Best TWAS P=2.85e-08 · Best GWAS P=3.4e-07 conditioned to 0.0512
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | COQ5 | 0.30 | 0.20 | lasso | 8 | 0.22 | 4.9e-15 | 3.9 | 5.1 | 2.8e-07 | -0.52 | 0.42 | 0.38 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | COQ5 | 0.05 | 0.01 | blup | 56 | 0.03 | 9.0e-04 | 3.8 | 5.4 | 6.8e-08 | -0.69 | 0.06 | 0.39 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | COQ5 | 0.15 | 0.14 | blup | 56 | 0.15 | 6.3e-17 | 3.9 | 5.6 | 2.9e-08 | -0.65 | 0.43 | 0.37 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | TRIAP1 | 0.04 | 0.02 | blup | 44 | 0.02 | 1.8e-03 | 3.9 | -5.1 | 3.1e-07 | 0.59 | 0.04 | 0.32 | FALSE |