Hub : Genes

AC016757.3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.374 0.0500 0.0e+00 0.297 NA 0.313 NA 0.313 1.3e-24 NA 4.2e-26 NA 4.3e-26
2 GTEx Adipose Visceral Omentum 0.236 0.0590 4.5e-05 0.072 NA 0.124 NA 0.120 1.4e-04 NA 5.4e-07 NA 8.5e-07
3 GTEx Adrenal Gland 0.327 0.0854 1.1e-04 0.209 NA 0.274 NA 0.277 4.9e-08 NA 2.3e-10 NA 1.8e-10
4 GTEx Artery Aorta 0.148 0.0490 9.5e-04 0.064 NA 0.069 NA 0.052 2.1e-04 NA 1.1e-04 NA 8.0e-04
5 GTEx Artery Coronary 0.430 0.0740 2.1e-07 0.200 NA 0.183 NA 0.245 2.5e-07 NA 9.2e-07 NA 8.7e-09
6 GTEx Artery Tibial 0.383 0.0495 0.0e+00 0.271 NA 0.358 NA 0.306 2.5e-21 NA 3.3e-29 NA 2.3e-24
7 GTEx Breast Mammary Tissue 0.367 0.0640 4.1e-10 0.138 NA 0.247 NA 0.230 1.4e-07 NA 5.4e-13 NA 4.4e-12
8 GTEx Breast Mammary Tissue (Female) 0.128 0.1178 1.9e-01 -0.008 NA -0.006 NA -0.009 6.7e-01 NA 5.2e-01 NA 8.3e-01
9 GTEx Cells EBV-transformed lymphocytes 0.561 0.0890 1.6e-07 0.233 NA 0.086 NA 0.171 3.7e-08 NA 9.5e-04 NA 3.3e-06
10 GTEx Cells Transformed fibroblasts 0.322 0.0520 8.4e-13 0.240 NA 0.239 NA 0.268 6.0e-18 NA 7.2e-18 NA 3.2e-20
11 GTEx Esophagus Muscularis 0.246 0.0560 1.1e-06 0.073 NA 0.142 NA 0.136 3.2e-05 NA 6.1e-09 NA 1.3e-08
12 GTEx Heart Atrial Appendage 0.333 0.0710 2.2e-06 0.142 NA 0.187 NA 0.183 6.5e-07 NA 8.5e-09 NA 1.2e-08
13 GTEx Heart Left Ventricle 0.286 0.0649 1.7e-06 0.129 NA 0.176 NA 0.199 2.4e-07 NA 1.1e-09 NA 7.7e-11
14 GTEx Lung 0.349 0.0499 9.6e-15 0.106 NA 0.258 NA 0.245 1.9e-08 NA 9.3e-20 NA 9.9e-19
15 GTEx Ovary 0.434 0.0890 1.7e-05 0.256 NA 0.210 NA 0.275 5.5e-07 NA 7.0e-06 NA 1.8e-07
16 GTEx Skin Sun Exposed Lower leg 0.204 0.0450 1.5e-08 0.106 NA 0.123 NA 0.109 4.2e-09 NA 2.2e-10 NA 2.4e-09
17 GTEx Spleen 0.406 0.0970 8.8e-05 0.272 NA 0.342 NA 0.330 1.1e-07 NA 1.3e-09 NA 3.0e-09
18 GTEx Testis 0.309 0.0740 2.0e-05 0.183 NA 0.222 NA 0.202 1.6e-08 NA 3.3e-10 NA 2.3e-09
19 GTEx Thyroid 0.132 0.0420 3.9e-04 0.080 NA 0.070 NA 0.080 1.1e-06 NA 4.6e-06 NA 9.7e-07
20 GTEx Uterus 0.425 0.1510 5.3e-03 0.029 NA 0.014 NA -0.006 8.6e-02 NA 1.6e-01 NA 4.5e-01
21 GTEx Vagina 0.470 0.0970 2.7e-05 0.163 NA 0.215 NA 0.248 1.5e-04 NA 1.1e-05 NA 2.1e-06
22 GTEx Whole Blood 0.186 0.0490 6.8e-06 0.021 NA 0.061 NA 0.045 4.2e-03 NA 2.7e-06 NA 5.0e-05
23 METSIM Adipose 0.276 0.0430 0.0e+00 0.095 0.191 0.188 0.207 0.172 4.6e-14 7.7e-28 2.4e-27 2.6e-30 4.8e-25
24 ROSMAP Brain Pre-frontal Cortex 0.181 0.0448 8.1e-08 0.076 0.099 0.091 0.108 0.103 5.5e-10 1.0e-12 1.0e-11 9.2e-14 3.4e-13

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bipolar Disorder (2018) 1.0 1.5 7.2 -1.4 -1.8 -0.3 0.5 -1.6 -1.6 -0.9 -0.8 0.5 -1.7 -0.6 -1.3 -1.0 -1.2 -0.1 -0.4 -1.7 2.7 -0.9 -0.7 0.4 -1.3 -1.4 0.6
Bipolar Disorder or Schizophrenia 1.7 4.3 8.2 -2.3 -2.5 -1.9 -1.0 -2.1 -2.2 -2.5 -2.8 -1.4 -2.3 -2.4 -2.0 -2.4 -2.4 -1.8 -1.3 -2.8 2.9 -1.8 -0.3 0.1 -2.0 -2.2 -0.8
Depressed Affect (Nagel 2018) 1.5 3.1 6.5 -2.5 -2.5 -1.9 -1.0 -2.5 -2.3 -1.5 -1.4 -1.3 -2.5 -1.5 -1.9 -1.9 -1.6 -1.8 -0.8 -1.9 2.6 0.4 -1.0 -1.6 -0.8 -1.9 -0.4
Depression (Nagel 2018) 1.7 2.5 5.1 -1.9 -2.2 -1.8 -1.2 -2.3 -1.9 -1.7 -2.0 -1.3 -2.1 -1.7 -1.7 -1.7 -1.6 -1.6 -0.8 -1.2 1.8 0.5 -1.1 -0.5 -0.8 -2.0 -0.7
Intelligence (Savage-Jansen 2018) 0.7 2.2 5.2 1.5 1.6 1.0 1.7 1.2 1.5 1.6 0.1 1.3 1.1 1.3 0.8 1.5 1.5 0.7 2.2 1.6 -1.5 1.7 1.3 2.1 2.3 1.4 0.9
Neuroticism (Nagel 2018) 1.2 2.8 6.0 -2.3 -2.3 -2.0 -0.9 -2.3 -2.2 -1.3 -1.2 -1.5 -2.2 -1.4 -1.4 -1.9 -1.6 -1.9 -0.9 -2.0 2.4 -0.0 -0.6 -1.0 -0.9 -1.9 -0.9
Schizophrenia (2018) 1.7 3.5 9.1 -1.7 -1.7 -2.2 -1.7 -1.4 -1.5 -2.5 -3.0 -2.3 -1.6 -2.6 -1.5 -2.2 -2.1 -2.2 -1.3 -2.2 1.6 -1.5 0.2 -0.3 -1.7 -1.6 -1.5
Schizophrenia vs Biploar Disorder 1.0 1.3 3.1 -0.3 -0.3 -1.4 -0.5 -0.2 -0.2 -1.4 -1.2 -1.5 -0.3 -1.3 -0.5 -1.2 -1.3 -1.6 -1.2 -0.0 -1.2 -1.8 -0.9 -1.5 -1.5 -0.7 -1.6
Worry (Nagel 2018) 1.5 3.1 5.3 -2.0 -2.1 -2.0 -1.3 -2.1 -2.1 -1.5 -1.5 -1.6 -1.9 -1.8 -1.3 -2.2 -2.0 -2.0 -1.8 -2.2 2.3 -1.3 0.1 -0.9 -1.4 -1.8 -1.6
Alzheimer’s Disease (in mother) 1.3 1.6 3.7 1.2 1.2 1.1 1.6 0.9 1.5 1.9 1.1 1.2 1.1 1.2 1.1 1.3 1.1 1.1 1.3 1.0 -1.3 1.0 -1.0 1.5 1.2 0.4 1.7
Alzheimer’s Disease (in father) 0.3 0.4 2.8 0.9 0.6 -0.1 0.2 0.3 0.9 0.1 0.6 0.1 0.3 0.1 0.6 0.4 0.2 -0.2 0.1 0.7 -0.8 -0.0 0.1 1.3 0.3 -0.0 1.7
Alzheimer’s Disease (including proxy) 0.7 1.0 4.7 1.1 1.1 0.6 1.1 0.9 1.4 1.2 0.8 0.6 0.7 0.9 1.3 1.0 0.5 0.5 0.4 0.8 -0.9 0.1 -0.9 1.7 0.6 -0.4 2.2
Crohns Disease (2017) 0.1 0.3 1.9 0.1 0.6 -0.1 0.1 0.4 0.2 0.1 0.9 0.2 0.2 -0.0 -0.4 0.0 0.0 -0.3 -0.2 -0.3 -0.3 -0.9 -1.2 -1.4 0.3 -0.6 -0.4
Irritable Bowel Disease (IBD) 0.1 0.4 1.4 0.6 0.9 0.1 0.2 0.7 0.9 0.5 1.2 0.5 0.5 0.3 -0.2 0.2 0.2 -0.1 0.7 0.2 -0.6 -0.4 0.1 -1.0 0.8 0.2 -0.9
Ulcerative Colitis (UC) 0.4 0.7 2.5 1.1 1.1 0.4 0.2 0.9 1.4 0.8 1.0 0.6 0.7 0.6 0.1 0.5 0.6 0.3 1.6 0.6 -0.5 0.4 1.3 -0.2 1.4 1.1 -0.8
Major Depression (MDD) 0.4 0.5 3.2 -0.6 -0.6 -0.0 0.7 -0.6 -0.2 -0.6 -1.8 -0.1 -0.6 -0.8 -0.6 -0.1 -0.0 -0.0 -0.1 -0.6 0.4 0.6 0.1 1.6 0.1 -1.1 1.3
Reaction Time 0.2 0.3 2.0 -0.3 -0.4 -0.1 0.3 -0.3 -0.5 0.4 0.6 -0.2 -0.2 0.3 -0.3 -0.4 -0.2 -0.0 -0.2 -0.9 1.4 -0.9 -0.2 -0.9 -0.4 -1.0 -0.8
Verbal and Numeric Reasoning (VNR) 0.7 1.8 3.6 1.6 1.3 1.0 1.8 1.4 1.6 1.7 0.5 1.5 1.2 1.5 1.2 1.3 1.1 0.9 1.9 1.6 -1.1 1.1 1.7 0.9 1.4 0.8 0.4
Breast Cancer 0.1 0.3 1.1 0.4 0.4 0.7 -0.3 0.8 0.6 0.4 0.8 0.7 0.6 0.8 0.7 0.3 0.3 0.7 0.0 0.2 -0.3 -0.4 -0.5 -0.2 -0.2 1.0 -0.1
Ovarian Cancer 1.1 1.5 5.3 1.1 1.3 1.2 0.1 0.8 1.2 1.7 0.2 0.7 0.9 0.9 0.9 1.5 2.0 1.2 1.1 0.8 -1.3 2.3 -1.0 0.9 2.1 0.7 1.0
Prostate Cancer 0.6 0.9 3.1 -1.1 -0.8 -1.1 -1.0 -1.2 -1.0 -1.0 -0.4 -0.8 -1.2 -1.3 -1.8 -1.0 -0.8 -1.1 -0.3 -0.9 0.3 0.3 -0.3 -0.4 -0.3 -0.8 -1.1
Age at First Birth 0.2 0.2 1.3 -0.3 -0.0 -0.5 -0.1 -0.1 -0.0 -0.6 -1.2 -0.9 -0.2 -0.5 -0.9 -0.2 -0.1 -0.6 -0.3 -0.0 -0.6 0.0 -0.4 0.6 -0.3 -0.2 -0.2
Bipolar Disorder (2011) 1.4 1.3 2.3 -1.2 -1.4 -1.5 -1.4 -1.5 -1.5 -1.1 -0.3 -1.2 -1.5 -1.3 -1.3 -1.5 -1.0 -1.4 -0.4 -1.3 1.5 -0.3 0.1 -0.9 -0.3 -1.1 -0.3
Body Mass Index (BMI) (2010) 1.1 1.4 5.3 1.1 1.2 1.1 1.6 1.2 1.5 1.1 2.3 0.9 1.3 1.6 0.9 1.3 1.2 1.1 0.9 1.3 -1.4 0.4 -0.5 1.1 1.1 0.9 -0.0
Coronary Artery Disease (CAD) 0.2 0.2 1.3 0.4 0.3 0.2 -0.0 0.4 1.1 0.3 -0.6 0.6 0.4 0.3 -0.1 0.6 0.5 0.2 0.6 0.7 -0.3 0.6 -0.0 0.1 0.8 -0.1 -0.4
Crohns Disease (2012) 0.2 0.3 1.7 0.0 0.2 0.3 0.0 0.2 -0.2 0.4 1.1 1.0 0.2 0.6 -0.3 0.1 0.1 0.2 -0.4 -0.3 0.4 -0.7 -0.3 -1.3 0.3 -0.2 -1.0
Mean Putamen Volume 0.2 0.2 1.5 -0.2 -0.1 0.3 1.2 0.3 -0.1 0.3 -0.4 0.3 0.1 0.2 0.5 0.2 0.2 0.4 0.2 -0.0 0.4 0.3 0.2 1.2 -0.4 0.2 0.9
Fasting Glucose 1.1 1.3 3.7 -0.9 -1.3 -1.8 -0.4 0.1 -0.9 -1.1 -0.7 -0.3 -1.0 -0.8 -0.6 -1.9 -1.3 -1.7 -0.4 -1.1 1.3 -0.5 -1.5 -0.4 -1.5 -1.5 -1.3
HbA1C 0.4 0.4 2.5 0.0 -0.2 0.2 0.1 0.0 0.3 0.3 1.2 -0.3 0.3 0.7 0.4 0.0 -0.5 0.1 -0.6 0.5 -0.4 -1.0 0.5 -1.2 -1.1 -0.5 -1.6
