Best TWAS P=1.08e-07 · Best GWAS P=5.63e-08 conditioned to 0.0676
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 0.00005 | -5.4 | -5.1 | 2.6e-07 | 0.96 | 0.02 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CADM2 | 0.14 | 0.05 | blup | 339 | 0.09 | 0.00027 | -4.8 | -5.3 | 1.1e-07 | 0.83 | 0.04 | 0.82 | TRUE |