Best TWAS P=2.49e-11 · Best GWAS P=3.85e-11 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | BCL2L11 | 0.04 | 0.04 | lasso | 2 | 0.03 | 0.0002 | 6.6 | -6.7 | 2.5e-11 | -1.00 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | BCL2L11 | 0.07 | 0.01 | blup | 71 | 0.06 | 0.0002 | -5.7 | -6.0 | 2.0e-09 | -0.85 | 0.02 | 0.95 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BCL2L11 | 0.04 | 0.02 | lasso | 3 | 0.02 | 0.0057 | 5.5 | -6.3 | 2.8e-10 | -0.61 | 0.05 | 0.26 | FALSE |