HDL Cholesterol 0.3 0.5 1.8 -1.0 -0.8 -0.5 0.8 -0.7 -1.2 -0.7 -1.2 0.0 -0.6 -0.4 -0.6 -0.7 -0.5 -0.4 -0.3 -0.7 1.3 0.1 0.4 0.7 -0.9 -0.3 0.4
LDL Cholesterol 1.0 1.6 3.5 -1.3 -1.1 -1.1 -0.7 -1.2 -1.0 -1.6 -1.7 -1.0 -1.2 -1.2 -0.8 -1.3 -1.5 -1.1 -1.9 -1.6 1.2 -1.8 -0.4 -1.0 -1.3 -1.3 -0.6
Lupus 0.2 0.2 1.6 0.1 0.0 -0.0 -1.3 0.1 0.3 -0.1 -0.0 -0.9 0.2 -0.6 0.1 0.0 -0.3 0.0 -0.1 -0.4 -0.2 -0.6 -0.7 -0.7 -0.6 -0.9 0.0
Neuroticism (2016) 1.4 2.0 4.7 -1.6 -1.7 -1.6 -1.3 -2.1 -1.5 -0.8 -1.4 -1.6 -1.8 -1.5 -1.4 -1.6 -1.1 -1.6 0.3 -1.6 2.2 0.8 -1.1 -0.4 -0.4 -1.3 -1.3
Primary Biliary Cirrhosis 1.0 1.4 5.1 -0.9 -1.0 -0.9 -0.9 -0.7 -0.8 -1.1 0.1 -0.8 -0.8 -1.0 -0.5 -1.1 -1.6 -0.9 -1.2 -1.4 1.4 -2.2 -1.3 -0.1 -1.3 -1.9 -1.5
Rheumatoid Arthritis 0.4 0.6 1.9 -0.7 -0.3 -1.0 -0.8 -0.6 -0.7 -0.5 0.2 -1.1 -0.8 -0.9 -0.4 -0.7 -0.7 -1.0 -0.7 -1.0 0.4 -0.5 1.3 -1.4 -0.4 -0.8 -0.1
Schizophrenia (2014) 0.6 1.4 6.7 -0.9 -1.0 -1.1 -0.5 -0.5 -0.7 -1.8 -2.6 -1.2 -0.6 -1.6 -0.5 -1.2 -1.5 -1.1 -1.2 -1.1 0.5 -1.9 0.0 0.5 -1.4 -0.9 -0.5
Triglycerides 0.2 0.3 2.2 0.3 -0.1 0.1 -0.4 0.3 0.8 0.0 0.4 -0.2 0.2 -0.3 0.9 -0.1 -0.1 0.0 0.7 -0.0 -0.2 -0.6 -1.5 0.4 -0.4 -0.5 1.0
Type 2 Diabetes (T2D) (2012) 0.8 0.9 4.1 -0.7 -1.0 -0.6 -0.6 -0.4 -0.8 -0.8 -0.4 -1.1 -0.5 -0.6 -0.8 -0.9 -1.3 -0.6 -1.0 -0.9 0.6 -1.9 0.4 -0.4 -2.0 -1.8 -0.2
Ulcerative Colitis 0.6 0.9 2.9 1.2 0.9 0.8 0.2 0.8 1.1 1.2 1.1 1.1 0.8 0.7 0.1 0.7 0.7 0.8 1.7 0.6 -0.3 0.7 0.7 0.2 1.6 1.3 -0.6
Blood Eosinophil Count 0.3 2.0 4.2 1.6 1.6 1.4 0.3 1.4 1.9 1.5 2.0 1.6 1.5 1.3 0.7 1.6 1.6 1.6 0.9 1.5 -1.7 1.1 -0.1 1.3 1.2 1.0 1.2
Blood Platelet Count 0.1 0.9 7.7 -0.9 -0.7 0.3 0.8 -0.3 -1.0 -0.0 0.0 -0.2 -0.3 0.1 -0.4 -0.3 -0.4 0.4 -0.8 -1.6 1.4 -1.4 0.2 -0.7 -1.4 -0.1 -2.8
Blood Red Count 0.0 0.2 1.7 -0.2 -0.1 0.1 0.3 0.1 -0.4 0.1 -0.0 0.0 0.1 0.4 1.1 -0.0 0.2 0.0 -0.0 -0.1 0.2 -0.3 1.3 -0.5 -0.2 -0.2 -0.5
Blood White Count 0.0 0.3 1.5 -0.2 -0.5 -0.4 0.6 -0.4 -0.1 -0.2 0.2 0.2 -0.5 0.4 -0.7 -0.4 -0.7 -0.2 0.4 -0.6 0.7 -0.5 0.3 1.2 -1.1 -1.2 0.0
Heel T-Score 1.0 7.8 14.2 3.8 3.0 2.4 2.9 2.6 3.4 3.7 2.9 3.4 2.6 3.2 3.5 2.7 2.2 2.5 2.8 3.6 -2.8 1.6 1.0 1.6 2.1 2.1 2.5
BMI 1.2 6.8 14.3 2.8 1.9 2.4 3.8 2.3 2.5 3.6 3.7 2.8 2.2 3.5 3.0 2.5 2.1 2.4 3.0 2.6 -2.1 0.9 2.2 2.3 1.3 1.2 2.9
Height 1.0 20.0 49.3 -3.9 -3.1 -4.2 -7.0 -2.9 -3.7 -5.9 -1.4 -6.2 -3.1 -6.2 -4.2 -4.2 -3.7 -4.4 -4.9 -5.4 2.8 -4.2 -5.7 -3.8 -4.6 -1.6 -5.0
Waist Hip Ratio (WHR) 0.5 2.1 11.0 -1.6 -1.7 -1.4 -0.3 -1.6 -1.5 -1.6 -1.6 -1.1 -1.4 -1.1 -0.9 -1.4 -1.4 -1.3 -0.2 -0.7 1.0 0.4 -3.3 0.7 -1.6 -2.4 -0.2
Systolic Blood Pressure 0.4 2.1 9.4 -1.4 -0.8 -1.1 -1.2 -1.2 -1.6 -1.2 -0.7 -1.5 -1.2 -1.3 -1.4 -1.2 -1.2 -1.1 -1.5 -2.3 1.5 -0.9 1.4 -2.1 -1.0 -0.9 -3.1
Smoking Status 0.1 0.4 0.9 -0.6 -0.6 -0.6 -0.4 -0.8 -0.5 -0.7 -0.9 0.1 -0.8 -0.2 -0.9 -0.5 -0.5 -0.6 0.1 -0.5 0.5 0.6 -0.9 0.9 -0.1 0.2 -0.3
Allergy or Eczema 1.3 3.5 13.3 1.9 2.0 1.5 1.9 1.5 1.7 2.2 0.9 1.7 1.2 1.7 1.1 2.0 1.8 1.4 2.3 1.9 -1.4 2.0 3.6 0.8 2.7 2.0 1.6
Cardiovascular Disease 0.9 3.1 6.6 1.4 1.3 1.8 2.4 1.2 1.5 2.2 0.8 1.9 1.4 2.1 2.1 1.8 2.1 1.9 1.9 1.4 -1.2 2.1 0.5 2.3 1.6 0.8 2.6
Hypothyroidism (self reported) 0.3 0.6 1.8 0.7 0.5 1.2 0.6 0.8 0.6 1.2 0.1 1.3 0.6 1.0 0.6 1.0 0.3 1.2 0.3 0.8 -0.1 0.1 0.2 -1.0 0.7 -0.2 1.3
Respiratory disease 0.2 0.4 2.6 0.7 0.7 0.3 1.6 0.8 1.0 0.7 0.1 -0.0 0.8 0.7 0.5 0.4 0.2 0.2 0.5 0.2 -0.3 -0.4 0.5 -0.5 0.3 0.2 -0.4
Type 2 Diabetes (T2D) (2018) 0.9 1.8 11.0 0.9 0.9 0.3 1.6 0.2 1.0 1.6 0.6 0.9 0.1 1.0 0.4 1.1 1.0 0.4 2.2 1.5 -0.2 3.3 -0.2 2.2 1.7 0.7 1.8
Lung FEV1/FVC ratio 1.5 7.6 25.1 2.8 1.9 2.6 3.7 1.8 2.1 5.0 1.7 4.5 1.8 4.1 2.8 2.4 1.9 2.7 2.9 2.1 -0.4 2.0 3.0 1.2 2.5 2.2 3.5
Lung FVC 1.6 8.4 17.0 3.1 2.1 2.3 3.5 2.0 3.3 4.1 0.9 4.0 2.1 4.1 2.1 2.4 2.3 2.4 3.5 3.3 -1.5 2.7 2.9 1.9 3.7 2.8 3.5
Neuroticism 1.2 2.8 6.0 -2.5 -2.3 -1.7 -1.3 -2.2 -2.3 -1.4 -1.5 -1.5 -2.2 -1.6 -1.9 -1.8 -1.4 -1.7 -1.0 -2.1 2.4 -0.1 0.1 -0.7 -0.9 -1.3 -1.0
Chronotype (morning person) 5.4 12.4 36.0 -4.5 -3.5 -2.6 -3.5 -2.7 -4.3 -6.0 -5.2 -4.3 -2.7 -5.4 -2.8 -3.1 -2.6 -2.5 -4.5 -3.5 2.2 -2.0 -2.7 -0.4 -4.0 -1.5 -2.2
Hair Pigment 0.0 1.4 4.0 1.7 1.6 1.4 0.5 1.6 2.0 0.8 0.2 0.5 1.7 1.1 1.5 1.3 1.4 1.3 -0.8 1.2 -1.3 -0.4 -0.0 0.2 0.8 1.2 -0.8
Tanning 0.1 1.5 5.4 -1.3 -0.9 -1.0 -1.8 -1.4 -1.4 -1.7 -1.8 -1.2 -1.5 -2.3 -1.2 -0.7 -0.3 -0.9 -0.9 -1.3 1.0 1.2 -1.1 -0.7 0.3 -1.1 0.9
Hand grip strength (left) 0.3 0.8 2.4 0.8 0.9 1.0 0.4 1.2 1.1 0.4 1.2 0.5 1.1 0.7 1.0 0.9 1.0 1.1 -0.3 0.7 -1.3 0.0 -0.4 0.2 0.3 1.6 -0.3
Number of treatments/medications taken 0.3 0.6 3.6 -0.4 -0.5 -0.3 1.0 -0.6 -0.2 0.5 -1.2 -0.2 -0.5 0.1 -0.4 -0.3 -0.4 -0.3 0.6 -1.0 1.1 -0.0 -1.0 1.2 -0.2 -1.0 1.9
Average weekly spirits intake 1.2 1.4 3.5 -1.7 -1.4 -1.6 0.4 -1.5 -1.9 -1.4 -0.7 -1.1 -1.5 -1.4 -1.4 -1.3 -1.1 -1.6 0.2 -1.0 1.1 0.2 -1.1 0.5 -0.7 -0.9 -1.0
Sensitivity / hurt feelings 1.7 2.9 5.6 -2.4 -1.7 -1.6 -1.2 -1.8 -2.0 -1.6 -0.9 -1.9 -1.9 -1.4 -1.4 -1.7 -1.7 -1.7 -1.9 -1.9 1.5 -1.3 -2.0 -0.8 -2.3 -1.7 -1.3
Frequency of depressed mood in last 2 weeks 4.4 6.1 10.8 -3.2 -3.1 -2.4 -2.1 -3.3 -3.2 -2.6 -2.8 -2.0 -3.2 -2.6 -3.2 -2.6 -2.3 -2.4 -1.6 -2.5 2.9 0.2 -0.4 -1.9 -1.4 -2.4 -1.8
Hearing difficulty/problems: Yes 0.2 0.3 2.0 0.4 0.5 0.6 0.5 0.5 0.2 -0.0 -1.4 -0.1 0.6 -0.0 0.1 0.4 0.4 0.6 0.7 0.4 -0.5 -0.1 1.1 1.0 0.1 0.4 0.4
Relative age of first facial hair 0.7 1.5 4.7 0.9 0.8 0.9 2.2 0.5 0.9 1.7 0.8 1.5 0.7 1.4 1.3 1.0 1.2 1.0 1.6 1.0 -0.6 1.3 -0.1 2.1 0.8 1.3 1.7
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 2.4 -0.5 -0.4 -0.3 -0.1 -0.8 -0.6 -0.0 -0.3 -0.4 -0.8 -0.3 -0.6 -0.5 -0.1 -0.3 -0.2 -0.8 0.9 -0.1 -1.5 -0.3 -0.1 -0.1 0.4
Ever used hormone-replacement therapy (HRT) 0.8 1.0 6.4 0.9 0.5 0.9 1.1 0.4 1.3 0.8 0.8 1.0 0.5 0.8 1.4 0.8 1.0 1.1 0.8 0.9 -0.4 0.9 -0.5 1.1 0.6 0.1 2.5
Ever had hysterectomy (womb removed) 0.9 1.0 2.6 -1.4 -0.9 -0.9 -1.6 -1.2 -1.1 -0.7 -0.7 -1.0 -1.1 -1.1 -0.8 -1.0 -0.5 -0.8 -1.4 -1.4 1.0 0.1 -1.4 -0.5 -0.5 -0.4 -0.1
Systolic blood pressure, automated reading 0.7 2.1 5.7 -1.5 -1.3 -1.5 -1.5 -1.3 -1.5 -1.5 -0.7 -1.9 -1.2 -1.8 -1.6 -1.7 -1.3 -1.4 -1.0 -1.8 1.1 -0.9 -0.9 -1.5 -1.4 -0.7 -2.4
Eye problems/disorders: Diabetes related eye disease 1.3 1.5 6.8 0.7 0.6 0.4 1.7 0.2 1.0 1.2 0.8 0.7 0.4 1.1 -0.2 0.9 0.8 0.5 2.6 1.4 -0.3 2.6 1.3 2.1 1.0 0.9 1.0
Angina 0.3 0.4 2.6 -0.6 -0.2 -0.5 -0.3 -0.1 -0.2 -0.2 -0.6 -0.8 -0.3 -0.6 -0.5 -0.4 -0.6 -0.6 -0.7 -0.8 0.2 -0.6 -0.2 -0.9 -0.6 -0.5 -1.6
Medication for hormone replacement therapy 4.3 4.8 7.5 2.4 2.4 2.5 2.4 2.1 2.4 1.8 1.3 2.5 2.0 2.0 2.7 2.4 2.7 2.6 1.6 2.3 -2.0 1.6 0.4 1.9 2.1 2.2 2.6
Vitamin and mineral supplements 1.4 1.9 6.8 1.1 0.9 0.8 1.5 0.9 1.0 1.2 0.8 1.3 1.0 1.6 1.4 1.4 1.4 0.8 1.5 2.3 -1.2 1.8 2.6 1.0 1.5 1.6 0.8
