Hub : Genes

STON1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.4310	0.0580	0.0e+00	0.242	0.264	0.303	0.321	0.293	4.3e-29	4.7e-32	2.2e-37	5.5e-40	6.1e-36
2	GTEx	Brain Cortex	0.4020	0.0890	1.3e-05	0.232	NA	0.208	NA	0.197	4.6e-07	NA	2.1e-06	NA	4.0e-06
3	GTEx	Brain Nucleus accumbens basal ganglia	0.2310	0.0920	9.0e-03	0.015	NA	0.014	NA	0.060	1.3e-01	NA	1.4e-01	NA	1.0e-02
4	GTEx	Brain Putamen basal ganglia	0.4600	0.1240	1.4e-03	0.144	NA	0.076	NA	0.138	2.8e-04	NA	7.4e-03	NA	3.8e-04
5	GTEx	Colon Sigmoid	0.4610	0.0900	2.6e-06	0.161	NA	0.201	NA	0.241	2.6e-06	NA	1.2e-07	NA	4.7e-09
6	GTEx	Esophagus Gastroesophageal Junction	0.4100	0.1100	1.3e-04	0.422	NA	0.357	NA	0.414	1.2e-16	NA	8.9e-14	NA	2.7e-16
7	GTEx	Esophagus Mucosa	0.0860	0.0370	5.0e-03	0.139	NA	0.089	NA	0.128	1.4e-09	NA	1.5e-06	NA	6.9e-09
8	GTEx	Esophagus Muscularis	0.5070	0.0730	5.0e-16	0.446	NA	0.395	NA	0.433	1.2e-29	NA	1.7e-25	NA	1.7e-28
9	GTEx	Lung	0.1172	0.0476	3.4e-03	0.061	NA	0.022	NA	-0.003	1.9e-05	NA	8.1e-03	NA	7.0e-01
10	GTEx	Nerve Tibial	0.1872	0.0696	4.1e-03	0.095	NA	0.081	NA	0.079	3.2e-07	NA	2.4e-06	NA	3.2e-06
11	GTEx	Whole Blood	0.0660	0.0270	5.6e-03	0.004	NA	-0.003	NA	0.001	1.1e-01	NA	8.4e-01	NA	2.3e-01
12	METSIM	Adipose	0.0592	0.0197	1.6e-04	0.003	0.033	0.008	0.033	0.006	8.8e-02	8.2e-06	1.9e-02	9.3e-06	3.1e-02
13	ROSMAP	Brain Pre-frontal Cortex	0.4809	0.0496	0.0e+00	0.208	0.329	0.367	0.363	0.338	2.9e-26	1.6e-43	1.8e-49	7.0e-49	6.0e-45
14	YFS	Blood	0.0882	0.0200	1.1e-12	0.016	0.048	0.041	0.048	0.044	4.3e-06	2.0e-15	1.8e-13	1.5e-15	3.4e-14
15	TCGA	Breast Invasive Carcinoma	0.0597	0.0238	1.5e-05	0.019	0.033	0.025	NA	0.028	8.0e-05	1.9e-07	5.4e-06	NA	1.8e-06
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0905	0.0452	1.1e-05	0.023	0.026	0.044	NA	0.054	1.1e-03	6.1e-04	8.8e-06	NA	1.0e-06
17	TCGA	Pancreatic Adenocarcinoma	0.1500	0.0700	8.7e-03	0.034	0.049	0.042	NA	0.031	1.5e-02	4.2e-03	7.5e-03	NA	1.8e-02
18	TCGA	Thyroid Carcinoma	0.1030	0.0410	1.7e-04	0.037	0.030	0.039	NA	0.047	1.5e-04	5.6e-04	9.4e-05	NA	2.2e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Bipolar Disorder (2018)	1.4	2.2	7.3	1.3	-0.5	1.2	-0.8	-2.6	-2.4	-2.4	-2.3	0.4	-0.8	-0.7	0.4	0.5	-0.7	-2.7	-0.6	-1.3	0.8
Bipolar Disorder or Schizophrenia	0.6	1.5	7.1	1.7	1.4	2.7	1.0	-0.3	0.8	0.8	0.8	-0.9	-0.1	-0.3	2.5	1.4	0.2	-0.7	0.7	0.9	1.4
Depressed Affect (Nagel 2018)	1.1	2.2	10.3	-1.9	-2.0	-2.4	-2.1	0.2	-0.5	-0.5	-0.6	1.5	0.4	-1.5	0.4	-2.1	0.2	-0.7	-1.1	-0.1	-3.2
Depression (Nagel 2018)	1.1	1.6	10.9	-1.3	-1.3	-0.8	-1.0	-0.3	-0.3	-0.3	-0.4	-0.2	-0.3	-0.9	-1.5	-2.8	-0.6	-1.1	-0.3	-0.6	-3.3
Intelligence (Savage-Jansen 2018)	0.5	1.6	4.0	2.0	1.9	1.6	1.9	1.1	0.5	0.5	0.7	-1.1	0.6	-0.5	-0.5	0.9	1.6	0.8	2.0	-1.8	0.3
Neuroticism (Nagel 2018)	1.2	2.9	8.9	-1.5	-2.7	-2.3	-3.0	-0.0	-1.2	-1.2	-1.4	2.9	0.4	-0.4	1.0	-1.9	0.6	-1.0	-2.3	0.6	-1.8
Schizophrenia (2018)	1.6	3.4	8.3	1.2	2.2	0.6	2.0	1.8	2.9	2.9	2.9	-1.5	0.3	0.2	2.8	1.4	0.8	1.3	1.4	2.1	1.1
Schizophrenia vs Biploar Disorder	2.2	2.9	7.5	-0.7	2.0	-0.9	2.3	1.9	2.0	2.0	2.1	-2.2	-1.1	0.9	1.2	-0.6	0.9	2.7	2.4	1.6	-0.9
Worry (Nagel 2018)	1.0	2.1	6.0	-0.8	-2.4	-0.9	-2.2	-0.6	-1.7	-1.7	-1.8	2.4	1.0	-0.1	0.8	-1.1	0.9	-0.7	-2.5	0.5	-0.1
Alzheimer’s Disease (in mother)	1.8	2.1	4.7	0.2	-2.1	-1.4	-1.4	-1.6	-2.2	-2.2	-2.2	1.4	0.5	-0.5	-0.3	0.1	-1.7	-1.1	-2.0	-0.2	1.4
Alzheimer’s Disease (in father)	1.7	1.9	8.0	1.6	1.3	1.1	1.1	1.9	1.3	1.3	1.4	-0.7	-0.6	1.5	2.8	1.0	1.4	0.6	1.6	1.1	0.1
Alzheimer’s Disease (including proxy)	0.6	0.8	3.8	0.7	-0.9	-0.6	-0.7	-0.4	-0.9	-0.9	-0.9	0.4	-0.8	1.4	1.9	-0.2	-1.3	-0.3	-0.7	0.7	0.5
Crohns Disease (2017)	1.1	2.3	9.6	2.2	0.6	1.6	1.4	-1.3	-1.7	-1.7	-1.5	-1.1	-0.8	1.6	-1.8	0.7	0.8	-2.0	0.6	-3.1	-0.0
Irritable Bowel Disease (IBD)	0.8	2.0	6.4	1.3	-0.3	0.8	1.1	-1.5	-2.1	-2.1	-1.9	-0.8	-0.8	1.9	-0.7	0.3	0.8	-2.1	0.9	-2.5	-0.3
Ulcerative Colitis (UC)	0.5	1.0	2.9	-0.0	-1.2	-0.1	0.0	-1.5	-1.6	-1.6	-1.5	-0.1	-0.8	1.0	0.1	-0.3	-0.2	-1.7	0.4	-0.9	-0.4
Major Depression (MDD)	1.4	1.7	6.5	1.0	0.8	-1.1	0.1	2.6	1.8	1.8	1.7	0.0	1.5	-0.9	0.5	1.3	0.7	1.9	0.4	0.4	1.0
Reaction Time	1.2	2.3	9.8	-2.5	-1.2	-2.1	-2.4	-0.1	0.5	0.5	0.2	0.9	0.3	-0.4	0.3	-2.3	-3.1	-0.1	-1.0	1.1	-2.1
Verbal and Numeric Reasoning (VNR)	0.8	1.8	4.9	2.2	2.2	1.9	2.2	1.2	0.9	0.9	1.1	-0.9	-0.3	0.2	-0.0	1.4	1.4	0.9	1.3	-0.4	1.6
Breast Cancer	0.7	1.7	4.8	2.2	1.0	1.9	1.5	-1.5	-0.2	-0.2	-0.1	-0.5	-2.2	-1.6	-1.8	0.9	-0.3	-0.9	0.4	0.2	1.8
Ovarian Cancer	2.1	2.8	8.9	-0.1	0.3	-0.0	-0.6	1.8	2.7	2.7	2.5	1.7	1.5	0.5	2.2	-0.2	0.7	1.6	-0.9	3.0	1.4
Prostate Cancer	1.2	1.7	7.0	0.1	1.4	0.1	0.3	1.9	2.6	2.6	2.6	0.0	-0.0	-0.1	1.6	0.2	0.5	0.8	0.6	0.9	0.0
Age at First Birth	1.1	1.7	5.5	1.4	0.9	1.0	0.6	-1.5	0.2	0.2	0.2	-0.6	-1.7	2.4	2.0	0.6	-2.0	0.8	1.2	0.2	2.1
Bipolar Disorder (2011)	0.4	0.4	4.1	0.5	0.3	-0.2	0.5	-0.2	0.0	-0.2	-0.2	-0.4	-0.6	-0.4	0.5	0.3	0.5	0.5	-0.2	0.8	2.0
Body Mass Index (BMI) (2010)	0.7	1.0	5.8	-1.3	-0.6	0.3	-0.7	-0.6	0.1	0.1	0.0	-0.8	-0.9	0.3	-0.5	-2.4	-1.0	-0.1	0.9	-0.1	-2.3
Coronary Artery Disease (CAD)	1.1	1.3	10.7	-0.5	-0.6	-0.8	-1.2	0.1	0.9	0.9	0.7	1.0	0.8	3.3	1.3	-0.8	-0.6	0.3	-1.3	1.0	0.2
Crohns Disease (2012)	1.2	1.9	7.4	2.7	1.3	1.8	1.9	-0.3	-0.7	-0.7	-0.5	-1.2	-0.3	2.1	-0.8	1.3	1.2	-1.0	0.8	-2.5	0.3
Mean Putamen Volume	0.5	0.6	2.7	-0.3	-0.7	-0.1	-0.7	-0.5	-0.8	-0.8	-0.8	-0.6	-1.6	1.4	-0.2	0.5	0.8	0.9	-0.6	0.0	-0.2
Fasting Glucose	1.0	1.2	5.7	-1.4	-0.5	-1.0	-0.0	-0.7	0.9	0.9	0.7	-0.3	-0.4	1.3	0.2	-1.7	-2.2	-0.4	-0.5	2.4	-0.1
HbA1C	0.5	0.6	2.4	0.7	0.6	0.7	0.8	0.5	0.4	0.4	0.4	-1.5	-0.5	1.0	-1.1	-0.1	-0.4	-0.1	0.1	1.2	1.3
