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chr2:113,218,247-115,210,760

Best TWAS P=4.61e-12 · Best GWAS P=1.1e-10 conditioned to 0.00947

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	RABL2A	0.11	0.00	lasso	4	0.02	4.0e-02	-5.8	-5.5	3.2e-08	0.79	0.05	0.39	FALSE
2	GTEx	Adrenal Gland	PSD4	0.16	0.02	enet	26	0.02	5.9e-02	4.2	5.3	1.0e-07	-0.03	0.08	0.06	FALSE
3	GTEx	Artery Aorta	SLC35F5	0.09	0.04	enet	8	0.07	1.5e-04	4.6	-6.8	1.3e-11	0.42	0.04	0.83	FALSE
4	GTEx	Artery Aorta	PAX8	0.39	0.40	enet	18	0.41	2.4e-24	4.2	-5.3	1.2e-07	0.08	0.99	0.01	FALSE
5	GTEx	Artery Coronary	PAX8	0.29	0.16	enet	26	0.07	2.7e-03	-3.8	-5.2	2.3e-07	0.08	0.64	0.02	FALSE
6	GTEx	Artery Tibial	SLC35F5	0.15	0.11	enet	12	0.10	2.9e-08	4.6	-5.8	5.1e-09	0.24	0.98	0.01	FALSE
7	GTEx	Brain Hypothalamus	PAX8	0.35	0.24	enet	26	0.20	1.9e-05	4.2	-5.2	2.3e-07	0.04	0.24	0.07	FALSE
8	GTEx	Cells Transformed fibroblasts	SLC35F5	0.12	0.04	enet	24	0.07	2.9e-06	4.6	-6.1	1.4e-09	0.32	0.33	0.08	FALSE
9	GTEx	Colon Transverse	AC016683.6	0.34	0.13	enet	20	0.32	8.7e-16	4.2	-5.1	2.9e-07	0.07	0.99	0.01	FALSE
10	GTEx	Pituitary	AC016683.6	0.46	0.28	enet	18	0.34	1.9e-09	4.2	-5.1	3.0e-07	0.09	0.58	0.04	FALSE
11	GTEx	Skin Sun Exposed Lower leg	RABL2A	0.10	0.05	enet	12	0.05	3.4e-05	-3.4	-5.2	1.5e-07	0.59	0.79	0.15	FALSE
12	GTEx	Small Intestine Terminal Ileum	WASH2P	0.28	0.04	lasso	7	0.05	3.6e-02	-5.8	6.4	2.0e-10	-0.71	0.04	0.19	FALSE
13	GTEx	Stomach	AC016683.6	0.42	0.18	enet	50	0.26	9.0e-13	4.2	-5.2	1.8e-07	0.04	0.99	0.01	FALSE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ACTR3	0.05	0.02	lasso	4	0.02	1.3e-02	-6.0	6.5	1.1e-10	-0.50	0.00	0.89	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	ACTR3	0.02	0.03	lasso	2	0.02	8.7e-06	-6.3	6.3	2.2e-10	-0.42	0.00	1.00	FALSE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC654433	0.25	0.18	blup	60	0.20	1.2e-11	4.2	-5.2	1.8e-07	0.07	0.03	0.84	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PAX8	0.14	0.16	enet	9	0.16	3.1e-17	4.2	-5.1	2.7e-07	0.09	0.03	0.84	FALSE
18	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PAX8	0.12	0.05	enet	11	0.07	3.5e-04	-3.5	-6.0	2.4e-09	0.10	0.03	0.56	TRUE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	DDX11L2	0.14	0.08	lasso	3	0.11	6.2e-13	-5.8	5.1	2.9e-07	-0.76	0.00	1.00	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DDX11L2	0.12	0.11	enet	5	0.13	3.1e-14	-5.8	5.4	6.7e-08	-0.79	0.00	1.00	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	ACTR3	0.06	0.00	enet	17	0.03	3.8e-04	-5.4	6.8	1.5e-11	-0.54	0.01	0.64	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	ACTR3	0.10	0.05	lasso	4	0.04	1.2e-04	-6.3	6.9	4.6e-12	-0.54	0.00	0.99	TRUE