Supplements: Zinc 2.0 2.2 7.3 -1.7 -1.7 -1.2 -1.2 -1.5 -1.8 -1.2 -2.2 -0.8 -1.7 -1.4 -1.7 -1.5 -1.4 -1.1 -1.2 -2.4 2.7 -0.5 -1.1 -1.0 -0.3 -0.5 -0.6
Medication: Co-codamol 0.3 0.3 2.1 -0.3 0.2 -0.2 -0.6 0.1 0.1 -0.2 -0.9 -0.5 -0.3 -0.5 0.0 -0.3 -0.6 -0.2 -1.0 -0.6 0.1 -0.8 -1.5 -0.4 -0.7 -0.4 0.6
Medication: Metformin 0.4 0.5 3.2 0.4 0.4 -0.1 1.0 -0.1 0.3 0.8 0.1 0.3 -0.2 0.5 -0.2 0.4 0.5 -0.0 0.9 0.8 -0.1 1.8 0.2 1.3 0.9 -0.1 1.7
Diabetes (father) 1.3 1.6 6.4 1.6 0.9 1.1 1.9 1.3 1.1 0.8 2.5 1.7 1.4 1.3 2.0 0.7 0.2 1.2 0.7 0.9 -1.2 -1.7 0.3 0.9 -0.1 -0.5 0.9
Diabetes (mother) 0.1 0.2 0.8 -0.2 0.1 0.0 -0.6 0.1 -0.3 0.1 0.0 -0.8 -0.1 -0.5 -0.2 -0.2 -0.0 -0.0 -0.4 -0.9 0.5 -0.8 0.1 -0.9 -0.4 -0.0 0.0
Severe depression (siblings) 0.3 0.3 1.3 -0.3 -0.7 -0.7 0.2 -0.9 -0.1 0.1 0.1 -0.3 -0.8 -0.1 -1.1 -0.6 -0.6 -0.7 0.2 -0.5 0.3 -0.1 0.5 -0.9 0.5 -0.7 -0.7
Pack years adult smoking proportion 0.2 0.2 1.6 -0.3 -0.1 0.3 0.5 -0.3 -0.0 -0.0 -0.5 0.3 -0.3 -0.0 -0.4 0.2 0.3 0.3 0.3 -0.4 0.5 0.6 0.2 1.3 0.4 1.1 0.9
Impedance of leg (right) 0.3 1.5 5.5 -0.9 -0.7 -1.0 -2.2 -1.1 -0.9 -1.1 -0.4 -0.6 -1.0 -1.2 -1.1 -1.2 -0.7 -0.9 -1.7 -1.2 1.4 -0.2 -2.4 -1.3 0.2 -0.5 -2.0
Leg fat-free mass (left) 0.1 0.4 2.9 -0.0 -0.3 -0.5 -0.1 -0.0 -0.1 -0.4 1.3 -0.9 -0.2 -0.3 0.2 -0.4 -0.7 -0.5 -0.2 -0.3 -0.4 -1.1 -0.2 -0.6 -1.7 -0.7 0.4
Trunk fat percentage 0.1 0.4 3.5 -0.0 0.0 -1.0 -0.2 -0.4 -0.1 0.5 1.9 -1.0 -0.5 0.0 -0.2 -0.5 -0.7 -1.0 0.1 -0.2 -0.2 -0.5 -0.6 0.4 -0.9 -1.0 0.2
Hand grip strength (right) 0.1 0.2 1.4 -0.1 -0.0 0.4 0.1 0.3 0.2 -0.4 0.1 -0.2 0.2 -0.2 0.4 0.0 0.2 0.5 -0.8 -0.2 -0.5 -0.6 -1.1 -0.0 -0.6 1.2 -0.3
Townsend deprivation index at recruitment 1.5 2.1 10.2 1.4 0.9 0.9 0.8 0.3 1.1 0.9 -0.6 2.0 0.5 0.8 0.6 1.2 1.7 1.0 2.4 2.0 -0.9 3.2 0.8 1.8 2.5 1.4 1.1
Current tobacco smoking 0.2 0.3 1.5 -0.3 -0.4 -0.4 0.4 -0.5 -0.2 -0.2 -1.0 0.5 -0.6 0.1 0.1 -0.2 0.0 -0.4 0.6 0.0 0.3 1.2 0.7 0.3 0.8 0.2 -0.4
Average weekly fortified wine intake 1.2 1.4 2.2 -1.3 -1.4 -1.1 -1.2 -1.2 -1.2 -1.5 -1.0 -1.2 -1.4 -1.3 -1.2 -1.2 -1.3 -1.2 -0.7 -1.4 1.4 -1.0 -1.0 -1.4 -0.9 -1.0 -1.1
Maternal smoking around birth 0.4 0.5 2.8 0.6 0.1 0.7 0.4 -0.0 0.6 0.5 -0.2 1.6 -0.1 0.7 0.3 0.5 0.5 0.7 1.3 0.7 0.2 1.7 0.0 1.0 1.0 0.2 0.2
Fed-up feelings 0.6 1.1 2.8 -1.4 -1.4 -1.3 0.1 -1.7 -1.1 -0.7 -0.9 -0.5 -1.7 -0.8 -1.4 -0.9 -0.6 -1.3 0.4 -0.4 1.2 1.6 0.4 -0.0 -0.0 -1.5 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 1.2 -0.7 -1.0 -0.3 0.6 -0.8 -0.6 -0.4 -0.4 0.4 -0.7 -0.0 -0.7 -0.5 -0.5 -0.3 0.1 -0.2 0.6 0.7 0.0 -0.2 -0.1 -1.1 -0.3
Relative age voice broke 0.9 1.4 3.1 1.2 1.1 1.1 1.6 0.9 1.2 1.7 1.8 1.5 1.0 1.7 1.3 1.0 0.9 1.1 0.9 1.3 -0.6 0.3 -0.3 1.4 0.8 1.2 1.4
Taking other prescription medications 0.3 0.5 2.6 -0.6 -0.9 -0.4 -0.3 -0.7 -0.6 -0.1 -0.7 -0.5 -0.5 -0.5 -0.5 -0.6 -0.5 -0.3 -0.6 -1.3 1.3 -0.3 -1.6 -0.2 -0.3 -0.8 1.0
Age when periods started (menarche) 1.0 2.3 9.8 1.9 1.8 1.6 -0.4 1.5 1.8 1.6 3.1 1.5 1.4 1.8 0.8 1.7 1.6 1.7 0.2 1.4 -1.0 1.1 -1.9 0.1 0.8 1.7 0.4
Bilateral oophorectomy (both ovaries removed) 1.0 1.2 2.6 -1.0 -1.3 -1.1 -1.6 -1.5 -0.9 -1.3 -0.7 -1.2 -1.2 -1.6 -1.0 -1.2 -1.2 -1.0 -1.2 -1.1 0.7 -0.6 -0.8 -0.3 -1.0 -0.9 0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 3.1 1.2 0.5 0.3 0.7 0.6 1.1 0.9 1.8 1.2 0.7 0.9 1.3 0.3 0.1 0.4 0.8 1.2 -0.8 -0.0 0.1 0.7 -0.4 -0.4 0.7
Tinnitus: Yes, but not now, but have in the past 0.9 0.9 3.2 -1.6 -0.9 -0.6 -0.2 -0.9 -1.3 -0.9 -1.8 -0.6 -0.8 -0.6 -1.2 -0.5 -0.6 -0.6 -1.0 -0.9 1.6 0.7 -0.3 0.6 -1.1 0.2 -1.0
Qualifications: CSEs or equivalent 3.3 4.3 9.5 2.1 2.0 2.4 3.1 2.0 1.9 1.9 0.6 2.9 1.9 2.1 2.2 2.3 2.0 2.5 1.6 2.4 -1.8 1.7 1.9 0.9 2.0 2.8 0.9
Serious illness, injury or assault to yourself 0.3 0.4 1.5 0.5 0.3 0.9 0.7 0.4 0.5 0.5 0.2 0.8 0.6 0.8 0.7 0.6 0.5 1.0 -0.2 0.6 -0.4 -0.1 -1.2 0.8 0.0 0.5 0.5
High blood pressure 0.2 0.5 4.2 -0.4 -0.6 -0.5 0.0 -0.6 -0.4 0.2 -1.5 -0.2 -0.4 -0.4 0.4 -0.4 0.3 -0.4 0.4 -0.1 -0.1 0.9 -0.5 1.2 0.1 -0.6 2.0
Hayfever, allergic rhinitis or eczema 1.3 2.7 9.3 1.7 1.8 1.5 2.0 1.4 1.6 1.9 1.5 1.3 1.3 1.6 1.1 1.9 1.6 1.6 1.3 1.5 -1.4 1.3 3.0 0.9 1.8 1.9 1.6
Multivitamins +/- minerals 0.4 0.4 3.4 -0.3 -0.3 -0.5 -0.7 -0.5 -0.1 -0.4 -0.2 -0.5 -0.5 -0.9 -0.8 -0.8 -0.7 -0.4 -0.2 -0.8 0.6 -0.5 -1.8 -0.6 -0.3 -1.0 -0.5
Stomach or abdominal pain in last month 0.2 0.2 1.1 -0.1 0.3 0.6 0.7 0.5 0.1 0.3 0.8 0.7 0.7 0.5 -0.1 0.5 -0.0 0.7 -0.0 0.3 -0.1 -0.2 -0.1 1.1 0.1 -0.2 -0.1
Supplements: Glucosamine 0.5 0.7 5.4 0.9 0.5 0.6 0.9 0.7 1.1 0.8 2.3 0.4 0.7 1.2 0.4 0.6 0.4 0.6 0.6 0.5 -0.8 -0.2 -0.2 0.4 -0.5 0.8 0.6
Diverticular disease/diverticulitis (self-reported) 0.8 1.0 1.8 -1.4 -1.0 -1.0 -0.7 -1.1 -1.1 -0.7 -0.2 -1.1 -1.2 -1.0 -1.1 -1.0 -0.9 -1.0 -0.4 -1.3 1.4 -0.2 0.1 -1.4 -0.6 -1.1 -1.0
Medication: Atenolol 0.5 0.7 1.7 -1.1 -0.7 -0.9 -0.5 -0.8 -1.0 -0.2 -0.3 -0.9 -0.9 -0.2 -1.2 -0.8 -0.7 -1.0 0.1 -1.0 1.1 0.1 -0.6 -1.2 -0.5 -1.3 -0.1
Medication: Levothyroxine sodium 1.5 2.6 5.8 1.3 1.2 1.9 1.4 1.1 1.4 1.9 0.1 2.2 1.0 1.4 1.5 1.9 1.7 2.0 1.6 1.7 -0.9 2.2 -0.5 1.1 2.2 1.8 2.4
Sitting height 0.1 0.8 2.6 0.3 -0.4 -0.7 -1.4 -0.1 0.4 -1.3 1.3 -0.8 -0.1 -1.0 -0.5 -0.8 -0.5 -0.6 -0.6 -0.0 -0.4 -1.2 -1.6 -1.5 -1.2 0.4 -1.4
Chronic bronchitis/emphysema (father) 2.1 2.5 4.4 -1.6 -2.1 -1.1 -1.4 -1.6 -1.6 -1.7 -1.2 -1.7 -1.4 -1.8 -1.8 -1.6 -1.7 -1.1 -1.1 -2.0 1.6 -1.7 -0.2 -1.5 -1.5 -1.7 -1.9
High blood pressure (mother) 0.2 0.3 1.8 0.3 0.5 0.5 0.3 0.7 -0.2 0.2 0.6 0.5 0.6 0.3 -0.1 0.2 0.1 0.5 -0.1 -0.2 -0.1 -1.3 1.3 -0.3 -0.3 0.5 -0.1
Body mass index (BMI) 0.4 1.8 6.9 1.2 0.9 0.9 2.6 0.9 1.2 2.1 2.0 1.1 0.9 1.9 1.6 1.1 0.8 1.0 1.6 1.3 -1.1 0.5 0.8 1.2 0.2 0.0 2.2
Impedance of leg (left) 0.2 0.7 4.0 -0.4 -0.1 -0.6 -1.7 -0.7 -0.3 -0.6 -0.5 -0.2 -0.6 -0.8 -0.9 -0.7 -0.1 -0.6 -0.9 -0.7 1.0 0.2 -2.0 -0.4 0.9 0.0 -1.8
Leg predicted mass (left) 0.1 0.3 2.6 0.0 -0.2 -0.4 0.0 0.0 -0.0 -0.3 1.3 -0.9 -0.2 -0.2 0.2 -0.3 -0.6 -0.5 -0.1 -0.2 -0.5 -1.0 -0.1 -0.5 -1.6 -0.6 0.3
Trunk fat mass 0.1 0.5 4.0 -0.0 -0.1 -0.9 -0.1 -0.4 -0.1 0.2 2.0 -1.1 -0.5 -0.1 -0.1 -0.6 -0.7 -0.9 -0.1 -0.3 -0.3 -0.7 -1.2 -0.0 -1.2 -1.0 0.2
Waist circumference 0.1 0.5 2.3 -0.4 -0.6 -0.6 1.0 -0.6 -0.3 0.3 0.8 -0.6 -0.6 0.3 0.0 -0.4 -0.6 -0.5 0.7 -0.2 0.1 0.3 -1.5 0.7 -1.2 -1.2 0.9
Number of incorrect matches in round 1.2 2.0 4.1 -1.3 -1.2 -1.8 -0.7 -1.4 -1.1 -1.3 -1.3 -1.7 -1.4 -1.7 -1.0 -1.7 -1.6 -1.9 -1.1 -1.5 1.7 -1.1 -1.5 -1.2 -1.1 -2.0 -0.9
Past tobacco smoking 0.6 1.1 3.7 -0.6 -0.2 -0.9 -1.2 -0.4 -0.2 -0.9 -0.7 -1.3 -0.6 -1.1 -0.4 -0.8 -1.2 -1.1 -1.9 -0.6 0.2 -1.6 0.2 -1.8 -1.0 -0.4 -1.9
Alcohol usually taken with meals 0.2 0.3 2.0 0.0 0.1 -0.1 -0.9 0.2 -0.1 -0.0 0.8 -0.6 0.2 -0.1 0.2 0.1 -0.1 -0.1 -1.1 -0.4 -0.6 -1.4 0.2 -0.3 -0.5 -0.4 -0.2
Nervous feelings 1.3 2.5 5.5 -1.5 -1.9 -1.6 -0.4 -1.5 -1.3 -1.7 -0.7 -1.1 -1.5 -1.1 -1.3 -1.8 -2.3 -1.5 -1.1 -1.4 2.3 -1.5 1.6 -0.9 -2.2 -2.2 -1.6
