Best TWAS P=5.82e-09 · Best GWAS P=1.04e-09 conditioned to 0.0493
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Spleen | GALNT16 | 0.26 | 0.04 | lasso | 7 | 0.04 | 0.033 | 5.0 | 5.6 | 1.8e-08 | -0.66 | 0.04 | 0.72 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | DCAF5 | 0.04 | 0.01 | blup | 77 | 0.01 | 0.027 | -5.3 | 5.8 | 5.8e-09 | -0.90 | 0.02 | 0.62 | TRUE |