Best TWAS P=6.2e-08 · Best GWAS P=2.51e-07 conditioned to 0.0929
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CTD-3074O7.5 | 0.11 | 0.03 | lasso | 4 | 0.02 | 4.2e-03 | -4.8 | -5.2 | 2.2e-07 | -0.25 | 0.04 | 0.83 | TRUE |
| 2 | GTEx | Artery Aorta | PACS1 | 0.14 | 0.03 | enet | 20 | 0.10 | 6.3e-06 | 4.2 | -5.1 | 2.7e-07 | -0.80 | 0.11 | 0.77 | FALSE |
| 3 | GTEx | Artery Tibial | PACS1 | 0.06 | 0.05 | enet | 5 | 0.03 | 9.2e-04 | 5.2 | -5.4 | 6.2e-08 | -0.91 | 0.01 | 0.96 | TRUE |
| 4 | GTEx | Breast Mammary Tissue | RP11-755F10.1 | 0.20 | 0.14 | lasso | 3 | 0.11 | 2.2e-06 | 5.2 | 5.1 | 2.8e-07 | 0.99 | 0.01 | 0.99 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | YIF1A | 0.03 | 0.01 | blup | 300 | 0.01 | 1.0e-02 | 4.7 | -5.3 | 1.5e-07 | -0.76 | 0.03 | 0.80 | FALSE |