[Hub]/) : Traits : Neuroticism : ← →

chr20:43,958,786-45,456,440

Best TWAS P=6.53e-11 · Best GWAS P=1.28e-09 conditioned to 0.00535

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CD40	0.10	0.01	blup	63	0.09	5.8e-06	-5.0	-6.5	6.5e-11	-0.58	0.16	0.46	TRUE
3	METSIM	Adipose	CD40	0.07	0.04	lasso	4	0.05	3.5e-08	5.3	-6.2	6.0e-10	-0.75	0.04	0.96	FALSE
4	ROSMAP	Brain Pre-frontal Cortex	SLC12A5	0.24	0.24	lasso	6	0.24	5.4e-30	6.1	6.0	2.3e-09	0.98	0.00	1.00	FALSE
6	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CD40	0.04	0.02	enet	10	0.04	2.2e-05	-5.2	-5.8	7.5e-09	-0.57	0.17	0.71	FALSE
1	GTEx	Nerve Tibial	CD40	0.13	0.01	lasso	5	0.02	1.4e-02	5.1	-5.6	2.6e-08	-0.80	0.02	0.94	FALSE
2	GTEx	Skin Sun Exposed Lower leg	CD40	0.13	0.08	lasso	3	0.08	4.1e-07	-5.0	-5.5	3.9e-08	-0.40	0.34	0.64	FALSE
8	The Cancer Genome Atlas	Brain Lower Grade Glioma	CD40	0.08	0.06	blup	63	0.09	4.4e-10	4.5	-5.5	4.2e-08	-0.75	0.00	1.00	FALSE
9	The Cancer Genome Atlas	Thyroid Carcinoma	CD40	0.03	0.00	blup	63	0.01	1.4e-02	-5.0	-5.2	1.9e-07	-0.67	0.04	0.27	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	CD40	0.06	0.05	blup	63	0.06	3.3e-12	5.2	-5.1	2.6e-07	-0.76	0.20	0.79	FALSE