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.6 -0.6 -0.5 -0.2 0.7 -0.6 -0.4 0.3 -0.8 0.2 -0.6 -0.1 -0.0 -0.0 -0.2 -0.2 -0.1 -0.4 0.6 0.6 -0.2 -0.2 0.7 -1.2 0.5
Hearing difficulty/problems with background noise 0.4 0.6 2.8 -0.9 -0.5 -0.7 -0.2 -0.8 -0.9 -0.7 -1.7 -0.9 -0.8 -0.9 -0.5 -0.7 -0.4 -0.7 -0.0 -1.2 1.1 -0.0 -0.1 1.0 0.2 0.6 0.2
Hair/balding pattern: Pattern 2 0.9 1.1 4.2 -1.4 -0.4 -0.1 -0.9 -0.5 -1.0 -0.5 -0.7 -0.9 -0.5 -0.7 -0.7 -0.4 -0.6 -0.1 -1.9 -1.7 1.5 -1.4 -1.2 -2.1 -0.1 0.6 -1.4
Had menopause 2.6 3.3 5.5 -2.2 -2.3 -2.0 -1.4 -2.1 -1.7 -2.1 -1.6 -2.4 -2.0 -2.0 -1.9 -2.1 -1.8 -1.9 -1.0 -2.1 1.5 -1.1 -1.8 0.2 -1.9 -1.6 -1.1
Had other major operations 0.4 0.5 2.5 0.1 0.3 -0.1 -1.2 0.3 -0.0 -0.4 1.3 -0.9 0.1 -0.3 -0.2 -0.1 -0.4 -0.2 -0.7 -0.3 0.3 -1.1 -0.6 -1.6 -0.5 -0.3 -1.6
Forced vital capacity (FVC) 0.9 3.4 8.3 2.5 1.9 1.8 1.1 2.0 2.4 2.2 1.7 2.4 1.9 2.9 1.7 1.6 1.1 1.7 0.9 2.2 -1.7 0.1 2.4 -0.2 1.1 2.2 1.3
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.8 2.0 1.2 0.5 0.4 0.9 0.4 1.2 1.3 1.2 1.3 0.6 1.0 1.4 0.5 0.6 0.5 1.2 1.1 -0.6 0.9 -0.1 1.1 0.3 0.1 1.3
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 2.0 -0.4 -0.9 0.6 0.6 -0.4 -0.3 0.7 0.9 1.3 -0.2 1.4 0.1 -0.2 -0.3 0.7 -0.5 -0.7 1.3 -0.5 -1.1 0.0 -0.8 -0.3 1.2
Qualifications: None of the above 0.1 0.3 1.7 -0.1 -0.2 -0.1 0.8 -0.5 0.4 -0.1 -0.8 0.4 -0.4 0.1 -0.1 -0.1 0.0 -0.0 0.9 0.4 0.1 1.3 -0.7 0.8 0.3 -0.1 0.8
Financial difficulties in last 2 years 3.0 4.0 9.4 -2.3 -2.1 -2.4 -1.8 -2.6 -1.9 -2.3 -3.1 -2.0 -2.7 -2.5 -2.1 -2.1 -2.1 -2.4 -1.8 -1.9 2.1 0.3 -0.9 -1.0 -0.8 -1.6 0.1
Mouth/teeth dental problems 0.4 0.6 2.0 0.8 0.6 1.2 1.1 1.1 0.5 1.4 0.6 1.1 1.0 1.0 0.9 0.7 0.5 1.2 1.1 0.3 0.4 -0.4 0.5 0.3 0.1 0.1 -0.0
Heart attack 2.2 2.8 4.8 1.6 1.6 1.7 2.2 1.6 1.8 2.1 1.0 2.1 1.7 2.1 1.7 1.7 1.8 1.7 1.6 1.6 -1.2 1.1 -1.0 1.5 1.7 1.2 1.7
Allergy 0.5 1.1 4.4 -1.3 -1.2 -1.0 -1.8 -1.1 -1.2 -1.3 -0.8 -0.6 -1.2 -1.2 -0.6 -1.2 -0.7 -1.0 -0.6 -0.7 1.0 -0.2 -2.1 -0.2 -0.9 -0.9 -0.1
Pain all over the body in last month 0.1 0.1 0.9 -0.1 -0.2 0.2 0.5 -0.1 -0.1 0.4 0.1 0.6 -0.1 0.4 0.1 0.0 0.2 0.2 0.1 -0.1 0.2 0.4 -0.5 0.5 0.6 0.1 1.0
Diabetes (self-reported) 1.2 1.9 4.8 -1.4 -1.3 -2.1 -0.8 -2.2 -1.3 -0.6 -1.5 -1.5 -2.1 -1.3 -1.9 -1.3 -0.9 -2.0 0.7 -0.8 1.3 2.2 -0.5 0.4 0.6 -1.3 -0.2
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 2.7 -0.6 -0.2 -0.4 0.1 -0.7 -0.5 -0.2 -1.6 -0.4 -0.7 -0.7 -0.4 -0.4 -0.4 -0.5 -0.3 -0.9 0.4 -0.1 0.6 -0.0 0.0 -0.1 1.2
Medication: Ramipril 0.2 0.2 2.0 0.2 0.1 0.0 1.4 0.2 -0.0 0.3 0.8 0.1 0.4 0.4 0.7 -0.0 -0.3 0.0 0.5 0.2 -0.4 -0.8 0.2 0.6 -0.4 -0.4 0.4
Medication: Simvastatin 0.1 0.2 1.3 -0.3 -0.3 0.0 0.3 -0.4 -0.3 0.2 0.0 0.2 -0.3 0.1 -0.9 -0.0 0.3 0.1 0.5 -0.2 0.4 1.2 0.1 0.2 0.6 0.1 0.8
Fluid intelligence score 0.3 0.5 1.5 0.9 1.0 0.3 0.4 0.9 0.9 0.9 0.5 0.5 0.8 0.8 0.3 0.7 0.6 0.2 0.6 0.8 -1.2 0.0 1.1 -0.2 1.0 0.7 0.2
Illnesses of siblings 0.4 0.6 4.3 0.3 0.6 -0.2 0.2 0.1 0.6 0.5 -1.3 0.6 -0.2 0.4 0.2 0.4 0.8 -0.3 0.8 1.1 -0.8 2.1 0.7 0.1 1.6 0.7 0.5
Neuroticism score 2.8 5.9 11.6 -3.3 -3.0 -2.6 -1.6 -3.0 -3.0 -2.1 -2.2 -2.3 -3.0 -2.2 -2.7 -2.7 -2.4 -2.6 -1.8 -3.0 3.4 -0.7 0.6 -1.7 -1.7 -2.4 -1.8
Weight 0.1 0.4 3.3 0.2 -0.0 -0.2 0.4 0.1 0.2 0.3 1.8 -0.6 -0.0 0.2 0.6 -0.1 -0.3 -0.2 0.0 -0.2 -0.5 -0.9 -1.1 -0.1 -1.3 -0.6 0.8
Impedance of arm (right) 0.8 3.6 17.1 -1.5 -1.3 -2.1 -4.1 -1.7 -1.8 -2.1 -0.4 -2.0 -1.6 -2.3 -2.1 -2.0 -1.8 -2.0 -2.2 -1.8 1.5 -1.1 -1.4 -1.8 -1.1 -1.4 -1.8
Arm fat percentage (right) 0.1 0.5 3.6 0.3 0.1 -0.2 1.1 -0.1 0.1 1.3 1.9 -0.0 -0.0 1.0 0.5 0.1 -0.2 -0.1 0.5 0.2 -0.3 -0.1 -0.1 0.6 -0.6 -0.8 1.6
Trunk fat-free mass 0.1 0.7 5.6 -0.6 -0.7 -0.4 -0.2 -0.4 -0.5 -1.1 0.3 -1.2 -0.5 -1.0 -0.1 -0.6 -0.4 -0.4 -0.8 -1.0 0.0 -0.9 -2.4 -1.1 -1.5 -0.4 -0.0
Hip circumference 0.1 0.4 3.2 0.4 0.4 0.1 0.9 0.2 0.4 1.1 1.8 -0.0 0.1 0.7 0.4 0.3 0.3 0.2 0.7 -0.1 -0.5 -0.1 -0.3 0.3 -0.4 0.2 1.0
Time employed in main current job 0.3 0.4 1.9 0.4 0.6 0.3 1.4 0.6 0.1 0.8 0.6 -0.3 0.7 0.6 0.8 0.4 -0.1 0.2 0.4 0.2 -0.9 -0.7 1.0 0.0 -0.0 -0.9 0.2
Alcohol intake versus 10 years previously 1.4 2.1 4.4 1.4 1.6 1.4 1.4 1.1 1.3 1.3 0.4 1.3 1.0 1.3 1.1 1.7 1.9 1.3 1.7 1.9 -1.4 2.0 0.3 1.8 1.5 2.1 0.5
Father’s age at death 0.8 1.1 5.4 1.2 1.1 0.6 -0.5 1.3 1.1 0.4 2.3 -0.1 1.5 0.6 0.7 0.6 0.6 0.5 -0.5 0.6 -1.8 -1.6 0.4 -1.5 -0.1 0.4 -0.6
Worrier / anxious feelings 1.6 3.1 5.2 -1.8 -1.7 -1.9 -1.6 -1.7 -2.0 -1.5 -0.2 -1.9 -1.4 -1.7 -1.5 -2.1 -2.2 -1.9 -2.0 -2.0 1.5 -2.3 0.1 -1.0 -2.3 -2.0 -2.0
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.5 -0.5 -0.4 0.1 0.5 -0.5 -0.4 0.5 -0.5 0.9 -0.5 0.4 0.0 -0.1 -0.1 0.2 0.2 -0.8 1.1 0.4 -1.2 -0.2 0.4 -1.1 0.4
Falls in the last year 0.3 0.3 2.0 0.2 -0.7 -0.6 -0.0 -0.4 0.3 0.4 1.1 0.1 -0.4 -0.0 0.3 -0.6 -0.7 -0.5 0.8 -0.5 0.8 -0.1 -1.4 0.0 -0.3 -0.7 -0.1
Hair/balding pattern: Pattern 3 0.2 0.3 2.6 0.2 -0.4 0.1 0.7 -0.1 0.4 0.1 -0.4 0.6 -0.1 0.1 -0.0 0.1 0.1 0.1 1.0 0.0 0.3 0.5 -0.7 -0.0 0.6 -1.6 -0.2
Number of live births 0.3 0.5 5.3 0.6 0.2 0.0 -0.7 0.4 0.9 0.2 1.3 0.1 0.3 0.2 0.2 -0.2 -0.2 -0.0 0.5 0.1 -0.1 -0.8 -0.4 -2.3 0.2 0.1 -1.2
Forced expiratory volume in 1-second (FEV1) 1.5 5.0 13.5 2.9 2.1 2.2 1.9 2.2 2.5 3.3 2.1 3.3 2.0 3.7 2.1 2.0 1.3 2.1 1.6 2.5 -1.3 0.8 2.6 0.2 1.6 2.3 1.9
Pulse rate 0.5 0.9 2.4 -0.9 -0.9 -1.1 -0.4 -1.2 -1.2 -0.9 -0.6 -0.8 -1.3 -1.0 -1.2 -1.0 -1.1 -1.0 -0.0 -1.1 1.5 0.1 0.6 -0.1 -0.8 -1.0 -0.5
Happiness 0.7 0.8 3.9 -1.0 -1.3 -0.7 -0.0 -1.2 -0.9 -0.3 -1.2 -0.1 -1.3 -0.6 -1.3 -0.7 -0.5 -0.7 0.5 -0.7 1.1 0.9 -0.1 -0.6 0.3 -2.0 -0.7
Noisy workplace 1.3 1.6 5.3 0.8 0.6 1.1 1.9 0.5 0.8 1.3 -0.5 1.2 0.6 1.1 0.7 0.9 1.4 1.2 1.7 0.9 0.0 2.0 1.1 2.3 1.5 1.8 1.2
Qualifications: A levels/AS levels or equivalent 0.1 0.3 2.8 0.4 0.6 0.6 0.2 0.5 -0.1 0.9 1.7 0.3 0.6 0.6 0.5 0.5 0.4 0.6 0.1 0.3 -0.5 -0.5 0.0 -0.1 -0.4 -0.5 0.6
Serious illness, injury or assault of a close relative in last 2 years 1.4 1.6 3.0 1.5 1.2 1.6 1.5 1.3 1.3 1.1 1.4 1.6 1.3 1.6 1.2 1.6 0.9 1.7 0.5 1.4 -1.0 0.4 0.0 1.6 0.4 1.6 0.4
Mouth/teeth dental problems: Dentures 0.4 0.7 3.5 0.2 0.3 1.0 0.6 0.5 0.6 0.2 0.3 0.8 0.3 0.5 0.4 0.9 1.1 1.0 0.6 0.4 -0.5 1.1 -0.4 1.8 0.3 1.0 1.9
Asthma 0.1 0.3 1.3 0.2 0.3 -0.0 0.5 0.2 0.4 0.3 0.4 -0.9 0.5 0.2 0.3 0.0 -0.3 -0.0 -1.0 -0.4 -0.6 -0.8 -1.1 -0.5 -0.6 0.4 -0.5
Medication: Ibuprofen (e.g. Nurofen) 1.0 1.2 4.9 1.2 1.0 1.0 1.5 1.0 1.1 2.0 0.9 1.3 0.9 2.2 1.2 1.1 0.7 1.0 0.9 0.7 0.1 0.4 -0.9 1.1 0.7 0.6 1.0
Medication: Cholesterol lowering 0.3 0.5 1.8 -0.9 -0.7 -0.4 -0.6 -0.7 -0.6 -0.5 -0.6 -0.9 -0.6 -0.8 -1.3 -0.4 -0.2 -0.4 -0.2 -0.9 0.7 0.4 -1.2 -0.1 -0.7 -0.2 -0.6
Depression (self-reported) 2.2 2.6 8.2 -1.8 -2.2 -1.2 -0.9 -2.0 -1.9 -1.2 -2.0 -0.7 -2.0 -1.6 -1.6 -1.8 -1.5 -1.1 -0.8 -2.2 2.9 -0.5 -1.2 0.2 -1.6 -2.1 -0.6
