Best TWAS P=5.74e-28 · Best GWAS P=1.87e-29 conditioned to 0.000434
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 10.9 | -11 | 5.7e-28 | -0.86 | 0.03 | 0.57 | TRUE |
| 2 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 7.4 | 8 | 1.9e-15 | 0.65 | 0.05 | 0.68 | FALSE |
| 3 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 10.5 | -11 | 2.9e-27 | -0.83 | 0.11 | 0.89 | FALSE |