HDL Cholesterol	0.9	1.6	3.9	1.4	1.6	1.5	1.6	1.4	1.2	1.2	1.3	0.2	-1.3	-0.8	2.0	1.2	0.5	0.7	0.8	1.1	1.6
LDL Cholesterol	0.7	1.1	2.3	0.6	1.2	1.4	-0.0	0.7	1.5	1.5	1.5	-0.3	0.7	0.8	0.1	0.9	-1.4	0.7	0.5	1.2	1.5
Lupus	1.1	1.7	5.8	-0.4	-1.9	-2.4	-1.8	-1.1	-1.8	-1.8	-1.8	1.5	1.0	0.2	0.6	-1.1	-0.0	-0.4	-1.4	-0.5	-0.6
Neuroticism (2016)	0.5	0.7	2.4	-1.5	-1.0	-1.2	-1.2	0.0	-0.3	-0.3	-0.3	0.5	0.6	-0.6	-0.1	-1.5	1.1	-0.0	-0.6	-0.1	-1.0
Primary Biliary Cirrhosis	0.4	0.6	3.4	0.4	0.1	1.3	-0.2	0.4	-0.4	-0.4	-0.4	0.3	-0.5	-0.5	1.8	0.8	1.3	-0.6	0.2	-1.0	-0.1
Rheumatoid Arthritis	1.0	1.4	3.9	-1.4	0.8	0.0	0.0	1.4	1.8	1.8	1.8	-0.6	-0.7	0.4	0.1	-0.9	0.3	2.0	1.3	1.8	-0.2
Schizophrenia (2014)	1.9	4.2	9.5	1.6	2.9	1.1	2.6	2.0	2.8	2.8	2.9	-1.9	-0.4	-0.1	3.1	1.4	1.7	1.3	1.8	2.0	1.3
Triglycerides	0.7	1.1	6.1	-1.2	0.0	-0.3	-1.2	-0.8	0.6	0.6	0.5	-0.0	0.6	-0.7	-2.5	-0.7	-1.9	-0.6	0.4	0.5	-1.9
Type 2 Diabetes (T2D) (2012)	1.3	1.4	5.2	1.0	1.6	1.8	1.8	-0.1	1.2	1.2	1.3	-1.1	0.7	2.3	-0.8	0.8	-0.7	0.4	1.6	-0.1	-0.2
Ulcerative Colitis	0.5	0.7	2.0	0.6	-0.1	0.6	1.0	-0.6	-1.2	-1.2	-1.0	-0.8	-0.6	0.7	-0.6	0.0	1.1	-1.2	0.8	-1.4	-0.4
Blood Eosinophil Count	0.1	0.9	4.2	-0.4	-0.2	-0.2	0.4	-0.4	-0.9	-0.9	-0.8	-0.9	-0.6	-0.9	-2.0	1.3	1.4	-0.4	-0.4	-1.6	-0.5
Blood Platelet Count	0.5	5.5	31.6	-2.4	-0.7	-1.4	0.0	-2.4	-2.5	-2.5	-2.3	-2.1	-0.3	-0.9	-5.6	-2.2	-1.0	-0.1	1.5	-3.1	-3.5
Blood Red Count	0.2	1.9	6.6	1.7	1.8	1.0	1.5	0.7	1.6	1.6	1.6	0.4	-0.5	-0.5	0.9	1.8	1.0	1.2	0.8	1.7	2.6
Blood White Count	0.6	4.3	19.9	-0.5	0.7	1.1	2.5	-1.3	-1.4	-1.4	-1.1	-3.5	0.8	-0.8	-4.5	-0.2	-0.2	-1.6	1.7	-4.2	-2.7
Heel T-Score	0.1	0.8	3.3	0.2	-0.2	-0.4	0.1	1.0	0.1	0.1	0.1	0.8	1.2	-0.0	-1.8	0.2	1.8	1.3	1.0	1.1	0.4
BMI	0.4	2.6	11.8	-2.5	-0.8	-1.6	-0.7	0.1	0.2	0.2	0.2	-0.7	-0.2	-2.5	-3.4	-2.8	-0.5	-0.5	-0.3	-0.2	-3.1
Height	0.2	3.3	22.4	2.8	1.9	1.1	1.5	0.3	-0.1	-0.1	0.1	-0.6	0.3	3.0	4.7	2.1	2.1	0.5	0.7	-1.4	-1.2
Waist Hip Ratio (WHR)	0.8	3.6	9.5	-0.3	-1.5	-2.1	-1.2	-1.3	-2.0	-2.0	-2.0	0.6	3.1	-2.5	-2.4	2.2	1.8	0.6	-1.9	-3.0	-0.3
Systolic Blood Pressure	0.2	0.9	3.3	-1.0	-0.4	-1.3	-0.7	0.3	-0.5	-0.5	-0.5	-0.0	0.5	1.8	1.3	-1.6	-0.3	-0.2	-0.0	-0.4	-1.8
Smoking Status	1.1	2.7	9.3	-0.6	2.4	0.3	2.5	1.4	1.3	1.3	1.5	-3.1	-1.6	-1.9	-0.0	-0.7	0.1	0.8	2.4	-0.7	-2.5
Allergy or Eczema	0.3	0.7	3.8	1.2	0.6	-0.5	0.2	-0.1	0.6	0.6	0.5	1.0	-0.0	-1.2	0.2	1.9	0.4	0.6	-0.7	0.8	1.1
Cardiovascular Disease	1.1	3.7	11.2	-2.5	-2.5	-2.1	-1.9	-1.2	-1.7	-1.7	-1.8	0.1	1.6	-0.2	-3.1	-3.3	-1.5	-0.4	-1.1	-1.3	-2.7
Hypothyroidism (self reported)	1.0	2.2	9.9	-1.3	-2.6	-1.4	-2.1	-0.5	-1.1	-1.1	-1.3	2.7	0.7	-0.3	-1.2	-0.6	-0.5	0.6	-3.1	-0.2	0.4
Respiratory disease	1.1	2.3	8.0	0.4	1.3	0.7	1.3	2.0	2.6	2.6	2.5	-1.4	-0.3	-0.3	-0.5	0.0	-0.0	1.5	0.8	2.8	1.3
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.5	-0.3	0.3	-0.4	-0.2	-0.2	0.8	0.8	0.7	-0.2	-0.1	-1.4	-1.6	0.3	-0.7	-0.5	0.5	0.5	-1.4
Lung FEV1/FVC ratio	1.3	6.4	25.4	0.3	-2.8	-1.2	-3.0	-3.3	-2.9	-2.9	-3.0	1.5	-1.4	-5.0	-3.4	-0.1	-1.4	-2.3	-3.2	-1.2	0.4
Lung FVC	2.3	11.7	45.0	0.6	3.6	2.2	3.0	3.2	5.2	5.2	5.1	-2.1	-1.4	-0.2	1.5	0.3	-0.1	3.6	3.4	6.7	4.1
Neuroticism	1.1	2.6	7.0	-2.1	-2.2	-2.6	-2.6	0.7	-0.5	-0.5	-0.7	2.2	0.6	0.0	1.1	-2.4	1.2	-0.2	-1.9	0.3	-2.4
Chronotype (morning person)	4.8	11.0	30.2	-3.4	-5.4	-2.7	-5.5	-3.8	-4.1	-4.1	-4.4	4.1	0.1	1.3	0.2	-3.9	-0.7	-0.5	-4.0	0.7	0.4
Hair Pigment	0.0	1.3	3.3	1.0	1.8	1.1	1.5	1.0	1.4	1.4	1.5	-0.2	0.1	-0.4	0.6	0.5	1.7	0.6	1.0	1.6	-0.1
Tanning	0.0	0.3	2.8	-0.3	-0.1	-0.4	-0.3	-0.1	-0.6	-0.6	-0.6	0.0	-0.3	0.9	1.7	-0.5	0.2	0.4	-0.0	-0.0	-0.2
Hand grip strength (left)	1.0	2.7	10.7	0.4	1.7	0.0	1.3	1.3	2.4	2.4	2.4	-0.9	-0.8	2.6	1.8	-0.3	-0.9	0.5	1.0	3.3	1.2
Number of treatments/medications taken	0.6	1.1	4.2	-1.7	-1.7	-1.6	-1.4	0.6	0.6	0.6	0.4	0.8	-0.3	0.1	-0.0	-2.0	-0.4	0.7	-0.5	1.5	-0.7
Average weekly spirits intake	1.0	1.2	3.3	-0.2	0.6	0.7	0.9	1.2	1.0	1.0	1.0	-0.8	1.4	-0.2	-0.1	-1.3	1.3	1.8	1.5	0.9	-1.8
Sensitivity / hurt feelings	2.3	3.9	14.5	-1.0	-2.5	-2.2	-3.5	-0.2	-0.8	-0.8	-1.1	3.7	-1.0	-0.3	1.6	-1.3	-1.1	-0.9	-3.8	2.3	1.2
Frequency of depressed mood in last 2 weeks	0.9	1.2	7.5	-1.2	-0.6	-1.2	-0.5	0.3	0.2	0.2	0.1	0.0	0.3	-0.5	-1.3	-2.6	-0.7	-1.0	-0.8	-0.7	-2.7
Hearing difficulty/problems: Yes	0.3	0.5	3.7	-0.2	-0.0	1.1	-0.3	-0.5	0.4	0.4	0.4	-0.9	0.1	-0.8	-1.9	-0.3	-0.6	0.4	-0.5	-0.4	-0.5
Relative age of first facial hair	0.6	1.3	5.6	-0.7	-1.3	-0.9	-0.8	-1.5	-1.1	-1.1	-1.2	1.3	-0.7	-0.3	-2.4	-1.6	-1.1	-0.4	-1.1	-0.1	-0.7
Other serious medical condition/disability diagnosed by doctor	1.6	2.1	4.9	-2.1	-2.2	-2.2	-2.2	-0.7	-0.5	-0.5	-0.6	1.6	-0.6	-2.1	-0.6	-1.8	-0.0	0.8	-1.6	1.9	-0.4
Ever used hormone-replacement therapy (HRT)	1.7	2.2	14.8	-0.6	-0.1	-0.7	0.1	2.1	0.2	0.2	0.2	-0.7	2.1	-3.8	-0.9	0.3	2.2	0.6	1.0	0.1	-2.6
Ever had hysterectomy (womb removed)	5.1	5.8	33.4	-2.3	-2.0	-1.5	-1.3	-2.5	-2.4	-2.4	-2.5	0.1	0.3	-3.4	-5.8	-2.4	-1.7	-1.8	-1.7	-1.7	-1.8
Systolic blood pressure, automated reading	0.3	1.0	3.9	-1.2	-0.6	-1.3	-0.4	-0.2	-0.8	-0.8	-0.8	0.2	-0.4	1.5	1.5	-1.8	-0.3	-0.4	-0.4	-0.2	-2.0
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	2.1	0.2	0.4	-0.3	0.1	1.0	1.0	1.0	1.0	0.7	-0.2	-1.3	0.3	0.1	0.5	0.5	-0.1	1.5	0.7
Angina	1.2	1.6	4.1	-1.5	-0.0	-2.0	0.2	1.6	1.2	1.2	1.1	-1.5	1.2	-1.7	-1.7	-0.9	0.4	1.3	0.4	0.5	-1.8
Medication for hormone replacement therapy	2.4	2.7	13.5	0.0	1.7	-0.3	1.9	2.2	1.1	1.1	1.2	-2.5	0.5	-0.8	0.2	-0.0	2.2	0.8	2.5	-1.0	-3.7
Vitamin and mineral supplements	1.3	1.8	16.2	0.9	0.8	0.2	1.3	0.5	-0.5	-0.5	-0.4	-1.4	0.5	4.0	0.5	0.8	-0.3	-0.3	0.8	-2.5	-0.8
Supplements: Zinc	1.3	1.4	3.3	-1.6	-1.8	0.3	-1.7	-1.2	-1.3	-1.3	-1.4	1.4	0.1	1.1	-0.4	-1.1	-1.4	-0.8	-1.2	0.2	0.1
