Best TWAS P=7.19e-09 · Best GWAS P=3.79e-10 conditioned to 0.0133
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | IGSF9B | 0.27 | 0.01 | enet | 7 | -0.01 | 5.4e-01 | -5.5 | -5.8 | 7.2e-09 | 0.88 | 0.02 | 0.82 | TRUE |
| 2 | GTEx | Testis | IGSF9B | 0.19 | 0.09 | lasso | 7 | 0.10 | 3.4e-05 | -4.8 | -5.2 | 2.2e-07 | 0.68 | 0.12 | 0.77 | FALSE |
| 3 | GTEx | Thyroid | IGSF9B | 0.28 | 0.20 | enet | 9 | 0.22 | 1.2e-16 | -4.7 | -5.4 | 6.5e-08 | 0.68 | 0.82 | 0.18 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | IGSF9B | 0.08 | 0.10 | lasso | 2 | 0.11 | 3.8e-11 | -4.8 | -5.4 | 5.6e-08 | 0.70 | 0.76 | 0.24 | FALSE |