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chr13:76,867,667-78,295,338
Best TWAS P=2.83e-16 · Best GWAS P=3.47e-17 conditioned to 1
76.8M
77M
77.2M
77.4M
77.6M
77.8M
78M
78.2M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
CLN5
0.07
0.02
lasso
3
0.04
5.9e-04
-8.4
8.2
2.8e-16
-0.96
0.00
1.00
TRUE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
CLN5
0.09
0.03
blup
46
0.08
1.6e-09
-5.6
6.3
2.3e-10
-0.67
0.66
0.33
FALSE
1
GTEx
Artery Tibial
FBXL3
0.18
0.07
enet
15
0.07
4.5e-06
-7.8
6.3
3.9e-10
-0.71
0.02
0.98
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
CLN5
0.04
0.02
blup
46
0.03
1.0e-03
-3.7
6.0
1.9e-09
-0.68
0.09
0.46
FALSE
5
The Cancer Genome Atlas
Thyroid Carcinoma
CLN5
0.11
0.02
blup
46
0.06
3.2e-06
-5.5
5.8
5.6e-09
-0.54
0.16
0.42
FALSE