Medication: Co-codamol	0.9	1.0	3.8	-0.6	0.2	-0.4	0.1	1.7	1.5	1.5	1.4	0.1	2.0	0.5	1.1	0.0	-0.2	0.5	1.1	0.9	-0.6
Medication: Metformin	0.4	0.6	2.8	-0.2	-0.2	-1.7	-0.1	0.5	1.0	1.0	0.9	0.6	0.5	0.2	-0.6	-0.0	0.1	0.6	0.9	1.6	0.1
Diabetes (father)	1.4	1.7	5.4	0.3	1.6	0.8	0.6	1.9	2.3	2.3	2.3	0.7	1.3	-1.1	0.5	0.9	0.3	0.5	0.7	1.5	-0.1
Diabetes (mother)	0.9	1.2	2.5	-0.7	-0.2	0.3	0.7	-0.8	-1.2	-1.2	-1.2	-1.1	-1.4	1.5	-1.5	-0.2	-1.4	-0.9	-0.2	-1.6	-1.3
Severe depression (siblings)	0.7	0.8	6.6	0.8	0.6	0.1	1.2	1.0	0.5	0.5	0.6	-0.6	0.1	-0.9	0.7	2.6	1.2	0.5	0.2	0.5	0.0
Pack years adult smoking proportion	0.4	0.7	3.3	0.4	-0.1	0.2	0.1	-0.1	0.4	0.4	0.5	-0.8	0.5	-0.7	-1.6	-0.7	-1.1	-0.4	-0.3	-1.4	-1.8
Impedance of leg (right)	0.4	2.0	6.7	-0.6	-0.9	-1.4	-1.2	-0.6	-1.7	-1.7	-1.6	2.6	2.5	0.1	2.2	1.0	1.4	-0.4	-0.9	-0.7	0.1
Leg fat-free mass (left)	0.3	1.5	4.8	0.3	1.1	0.5	1.1	1.0	1.7	1.7	1.6	-1.9	-0.4	-0.1	-1.8	-1.3	-0.6	-0.3	1.0	0.2	-2.2
Trunk fat percentage	0.5	1.8	12.6	-1.9	0.1	-1.9	0.2	1.6	0.3	0.3	0.4	-0.1	1.8	-0.2	-1.0	-1.1	1.9	-0.5	-0.6	-0.8	-3.5
Hand grip strength (right)	1.4	3.8	9.4	1.1	2.4	0.8	1.8	1.6	2.8	2.8	2.8	-1.3	-0.6	3.0	2.2	0.1	-1.5	0.6	1.3	3.1	1.8
Townsend deprivation index at recruitment	1.1	1.6	7.2	-1.7	0.1	-1.2	0.5	0.5	-0.2	-0.2	-0.1	-1.9	0.0	-1.3	-1.5	-1.9	-0.2	1.3	1.4	-1.3	-2.7
Current tobacco smoking	0.8	1.3	6.2	-0.7	0.9	-0.3	1.1	0.1	-0.4	-0.4	-0.2	-1.4	-1.1	-2.5	-1.6	0.1	0.6	0.5	0.7	-2.0	-2.0
Average weekly fortified wine intake	1.2	1.4	5.1	1.2	1.1	0.4	0.7	1.4	1.2	1.2	1.2	-1.3	0.1	-1.1	-1.9	0.2	0.8	2.3	0.8	0.9	0.8
Maternal smoking around birth	0.8	1.1	8.7	-1.4	-0.4	-1.5	0.2	0.6	-0.2	-0.2	-0.2	-1.4	0.6	-1.1	-0.6	-1.5	0.1	-0.3	0.3	-0.2	-2.9
Fed-up feelings	1.4	2.5	13.9	-2.0	-2.0	-1.9	-1.8	-0.4	-1.3	-1.3	-1.3	0.6	0.4	-0.5	-0.1	-2.6	-0.9	-1.3	-0.8	-1.1	-3.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	5.6	-0.4	-1.0	-1.0	-1.0	0.7	-0.2	-0.2	-0.2	-0.1	0.4	-1.3	-1.6	-1.6	-0.3	-0.3	-0.4	-0.9	-2.4
Relative age voice broke	0.1	0.2	0.6	0.3	-0.0	-0.1	-0.1	0.6	0.6	0.6	0.5	0.8	-0.4	-0.1	-0.2	0.4	0.2	0.2	-0.4	0.7	0.5
Taking other prescription medications	0.8	1.2	4.5	-1.0	-2.1	-0.8	-1.7	0.6	-0.2	-0.2	-0.3	1.8	0.7	0.6	-0.8	-1.3	0.5	0.1	-1.9	1.2	0.2
Age when periods started (menarche)	0.8	2.0	13.5	1.6	-0.5	-2.1	-1.1	-0.8	0.2	0.2	0.1	1.3	-0.5	1.7	1.9	0.3	0.8	0.6	-2.0	0.8	3.7
Bilateral oophorectomy (both ovaries removed)	4.7	5.4	12.1	-1.9	-2.7	-2.7	-3.0	-3.1	-2.8	-2.8	-2.9	0.3	-1.0	-2.2	-3.5	-2.4	-1.8	-0.0	-1.7	-0.3	-2.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	5.3	-0.8	-0.5	0.0	0.4	-0.7	-0.7	-0.7	-0.7	-0.5	0.3	-0.5	-2.3	-1.3	-0.3	-0.4	0.8	-0.7	-0.4
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	4.3	1.0	0.0	0.4	-0.6	-0.8	-0.4	-0.4	-0.4	-0.0	-2.1	0.1	0.8	0.3	0.1	-0.1	0.1	-0.2	-0.2
Qualifications: CSEs or equivalent	0.7	0.9	4.5	-1.8	-0.3	-0.6	-0.3	0.6	0.6	0.6	0.6	0.1	1.4	-0.1	-2.1	-1.7	0.2	0.9	-0.2	0.8	-0.8
Serious illness, injury or assault to yourself	0.3	0.4	1.8	0.5	0.5	0.9	-0.1	0.3	0.3	0.3	0.3	0.2	0.9	-0.4	-1.0	1.3	-0.1	-0.3	-0.7	-0.2	1.0
High blood pressure	0.4	1.1	9.0	-1.1	-0.7	-1.2	-1.0	0.0	-0.4	-0.4	-0.5	-0.3	0.2	-0.8	-1.1	-1.3	-0.7	-0.6	-0.1	-0.9	-3.0
Hayfever, allergic rhinitis or eczema	0.2	0.4	3.1	1.0	0.4	-0.1	0.2	-0.5	0.0	0.0	0.0	0.5	-0.3	-0.8	-0.1	1.8	-0.3	0.7	-0.2	0.6	1.0
Multivitamins +/- minerals	1.4	1.7	15.4	-0.8	-0.5	0.0	-1.5	0.3	0.8	0.8	0.7	1.9	0.0	-3.9	0.1	-0.2	1.1	0.5	-0.7	2.2	0.2
Stomach or abdominal pain in last month	1.6	1.9	11.0	-0.0	0.7	1.1	1.0	-0.7	0.5	0.5	0.6	-2.5	-1.1	-2.5	-3.3	-1.0	-1.5	-0.3	1.8	0.4	-0.0
Supplements: Glucosamine	0.9	1.2	6.6	-0.0	-0.8	-0.7	-1.6	0.6	0.0	0.0	-0.1	1.7	-0.1	-0.8	0.5	0.2	0.2	1.2	-0.8	2.6	2.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.3	-1.1	-1.5	-0.3	-0.6	-1.0	-0.7	-0.7	-0.7	0.3	-0.4	-0.9	-1.4	-1.0	-0.7	-1.2	-1.1	0.8	0.3
Medication: Atenolol	0.5	0.7	1.9	0.1	0.7	0.8	0.3	0.7	1.3	1.3	1.2	-0.6	0.7	-1.4	-0.5	0.5	0.3	-0.5	0.7	0.3	-1.1
Medication: Levothyroxine sodium	1.0	1.8	5.1	-1.5	-2.3	-1.7	-1.5	-0.9	-1.1	-1.1	-1.2	2.0	1.1	0.5	-0.8	-2.0	-0.5	-0.2	-1.9	-0.4	-0.6
Sitting height	0.2	1.4	4.9	1.8	2.0	1.1	2.2	-0.6	0.8	0.8	0.9	-1.2	1.1	0.0	-0.8	1.1	0.1	-0.9	1.2	-1.3	-0.9
Chronic bronchitis/emphysema (father)	0.7	0.9	3.3	-1.1	-1.5	-1.8	-1.5	0.2	-0.5	-0.5	-0.6	1.2	1.0	-0.9	0.5	-0.1	0.0	0.1	-1.1	0.5	-0.9
High blood pressure (mother)	1.0	1.4	5.8	-2.0	-1.7	-1.0	-0.3	-1.4	-1.0	-1.0	-1.0	0.1	-0.4	2.0	-0.6	-2.4	-0.5	-0.4	-0.2	0.4	-1.5
Body mass index (BMI)	0.4	1.5	9.2	-1.9	-0.3	-0.7	-0.3	0.6	0.5	0.5	0.4	-0.9	0.2	-0.8	-2.5	-2.1	-0.3	-0.7	0.0	-0.4	-3.0
Impedance of leg (left)	0.3	1.7	4.2	-0.4	-0.4	-0.7	-0.7	-0.8	-1.7	-1.7	-1.6	1.9	2.1	0.4	1.9	1.4	1.7	-0.8	-0.8	-1.4	-0.3
Leg predicted mass (left)	0.3	1.4	4.8	0.2	1.0	0.4	1.0	0.9	1.6	1.6	1.5	-1.8	-0.4	-0.2	-1.9	-1.4	-0.7	-0.3	0.9	0.2	-2.2
Trunk fat mass	0.4	1.8	15.0	-1.7	0.3	-1.5	0.3	1.3	0.6	0.6	0.6	-0.6	1.2	-0.1	-1.5	-1.6	1.2	-0.6	-0.1	-0.6	-3.9
Waist circumference	0.4	1.3	7.4	-1.6	-0.8	-2.0	-1.1	0.5	0.3	0.3	0.2	0.2	1.3	-0.9	-1.5	-1.0	0.6	0.1	-0.8	-0.3	-2.7
Number of incorrect matches in round	0.2	0.3	2.4	0.2	0.2	-0.2	-0.4	0.2	0.4	0.4	0.4	-0.3	1.5	-0.5	0.5	0.4	-0.0	0.8	0.5	0.0	-1.1
Past tobacco smoking	1.0	1.8	3.9	1.1	-1.6	0.7	-1.4	-1.7	-1.8	-1.8	-1.8	1.9	0.1	1.2	0.3	1.0	0.3	-0.3	-1.7	-1.1	2.0
Alcohol usually taken with meals	0.4	0.6	4.7	0.6	-0.2	-0.1	-0.7	-0.5	0.4	0.4	0.2	1.4	-0.1	-0.5	1.3	0.4	-0.4	-0.3	-0.3	0.8	2.2
Nervous feelings	0.7	1.4	5.7	-0.1	-1.8	-1.1	-1.3	-0.1	-1.2	-1.2	-1.2	2.3	1.4	0.2	-0.1	0.2	1.0	-0.2	-2.4	-0.1	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	8.0	0.5	0.1	-0.6	0.1	1.0	0.5	0.5	0.5	-0.3	1.0	-2.8	-0.8	-0.2	1.3	-1.0	-0.0	-1.3	-2.2
