[Hub]/) : Traits : Neuroticism : ← →

chr20:17,776,692-19,441,650

Best TWAS P=3.51e-08 · Best GWAS P=6.21e-08 conditioned to 0.404

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Skin Not Sun Exposed Suprapubic	DTD1	0.14	0.14	lasso	4	0.13	8.9e-08	-5.2	5.5	3.5e-08	-0.92	0.02	0.98	TRUE
8	The Cancer Genome Atlas	Glioblastoma Multiforme	LOC388789	0.25	0.11	lasso	2	0.07	3.4e-03	-5.4	5.5	5.0e-08	-1.00	0.00	0.85	FALSE
3	GTEx	Muscle Skeletal	DTD1	0.08	0.07	lasso	2	0.05	7.1e-06	-5.4	5.4	6.1e-08	-0.97	0.01	0.99	FALSE
2	GTEx	Esophagus Muscularis	RBBP9	0.08	0.03	lasso	2	0.00	2.1e-01	-5.4	5.4	7.7e-08	-0.97	0.02	0.86	FALSE
4	GTEx	Ovary	DTD1	0.27	0.20	lasso	2	0.18	3.3e-05	-5.3	5.3	9.6e-08	-0.88	0.02	0.91	FALSE
7	GTEx	Testis	LINC00493	0.11	0.05	lasso	5	0.03	1.3e-02	-5.4	5.3	1.2e-07	-0.93	0.02	0.94	FALSE
9	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RBBP9	0.10	0.08	lasso	2	0.07	5.9e-04	-5.4	5.2	1.8e-07	-0.95	0.00	0.96	FALSE
1	GTEx	Artery Tibial	DTD1	0.09	0.04	lasso	2	0.03	3.8e-03	-5.1	5.2	2.3e-07	-0.85	0.02	0.97	FALSE
6	GTEx	Skin Sun Exposed Lower leg	DTD1	0.15	0.07	lasso	6	0.10	2.7e-08	-4.6	5.2	2.3e-07	-0.89	0.03	0.97	FALSE