Best TWAS P=1.84e-10 · Best GWAS P=7.43e-13 conditioned to 1.42e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PAX6 | 0.11 | 0.06 | enet | 3 | 0.05 | 4.2e-06 | 5.9 | 5.2 | 2.3e-07 | 0.40 | 0.62 | 0.14 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | PAX6 | 0.11 | 0.11 | lasso | 3 | 0.09 | 2.2e-09 | 5.9 | 6.4 | 1.8e-10 | 0.56 | 0.84 | 0.16 | TRUE |