Hearing difficulty/problems with background noise	0.3	0.5	1.1	0.6	-0.8	0.9	-0.7	-1.0	-0.7	-0.7	-0.7	-0.1	-0.5	1.1	-0.8	-0.8	-0.4	-0.4	-0.4	-0.5	-0.7
Hair/balding pattern: Pattern 2	0.8	1.0	3.7	-1.4	0.5	0.4	0.3	0.4	1.4	1.4	1.3	-0.4	-0.1	-0.6	-0.2	-1.3	-1.0	-0.3	1.1	1.9	-1.0
Had menopause	0.3	0.3	2.7	0.3	0.1	1.0	-0.2	0.9	-0.1	-0.1	-0.1	-0.2	-0.3	-0.3	1.6	0.3	0.8	0.2	-0.3	-0.1	-0.5
Had other major operations	1.7	2.1	8.3	-0.9	-1.3	-0.5	-1.4	-2.1	-1.2	-1.2	-1.2	-0.0	-0.8	-2.7	-2.9	-1.1	-2.3	-1.0	-1.1	-0.2	0.2
Forced vital capacity (FVC)	1.4	5.5	11.3	1.2	3.4	1.6	3.3	2.5	3.1	3.1	3.2	-1.7	0.9	0.6	1.2	1.4	1.3	2.6	3.0	3.0	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	4.7	-1.0	-0.8	-0.1	0.0	-0.9	-1.0	-1.0	-0.9	-0.8	0.8	-1.1	-2.2	-1.1	-0.8	-0.5	0.9	-0.8	-0.7
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.5	-0.3	-1.3	0.0	-0.7	-0.7	-0.7	-0.7	-0.7	0.9	-0.9	-1.5	-0.7	-0.5	-1.2	0.3	-1.9	0.1	1.3
Qualifications: None of the above	1.1	2.3	6.7	-2.5	-2.6	-2.2	-1.9	-0.4	-1.4	-1.4	-1.5	0.3	0.3	2.0	0.7	-1.3	-0.2	1.8	-0.7	1.6	0.5
Financial difficulties in last 2 years	1.0	1.3	4.3	0.7	1.6	1.0	2.0	0.8	0.2	0.2	0.4	-1.4	-0.0	-0.6	-1.9	0.9	0.1	-0.5	0.2	-2.1	-1.8
Mouth/teeth dental problems	0.9	1.4	5.2	1.7	1.4	1.0	1.4	-0.4	-0.8	-0.8	-0.6	-1.1	-2.3	1.5	0.6	1.6	-0.4	-0.1	0.8	-1.1	1.2
Heart attack	0.6	0.7	2.4	-1.3	-0.1	-0.9	0.0	-0.0	0.3	0.3	0.3	-1.2	-0.5	-1.1	-1.5	-1.6	-0.5	0.2	0.9	0.7	-1.0
Allergy	0.4	1.0	4.7	-0.2	-0.4	0.2	-0.0	-0.9	-1.2	-1.2	-1.2	-0.0	0.4	1.4	-0.1	-1.0	-0.6	-2.0	-0.0	-2.2	-0.9
Pain all over the body in last month	0.8	0.9	5.4	-1.0	-0.9	-0.6	-0.3	1.1	0.8	0.8	0.7	-0.1	1.2	-0.8	-1.2	-0.2	0.2	1.0	0.3	2.3	0.7
Diabetes (self-reported)	0.2	0.3	1.2	0.2	-0.2	0.1	-0.4	-0.4	0.8	0.8	0.7	0.5	-0.5	-1.1	-0.8	0.4	-0.5	-0.5	-0.2	0.9	0.1
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.6	1.9	1.6	1.4	1.3	1.1	1.3	1.3	1.3	-0.1	-0.3	-0.9	0.0	1.4	1.6	0.5	0.4	0.6	0.6
Medication: Ramipril	0.5	0.6	2.0	-0.7	0.8	1.4	0.3	0.6	1.1	1.1	1.1	-0.7	0.7	-0.9	-0.4	-0.3	-0.7	-0.1	0.2	0.6	-1.2
Medication: Simvastatin	1.7	2.6	11.3	-1.4	-1.6	-0.8	-1.3	-1.6	-0.7	-0.7	-0.8	-0.8	-0.4	-0.1	-3.2	-3.4	-2.1	-1.1	-0.6	-0.9	-2.6
Fluid intelligence score	0.6	1.1	5.8	2.0	1.1	1.9	1.4	0.5	0.5	0.5	0.6	-0.4	-0.3	-0.6	-0.3	1.3	0.6	0.7	0.4	-0.2	2.4
Illnesses of siblings	0.3	0.4	2.6	0.2	0.1	-0.7	0.3	-0.0	-0.5	-0.5	-0.4	0.1	-0.1	-0.1	1.6	0.8	0.5	0.5	-0.7	-0.5	1.5
Neuroticism score	1.5	3.2	9.4	-1.8	-2.4	-3.0	-3.1	0.9	-0.1	-0.1	-0.4	2.8	0.7	0.0	1.3	-2.4	0.8	-0.2	-2.6	1.0	-2.0
Weight	0.3	1.4	12.3	-0.8	0.5	-0.4	0.4	0.8	0.9	0.9	0.9	-1.0	0.4	-0.1	-1.7	-1.8	0.1	-1.0	0.5	-0.4	-3.5
Impedance of arm (right)	0.6	2.7	13.7	-0.1	0.2	-2.4	0.4	1.5	-0.4	-0.4	-0.2	2.0	2.4	-0.7	2.5	2.2	3.7	1.6	-1.3	-0.3	0.7
Arm fat percentage (right)	0.5	1.9	10.0	-2.2	-0.1	-1.9	-0.2	1.6	0.8	0.8	0.8	-0.2	1.4	-1.3	-1.7	-1.5	1.3	-0.1	-0.3	-0.1	-3.2
Trunk fat-free mass	0.2	1.1	2.8	0.7	0.8	1.1	0.7	-0.0	1.4	1.4	1.3	-1.7	-0.8	0.8	-1.1	-1.1	-1.4	-0.5	0.9	0.5	-1.4
Hip circumference	0.3	1.2	6.7	-0.7	0.5	-0.6	0.3	1.4	1.6	1.6	1.5	-0.1	0.1	0.3	-0.2	-1.9	0.3	-0.6	0.2	0.7	-2.6
Time employed in main current job	0.9	1.0	7.2	1.4	0.8	-0.4	0.2	0.1	0.6	0.6	0.6	0.7	-0.4	0.5	2.7	0.8	-0.3	0.5	0.3	1.4	1.9
Alcohol intake versus 10 years previously	0.4	0.5	2.8	-0.3	-0.8	-0.6	-0.4	-0.3	-0.5	-0.5	-0.4	0.7	0.8	0.0	-0.3	0.4	0.3	-0.8	0.1	-1.7	-1.6
Father’s age at death	0.8	1.1	6.7	1.4	0.5	0.5	0.5	0.9	0.7	0.7	0.7	-0.9	-0.1	2.6	1.7	0.2	1.0	1.0	0.9	-0.7	0.9
Worrier / anxious feelings	2.1	3.9	11.7	-1.4	-2.6	-2.5	-3.2	0.5	-1.6	-1.6	-1.7	3.4	1.1	1.5	3.1	-1.0	0.6	0.5	-2.9	1.0	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	6.6	-0.5	0.2	-0.3	0.2	1.2	0.8	0.8	0.8	-0.6	-0.0	-0.5	-0.8	-1.5	0.1	-0.2	1.0	0.0	-2.6
Falls in the last year	0.4	0.5	3.5	-0.5	-1.4	-0.3	-0.8	0.2	-0.3	-0.3	-0.3	0.0	-0.1	-1.9	-0.4	-1.1	0.2	-0.3	-0.4	0.5	-0.1
Hair/balding pattern: Pattern 3	0.4	0.6	4.0	0.2	-0.1	0.3	-0.6	0.5	0.6	0.6	0.5	-0.3	-1.4	0.3	2.0	-0.0	0.2	0.7	-0.9	1.3	0.5
Number of live births	0.6	0.8	7.1	0.5	-0.3	-0.1	-0.7	0.5	-0.0	-0.0	-0.1	-0.6	-0.2	-2.7	-1.2	-0.5	0.2	-1.7	-0.2	0.6	-0.7
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	5.5	0.7	2.1	1.1	2.0	1.0	1.8	1.8	1.8	-1.1	0.2	-0.4	-0.2	0.8	0.3	1.5	1.8	2.3	1.3
Pulse rate	1.2	2.1	8.4	-0.1	-1.3	0.8	-1.5	-1.2	-0.9	-0.9	-1.0	0.5	-2.5	-1.8	-2.9	-0.5	-1.7	0.8	-0.7	1.6	1.8
Happiness	3.2	3.8	21.0	-2.0	-2.2	-2.5	-2.3	-0.4	-0.6	-0.6	-0.7	1.0	-0.3	-4.6	-2.7	-3.4	-0.8	0.6	-1.9	0.5	-1.1
Noisy workplace	2.4	2.9	11.0	-2.7	-2.2	-3.3	-2.2	-0.5	-1.5	-1.5	-1.6	0.5	0.7	-0.1	-2.2	-2.4	-1.2	1.8	-0.9	-0.2	-1.1
Qualifications: A levels/AS levels or equivalent	1.3	2.9	13.0	3.6	1.9	3.3	1.8	0.2	-0.4	-0.4	-0.2	-0.6	-0.4	0.3	-0.2	3.3	0.6	-1.5	1.1	-2.0	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.8	0.5	0.1	0.6	0.9	-0.6	-0.6	-0.6	-0.5	-0.0	0.1	0.4	-0.8	0.1	0.8	-0.7	0.1	-0.6	0.3
Mouth/teeth dental problems: Dentures	0.7	1.2	5.6	-1.4	-1.3	-1.1	-1.3	-0.2	1.0	1.0	0.8	0.3	0.1	-0.8	-0.2	-2.4	-0.2	0.0	-0.8	2.2	-0.4
Asthma	0.7	1.3	4.7	0.4	0.4	0.6	0.8	1.5	1.8	1.8	1.7	-0.7	-0.6	-1.2	-0.3	-0.5	0.0	1.1	0.4	2.2	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	3.8	0.7	-0.6	0.3	-0.6	1.4	0.5	0.5	0.4	1.6	1.9	-0.6	1.4	0.5	1.2	0.2	-0.9	0.2	1.4
Medication: Cholesterol lowering	0.9	1.4	5.3	-1.7	-1.9	-1.6	-2.0	-0.6	-0.3	-0.3	-0.5	0.3	-0.2	0.2	-1.2	-2.3	-1.5	0.0	-1.3	0.8	-0.1
Depression (self-reported)	0.5	0.6	4.2	0.3	-0.4	-1.1	0.0	-0.1	-0.3	-0.3	-0.3	0.2	0.6	-1.1	-2.0	-0.3	0.2	-0.5	-1.3	-1.2	-0.6