Medication: Lansoprazole 3.2 3.6 6.5 -1.8 -2.0 -2.4 -1.6 -2.1 -2.0 -2.1 -2.4 -1.9 -2.1 -1.9 -2.0 -2.3 -2.5 -2.3 -1.7 -1.6 1.8 -1.1 0.2 -0.9 -1.8 -2.4 -0.7
Prospective memory result 0.6 0.8 4.7 -0.8 -0.8 -0.8 -0.7 -0.8 -0.6 -0.8 -1.8 -0.5 -0.8 -0.5 -1.1 -0.8 -0.8 -0.8 0.1 -0.3 1.0 0.2 -1.0 -0.4 -0.6 0.1 -2.2
Lung cancer (father) 0.2 0.3 2.0 0.2 -0.9 0.1 0.3 -0.3 0.3 -0.1 0.1 -0.1 -0.3 0.3 -0.1 -0.3 -0.5 0.3 0.1 0.2 0.5 -0.4 -0.8 0.7 -1.4 -0.4 1.2
Illnesses of mother 0.3 0.4 1.7 -0.1 -1.0 -0.9 -0.6 -0.9 -0.2 -0.8 -1.3 -0.4 -0.8 -1.0 -0.4 -0.8 -0.8 -0.8 0.1 -0.1 0.3 0.6 -0.3 -0.1 -0.3 -0.6 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.9 6.0 13.5 3.2 2.4 2.4 2.1 2.4 2.9 3.3 2.1 3.7 2.3 3.7 2.2 2.2 1.6 2.4 1.9 2.6 -1.7 0.7 2.9 0.4 1.8 2.5 2.3
Pulse wave Arterial Stiffness index 2.8 3.2 5.8 1.9 1.7 1.8 1.9 1.8 1.5 2.4 2.0 1.8 1.9 2.0 2.2 1.7 2.1 2.0 2.2 1.3 -1.0 1.0 0.4 2.3 1.6 2.0 1.4
Impedance of arm (left) 0.7 3.1 14.3 -1.3 -1.2 -2.1 -3.8 -1.5 -1.5 -1.9 -0.4 -1.9 -1.5 -2.2 -1.7 -2.0 -1.9 -2.1 -1.9 -1.5 1.3 -1.4 -1.0 -1.3 -1.1 -1.4 -2.2
Arm fat mass (right) 0.1 0.4 3.6 0.3 0.2 -0.0 1.0 0.1 0.2 1.0 1.9 -0.1 0.1 0.8 0.6 0.1 -0.0 0.0 0.4 0.1 -0.5 -0.3 -0.3 0.3 -0.6 -0.5 1.4
Trunk predicted mass 0.1 0.7 5.6 -0.5 -0.6 -0.4 -0.1 -0.3 -0.4 -1.0 0.4 -1.1 -0.4 -0.9 -0.0 -0.5 -0.4 -0.4 -0.8 -0.9 -0.0 -0.9 -2.4 -1.0 -1.4 -0.3 0.1
Standing height 0.9 9.4 23.8 -2.5 -2.1 -2.7 -4.9 -2.0 -2.5 -4.1 -0.3 -4.0 -2.2 -4.1 -2.5 -2.9 -2.5 -2.8 -3.5 -3.5 1.7 -3.0 -4.5 -3.1 -3.4 -1.3 -3.3
Length of working week for main job 0.5 0.6 1.9 -0.9 -0.3 -0.9 -1.4 -0.5 -0.6 -0.5 0.0 -1.3 -0.7 -0.6 -0.5 -0.5 -0.7 -1.0 -0.8 -0.9 1.0 -0.2 0.1 -0.6 -0.0 -0.4 -1.4
Exposure to tobacco smoke at home 4.0 4.5 7.1 2.2 2.1 2.4 1.7 2.1 2.2 2.0 0.9 2.7 2.0 2.2 2.5 2.4 2.4 2.4 2.2 2.3 -2.0 1.6 1.8 2.0 2.3 2.0 2.1
Breastfed as a baby 2.1 2.6 9.1 -2.2 -1.2 -1.7 -1.9 -1.3 -2.0 -2.0 -0.2 -2.2 -1.3 -1.5 -2.0 -1.4 -1.3 -1.8 -0.5 -1.9 1.6 -0.6 -1.1 -0.0 -1.1 -0.3 -3.0
Tense / ‘highly strung’ 0.4 0.7 1.9 -1.0 -1.1 -1.0 -0.3 -1.3 -0.5 -0.6 -1.4 -0.4 -1.2 -0.7 -0.5 -1.0 -1.0 -0.9 -1.0 -0.9 1.3 0.2 -0.8 -0.3 -0.6 -0.6 0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.1 0.2 1.3 -0.3 -0.5 -0.2 0.1 -0.8 -0.2 0.2 0.3 0.3 -0.7 0.2 -0.4 -0.3 -0.4 -0.1 -0.1 -0.7 1.2 0.1 0.2 -0.3 0.7 -0.0 0.4
Hair/balding pattern: Pattern 4 0.3 0.7 3.2 -0.3 -0.7 -1.0 -1.0 -0.5 0.1 -0.6 -1.7 -0.7 -0.5 -0.3 -0.4 -0.9 -0.9 -0.9 -1.4 0.1 0.2 -0.1 1.0 -0.9 -0.6 -1.8 -0.7
Birth weight of first child 0.1 0.2 1.3 -0.3 -0.1 -0.3 -0.8 -0.1 -0.2 -0.3 -0.5 -0.5 -0.1 -0.6 -0.3 -0.2 -0.3 -0.4 -1.1 -0.3 0.2 0.0 -0.0 -0.6 -0.2 0.4 -1.2
Peak expiratory flow (PEF) 0.2 0.6 2.9 1.1 0.3 0.5 0.8 0.7 0.6 1.2 1.7 1.0 0.6 1.7 0.3 0.4 -0.3 0.5 0.2 0.5 0.1 -0.4 -0.1 0.0 -0.3 0.7 0.2
Pulse wave reflection index 3.4 4.2 7.6 2.2 2.1 2.2 2.0 2.2 2.2 2.4 1.6 2.0 2.4 2.4 2.8 2.0 2.3 2.3 1.8 1.8 -1.8 0.8 0.3 2.2 1.8 2.3 1.9
Ever highly irritable/argumentative for 2 days 0.2 0.3 1.5 0.3 0.2 0.5 0.1 0.6 -0.2 0.7 0.6 0.2 0.5 0.7 0.9 0.1 -0.2 0.6 -0.3 -0.2 0.3 -1.2 0.6 -0.3 -0.7 -0.1 -0.3
Loud music exposure frequency 0.4 0.5 2.6 0.1 -0.7 0.4 1.3 -0.3 0.1 0.1 -0.9 1.2 -0.0 0.3 0.6 -0.2 0.0 0.5 1.1 -0.6 0.8 -0.1 0.5 0.7 0.3 0.3 1.6
Qualifications: O levels/GCSEs or equivalent 1.7 2.6 5.2 1.9 2.0 1.6 1.2 1.9 1.2 1.9 2.3 1.5 1.9 1.9 1.8 1.5 1.5 1.5 0.4 1.5 -1.7 -0.8 2.1 0.7 0.8 2.2 1.5
Mouth/teeth dental problems: Bleeding gums 0.3 0.3 1.8 0.3 0.6 -0.3 -0.5 0.2 0.2 0.0 0.8 -0.1 0.4 -0.1 0.1 0.0 0.1 -0.3 -1.2 0.4 -1.4 -0.5 -1.0 -1.1 0.4 -0.4 0.1
Blood clot in the leg (DVT) 0.2 0.3 1.6 0.3 -0.1 0.6 1.1 0.6 0.2 0.3 -0.5 0.6 0.4 0.7 0.1 0.4 0.2 0.5 0.9 0.3 0.1 -0.1 1.3 0.3 0.1 -0.2 -0.1
Medication: Paracetamol 0.2 0.4 1.3 -0.6 -0.9 -0.6 0.1 -0.8 -0.4 0.2 -0.3 0.0 -0.7 0.2 -0.3 -0.8 -1.1 -0.5 0.1 -0.6 0.9 -0.6 -0.1 -0.3 -1.2 -1.1 -0.2
Headache pain in last month 0.5 0.8 2.2 1.0 1.0 0.7 0.6 0.4 1.0 1.2 0.1 1.5 0.6 1.3 0.3 0.8 0.5 0.9 0.4 1.3 -0.8 1.1 1.0 0.6 0.7 1.1 0.7
Medication for cholesterol, blood pressure or diabetes 0.3 0.6 1.9 0.8 0.5 0.7 1.2 0.8 0.8 0.8 0.9 1.1 0.8 1.0 1.4 0.5 0.2 0.7 0.1 0.6 -0.5 -0.9 0.7 -0.1 0.5 0.5 0.2
Glaucoma (self-reported) 1.4 1.7 4.2 1.3 1.0 1.1 2.0 1.2 1.2 1.2 0.5 1.1 1.2 0.9 1.4 1.3 1.5 1.1 1.4 2.1 -1.7 1.6 1.5 1.0 1.3 1.1 0.2
Gout (self-reported) 0.2 0.3 1.7 0.1 -0.3 0.0 -0.5 0.1 -0.0 -0.1 0.5 0.1 0.2 0.2 -0.2 -0.3 -0.7 -0.0 -0.3 -0.3 0.1 -1.3 1.2 -0.8 -1.1 -1.3 -0.2
Hypothyroidism/myxoedema (self-reported) 1.3 2.6 7.2 1.5 1.3 2.2 1.7 1.6 1.4 1.8 0.6 2.4 1.4 1.7 1.5 1.9 1.5 2.2 1.5 1.8 -1.1 1.0 0.6 0.4 1.4 1.1 2.7
Medication: Amlodipine 0.1 0.2 1.2 -0.2 -0.4 -0.3 -0.5 -0.3 0.1 0.4 0.2 -0.3 -0.2 0.1 -0.6 -0.4 -0.0 -0.2 0.7 -0.3 0.2 0.5 -0.8 1.1 -0.7 0.6 0.1
Medication: Ventolin 100micrograms inhaler 0.3 0.4 3.1 -0.0 0.3 -0.4 -0.7 -0.2 0.1 0.2 0.9 -1.0 0.1 -0.2 -0.4 0.2 0.4 -0.4 -0.3 -0.2 -0.4 1.2 -1.8 -0.3 1.1 0.7 -0.5
Birth weight 0.3 0.6 3.6 -0.5 0.3 0.2 -1.4 0.5 -0.4 -1.0 -0.4 -0.7 0.6 -0.9 -0.4 0.1 0.1 0.1 -1.9 -0.8 -0.9 -1.5 -0.7 -0.3 -0.9 0.9 -0.3
Chronic bronchitis/emphysema (mother) 0.2 0.2 1.3 0.3 0.1 0.1 0.5 0.1 0.5 0.0 1.2 0.3 0.1 0.4 0.4 0.1 0.1 0.1 0.6 0.9 -0.3 0.3 -0.4 -0.3 0.5 0.3 -0.9
High blood pressure (siblings) 0.8 1.1 5.5 -0.8 -1.0 -0.6 -0.7 -0.6 -0.8 -1.0 0.7 -1.3 -0.4 -0.9 -0.9 -1.1 -1.4 -0.6 -1.2 -1.5 1.1 -2.4 -0.2 -0.4 -1.8 -0.5 -0.8
Forced vital capacity (FVC), Best measure 0.9 3.4 6.8 2.6 2.0 1.7 0.9 2.0 2.6 2.0 1.6 2.5 2.0 2.5 1.5 1.6 1.3 1.7 1.1 2.2 -1.8 0.2 2.1 -0.2 1.2 2.5 1.4
Body fat percentage 0.1 0.4 4.0 0.2 0.0 -0.6 0.6 -0.3 0.2 0.9 2.0 -0.5 -0.3 0.5 0.1 -0.3 -0.5 -0.5 0.4 0.1 -0.1 -0.3 -0.7 0.6 -0.7 -1.0 0.6
Leg fat percentage (right) 0.2 0.7 4.5 0.4 0.0 0.1 1.6 -0.2 0.5 1.5 2.1 0.3 -0.1 1.2 0.7 0.1 -0.0 0.2 0.6 0.3 0.2 0.2 -1.3 0.3 -0.3 -1.0 1.1
Arm fat-free mass (right) 0.1 0.3 1.8 0.1 0.1 -0.0 0.3 0.3 0.3 -0.4 0.8 -0.9 0.2 -0.3 0.3 0.0 -0.1 -0.1 -0.4 -0.2 -0.8 -1.1 -1.3 -0.4 -1.3 0.1 -0.3
Exposure to tobacco smoke outside home 0.2 0.3 1.2 0.4 0.3 0.4 0.1 0.2 0.3 0.4 -0.9 0.5 0.3 0.3 0.6 0.4 0.5 0.4 0.7 0.5 -0.5 0.5 1.1 0.4 1.0 0.2 0.6
Comparative body size at age 10 0.1 0.3 2.3 -0.4 -0.3 -0.2 0.7 -0.1 -0.2 -0.8 -1.0 -0.2 -0.1 -0.4 0.0 -0.1 -0.2 -0.2 0.4 0.2 -0.1 0.4 1.3 0.7 0.3 0.5 1.5
Number of full brothers 0.4 0.5 2.5 0.1 -0.3 0.8 1.6 0.2 0.0 0.8 0.6 0.8 0.3 1.0 1.1 0.4 0.3 0.8 1.0 0.2 0.5 0.1 0.2 0.6 -0.3 -0.6 1.2
Worry too long after embarrassment 2.5 4.1 8.0 -2.7 -2.2 -2.4 -1.8 -2.1 -2.5 -2.0 -0.7 -2.8 -2.0 -2.0 -1.8 -2.2 -1.9 -2.4 -1.8 -2.5 2.1 -1.5 -1.0 -0.9 -1.5 -2.1 -2.3
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.6 4.7 -1.4 -1.2 -1.2 -1.8 -1.6 -1.4 -1.1 -1.4 -0.5 -1.6 -1.2 -1.7 -1.3 -1.1 -1.1 -0.9 -1.7 2.2 -0.2 0.7 -1.2 -0.2 -1.4 -0.1
