Best TWAS P=2.62e-09 · Best GWAS P=1.08e-11 conditioned to 3.13e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | RFTN2 | 0.06 | 0.08 | lasso | 8 | 0.06 | 2.7e-05 | -5.7 | -5.6 | 2.1e-08 | -0.72 | 0.76 | 0.22 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | MARS2 | 0.04 | 0.05 | enet | 8 | 0.03 | 1.2e-03 | -5.3 | 5.4 | 6.6e-08 | 0.72 | 0.54 | 0.44 | FALSE |
| 3 | GTEx | Spleen | RFTN2 | 0.11 | 0.03 | enet | 26 | 0.05 | 2.4e-02 | -5.4 | -5.6 | 1.7e-08 | -0.71 | 0.12 | 0.16 | FALSE |
| 4 | GTEx | Spleen | MARS2 | 0.12 | 0.04 | lasso | 5 | 0.00 | 3.4e-01 | -5.4 | 5.3 | 1.0e-07 | 0.68 | 0.08 | 0.23 | FALSE |
| 5 | GTEx | Thyroid | RFTN2 | 0.04 | 0.01 | enet | 11 | 0.01 | 9.5e-02 | -5.3 | -5.3 | 1.5e-07 | -0.67 | 0.18 | 0.45 | FALSE |
| 6 | GTEx | Whole Blood | PLCL1 | 0.08 | 0.08 | enet | 15 | 0.05 | 4.1e-05 | -6.1 | -5.8 | 5.0e-09 | -0.76 | 0.13 | 0.87 | FALSE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PLCL1 | 0.04 | 0.00 | blup | 130 | 0.02 | 4.0e-03 | 3.4 | -6.0 | 2.6e-09 | -0.56 | 0.06 | 0.27 | TRUE |