Medication: Lansoprazole	0.2	0.2	1.8	0.1	0.5	0.8	0.7	0.3	-0.0	-0.0	0.1	-0.1	0.5	0.2	-0.1	0.2	-0.2	0.2	1.3	0.3	-0.4
Prospective memory result	0.9	1.0	5.9	-0.9	-1.4	-1.0	-1.5	0.6	0.5	0.5	0.3	1.4	2.4	0.2	1.3	-0.2	0.2	0.5	-1.0	1.1	-0.3
Lung cancer (father)	0.5	0.6	3.6	0.6	-0.2	0.8	0.5	-0.1	-0.5	-0.5	-0.4	-1.0	-1.1	-0.4	-1.9	0.4	0.1	-0.4	-0.2	-1.5	0.0
Illnesses of mother	2.5	3.1	10.5	1.6	2.5	0.8	1.2	3.2	2.4	2.4	2.4	-1.8	1.8	-1.3	-0.4	1.6	1.8	0.9	1.2	-0.7	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.3	8.2	0.7	2.4	1.0	2.1	2.1	2.8	2.8	2.7	-1.3	0.4	-0.5	0.0	0.7	0.7	1.7	2.3	2.9	1.1
Pulse wave Arterial Stiffness index	0.7	0.8	6.6	-0.7	0.3	-1.3	-0.4	-0.9	-0.2	-0.2	-0.1	-1.1	-1.0	-0.9	-2.6	-0.1	-0.4	0.1	0.3	-0.2	-1.3
Impedance of arm (left)	0.5	2.5	13.8	0.5	0.8	-1.6	0.7	1.5	-0.7	-0.7	-0.5	1.7	1.9	-0.5	2.8	2.6	3.7	1.2	-0.8	-0.7	0.7
Arm fat mass (right)	0.4	1.6	11.0	-1.6	0.3	-0.9	0.3	1.2	0.9	0.9	0.8	-0.9	1.1	-0.8	-2.2	-1.7	0.6	-0.5	0.2	-0.3	-3.3
Trunk predicted mass	0.2	1.1	2.5	0.6	0.7	1.1	0.6	-0.0	1.4	1.4	1.3	-1.6	-0.8	0.7	-1.2	-1.1	-1.4	-0.5	0.8	0.5	-1.4
Standing height	0.1	1.3	3.9	1.9	2.0	0.6	1.8	0.5	1.1	1.1	1.1	-0.8	0.4	1.4	1.1	0.6	0.9	-0.3	1.2	-0.3	-1.4
Length of working week for main job	0.4	0.4	2.3	-0.6	-0.5	-0.2	0.3	0.4	-0.7	-0.7	-0.7	-0.0	0.6	-0.5	-0.1	-0.3	0.7	-0.5	0.1	-1.2	-1.5
Exposure to tobacco smoke at home	0.8	0.9	6.7	-1.1	-0.5	-0.1	0.7	-0.2	-0.5	-0.5	-0.4	-0.7	1.7	-2.6	-1.0	0.4	1.0	0.0	0.4	-1.2	-0.6
Breastfed as a baby	0.7	0.9	7.5	-0.2	-0.7	-0.1	-1.1	-0.3	0.1	0.1	-0.0	1.3	-0.9	-0.8	0.1	-1.4	-0.7	-0.5	0.5	2.7	0.8
Tense / ‘highly strung’	0.4	0.6	2.2	-0.3	-0.6	-0.3	-0.9	0.8	-0.2	-0.2	-0.2	0.8	1.4	-0.1	1.3	0.4	1.5	-0.5	0.1	-0.7	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.5	0.6	-0.3	-0.1	-0.2	0.9	0.1	0.1	0.1	0.0	1.0	-0.3	0.7	0.5	0.5	-0.9	-0.6	-0.5	-1.2
Hair/balding pattern: Pattern 4	1.2	3.0	16.5	2.1	-0.0	1.3	1.2	-0.4	-2.0	-2.0	-1.8	-0.7	1.1	-0.1	-1.5	2.3	2.6	-0.3	0.1	-4.1	1.4
Birth weight of first child	0.6	1.2	9.4	0.2	0.0	-0.8	-0.1	0.3	1.2	1.2	1.1	-0.3	-1.0	-0.2	-0.8	-1.1	-0.6	0.7	0.4	3.1	1.7
Peak expiratory flow (PEF)	1.0	2.4	8.6	0.9	2.0	0.8	1.8	1.3	2.0	2.0	2.0	-0.4	0.1	-0.3	-0.5	1.4	-0.2	1.4	0.4	2.9	2.7
Pulse wave reflection index	0.6	0.8	2.7	0.5	1.4	-0.7	1.0	0.4	0.6	0.6	0.8	-1.6	-0.0	1.1	0.7	0.3	0.7	1.1	1.1	-0.5	-0.6
Ever highly irritable/argumentative for 2 days	1.0	1.2	4.3	-0.6	0.6	-1.2	0.4	0.2	1.1	1.1	1.1	-1.8	-2.1	-0.9	-0.5	-1.9	-0.7	0.5	0.1	0.5	-1.4
Loud music exposure frequency	1.1	1.2	4.4	0.9	0.4	1.0	1.4	0.3	-0.4	-0.4	-0.2	-0.9	-1.6	-2.1	-0.4	0.9	1.2	1.3	0.2	0.6	2.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	2.0	1.0	0.5	1.4	0.8	0.4	0.5	0.5	0.4	0.1	-0.5	0.2	-0.3	0.7	0.0	-1.2	-0.5	-0.3	-0.0
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	5.2	-1.0	-0.9	-0.9	-0.8	-0.6	0.3	0.3	0.1	1.4	2.3	-0.8	-1.4	-0.8	-1.4	-0.6	-0.6	0.7	-0.3
Blood clot in the leg (DVT)	0.8	1.0	3.3	-1.1	-0.8	-0.2	-1.1	1.3	1.4	1.4	1.3	0.1	-0.3	-0.4	0.1	-1.2	0.2	1.4	-0.5	1.8	-0.6
Medication: Paracetamol	1.2	2.0	7.1	-0.6	-0.8	0.4	-1.4	1.8	1.8	1.8	1.6	2.7	1.1	0.2	2.3	-0.5	0.5	0.5	-0.7	2.4	0.3
Headache pain in last month	2.4	4.2	11.4	2.2	1.4	0.2	0.9	3.4	2.1	2.1	2.2	0.8	1.1	-1.8	2.2	2.9	3.4	2.0	1.1	1.1	2.5
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	4.7	1.5	1.3	1.9	1.8	-0.5	-0.7	-0.7	-0.5	-1.2	-0.2	0.2	0.7	1.8	1.0	-0.6	2.0	-2.2	-0.7
Glaucoma (self-reported)	1.3	1.5	7.1	2.7	1.1	1.1	1.7	0.7	0.2	0.2	0.3	-0.2	0.3	0.2	0.0	2.2	2.6	-0.3	0.4	-1.5	0.1
Gout (self-reported)	0.5	0.7	4.3	-0.7	0.3	0.9	0.6	0.5	-0.4	-0.4	-0.2	-0.1	0.8	0.3	0.2	-0.8	2.1	-1.0	-0.1	-1.4	-1.3
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	7.8	-1.1	-2.7	-1.6	-2.1	-1.0	-1.4	-1.4	-1.6	2.8	0.7	0.5	-0.7	-1.4	-0.4	-0.2	-2.7	-0.2	0.3
Medication: Amlodipine	1.0	1.4	6.6	0.4	1.4	-0.7	0.7	2.6	1.4	1.4	1.4	-0.0	1.4	1.0	0.7	1.5	1.4	1.3	0.4	-0.0	-1.0
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.0	0.3	-0.8	-0.2	-0.3	0.6	-0.2	-0.2	-0.2	0.4	0.3	-1.3	0.1	-1.4	0.1	-0.6	-0.8	0.4	-0.1
Birth weight	1.2	2.7	7.4	-0.7	-0.8	0.4	-0.3	-1.8	-2.7	-2.7	-2.6	-0.0	-1.2	0.9	-1.6	-1.5	0.5	-2.3	-0.7	-1.7	-2.5
Chronic bronchitis/emphysema (mother)	1.5	1.8	6.0	-1.5	-2.0	-1.8	-2.4	-0.5	-0.6	-0.6	-0.7	2.4	0.4	-1.3	1.2	-0.4	0.2	0.3	-2.0	0.8	1.0
High blood pressure (siblings)	0.8	1.1	3.0	0.3	1.2	1.6	0.6	-0.1	1.2	1.2	1.1	-1.4	-1.7	0.3	-0.8	-0.7	-0.8	-0.4	0.9	0.8	-1.7
Forced vital capacity (FVC), Best measure	1.7	6.3	14.4	1.3	3.5	1.6	3.1	3.0	3.8	3.8	3.8	-1.8	0.5	-0.1	1.0	1.2	1.4	2.2	3.2	3.3	1.4
Body fat percentage	0.5	2.1	15.0	-2.3	-0.2	-2.1	-0.5	1.3	0.2	0.2	0.2	0.1	1.8	-0.7	-1.3	-1.5	1.4	-0.7	-0.5	-0.7	-3.9
Leg fat percentage (right)	0.8	3.1	20.2	-2.9	-1.4	-1.9	-1.9	0.2	-0.9	-0.9	-0.9	0.8	1.6	-0.6	-1.5	-2.3	0.4	-1.3	-0.5	-1.0	-4.5
Arm fat-free mass (right)	0.3	1.5	4.0	0.6	1.0	1.5	0.8	-0.1	1.2	1.2	1.2	-1.9	-0.8	1.2	-1.6	-1.4	-1.4	-1.2	1.2	-0.1	-2.0
Exposure to tobacco smoke outside home	0.6	0.8	6.4	-0.3	1.1	-0.0	1.0	0.2	0.8	0.8	0.9	-1.1	0.0	-2.5	-0.3	0.6	0.8	0.9	0.4	-0.3	-0.5
Comparative body size at age 10	0.3	1.0	5.4	-1.7	-0.8	-1.1	-0.3	0.0	0.2	0.2	0.1	-0.2	-2.3	0.1	-1.8	-1.5	-0.8	0.5	-0.4	0.6	-0.4
Number of full brothers	1.0	1.2	4.5	-0.2	1.3	0.8	1.4	0.5	1.4	1.4	1.5	-1.7	-0.6	-0.9	-0.6	-1.0	0.3	0.2	2.1	1.1	0.0
Worry too long after embarrassment	1.8	3.0	10.1	-1.3	-1.0	-1.7	-1.9	2.3	1.6	1.6	1.3	3.2	0.9	0.6	1.9	-1.2	1.4	0.7	-2.4	2.8	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	7.4	1.9	0.3	0.2	-0.1	-0.1	-0.4	-0.4	-0.3	-0.7	-0.1	-2.0	-1.0	-0.0	-0.9	-2.7	-0.2	-2.1	-2.0
Wheeze or whistling in the chest in last year	0.4	0.6	3.5	-0.8	-0.5	0.7	-0.7	-0.3	-0.5	-0.5	-0.5	0.2	-0.5	-0.5	-0.1	-1.8	0.4	-0.6	-0.8	-0.0	-1.9