Wheeze or whistling in the chest in last year 0.6 1.0 3.8 0.8 0.4 0.6 1.8 0.2 1.1 1.1 0.6 1.3 0.2 1.3 0.4 0.7 1.0 0.7 1.4 1.0 -0.7 1.9 -0.6 0.8 1.3 0.5 0.9
Number of children fathered 1.3 1.5 3.2 1.6 1.3 1.1 0.7 1.5 1.8 1.4 1.5 1.1 1.5 1.1 1.2 1.3 1.2 1.1 1.0 1.3 -1.1 0.3 0.0 0.4 1.7 0.9 0.9
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 1.5 0.6 0.6 -0.1 -0.3 0.4 1.0 0.2 1.0 -0.5 0.2 0.2 -0.1 0.2 0.1 -0.2 0.5 0.6 -0.7 0.1 0.8 0.5 0.2 1.2 -0.0
Age at first live birth 0.3 0.5 2.1 0.6 0.6 0.4 0.5 0.8 0.7 0.3 1.3 -0.2 0.9 0.7 0.2 0.6 0.2 0.4 -0.5 0.7 -1.4 -0.9 -1.3 0.5 -0.7 0.3 0.7
Pulse wave peak to peak time 3.9 4.6 7.6 -2.3 -2.1 -2.2 -2.1 -2.2 -1.9 -2.8 -2.3 -2.2 -2.3 -2.4 -2.6 -2.1 -2.5 -2.4 -2.4 -1.7 1.5 -1.2 -0.7 -2.5 -2.0 -2.3 -1.7
Health satisfaction 0.3 0.3 2.4 -0.6 -0.6 -0.5 -0.5 -0.6 -0.8 -0.1 -0.4 -0.3 -0.7 -0.5 -0.4 -0.5 -0.4 -0.5 -0.0 -0.6 0.6 0.2 -0.3 -0.8 0.1 -1.5 -0.3
Shortness of breath walking on level ground 1.3 1.5 6.2 -0.8 -1.5 -1.3 -0.7 -1.4 -1.0 -0.4 0.4 -0.6 -1.4 -0.5 -1.1 -1.7 -1.6 -1.3 -0.1 -1.6 1.6 -1.3 -0.4 -1.3 -1.0 -2.5 -0.9
Qualifications: College or University degree 0.2 0.7 3.2 -0.3 0.1 -0.1 -1.6 0.2 -0.1 -0.8 1.3 -0.8 0.2 -0.6 -0.3 -0.1 -0.5 -0.2 -1.5 -0.7 -0.0 -1.8 -0.0 -1.1 -0.9 -0.8 -1.3
Eye problems/disorders: None of the above 0.2 0.3 1.3 0.3 0.1 0.0 -0.2 0.4 0.2 0.0 0.1 0.1 0.1 0.5 0.4 -0.0 -0.7 -0.0 -0.6 -0.1 0.1 -1.1 0.6 -0.6 -0.9 -1.1 0.5
Mouth/teeth dental problems: Loose teeth 2.0 2.4 5.0 -1.8 -1.4 -2.1 -1.0 -1.9 -1.8 -1.8 -1.3 -1.7 -1.9 -1.6 -2.2 -1.7 -1.6 -2.1 -0.7 -1.8 1.5 0.0 1.0 -1.1 -0.6 -1.3 -1.0
Emphysema/chronic bronchitis 1.0 1.1 3.5 1.3 0.7 1.2 1.9 1.1 1.0 1.1 1.1 1.5 1.3 1.2 1.1 1.0 0.7 1.2 1.6 0.8 -0.8 0.3 0.5 0.6 0.9 0.6 0.3
Medication for pain relief, constipation, heartburn 0.8 1.4 5.5 -0.7 -0.7 -1.1 -2.0 -0.4 -0.9 -1.9 0.8 -1.5 -0.5 -1.8 -1.1 -1.0 -0.8 -1.2 -1.0 -0.5 -0.4 -1.3 0.5 -1.4 -1.1 -0.3 -2.3
Neck or shoulder pain in last month 0.1 0.2 1.1 -0.2 -0.7 -0.3 0.2 -0.6 -0.5 0.1 -0.9 0.2 -0.6 -0.2 0.4 -0.5 -0.6 -0.2 0.5 -0.2 1.1 0.1 0.4 -0.0 -0.1 -0.3 0.3
Medication: Blood pressure 0.2 0.3 1.2 -0.4 -0.3 -0.6 -1.0 -0.5 -0.5 -0.5 -1.1 -0.9 -0.5 -0.7 -0.7 -0.4 -0.2 -0.5 0.0 -0.5 0.2 0.4 -0.0 0.3 -0.7 -1.0 0.4
Angina (self-reported) 0.5 0.7 3.4 -0.9 -0.5 -0.8 -0.6 -0.5 -0.6 -0.4 -0.8 -1.0 -0.6 -0.8 -0.9 -0.7 -0.7 -0.9 -0.8 -1.1 0.5 -0.6 -0.4 -1.1 -0.7 -0.6 -1.8
Migraine (self-reported) 0.3 0.3 2.6 0.2 -0.3 -0.4 -0.7 -0.0 0.2 0.0 1.1 -0.2 0.1 0.1 0.0 -0.6 -0.6 -0.3 0.1 -0.4 0.4 -1.0 -0.9 0.1 -1.6 0.1 -0.6
Medication: Ibuprofen 0.2 0.3 1.4 0.3 0.2 0.0 0.6 0.1 0.4 1.1 0.2 0.1 0.1 1.2 0.4 0.2 -0.0 -0.1 0.5 -0.0 0.7 0.2 -0.9 1.0 0.4 0.0 0.4
Medication: Allopurinol 0.1 0.2 1.3 -0.3 -0.3 0.2 -0.3 -0.1 -0.5 -0.1 0.3 0.1 0.1 -0.0 -0.8 -0.0 -0.1 0.2 -0.1 -0.1 0.3 0.1 1.1 -0.7 -0.3 -0.4 -0.7
Medication: Omeprazole 0.5 0.6 1.4 0.4 0.7 0.6 1.1 0.4 0.7 0.4 -1.1 0.7 0.4 0.1 0.8 0.7 0.6 0.7 0.9 0.7 -0.3 0.8 -0.9 1.2 1.0 0.7 1.0
Medication: Seretide 50 evohaler 0.9 1.0 5.3 0.3 0.8 1.1 1.3 0.4 0.5 0.5 0.4 0.2 0.6 0.2 0.2 1.4 1.7 1.2 0.7 0.7 -0.5 2.3 -1.6 1.1 1.2 1.2 0.5
Mean time to correctly identify matches 0.1 0.2 0.8 -0.2 -0.1 -0.2 -0.5 -0.2 -0.4 -0.1 -0.4 -0.9 -0.1 -0.4 -0.3 -0.3 0.0 -0.2 -0.3 -0.6 0.7 -0.5 -0.8 -0.1 -0.1 -0.4 -0.7
Heart disease (mother) 0.6 0.7 2.8 -1.3 -0.7 -0.9 -0.4 -0.9 -0.8 -0.9 0.3 -1.4 -1.0 -0.9 -1.7 -0.7 -0.4 -0.9 -0.5 -1.3 0.8 -0.3 -0.2 0.2 -0.9 -0.7 -0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.2 7.0 0.7 1.0 1.0 1.1 0.6 0.5 1.3 0.1 0.9 0.6 0.8 1.1 1.3 1.6 1.0 1.0 1.2 -0.5 2.7 0.3 1.1 1.4 0.7 1.3
Whole body fat mass 0.1 0.4 3.5 -0.0 -0.1 -0.7 0.4 -0.3 -0.0 0.5 1.9 -0.8 -0.4 0.2 0.1 -0.4 -0.6 -0.6 0.1 -0.2 -0.2 -0.6 -0.9 0.2 -1.1 -1.0 0.6
Leg fat mass (right) 0.2 0.7 5.2 0.7 0.4 0.3 1.4 0.3 0.8 1.3 2.3 0.2 0.3 1.1 1.0 0.4 0.1 0.4 0.7 0.5 -0.5 0.0 -0.9 0.3 -0.4 -0.5 1.3
Arm predicted mass (right) 0.1 0.4 1.5 0.5 0.4 0.3 0.7 0.6 0.7 -0.1 1.1 -0.5 0.6 0.1 0.7 0.3 0.1 0.2 -0.2 0.1 -1.1 -1.1 -1.2 -0.3 -1.1 0.3 0.0
Pulse rate, automated reading 1.2 3.8 6.6 -2.0 -1.8 -2.5 -1.6 -2.4 -1.9 -2.4 -1.3 -2.6 -2.3 -2.5 -2.1 -2.0 -1.9 -2.4 -1.4 -1.6 1.5 -0.3 -2.1 -0.3 -1.5 -2.2 -2.1
Alcohol intake frequency. 1.3 3.0 5.4 -2.2 -1.7 -2.0 -1.5 -2.3 -2.0 -1.9 -2.3 -1.8 -2.3 -2.0 -1.4 -1.9 -1.8 -2.0 -1.2 -1.8 1.8 -0.2 -0.6 -0.9 -0.8 -1.4 -1.2
Comparative height size at age 10 2.3 12.8 23.2 -3.6 -3.1 -3.5 -4.6 -2.8 -3.5 -4.7 -2.9 -4.7 -2.9 -4.8 -3.6 -3.7 -3.3 -3.8 -3.7 -4.4 2.2 -3.4 -3.0 -2.6 -4.0 -2.1 -3.2
Number of full sisters 1.2 1.4 8.5 0.5 0.6 0.6 1.2 0.3 0.5 1.1 -0.1 1.3 0.3 1.1 0.1 1.0 1.3 0.7 1.9 1.2 -0.2 2.9 1.8 0.5 2.5 1.0 0.5
Suffer from ‘nerves’ 0.9 1.4 3.4 -1.4 -1.6 -1.1 -0.3 -1.2 -1.5 -1.1 -0.2 -0.5 -1.2 -0.6 -1.0 -1.4 -1.4 -1.0 -1.1 -1.5 1.7 -0.9 1.9 -0.6 -1.1 -1.4 -0.6
Overall health rating 0.2 0.4 1.5 -0.8 -0.5 -0.7 0.4 -0.9 -0.7 0.3 -0.3 0.1 -0.7 -0.1 -0.4 -0.5 -0.1 -0.6 -0.0 -0.8 1.2 1.1 -0.8 0.3 0.5 -0.8 -0.0
Chest pain or discomfort 0.3 0.5 1.9 -1.2 -0.8 -0.6 0.5 -0.8 -0.9 -0.4 -1.4 -0.3 -0.9 -0.5 -0.6 -0.6 -0.5 -0.6 -0.3 -0.9 0.9 0.5 -0.8 0.0 -0.1 -0.3 0.4
Had major operations 1.1 1.3 10.5 -1.0 -0.3 -0.7 -1.5 -0.6 -0.9 -1.0 -0.1 -1.9 -0.7 -1.2 -0.4 -0.7 -0.5 -0.7 -1.5 -1.3 0.7 -0.5 -3.2 -0.8 -1.4 -0.1 0.1
Age at last live birth 0.2 0.3 1.2 0.6 0.4 0.4 0.6 0.7 0.5 0.3 1.0 0.3 0.7 0.4 0.5 0.3 0.4 0.3 0.5 0.9 -1.1 -0.4 -0.8 0.1 0.1 0.4 0.5
Family relationship satisfaction 0.1 0.2 1.5 -0.4 0.0 0.1 -0.3 0.0 -0.3 -0.0 -0.1 -0.5 0.0 -0.3 -0.2 0.2 0.4 0.1 -0.5 -0.4 -0.4 0.3 -1.2 -0.8 0.1 -0.2 -0.8
Leg pain on walking 0.4 0.5 1.9 -0.8 -0.4 -1.2 -1.4 -0.8 -0.8 -0.6 -0.9 -0.8 -0.8 -0.9 -0.2 -0.9 -0.4 -1.2 -0.0 -0.7 0.2 -0.2 -0.9 0.7 -0.3 -0.5 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 2.4 -0.9 -0.9 -0.7 0.0 -0.7 -1.2 -1.0 -1.6 -0.8 -0.7 -1.0 -0.3 -0.9 -1.1 -0.6 -1.0 -1.1 1.1 -0.8 0.4 -0.5 -1.1 -0.7 -0.2
Commuting to job workplace: Car/motor vehicle 2.8 3.3 6.4 -1.6 -1.8 -2.4 -2.0 -2.0 -1.3 -1.9 -0.3 -2.5 -2.0 -1.8 -1.9 -2.3 -1.9 -2.4 -1.1 -1.7 1.2 -0.9 -0.9 -2.5 -1.0 -1.7 -2.1
Illness, injury, bereavement, stress in last 2 years 0.6 0.8 1.7 0.7 1.3 0.6 0.1 1.3 0.6 1.1 1.2 0.3 1.2 0.8 0.9 0.9 1.2 0.4 0.9 0.7 -1.3 0.1 1.0 -0.4 0.9 1.1 -0.5
Medication: Aspirin 0.2 0.3 2.4 0.0 0.4 0.7 0.8 0.2 0.1 0.8 0.0 0.4 0.3 0.6 0.4 0.7 0.6 0.8 0.0 -0.1 0.0 0.7 0.2 0.2 0.1 -0.2 1.6
Supplements: Vitamin C 1.9 2.3 6.1 -1.5 -1.5 -1.4 -1.6 -1.3 -1.6 -1.6 -0.9 -1.9 -1.4 -1.7 -1.5 -1.6 -1.5 -1.5 -1.1 -2.5 1.8 -1.4 -1.1 -0.6 -1.0 -1.9 -1.1
Knee pain experienced in last month 1.2 1.9 6.5 -0.8 -1.0 -1.0 -2.6 -1.0 -1.0 -0.9 0.5 -1.3 -0.9 -1.3 -0.9 -1.4 -1.7 -0.9 -2.2 -1.9 0.8 -2.4 -1.2 -2.0 -1.5 -0.6 -0.4
Hypertension (Self-reported) 0.2 0.5 5.0 -0.2 -0.5 -0.3 0.2 -0.5 -0.1 0.3 -1.2 0.1 -0.2 -0.0 0.7 -0.3 0.3 -0.2 0.7 0.1 -0.2 1.0 -0.5 1.6 0.1 -0.6 2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.2 -0.2 -0.6 -0.3 0.4 -0.5 -0.7 -0.1 -0.2 -0.5 -0.2 -0.5 0.5 -0.6 -0.8 -0.2 -0.7 -0.6 0.5 -1.1 0.2 0.3 -1.1 -0.7 1.1
