Best TWAS P=1.4e-07 · Best GWAS P=1.3e-06 conditioned to 0.673
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | NCOA6 | 0.11 | 0.10 | lasso | 10 | 0.10 | 4.5e-06 | 4.7 | 5.1 | 2.9e-07 | 0.92 | 0.08 | 0.86 | FALSE |
| 2 | GTEx | Brain Cortex | NCOA6 | 0.14 | 0.03 | enet | 13 | 0.05 | 1.6e-02 | -3.6 | 5.1 | 3.0e-07 | 0.75 | 0.05 | 0.51 | FALSE |
| 3 | GTEx | Brain Nucleus accumbens basal ganglia | NCOA6 | 0.24 | 0.01 | lasso | 12 | 0.08 | 3.2e-03 | -3.6 | 5.1 | 2.7e-07 | 0.65 | 0.06 | 0.67 | FALSE |
| 4 | GTEx | Colon Transverse | NCOA6 | 0.10 | 0.06 | lasso | 8 | 0.04 | 4.1e-03 | 4.8 | 5.2 | 1.7e-07 | 0.96 | 0.03 | 0.90 | FALSE |
| 5 | GTEx | Esophagus Gastroesophageal Junction | NCOA6 | 0.24 | 0.07 | lasso | 4 | 0.08 | 5.9e-04 | 4.8 | 5.3 | 1.4e-07 | 0.88 | 0.04 | 0.87 | TRUE |
| 6 | GTEx | Skin Not Sun Exposed Suprapubic | NCOA6 | 0.13 | 0.03 | enet | 12 | 0.03 | 1.5e-02 | 4.8 | 5.2 | 2.5e-07 | 0.71 | 0.04 | 0.81 | FALSE |