80 FALSE
8 GTEx Brain Cerebellar Hemisphere GCC2 0.22 -0.01 lasso 7 -0.01 8.2e-01 6.2 -5.8 6.2e-09 -0.83 0.03 0.76 FALSE
9 GTEx Brain Cerebellum GCC2 0.17 0.10 enet 16 0.08 2.4e-03 6.4 6.5 1.0e-10 0.94 0.03 0.93 FALSE
10 GTEx Breast Mammary Tissue GCC2 0.31 0.32 lasso 8 0.31 1.6e-16 -5.7 5.5 2.9e-08 0.65 0.68 0.32 FALSE
11 GTEx Breast Mammary Tissue (Female) GCC2 0.28 0.31 lasso 10 0.28 6.4e-09 -5.7 5.7 1.2e-08 0.68 0.64 0.36 FALSE
12 GTEx Cells Transformed fibroblasts GCC2 0.19 0.16 enet 14 0.18 3.4e-13 -5.7 5.7 1.5e-08 0.67 0.66 0.34 FALSE
13 GTEx Esophagus Gastroesophageal Junction GCC2 0.16 0.14 lasso 9 0.12 5.8e-05 -5.7 5.7 9.9e-09 0.68 0.47 0.41 FALSE
14 GTEx Esophagus Gastroesophageal Junction AC012487.2 0.14 0.01 enet 14 0.07 1.7e-03 6.7 5.9 3.4e-09 0.74 0.03 0.79 FALSE
15 GTEx Esophagus Mucosa GCC2 0.24 0.28 enet 22 0.28 3.0e-19 -5.2 6.0 2.4e-09 0.67 0.65 0.35 FALSE
16 GTEx Esophagus Muscularis GCC2 0.18 0.18 lasso 3 0.20 3.8e-12 -5.9 6.1 1.3e-09 0.66 0.59 0.41 FALSE
17 GTEx Esophagus Muscularis LIMS1 0.10 0.00 lasso 3 0.00 2.4e-01 6.0 6.0 2.4e-09 0.87 0.06 0.81 FALSE
18 GTEx Heart Atrial Appendage GCC2 0.14 0.14 lasso 1 0.11 1.5e-05 -5.9 5.9 3.2e-09 0.68 0.43 0.50 FALSE
19 GTEx Lung GCC2 0.21 0.29 lasso 3 0.29 3.7e-22 -5.6 5.6 1.9e-08 0.67 0.66 0.34 FALSE
20 GTEx Muscle Skeletal GCC2 0.05 0.04 lasso 9 0.03 1.2e-03 -5.9 5.6 2.0e-08 0.67 0.41 0.30 FALSE
21 GTEx Nerve Tibial GCC2 0.27 0.28 lasso 10 0.27 2.8e-19 -5.1 6.1 8.1e-10 0.76 0.63 0.37 FALSE
22 GTEx Skin Not Sun Exposed Suprapubic GCC2 0.21 0.30 lasso 4 0.28 8.8e-16 -5.9 6.0 1.6e-09 0.67 0.53 0.47 FALSE
23 GTEx Skin Sun Exposed Lower leg GCC2 0.30 0.29 lasso 10 0.32 3.2e-27 -5.9 5.8 9.2e-09 0.67 0.54 0.46 FALSE
24 GTEx Spleen GCC2 0.41 0.33 lasso 7 0.31 9.9e-09 -5.7 5.7 9.2e-09 0.69 0.63 0.35 FALSE
25 GTEx Stomach GCC2 0.17 0.21 lasso 11 0.22 5.6e-11 -5.7 5.7 1.4e-08 0.69 0.48 0.52 FALSE
26 GTEx Stomach AC012487.2 0.08 0.02 enet 19 0.05 2.2e-03 -5.2 6.9 6.0e-12 0.82 0.04 0.93 FALSE
27 GTEx Thyroid GCC2 0.24 0.19 enet 27 0.19 3.1e-14 -5.7 5.1 2.9e-07 0.63 0.67 0.33 FALSE
28 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma LIMS1 0.02 0.01 blup 54 0.02 4.1e-03 -5.8 -6.5 9.9e-11 -0.87 0.03 0.77 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma LIMS1 0.03 0.01 blup 54 0.03 4.4e-04 6.7 7.0 2.6e-12 0.91 0.02 0.95 TRUE