Best TWAS P=2.83e-16 · Best GWAS P=3.47e-17 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | FBXL3 | 0.18 | 0.07 | enet | 15 | 0.07 | 4.5e-06 | -7.8 | 6.3 | 3.9e-10 | -0.71 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Artery Tibial | CLN5 | 0.07 | 0.02 | lasso | 3 | 0.04 | 5.9e-04 | -8.4 | 8.2 | 2.8e-16 | -0.96 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CLN5 | 0.09 | 0.03 | blup | 46 | 0.08 | 1.6e-09 | -5.6 | 6.3 | 2.3e-10 | -0.67 | 0.66 | 0.33 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CLN5 | 0.04 | 0.02 | blup | 46 | 0.03 | 1.0e-03 | -3.7 | 6.0 | 1.9e-09 | -0.68 | 0.09 | 0.46 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | CLN5 | 0.11 | 0.02 | blup | 46 | 0.06 | 3.2e-06 | -5.5 | 5.8 | 5.6e-09 | -0.54 | 0.16 | 0.42 | FALSE |