Number of children fathered	1.8	2.0	7.3	0.9	1.5	0.4	1.7	2.1	1.2	1.2	1.3	-1.2	0.5	2.2	2.7	1.4	1.8	0.2	0.8	-0.1	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	5.3	0.5	2.0	0.1	1.9	1.5	1.0	1.0	1.1	-1.3	1.5	-0.3	-0.4	2.3	0.3	1.7	1.2	0.1	-0.3
Age at first live birth	0.8	1.4	5.6	1.2	-0.4	-0.2	-0.7	-0.6	-0.5	-0.5	-0.6	2.0	-1.0	0.9	2.3	1.8	0.4	0.4	-1.2	-0.1	2.4
Pulse wave peak to peak time	0.9	1.0	7.8	0.7	-0.3	1.3	0.4	1.1	0.4	0.4	0.3	1.1	1.2	1.0	2.8	0.2	0.5	-0.1	-0.3	0.4	1.4
Health satisfaction	1.9	2.5	7.6	-2.8	-2.4	-1.4	-1.4	-0.5	-1.6	-1.6	-1.6	0.6	-0.2	-2.7	-2.0	-2.2	0.2	0.7	-0.5	-0.3	-1.6
Shortness of breath walking on level ground	1.1	1.3	4.6	-0.8	0.8	0.1	0.9	-0.6	0.8	0.8	0.9	-1.6	-1.4	-0.9	-1.5	-2.1	-1.4	-0.4	1.2	-0.4	-1.4
Qualifications: College or University degree	1.6	5.1	27.0	5.2	2.9	4.1	2.1	0.5	0.9	0.9	1.0	-0.6	-0.2	-2.5	0.5	3.3	1.0	-1.8	0.9	-1.4	2.6
Eye problems/disorders: None of the above	0.7	0.8	4.2	-2.0	-0.3	-1.2	-0.4	-0.3	-0.7	-0.7	-0.6	-0.1	-0.2	-0.0	1.9	0.5	0.3	1.9	0.0	0.3	-0.5
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.1	-0.4	0.8	-0.2	0.6	-0.5	-0.7	-0.7	-0.5	-0.6	0.7	-1.4	-1.0	1.1	-0.2	1.0	1.0	-0.6	-0.2
Emphysema/chronic bronchitis	1.7	1.9	6.4	-0.7	1.6	-0.2	0.4	1.4	2.1	2.1	2.1	-1.4	-0.9	0.5	1.0	-0.4	0.0	2.0	0.9	2.5	-0.1
Medication for pain relief, constipation, heartburn	1.6	2.7	15.2	0.9	1.1	0.6	1.1	-2.6	-2.1	-2.1	-1.8	-2.2	-3.9	-0.0	-0.5	0.9	-0.7	-0.3	0.7	-2.2	-0.4
Neck or shoulder pain in last month	0.4	0.5	3.4	-0.8	-0.4	-0.3	-0.3	-0.0	-0.0	-0.0	-0.1	-0.9	0.4	-0.7	0.4	-0.7	0.0	-1.8	-0.4	-0.7	-1.5
Medication: Blood pressure	0.5	0.9	3.4	-1.1	-0.1	-1.3	-0.9	1.1	1.1	1.1	0.9	0.7	0.4	-1.2	-0.2	-0.8	-0.5	0.6	-1.1	1.8	-0.1
Angina (self-reported)	1.3	1.7	4.8	-1.6	0.1	-2.2	0.2	1.6	1.4	1.3	1.2	-1.4	1.2	-1.5	-1.7	-1.0	0.4	1.3	0.5	0.7	-1.8
Migraine (self-reported)	1.1	1.4	5.5	0.6	-0.2	0.2	-0.5	1.5	1.0	1.0	0.9	1.3	2.4	-0.4	1.4	1.9	1.6	0.7	-0.9	1.2	1.2
Medication: Ibuprofen	0.6	0.7	2.1	0.1	-1.2	-0.2	-0.8	0.8	-0.4	-0.4	-0.4	1.4	1.0	-0.6	1.4	-0.2	1.5	-0.2	-0.8	-0.3	0.9
Medication: Allopurinol	0.6	0.8	2.7	-0.6	-0.1	1.2	0.7	0.4	-0.4	-0.4	-0.3	0.6	1.5	1.0	0.5	-1.2	1.6	-0.8	-0.5	-1.4	-1.0
Medication: Omeprazole	1.0	1.2	6.7	-0.1	0.3	-0.7	0.1	1.5	1.5	1.5	1.5	0.5	2.6	-0.0	1.3	0.4	0.5	1.1	0.2	1.2	1.0
Medication: Seretide 50 evohaler	0.6	0.7	2.9	-1.0	-1.1	-0.5	-0.5	-0.3	-0.7	-0.7	-0.7	-0.2	-0.4	-0.4	-0.2	-1.0	-1.3	-1.1	-0.6	-0.9	-1.7
Mean time to correctly identify matches	0.5	1.0	3.5	-1.4	-0.1	-1.5	-0.9	0.8	0.8	0.8	0.7	0.5	0.0	0.1	1.2	-1.1	-1.7	0.8	-0.1	0.7	-1.9
Heart disease (mother)	0.5	0.6	2.8	-0.3	-0.9	-0.5	-0.8	-1.2	-0.9	-0.9	-0.9	1.7	0.1	-0.6	0.0	-0.5	-0.0	-0.9	-0.5	-0.3	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.2	2.6	8.3	-0.6	-2.0	-1.4	-2.1	-1.2	-1.6	-1.6	-1.8	2.9	-0.4	-1.1	-0.6	0.5	-1.2	-0.3	-2.5	1.2	2.4
Whole body fat mass	0.5	2.0	16.6	-1.9	-0.0	-1.6	-0.1	0.9	0.4	0.4	0.4	-0.6	1.2	-0.6	-2.0	-2.0	0.6	-0.9	-0.1	-0.7	-4.1
Leg fat mass (right)	0.7	2.6	20.1	-2.5	-0.8	-1.5	-1.1	0.1	-0.2	-0.2	-0.3	-0.1	1.1	-0.9	-2.2	-2.6	-0.1	-1.6	-0.1	-0.8	-4.5
Arm predicted mass (right)	0.3	1.5	4.3	0.5	1.0	1.4	0.8	-0.0	1.2	1.2	1.1	-2.1	-0.7	1.0	-1.7	-1.2	-1.5	-1.0	1.2	0.0	-2.0
Pulse rate, automated reading	1.4	4.5	11.3	0.0	-2.6	-0.5	-2.6	-2.4	-2.5	-2.5	-2.6	2.0	-1.2	-2.2	-3.4	0.1	-2.0	0.5	-3.1	0.7	2.6
Alcohol intake frequency.	0.6	1.4	5.2	-0.4	-1.8	-1.6	-0.6	-1.0	-0.6	-0.6	-0.7	1.8	-0.3	-0.6	-1.5	-0.6	-0.3	-0.4	-2.1	0.8	2.3
Comparative height size at age 10	0.1	0.5	1.8	-0.3	0.2	0.5	0.4	-0.0	-0.5	-0.5	-0.5	-1.0	-1.4	1.3	-0.6	-1.0	-0.2	-0.3	0.3	0.5	-1.2
Number of full sisters	1.5	1.9	5.6	-2.4	-0.8	-1.0	-1.4	1.7	0.5	0.5	0.4	1.0	1.9	-2.3	-0.1	-0.6	1.6	1.7	-0.7	0.7	-2.0
Suffer from ‘nerves’	0.6	0.9	3.8	-0.6	-1.5	-0.2	-0.7	0.0	-0.4	-0.4	-0.5	1.7	1.6	-0.2	0.3	-0.7	0.5	-0.3	-1.9	1.1	1.0
Overall health rating	1.3	2.7	15.1	-2.6	-1.3	-1.9	-1.3	0.7	-0.3	-0.3	-0.3	0.8	1.0	-2.3	-2.2	-2.4	0.7	0.2	-0.5	0.0	-3.9
Chest pain or discomfort	1.0	1.4	9.1	-1.3	-0.3	0.1	0.4	1.2	0.1	0.1	0.2	-0.7	1.5	-1.7	-1.2	-0.9	1.9	0.5	0.2	-0.8	-3.0
Had major operations	0.9	1.0	5.2	-0.1	-2.3	-1.9	-1.1	-0.3	-1.1	-1.1	-1.1	1.5	0.6	-0.3	0.2	0.0	0.3	-0.7	-1.0	0.5	0.3
Age at last live birth	0.7	1.0	5.1	0.4	-0.7	-0.5	-1.2	-0.2	-0.7	-0.7	-0.7	1.7	-1.7	-0.1	2.3	1.1	1.0	0.1	-0.8	0.5	1.0
Family relationship satisfaction	4.6	5.6	27.1	-2.9	-3.2	-2.4	-3.7	-0.8	-0.8	-0.8	-1.0	3.0	1.2	-5.2	-1.1	-2.6	-1.0	0.7	-3.0	1.7	-1.0
Leg pain on walking	1.7	2.1	13.2	-2.3	-2.1	-1.9	-1.7	-0.8	-1.0	-1.0	-1.2	0.5	-0.2	-0.3	-0.8	-3.6	-0.9	0.4	-1.1	0.3	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.9	0.2	1.0	0.4	0.1	0.7	0.8	0.8	0.9	-0.2	-0.8	-0.3	-0.1	-0.5	0.1	0.1	-0.1	0.9	-0.2
Commuting to job workplace: Car/motor vehicle	0.5	0.6	4.5	0.0	0.0	-0.4	-0.1	0.9	1.1	1.1	1.0	0.2	-0.1	-0.0	2.1	0.0	0.4	-0.2	-0.5	1.1	-0.0
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	6.9	-1.9	-2.6	-1.8	-2.5	-1.9	-1.6	-1.6	-1.8	1.7	-0.2	-0.3	0.7	-2.4	-1.6	-0.2	-1.7	1.5	0.7
Medication: Aspirin	0.6	0.8	3.9	-2.0	-1.1	-1.0	-0.3	1.0	0.4	0.4	0.3	0.4	1.3	-0.1	-1.0	-1.3	-0.0	0.3	0.6	1.3	-0.9
Supplements: Vitamin C	0.8	0.9	3.2	0.2	0.5	1.1	0.3	-0.1	1.2	1.2	1.1	-0.2	0.8	-1.8	-1.3	0.8	-0.6	-0.4	0.2	1.5	1.1
Knee pain experienced in last month	0.9	1.4	5.5	-1.5	-0.8	-1.3	-0.7	1.5	1.0	1.0	0.9	-0.4	-0.0	0.9	1.3	-1.8	0.3	1.5	0.5	2.3	-0.5
Hypertension (Self-reported)	0.6	1.7	10.9	-1.6	-1.2	-1.5	-1.4	-0.7	-1.0	-1.0	-1.1	-0.0	-0.0	-0.3	-1.3	-2.0	-1.0	-0.8	-0.3	-1.2	-3.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	3.5	-1.4	0.2	-1.1	0.4	0.8	1.1	1.1	1.0	-0.5	1.9	1.3	0.8	-0.3	0.2	0.4	-0.0	0.2	-0.9
