Best TWAS P=6.95e-08 · Best GWAS P=6.56e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | NEK4 | 0.10 | 0.09 | lasso | 3 | 0.08 | 5.0e-05 | -5.1 | 5.1 | 3.0e-07 | -0.87 | 0.09 | 0.90 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | NT5DC2 | 0.23 | 0.10 | lasso | 4 | 0.09 | 8.3e-06 | -5.4 | 5.4 | 8.0e-08 | -1.00 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | NT5DC2 | 0.21 | 0.19 | enet | 12 | 0.18 | 2.0e-14 | -5.4 | 5.4 | 6.9e-08 | -0.99 | 0.02 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | NEK4 | 0.07 | 0.12 | blup | 69 | 0.12 | 6.3e-12 | -5.1 | 5.1 | 2.7e-07 | -0.90 | 0.03 | 0.96 | FALSE |