Best TWAS P=5.62e-08 · Best GWAS P=7.74e-10 conditioned to 2.23e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | MED19 | 0.14 | 0.07 | lasso | 4 | 0.11 | 5.9e-08 | -5.5 | 5.3 | 1.0e-07 | -0.28 | 0.02 | 0.98 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | AP000662.4 | 0.05 | 0.01 | enet | 17 | 0.02 | 3.8e-04 | -5.6 | 5.4 | 5.6e-08 | -0.30 | 0.02 | 0.97 | TRUE |