Illnesses of father: Heart disease	0.5	0.7	2.0	-0.5	-0.8	-0.5	-0.8	0.2	-0.8	-0.8	-0.8	1.1	1.2	-1.4	-0.7	-0.3	1.0	-1.4	-0.3	-0.1	-0.8
Illnesses of siblings: Diabetes	0.6	0.8	2.2	-1.3	-0.9	-0.8	-1.2	0.8	0.0	0.0	-0.0	1.5	1.5	-0.4	-1.0	-0.5	0.3	1.3	-0.0	0.6	-0.9
Smoking status: Previous	1.0	1.5	3.3	-1.2	1.2	-0.7	1.1	1.7	1.8	1.8	1.8	-1.2	0.6	0.2	1.1	-0.6	-0.2	0.4	1.5	1.2	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.5	0.0	0.9	-0.6	1.2	0.2	0.6	0.6	0.6	-0.8	0.4	1.2	-0.9	-0.3	0.1	0.9	0.1	-0.6	-1.0
Whole body fat-free mass	0.2	1.4	4.0	0.6	1.0	1.1	0.9	0.3	1.5	1.5	1.4	-2.0	-0.7	0.5	-1.6	-1.2	-1.3	-0.7	0.9	0.1	-1.9
Leg fat-free mass (right)	0.3	1.9	5.1	0.6	1.5	1.0	1.5	1.0	1.9	1.9	1.8	-2.2	-0.9	0.1	-1.9	-1.1	-0.6	-0.4	1.1	0.1	-2.1
Arm fat percentage (left)	0.4	1.6	10.3	-1.9	0.2	-1.6	0.1	1.6	0.7	0.7	0.7	-0.4	1.2	-1.1	-1.7	-1.2	1.4	-0.2	-0.1	-0.3	-3.2
Average weekly red wine intake	0.9	1.4	4.3	1.5	1.4	1.9	1.0	0.3	0.7	0.7	0.8	-1.1	-0.6	0.9	1.2	0.9	0.3	-1.2	1.7	-2.1	-0.6
Handedness (chirality/laterality): Left-handed	2.0	2.5	6.7	-1.7	-2.1	-1.3	-0.9	-1.4	-2.1	-2.1	-2.1	1.0	1.6	0.2	-1.5	-1.2	0.6	-0.7	-1.7	-2.6	-1.0
Mood swings	1.2	2.2	7.4	-1.8	-2.3	-1.9	-1.9	-0.1	-1.2	-1.2	-1.3	1.5	0.0	-0.8	0.1	-2.3	0.4	-0.9	-1.6	-0.7	-2.7
Loneliness, isolation	0.6	0.8	4.6	-0.4	-0.8	-1.1	-1.5	0.6	0.1	0.1	0.0	0.3	0.0	-2.0	-0.6	-0.9	-0.3	-0.6	-0.4	-0.3	-2.1
Long-standing illness, disability or infirmity	1.1	1.6	6.0	-1.8	-1.8	-1.7	-1.7	1.1	-0.6	-0.6	-0.6	0.7	0.5	-0.9	-0.6	-2.5	0.5	0.3	-1.4	0.4	-2.1
Ever had bowel cancer screening	1.1	1.2	4.9	-0.8	-1.6	-1.0	-1.9	-0.8	-0.4	-0.4	-0.6	1.2	-1.1	0.4	-0.6	-1.5	-1.0	0.0	-2.2	1.1	0.4
Diabetes diagnosed by doctor	0.3	0.5	2.4	-0.3	-0.3	-0.6	-0.2	-0.1	0.9	0.9	0.8	0.5	-0.2	-1.5	-1.1	0.4	-0.1	0.1	-0.3	1.1	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.1	6.8	0.5	0.9	0.7	0.6	0.3	1.0	1.0	1.0	-1.3	0.3	-2.6	-1.3	-0.2	-0.7	-1.4	0.6	-1.3	-0.8
Friendships satisfaction	1.8	2.3	11.0	-1.0	-2.1	-1.0	-2.4	-0.7	-1.3	-1.3	-1.4	1.5	0.6	-3.3	-1.3	-1.1	-0.5	-0.3	-2.4	-0.5	-0.6
Qualifications: nursing, teaching	0.8	1.3	8.5	2.9	0.7	1.2	0.8	-0.3	-0.1	-0.1	-0.0	-2.0	-1.2	0.0	-0.0	1.6	-0.4	-0.5	1.0	-0.1	1.4
Commuting to job workplace: Walk	1.3	1.4	6.1	-1.1	-1.2	-0.2	-1.3	-1.8	-0.8	-0.8	-1.0	0.3	-0.4	-0.2	-1.6	-1.8	-2.5	-0.6	-1.8	-0.0	-0.0
Eye problems/disorders: Cataract	1.2	1.4	3.9	0.3	-0.4	1.3	0.0	-1.4	-1.2	-1.2	-1.2	-1.1	-1.4	1.2	-1.7	-1.4	-1.6	-2.0	0.5	-0.7	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	1.7	0.2	-0.7	1.3	-0.5	0.5	-0.2	-0.2	-0.3	-0.0	0.2	-0.2	0.9	0.7	1.3	0.4	-0.5	-0.7	-0.2
Medication for cholesterol	1.9	2.8	26.9	0.6	-0.7	0.6	-1.3	-0.9	0.2	0.2	0.1	2.1	-1.3	-0.5	0.4	0.2	-1.6	0.2	-2.2	2.4	5.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	3.2	-1.8	-1.1	0.1	-1.0	0.4	0.2	0.2	0.0	0.9	1.8	-1.4	-1.6	-1.5	-0.4	0.3	-0.7	0.4	-0.7
Back pain experienced in last month	1.7	2.5	8.6	-1.1	-2.1	-1.8	-2.9	-2.0	-0.5	-0.5	-0.7	1.8	-1.0	-0.7	1.1	-1.7	-2.6	-1.6	-1.6	1.9	-0.1
Mineral and other dietary supplements	1.2	1.6	6.1	1.2	1.9	0.5	2.5	0.8	0.6	0.6	0.8	-1.9	1.0	0.9	0.0	1.7	0.5	-0.1	1.0	-2.0	-1.5
Breast cancer (self-reported)	0.7	0.9	2.6	-0.7	0.7	-0.9	0.5	1.6	1.2	1.2	1.2	-0.8	1.0	0.3	0.9	0.5	0.0	1.4	1.1	0.8	-0.2
Asthma (self-reported)	0.6	1.2	6.4	0.3	0.0	0.5	0.3	1.4	1.7	1.7	1.6	-0.4	-0.2	-1.1	-0.5	-0.6	-0.0	1.1	0.1	2.5	1.5
Osteoporosis (self-reported)	2.1	2.6	7.2	1.6	1.3	2.7	1.2	1.5	2.3	2.3	2.3	-0.8	-0.1	1.6	2.5	0.8	1.0	0.1	1.5	1.6	0.7
Osteoarthritis (self-reported)	1.4	1.8	5.4	-1.7	-2.3	-1.7	-1.7	0.0	-0.7	-0.7	-0.8	1.8	1.4	-0.8	-0.2	-1.1	-0.8	1.4	-0.9	2.2	0.9
Medication: Aspirin	0.4	0.5	2.1	-1.4	-1.0	-1.0	-0.2	0.9	0.1	0.1	0.1	0.2	1.1	0.1	-0.7	-0.6	0.4	0.3	0.3	0.9	-0.4
Medication: Gliclazide	0.2	0.2	1.0	-0.0	-0.2	-0.3	0.0	0.7	0.5	0.5	0.5	0.4	0.9	0.7	-0.1	1.0	0.1	0.5	0.3	-0.3	0.1
Illnesses of father: None of the above (group 1)	0.8	0.9	6.5	-0.7	-0.2	0.2	0.7	-1.2	-1.2	-1.2	-1.1	-0.7	-0.2	1.3	-0.6	0.0	0.0	0.2	-0.4	-2.5	-1.1
Smoking status: Current	0.9	1.4	7.1	-1.0	0.6	-0.3	0.7	-0.2	-0.5	-0.5	-0.4	-1.4	-1.4	-2.7	-1.7	-0.6	0.3	0.3	0.6	-1.6	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	8.4	0.7	1.2	1.2	1.2	1.4	1.4	1.4	1.4	-0.2	-0.3	-0.0	-0.1	1.2	0.3	1.0	1.0	2.0	2.9
Whole body water mass	0.2	1.4	4.0	0.5	1.0	0.9	0.9	0.4	1.5	1.5	1.5	-2.0	-0.7	0.7	-1.6	-1.3	-1.2	-0.6	1.0	0.2	-1.9
Leg predicted mass (right)	0.4	1.9	5.2	0.6	1.5	1.0	1.6	1.0	1.8	1.8	1.8	-2.3	-0.9	0.1	-1.8	-1.1	-0.5	-0.4	1.1	0.0	-2.1
Arm fat mass (left)	0.4	1.7	12.2	-1.4	0.4	-0.8	0.4	1.2	0.9	0.9	0.9	-0.9	0.8	-0.7	-2.2	-1.8	0.7	-0.8	0.2	-0.4	-3.5
Number of self-reported non-cancer illnesses	0.7	1.3	3.5	-1.4	-1.5	-1.9	-1.2	0.9	-0.1	-0.1	-0.2	1.1	1.2	-0.7	-1.3	-1.4	1.0	0.6	-1.5	0.1	-1.6
Average weekly champagne plus white wine intake	0.4	0.5	1.8	1.0	0.4	0.9	0.3	-1.1	-0.5	-0.5	-0.4	-1.0	-0.4	-1.1	0.4	1.3	-0.1	-0.4	1.2	-0.3	0.1
Miserableness	0.7	1.3	5.0	-0.8	-1.6	-1.6	-1.9	0.5	0.1	0.1	-0.0	1.1	1.3	-1.4	-0.1	-1.2	1.1	-0.4	-0.6	0.5	-2.2
Guilty feelings	1.0	1.4	3.9	-0.5	-0.0	-1.8	-0.9	1.2	1.7	1.7	1.5	0.7	-0.1	1.6	0.5	-1.6	0.5	-0.1	-0.4	1.4	-2.0
Wears glasses or contact lenses	0.7	0.8	2.5	-0.5	-0.9	-1.2	-0.6	0.5	-0.6	-0.6	-0.6	1.6	1.4	-0.5	1.4	1.1	1.0	0.5	-0.7	-0.4	-0.3
Ever taken oral contraceptive pill	1.0	1.1	8.4	-0.9	0.4	-1.9	0.1	0.6	1.1	1.1	1.1	0.7	2.9	-0.9	-0.9	-0.7	-0.0	0.0	-0.1	-0.2	-0.2
Hearing aid user	0.5	0.6	1.9	-0.9	-0.2	0.6	-0.0	-1.3	-0.3	-0.3	-0.3	-0.9	-1.3	0.2	-0.3	-1.4	-1.3	-0.3	-0.3	0.0	-1.2
Mother’s age at death	0.8	1.0	6.0	0.6	-0.8	1.1	-1.0	-1.0	-0.7	-0.7	-0.8	0.9	-1.2	0.0	0.7	0.1	-1.1	0.3	-1.3	0.8	2.4
