Best TWAS P=7.25e-24 · Best GWAS P=3.87e-25 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | AC016757.3 | 0.37 | 0.14 | enet | 19 | 0.25 | 5.4e-13 | -1.9 | -6.0 | 2.0e-09 | 0.69 | 0.41 | 0.59 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | AC016757.3 | 0.13 | -0.01 | enet | 22 | -0.01 | 5.2e-01 | -2.4 | -5.2 | 1.8e-07 | 0.41 | 0.04 | 0.36 | FALSE |
| 3 | GTEx | Esophagus Muscularis | AC016757.3 | 0.25 | 0.07 | enet | 11 | 0.14 | 6.1e-09 | -2.6 | -5.4 | 6.4e-08 | 0.63 | 0.21 | 0.79 | FALSE |
| 4 | GTEx | Testis | TRAF3IP1 | 0.30 | 0.02 | lasso | 4 | 0.05 | 2.1e-03 | -9.0 | 8.8 | 8.5e-19 | -0.79 | 0.03 | 0.78 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | KLHL30 | 0.10 | 0.03 | blup | 50 | 0.04 | 2.4e-09 | 2.4 | -5.7 | 1.6e-08 | 0.16 | 0.92 | 0.00 | TRUE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TRAF3IP1 | 0.06 | 0.03 | lasso | 3 | 0.03 | 2.7e-06 | -10.4 | -10.1 | 7.3e-24 | 0.99 | 0.00 | 1.00 | TRUE |