Illnesses of father: Heart disease 1.0 1.4 2.7 1.6 1.6 1.4 0.6 1.5 1.6 1.1 0.6 1.5 1.5 1.2 1.5 1.3 1.3 1.3 0.1 1.5 -1.4 0.3 -0.0 -0.1 0.8 0.2 1.6
Illnesses of siblings: Diabetes 1.1 1.3 2.7 -1.1 -1.4 -1.0 -1.2 -1.2 -1.4 -1.5 0.1 -0.8 -0.9 -1.5 -1.0 -1.4 -1.3 -0.9 -0.7 -1.5 1.3 -0.8 -1.6 -0.8 -1.2 -1.1 -1.0
Smoking status: Previous 0.5 0.8 3.4 0.6 0.5 0.9 0.8 0.6 0.3 0.7 1.1 1.0 0.9 1.0 0.3 0.8 0.9 1.0 1.2 0.6 -0.5 1.0 -1.2 1.2 0.3 0.7 1.8
Forced expiratory volume in 1-second (FEV1), predicted 0.7 1.5 4.6 -1.2 -1.4 -0.7 -1.4 -0.9 -1.5 -1.5 0.3 -0.4 -1.0 -0.6 -0.5 -1.4 -1.4 -0.6 -1.7 -1.5 1.3 -1.5 -0.1 -1.9 -2.1 -1.3 -0.7
Whole body fat-free mass 0.1 0.4 2.1 -0.2 -0.3 -0.3 0.1 -0.1 -0.1 -0.7 0.8 -0.9 -0.2 -0.6 0.2 -0.3 -0.3 -0.4 -0.4 -0.5 -0.4 -0.9 -1.4 -0.6 -1.5 -0.3 0.2
Leg fat-free mass (right) 0.0 0.2 1.8 0.2 0.0 -0.2 0.3 0.2 0.2 -0.2 1.1 -0.7 0.0 -0.1 0.3 -0.0 -0.3 -0.2 0.2 -0.1 -0.7 -0.8 0.1 -0.1 -1.3 -0.3 0.5
Arm fat percentage (left) 0.2 0.6 4.6 0.5 0.2 -0.1 1.3 0.1 0.4 1.4 2.1 0.0 0.1 1.1 0.6 0.1 -0.3 -0.0 0.7 0.4 -0.4 -0.3 0.1 0.9 -0.7 -0.8 1.5
Average weekly red wine intake 0.8 1.2 2.5 1.4 1.5 0.9 -0.5 1.3 1.0 1.4 1.4 0.6 1.5 1.0 1.6 1.0 1.0 0.9 0.2 1.0 -1.4 -0.1 0.5 0.4 0.9 0.5 1.6
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.2 -0.0 -0.6 0.2 -0.2 -0.1 -0.1 0.1 -0.0 1.0 0.0 0.4 0.1 -0.6 -0.5 0.3 0.1 -0.8 0.6 -1.0 -0.6 -0.9 -1.1 -0.4 -0.1
Mood swings 0.6 1.0 3.0 -1.6 -1.5 -1.0 0.8 -1.5 -1.4 -0.2 -0.9 -0.2 -1.6 -0.4 -1.1 -1.0 -1.0 -1.0 0.1 -1.4 1.7 0.3 0.5 -0.8 -0.3 -0.8 0.2
Loneliness, isolation 2.6 3.6 8.9 -2.6 -2.2 -1.8 -1.8 -2.6 -2.2 -1.5 -2.7 -1.2 -2.9 -1.6 -2.7 -1.8 -1.5 -1.7 -0.7 -2.1 3.0 1.4 -0.2 -1.3 -0.5 -1.6 -0.7
Long-standing illness, disability or infirmity 0.3 0.4 3.4 0.3 0.4 0.4 0.7 0.1 0.2 1.2 0.3 0.7 0.1 0.7 0.1 0.5 0.3 0.4 0.7 -0.1 0.3 0.7 0.8 0.9 0.5 -0.4 1.9
Ever had bowel cancer screening 0.5 0.6 3.5 -0.9 -0.3 0.0 -1.1 -0.2 -0.7 -0.5 -0.3 -1.1 -0.2 -0.8 -0.6 -0.1 0.0 0.0 -1.5 -1.2 0.9 -0.4 -1.9 -0.7 -0.3 1.1 -0.5
Diabetes diagnosed by doctor 0.4 0.7 6.7 -0.1 -0.0 -0.7 0.2 -0.8 -0.2 0.5 -0.5 -0.2 -0.8 -0.2 -0.7 0.0 0.3 -0.6 1.5 0.2 0.4 2.6 0.4 0.8 1.4 -0.2 1.2
Ever had stillbirth, spontaneous miscarriage or termination 2.6 2.7 9.1 2.2 1.9 1.4 1.4 1.8 2.1 1.1 2.4 1.4 1.9 1.8 1.7 1.5 1.1 1.4 0.7 2.3 -3.0 -0.2 1.4 -0.3 1.1 1.5 0.8
Friendships satisfaction 0.8 1.0 2.7 -1.5 -0.9 -0.6 -0.3 -0.7 -1.3 -0.8 -1.6 -1.1 -0.9 -0.9 -0.7 -0.6 -0.6 -0.7 -1.2 -1.3 1.2 -0.5 -1.3 -1.3 -0.8 -1.0 -0.7
Qualifications: nursing, teaching 1.5 2.4 5.4 1.9 1.8 1.7 0.7 1.9 1.5 2.3 2.2 1.5 1.9 1.7 1.4 1.7 1.6 1.7 0.8 1.5 -1.8 0.0 1.5 1.0 0.6 0.7 1.5
Commuting to job workplace: Walk 0.2 0.2 1.7 0.2 0.0 0.5 0.6 0.2 -0.1 0.4 -0.5 0.7 0.3 0.1 0.1 0.2 0.3 0.5 0.1 -0.2 0.3 0.2 -0.7 0.6 0.5 1.3 -0.1
Eye problems/disorders: Cataract 0.3 0.3 2.3 -0.0 0.3 -0.2 0.1 -0.2 -0.2 0.1 -0.1 -0.1 -0.0 -0.4 0.0 0.1 0.7 -0.1 0.5 0.1 -0.2 1.3 -0.2 1.0 1.1 1.5 0.2
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 0.7 0.1 -0.1 -0.5 -0.6 -0.2 -0.2 -0.7 -0.2 -0.2 -0.1 -0.0 -0.1 -0.3 -0.3 -0.6 -0.7 0.3 -0.9 -0.0 -0.4 -0.3 -0.3 0.2 -0.5
Medication for cholesterol 1.7 2.7 8.1 -1.3 -1.1 -1.7 -2.8 -1.0 -1.4 -2.0 -0.5 -2.1 -1.1 -1.8 -1.9 -1.4 -1.7 -1.7 -2.1 -0.9 0.5 -1.2 0.0 -1.9 -2.0 -1.1 -2.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 3.8 -0.7 -1.0 -0.3 0.2 -0.9 -0.8 -0.4 -1.0 -0.1 -0.8 -0.4 0.1 -0.6 -0.6 -0.1 -0.1 -0.9 1.9 0.5 -1.4 0.1 -0.5 -0.4 0.6
Back pain experienced in last month 0.4 0.6 3.6 0.9 0.1 0.2 1.2 -0.1 0.6 1.1 1.1 0.9 -0.1 0.8 0.8 0.1 -0.2 0.3 0.5 0.3 -0.2 -0.3 -1.4 -1.9 0.5 -0.2 0.4
Mineral and other dietary supplements 0.7 0.9 3.1 0.7 1.1 0.6 0.3 0.6 0.6 0.7 0.4 0.6 0.6 0.3 1.0 1.0 1.1 0.6 1.0 1.6 -1.0 1.6 1.4 0.6 1.8 0.9 0.4
Breast cancer (self-reported) 0.8 0.9 5.5 -1.1 -0.6 -1.1 -0.9 -1.1 -0.7 -1.0 -0.7 -0.9 -1.0 -0.7 -2.4 -0.9 -0.8 -1.2 0.3 -0.9 1.1 0.2 0.4 -0.0 0.1 0.6 -1.5
Asthma (self-reported) 0.1 0.2 1.3 0.3 0.4 0.1 1.0 0.3 0.6 0.5 0.0 -0.7 0.6 0.4 0.4 0.2 -0.0 0.1 -0.6 -0.2 -0.5 -0.3 -1.1 0.0 -0.2 0.5 -0.4
Osteoporosis (self-reported) 0.4 0.6 2.0 -0.6 -0.6 -0.9 -0.4 -0.5 -1.0 -0.7 -0.4 -0.3 -0.6 -0.3 -1.1 -0.8 -1.0 -0.9 -0.4 -0.1 -0.5 -0.7 0.3 -1.4 -0.7 -1.0 -1.0
Osteoarthritis (self-reported) 0.2 0.3 1.3 -0.1 0.2 -0.3 -1.2 -0.0 -0.1 -0.6 0.2 -0.8 0.1 -0.7 -0.2 -0.3 -0.1 -0.4 -1.0 -0.5 -0.7 -0.6 -0.1 -0.9 -0.6 0.0 -0.3
Medication: Aspirin 0.5 0.7 2.5 0.5 0.8 1.0 0.9 0.6 0.6 1.4 0.6 0.8 0.6 1.1 0.7 1.1 1.0 1.0 0.6 0.5 -0.3 1.1 -0.1 0.1 0.8 0.3 1.6
Medication: Gliclazide 0.4 0.5 2.8 0.5 0.6 -0.0 -0.1 -0.1 0.3 -0.5 -0.7 -0.1 -0.0 -0.6 0.2 0.5 0.7 -0.0 0.2 1.1 -1.2 1.7 -0.4 1.2 0.8 0.5 1.0
Illnesses of father: None of the above (group 1) 0.4 0.5 2.7 -0.8 -0.4 -0.8 -0.3 -0.7 -0.7 -0.3 -0.7 -0.7 -0.9 -0.5 -0.6 -0.5 -0.1 -0.7 0.7 -0.0 0.4 1.6 -0.4 1.0 0.3 1.2 -0.1
Smoking status: Current 0.2 0.3 1.2 -0.1 -0.3 -0.1 0.9 -0.3 0.0 0.1 -1.1 0.7 -0.4 0.3 0.4 0.0 0.2 -0.1 0.7 0.1 0.1 1.1 0.6 0.8 0.9 0.1 0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.6 5.8 1.8 1.5 1.3 1.3 1.2 1.7 2.4 1.1 2.1 1.2 2.3 1.2 1.6 1.2 1.2 1.5 1.8 -1.1 1.3 2.0 -0.0 1.9 1.8 2.0
Whole body water mass 0.1 0.4 2.2 -0.2 -0.3 -0.3 0.1 -0.0 -0.1 -0.7 0.8 -1.0 -0.1 -0.5 0.1 -0.3 -0.4 -0.4 -0.4 -0.4 -0.5 -1.0 -1.2 -0.7 -1.5 -0.3 0.1
Leg predicted mass (right) 0.0 0.2 1.6 0.2 0.0 -0.2 0.3 0.2 0.2 -0.2 1.1 -0.6 0.0 -0.0 0.3 -0.0 -0.3 -0.2 0.3 -0.0 -0.6 -0.7 0.0 -0.0 -1.3 -0.3 0.5
Arm fat mass (left) 0.1 0.6 4.8 0.5 0.3 0.1 1.2 0.3 0.5 1.2 2.2 -0.0 0.2 1.0 0.8 0.3 0.0 0.1 0.7 0.3 -0.6 -0.3 -0.1 0.6 -0.6 -0.4 1.4
Number of self-reported non-cancer illnesses 0.2 0.4 3.8 0.4 0.0 0.6 0.6 0.3 0.3 0.7 -0.2 0.3 0.4 0.2 0.9 0.2 0.2 0.6 -0.1 -0.6 -0.3 -0.6 -1.1 -0.2 -0.2 -0.4 2.0
Average weekly champagne plus white wine intake 0.6 0.8 1.9 0.5 0.7 0.9 1.2 0.9 0.6 0.9 0.7 1.2 0.7 1.2 1.2 0.9 1.0 1.0 0.3 0.7 -0.5 0.5 0.7 1.3 0.5 0.8 1.4
Miserableness 0.4 0.7 2.6 -1.2 -1.4 -0.4 1.0 -1.2 -0.9 0.1 -0.2 0.4 -1.3 0.2 -1.1 -0.6 -0.6 -0.3 0.8 -0.8 1.6 0.7 1.0 -0.3 -0.0 -1.1 0.6
Guilty feelings 0.3 0.5 1.3 -0.9 -0.6 -0.9 -0.9 -1.0 -0.6 -0.7 -1.1 -1.0 -0.9 -0.6 -1.0 -0.4 -0.4 -0.9 0.2 -0.3 0.4 1.0 0.4 -0.2 0.4 -0.3 -0.3
Wears glasses or contact lenses 0.3 0.3 1.6 0.6 0.7 0.4 -0.2 0.4 0.3 0.3 1.3 0.2 0.5 0.3 0.3 0.4 0.4 0.3 -0.7 0.6 -1.1 -0.4 -1.0 -0.1 -0.5 0.6 -0.0
Ever taken oral contraceptive pill 1.6 1.8 3.5 1.7 1.3 1.3 1.9 1.4 1.7 1.6 0.9 1.9 1.6 1.8 1.5 1.4 1.2 1.3 0.7 1.7 -1.7 0.5 -0.2 0.8 1.1 0.3 1.0
Hearing aid user 0.4 0.4 2.9 0.7 0.6 0.5 0.5 0.3 0.8 0.4 1.7 0.4 0.3 0.4 0.1 0.6 0.7 0.5 0.6 0.8 -0.4 0.8 -0.1 -0.1 0.8 0.4 0.7
Mother’s age at death 0.9 1.1 3.0 1.1 1.2 0.6 0.5 1.1 1.0 0.9 1.7 0.4 1.0 1.1 1.3 1.0 1.0 0.5 1.1 1.4 -1.5 0.2 0.9 0.9 1.0 0.5 1.1