Financial situation satisfaction	1.0	1.2	5.7	-2.0	-1.4	-1.4	-0.4	0.9	-0.3	-0.3	-0.3	-0.5	0.0	-2.4	-1.3	-1.0	0.5	1.4	-0.1	-0.3	-1.3
Tinnitus: Yes, now most or all of the time	0.7	0.8	4.5	-0.9	-0.3	-2.1	-0.4	0.6	0.2	0.2	0.2	0.7	1.0	1.3	0.9	-1.0	0.5	1.5	0.0	-0.2	0.3
Commuting to job workplace: Public transport	0.8	1.0	4.8	-0.9	0.5	-1.3	0.4	0.8	0.7	0.7	0.7	0.1	0.9	-2.2	-1.1	0.7	1.6	1.5	0.4	0.2	-0.5
Eye problems/disorders: Glaucoma	1.4	1.7	5.6	2.1	1.5	1.2	1.7	1.4	1.6	1.6	1.6	0.3	0.9	-0.1	-0.4	1.1	2.4	0.1	1.1	0.6	0.9
Medication: Blood pressure	1.2	2.3	23.9	-0.7	0.0	-0.2	0.4	-0.4	-0.7	-0.7	-0.6	-1.5	0.8	0.7	-0.2	0.0	0.6	-1.3	1.7	-2.6	-4.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.8	-0.7	-0.2	-1.7	0.4	1.3	1.0	1.0	0.9	-0.0	0.3	-1.4	0.3	0.0	1.2	1.4	-0.6	1.9	0.7
Supplements: Fish oil (including cod liver oil)	2.7	3.5	10.8	-1.9	-3.0	-0.7	-3.3	-2.0	-1.7	-1.7	-1.8	2.3	-1.5	-0.8	0.3	-3.0	-1.4	-1.3	-2.2	0.9	0.6
High cholesterol (Self-reported)	1.2	2.2	5.4	-2.2	-2.2	-1.6	-1.5	-1.2	-1.1	-1.1	-1.2	0.8	2.1	-0.0	-1.8	-2.3	-1.0	-0.2	-0.9	-0.3	-1.6
Medication: Bendroflumethiazide	0.5	0.7	5.5	-0.3	1.0	0.2	0.3	1.2	0.7	0.7	0.8	-0.4	0.5	0.2	0.6	0.5	0.8	0.3	1.2	0.2	-2.3
Medication: Paracetamol	0.6	0.9	4.2	-0.5	-1.1	0.2	-1.4	0.7	0.6	0.6	0.4	2.1	0.3	0.3	2.0	-1.0	0.5	-0.2	-0.7	1.0	-0.7
Medication: Lisinopril	1.1	1.4	3.7	-1.6	-1.1	-1.7	-1.6	0.7	0.5	0.5	0.3	1.9	1.4	-0.6	-1.8	-1.1	-0.7	0.3	-1.2	1.0	-0.8
Medication: Atorvastatin	0.6	0.7	3.8	-1.2	-0.6	-2.0	-0.8	0.4	-0.2	-0.2	-0.2	0.5	1.6	-1.5	0.3	-0.1	0.6	1.0	-0.1	-0.1	-0.7
Illnesses of father: High blood pressure	1.7	2.1	13.5	-0.0	-0.1	-0.4	-1.3	0.3	1.8	1.8	1.6	0.8	-1.3	-0.6	-0.5	-1.3	-2.3	-0.0	-0.4	3.7	1.9
Alcohol drinker status: Never	0.6	0.7	4.8	1.3	1.0	0.8	1.2	0.0	-0.2	-0.2	-0.0	-2.2	-1.0	0.5	-0.4	0.7	0.7	-0.1	1.0	-0.4	-0.4
Ever smoked	0.8	1.4	3.3	-0.0	1.8	-0.2	1.5	1.2	1.5	1.5	1.6	-1.5	-0.8	-1.7	-0.1	-0.2	-0.2	0.2	1.8	1.1	-1.0
Basal metabolic rate	0.2	1.3	5.2	0.3	1.0	0.8	0.9	0.5	1.4	1.4	1.4	-1.8	-0.3	0.5	-1.7	-1.3	-0.8	-0.7	0.8	-0.0	-2.3
Leg fat percentage (left)	0.8	2.8	20.4	-2.7	-1.2	-1.6	-1.6	0.0	-0.9	-0.9	-1.0	0.3	1.2	-0.3	-1.8	-2.2	0.3	-1.5	-0.5	-1.3	-4.5
Arm fat-free mass (left)	0.3	1.5	5.6	0.4	0.8	1.2	0.8	0.3	1.3	1.3	1.2	-2.0	-0.4	0.8	-1.8	-1.6	-1.0	-1.0	1.0	-0.1	-2.4
Number of operations (self-reported)	3.1	4.5	13.5	-1.7	-3.7	-1.9	-3.3	-2.0	-2.1	-2.1	-2.3	2.4	0.2	-2.8	-1.8	-2.4	-1.9	-0.6	-2.3	0.7	0.0
Average weekly beer plus cider intake	0.9	1.3	4.8	-0.8	1.4	-0.5	1.8	0.6	0.4	0.4	0.6	-2.2	-0.6	-1.5	-1.3	0.2	0.2	1.5	1.6	-0.4	-1.6
Irritability	1.1	1.9	5.5	-0.7	-1.6	-1.9	-2.3	-0.8	-1.3	-1.3	-1.4	1.2	-0.1	-0.6	-0.6	-0.9	-1.0	-1.2	-1.0	-1.9	-2.4
Risk taking	5.0	7.3	19.1	2.0	4.4	2.0	3.7	3.0	4.0	4.0	4.2	-3.5	-0.2	-1.3	0.5	1.5	0.8	1.2	3.4	0.7	-1.2
Ever had prostate specific antigen (PSA) test	1.2	1.4	4.3	-0.4	-1.4	-1.4	-1.5	-1.2	-0.6	-0.6	-0.8	1.1	-1.4	0.8	0.5	0.3	-2.1	-0.9	-1.7	1.3	1.5
Fractured/broken bones in last 5 years	1.0	1.2	2.7	0.5	1.5	1.0	0.8	0.7	1.6	1.6	1.6	-1.4	0.1	-1.5	-1.0	-0.2	-1.1	0.9	1.0	0.7	1.0
Age started oral contraceptive pill	1.2	1.5	5.1	0.5	0.2	0.3	-1.1	0.8	1.4	1.4	1.2	2.0	1.0	0.9	2.2	0.7	0.0	-0.8	-1.7	1.7	1.4
Diastolic blood pressure, automated reading	1.0	3.0	5.6	-1.6	-2.2	-1.5	-1.8	-2.1	-2.3	-2.3	-2.4	0.5	-2.2	1.2	-0.4	-2.4	-2.1	-1.0	-1.7	-0.1	-0.8
Ever depressed for a whole week	1.2	1.5	5.8	-0.1	-0.7	-1.7	-0.8	0.8	0.8	0.8	0.7	1.0	1.2	-0.2	1.8	0.0	-0.4	1.4	-1.5	2.0	2.4
Unable to work because of sickness or disability	0.6	0.8	1.8	1.0	1.1	1.2	0.8	1.1	1.2	1.2	1.3	-0.8	0.2	-0.1	0.4	1.2	1.0	-0.6	0.2	-0.4	0.1
Commuting to job workplace: Cycle	1.2	1.4	6.8	1.7	1.6	1.3	1.6	-0.8	-0.3	-0.3	-0.1	-1.4	-2.6	1.1	0.7	1.3	-0.0	0.2	1.4	-1.0	0.5
Myopia	1.3	1.9	4.8	1.0	1.4	-1.1	1.3	1.8	1.6	1.6	1.7	-0.1	1.5	-0.2	2.2	2.0	1.8	1.7	0.5	-0.1	-0.3
Vascular/heart problems diagnosed by doctor	0.6	1.6	9.7	1.8	1.2	1.8	1.3	-0.2	0.4	0.4	0.6	0.3	-0.5	0.9	1.7	2.1	0.5	0.1	0.2	0.6	3.1
Cholesterol lowering medication	0.9	1.4	11.4	-0.7	0.6	0.3	0.9	-0.4	0.3	0.3	0.4	-1.7	0.3	-0.4	-1.4	-1.2	-0.7	-0.2	1.7	-0.9	-3.4
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	6.3	-0.4	0.9	-0.6	0.4	2.3	2.0	2.0	2.0	0.1	2.5	0.8	2.0	0.3	0.9	1.5	0.9	1.7	0.6
Pain experienced in last month	0.5	0.9	2.7	0.5	0.3	0.5	1.0	-1.5	-1.3	-1.3	-1.2	-0.6	-0.5	0.8	-1.6	0.4	-1.1	-0.3	-0.3	-1.4	0.7
Supplements: Calcium	1.0	1.1	4.3	1.1	0.7	1.1	0.2	1.3	0.9	0.9	0.9	1.2	2.1	-0.5	0.4	1.6	1.5	-0.3	0.5	0.2	0.9
Basal cell carcinoma (self-reported)	0.4	0.5	2.8	0.7	0.6	1.7	0.5	-0.6	0.3	0.3	0.3	-1.1	-0.9	0.3	0.2	-0.7	-0.3	-0.7	1.2	0.1	-0.4
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.9	-1.4	-0.1	-0.9	-0.1	-0.1	0.2	0.2	0.2	-1.1	-0.3	-1.3	-1.4	-1.4	-0.3	0.1	1.0	0.4	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	3.3	-1.0	-0.9	-0.2	-1.1	1.1	1.3	1.3	1.1	-0.1	-0.5	-0.4	-0.1	-1.2	-0.0	1.3	-0.3	1.8	-0.7
Heart disease (siblings)	0.4	0.5	1.9	0.4	0.3	0.3	0.4	0.9	0.8	0.8	0.8	0.1	0.6	-0.9	-0.2	-0.8	1.4	-0.7	0.7	-0.1	-1.0
Alcohol drinker status: Previous	0.6	0.7	3.1	0.3	0.1	-0.2	0.9	-0.6	0.6	0.6	0.6	-0.5	-1.8	-0.5	-0.7	-1.3	-0.1	-0.8	-0.2	0.9	1.5
Pack years of smoking	0.4	0.6	3.1	0.1	-0.7	-0.3	-0.6	-0.4	0.1	0.1	0.1	-0.5	0.4	-0.8	-1.4	-1.1	-1.3	-0.1	-0.4	-0.9	-1.8
Impedance of whole body	0.4	2.1	9.6	-0.0	0.2	-1.6	0.1	0.6	-1.1	-1.1	-1.0	1.8	2.4	0.0	2.5	2.0	3.1	0.5	-1.0	-1.0	0.2
Leg fat mass (left)	0.6	2.5	19.3	-2.2	-0.8	-1.2	-1.0	0.0	-0.2	-0.2	-0.3	-0.3	0.9	-0.7	-2.3	-2.5	-0.2	-1.8	-0.1	-0.9	-4.4
Arm predicted mass (left)	0.2	1.2	4.4	0.2	0.7	0.9	0.5	0.3	1.4	1.4	1.3	-1.7	-0.2	0.8	-1.4	-1.6	-1.0	-0.7	0.9	0.3	-2.1