Financial situation satisfaction 2.1 2.6 5.5 -1.6 -2.3 -1.8 -0.5 -2.1 -2.0 -1.4 -0.5 -1.3 -2.3 -1.3 -1.3 -2.0 -1.9 -1.7 -0.6 -1.6 2.1 -0.6 -0.4 -1.2 -1.8 -2.3 -0.5
Tinnitus: Yes, now most or all of the time 0.1 0.1 0.7 0.3 0.3 -0.1 -0.6 -0.1 0.1 0.1 0.7 0.2 0.0 0.3 0.0 -0.0 0.1 -0.0 -0.3 -0.0 -0.1 -0.3 -0.9 0.2 -0.0 0.5 0.6
Commuting to job workplace: Public transport 0.2 0.3 1.2 -0.1 0.3 0.7 -0.6 0.4 -0.4 -0.5 -0.1 0.3 0.5 -0.3 0.5 0.4 0.3 0.6 -1.0 -0.5 -0.2 -1.1 -0.1 0.4 -0.6 1.0 0.1
Eye problems/disorders: Glaucoma 0.6 0.8 3.8 0.6 0.4 0.7 2.0 0.6 0.8 0.8 0.2 0.7 0.7 0.6 1.0 0.7 1.0 0.7 1.0 1.2 -1.0 1.3 1.0 0.8 0.9 0.5 0.3
Medication: Blood pressure 0.4 0.7 4.6 0.4 0.1 0.2 1.1 -0.1 0.6 0.9 -0.4 0.9 -0.0 0.6 0.7 0.3 0.5 0.1 1.5 0.6 -0.2 1.1 0.0 1.4 1.2 0.2 2.1
Pain type(s) experienced in last month: Hip pain 0.3 0.4 1.5 0.7 0.6 0.4 0.3 0.7 0.9 0.5 1.2 0.3 0.5 0.6 1.2 0.2 0.0 0.4 -0.2 0.2 -0.2 -1.1 -0.1 -0.2 -0.5 0.1 0.6
Supplements: Fish oil (including cod liver oil) 1.7 2.2 5.1 -1.5 -2.1 -1.2 -0.4 -1.6 -1.4 -1.2 -1.3 -1.0 -1.6 -0.9 -1.3 -1.7 -1.6 -1.1 -0.9 -2.1 2.1 -1.2 -2.3 -0.1 -2.0 -1.7 0.4
High cholesterol (Self-reported) 0.3 0.4 1.1 0.4 0.6 0.9 1.1 0.8 0.7 0.8 0.6 0.5 0.9 0.9 0.6 0.8 0.5 0.9 0.1 0.4 -0.8 -0.3 -0.4 0.7 0.1 0.2 0.7
Medication: Bendroflumethiazide 0.4 0.6 2.4 0.5 0.2 -0.4 1.1 -0.0 0.6 0.6 -1.0 0.2 -0.0 0.2 0.6 0.1 0.7 -0.5 1.4 0.9 -0.8 0.9 0.7 1.6 1.1 0.2 1.4
Medication: Paracetamol 0.3 0.4 1.0 -0.8 -1.0 -0.8 0.4 -0.8 -0.6 0.1 -0.8 -0.1 -0.8 0.0 -0.4 -0.8 -1.0 -0.8 0.4 -0.4 0.5 -0.1 -0.1 -0.2 -0.8 -1.0 0.2
Medication: Lisinopril 0.1 0.2 1.0 0.5 0.1 -0.4 0.0 -0.5 0.5 0.1 0.6 0.1 -0.4 -0.0 0.3 -0.3 0.2 -0.3 0.7 0.6 -0.3 1.0 0.0 -0.2 0.5 -0.6 -0.2
Medication: Atorvastatin 1.3 1.6 6.0 0.9 0.8 0.9 2.4 0.6 1.1 1.7 -0.3 1.2 0.9 0.8 1.7 1.0 1.5 0.9 1.9 0.7 -0.5 1.4 -1.3 2.0 1.5 0.4 1.3
Illnesses of father: High blood pressure 0.5 0.6 5.0 -0.7 -0.4 0.2 0.8 0.2 -0.4 -0.5 -0.2 -0.0 0.2 -0.0 0.2 -0.4 -0.7 0.1 -1.6 -0.8 0.5 -2.2 -0.7 -0.2 -1.5 -1.2 -0.2
Alcohol drinker status: Never 0.3 0.4 2.6 -0.6 -0.2 -0.4 -0.4 -0.5 -0.4 -0.5 -1.6 -1.0 -0.4 -0.8 0.2 -0.3 -0.2 -0.4 -0.6 -0.3 0.3 0.2 -1.0 0.8 0.1 -0.1 -0.0
Ever smoked 0.3 0.5 2.0 -0.4 -0.7 -0.3 0.0 -0.8 -0.8 0.1 -0.0 0.4 -0.6 0.1 -0.7 -0.2 0.2 -0.2 1.4 -0.5 0.9 1.4 1.3 0.1 0.8 -0.5 0.4
Basal metabolic rate 0.1 0.3 2.0 -0.1 -0.3 -0.3 0.2 -0.0 -0.1 -0.4 1.1 -0.8 -0.2 -0.3 0.3 -0.3 -0.4 -0.3 -0.2 -0.5 -0.3 -0.9 -1.1 -0.5 -1.4 -0.4 0.3
Leg fat percentage (left) 0.3 0.9 4.3 0.7 0.4 0.4 2.0 0.1 0.8 1.8 2.1 0.6 0.2 1.4 0.8 0.5 0.4 0.5 1.2 0.6 -0.1 0.6 -1.0 0.9 0.2 -0.5 1.2
Arm fat-free mass (left) 0.0 0.2 1.6 -0.0 -0.0 -0.0 0.3 0.1 0.1 -0.2 0.9 -0.6 -0.0 -0.1 0.3 -0.0 0.1 -0.1 -0.1 -0.3 -0.5 -0.5 -1.3 -0.5 -0.9 0.0 0.3
Number of operations (self-reported) 0.4 0.6 2.9 -0.0 0.3 -0.8 -1.7 -0.2 -0.2 -0.6 -0.1 -1.6 -0.1 -1.0 0.3 -0.5 -0.1 -0.8 -1.0 -0.5 -0.1 -0.4 -1.7 -0.6 0.4 0.8 0.1
Average weekly beer plus cider intake 0.3 0.4 2.0 -0.4 -0.9 -0.5 -0.2 -0.7 -0.3 -0.1 0.5 0.3 -0.9 0.0 -1.1 -0.8 -0.5 -0.5 0.7 -0.4 1.0 0.5 -0.3 -1.4 0.0 0.0 -0.3
Irritability 0.3 0.5 3.1 -0.6 -0.6 -0.3 1.0 -0.8 -0.5 0.4 -0.1 0.2 -0.8 0.4 -0.1 -0.4 0.2 -0.3 1.1 -0.8 1.8 1.1 1.4 0.0 0.9 -0.0 0.3
Risk taking 0.5 0.7 2.5 -0.5 -1.4 -0.8 0.7 -1.3 -0.2 0.1 -0.8 0.3 -1.3 0.1 -0.1 -0.7 -0.6 -0.7 1.0 -0.2 1.4 1.3 0.3 -0.3 0.1 -1.6 0.4
Ever had prostate specific antigen (PSA) test 0.5 0.5 3.7 0.0 1.1 0.2 -0.8 0.6 0.4 -0.5 0.5 -0.7 0.3 -0.6 -0.1 0.8 1.0 0.0 -0.9 0.4 -1.1 0.7 -1.9 -0.5 0.6 0.9 -0.1
Fractured/broken bones in last 5 years 1.0 1.3 2.8 -0.7 -1.5 -1.3 -1.1 -1.0 -1.0 -1.1 0.3 -1.4 -1.1 -0.6 -0.8 -1.5 -1.5 -1.2 -1.3 -1.0 1.2 -0.9 -1.4 -1.4 -1.1 -1.7 -0.9
Age started oral contraceptive pill 4.5 5.6 12.6 -2.2 -2.2 -2.7 -3.0 -2.4 -1.7 -2.7 -1.8 -3.0 -2.4 -2.6 -2.6 -2.5 -2.4 -2.8 -2.1 -2.1 1.5 -1.5 -3.5 -0.9 -1.9 -2.5 -2.2
Diastolic blood pressure, automated reading 0.1 0.4 1.3 -0.6 -0.7 -0.7 -0.8 -0.8 -0.7 -0.2 0.4 -0.5 -0.8 -0.4 -0.0 -0.9 -0.6 -0.6 0.3 -1.0 1.1 -0.1 -0.4 -0.7 -0.3 -0.8 -0.4
Ever depressed for a whole week 0.8 1.0 4.1 0.3 0.3 1.4 1.2 0.4 0.0 1.5 1.1 1.9 0.4 1.6 1.3 0.7 0.7 1.5 -0.0 -0.0 0.6 0.1 -0.9 0.4 0.4 -0.4 2.0
Unable to work because of sickness or disability 1.3 1.7 4.9 -1.2 -1.9 -1.7 -0.0 -2.2 -1.3 -1.0 -1.1 -0.5 -2.1 -1.0 -1.8 -1.6 -1.2 -1.4 0.9 -0.8 1.8 1.3 -0.4 0.6 -0.3 -1.1 0.0
Commuting to job workplace: Cycle 0.5 0.6 2.0 0.3 0.5 0.9 -0.8 0.6 0.3 0.6 -0.6 0.7 0.5 0.2 0.4 1.0 0.7 1.0 0.4 0.3 0.2 1.4 -0.3 1.2 1.1 1.4 1.4
Myopia 0.8 1.1 2.5 1.4 1.3 1.3 1.6 1.3 0.9 1.3 1.1 1.2 1.2 1.4 0.9 1.2 0.8 1.3 0.2 1.1 -0.3 0.0 0.9 0.7 0.0 0.5 0.9
Vascular/heart problems diagnosed by doctor 0.1 0.4 2.9 0.3 0.2 0.1 -0.3 0.3 0.1 -0.3 1.4 0.3 0.2 0.3 -0.4 0.0 -0.5 0.1 -0.4 0.3 0.3 -0.8 0.7 -1.1 -0.4 0.6 -1.7
Cholesterol lowering medication 1.4 2.1 8.6 1.0 0.7 1.2 2.9 0.8 1.0 1.7 -0.1 1.9 0.8 1.4 1.4 1.1 1.2 1.2 2.1 1.0 -0.2 1.4 -0.1 1.8 2.0 0.2 2.5
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 2.2 0.5 0.6 0.6 1.3 0.3 0.8 0.5 -0.4 0.7 0.3 0.2 1.0 0.7 0.5 0.7 1.0 1.0 -0.1 0.9 -0.3 1.5 1.0 0.5 1.1
Pain experienced in last month 0.1 0.2 1.4 0.1 0.5 0.2 0.4 0.7 -0.0 -0.2 -0.1 -0.4 0.6 -0.0 0.3 0.4 0.8 0.1 0.1 0.3 -0.4 0.3 0.3 1.2 -0.1 0.7 -0.4
Supplements: Calcium 0.4 0.4 1.4 -0.8 -1.2 -0.3 -0.1 -0.7 -1.1 -0.5 -1.1 0.0 -0.6 -0.3 -1.0 -0.8 -0.5 -0.1 0.3 -1.0 0.9 -0.2 0.4 -0.4 -0.6 -0.4 -0.3
Basal cell carcinoma (self-reported) 0.3 0.3 1.8 -0.1 -0.5 0.3 1.1 -0.3 -0.8 0.4 -0.1 0.5 -0.2 0.2 -0.2 -0.2 0.2 0.4 1.1 -1.1 1.3 0.0 -0.2 0.0 0.2 0.4 0.0
Heart attack/myocardial infarction (self-reported) 2.0 2.6 5.0 1.5 1.5 1.7 2.2 1.5 1.8 2.1 1.0 2.1 1.6 2.0 1.6 1.6 1.7 1.7 1.8 1.5 -1.1 1.1 -1.1 1.6 1.6 1.1 1.6
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 1.7 0.4 0.1 0.8 1.3 0.6 0.4 0.5 -0.3 0.9 0.5 1.0 0.3 0.6 0.4 0.7 1.2 0.4 0.2 0.2 1.1 0.4 0.5 0.0 0.2
Heart disease (siblings) 0.3 0.3 0.9 0.3 0.7 0.8 0.4 0.7 0.5 0.5 0.8 -0.2 0.7 0.1 0.4 0.9 0.9 0.7 0.2 0.1 -0.4 0.4 -0.4 0.3 0.9 0.8 0.2
Alcohol drinker status: Previous 0.6 0.7 2.2 -0.9 -0.9 -1.0 -0.3 -1.3 -0.7 -0.8 -1.5 -0.4 -1.2 -0.9 -0.1 -0.9 -0.4 -0.9 0.1 -0.8 1.5 0.9 -0.6 0.6 0.6 -0.1 -0.4
Pack years of smoking 0.2 0.4 2.9 -0.1 0.1 0.3 0.5 -0.1 0.2 -0.0 -0.4 0.3 -0.1 -0.1 -0.3 0.4 0.5 0.4 0.5 -0.2 0.1 0.8 -0.1 1.7 0.6 1.3 1.1
Impedance of whole body 0.4 2.2 10.9 -1.1 -0.8 -1.6 -3.3 -1.3 -1.2 -1.5 -0.7 -1.3 -1.2 -1.8 -1.5 -1.6 -1.2 -1.6 -1.7 -1.4 1.4 -0.8 -1.4 -0.8 -0.3 -0.8 -2.2
Leg fat mass (left) 0.2 0.9 4.9 0.9 0.6 0.4 1.7 0.4 1.0 1.5 2.2 0.4 0.4 1.3 1.1 0.6 0.4 0.5 1.0 0.7 -0.6 0.3 -0.7 0.7 -0.0 -0.3 1.4
Arm predicted mass (left) 0.0 0.2 0.9 0.1 0.1 0.2 0.4 0.3 0.2 -0.1 0.9 -0.5 0.2 -0.0 0.3 0.1 0.2 0.1 -0.0 -0.4 -0.5 -0.7 -0.9 -0.4 -0.9 0.2 0.3