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chr6:110,588,546-112,621,834

Best TWAS P=1.92e-19 · Best GWAS P=2.11e-20 conditioned to 0.008

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Brain Hypothalamus	GTF3C6	0.32	0.04	lasso	4	0.08	6.8e-03	9.21	-9.0	1.9e-19	-0.90	0.02	0.83	TRUE
5	GTEx	Brain Cerebellum	REV3L	0.31	0.04	lasso	11	0.12	2.4e-04	9.13	8.7	3.0e-18	0.84	0.02	0.91	FALSE
9	GTEx	Colon Transverse	RP5-1112D6.4	0.11	0.10	lasso	4	0.06	7.1e-04	7.64	8.1	4.5e-16	0.80	0.35	0.14	FALSE
3	GTEx	Adipose Subcutaneous	RP5-1112D6.4	0.08	0.03	lasso	4	0.03	2.1e-03	6.28	7.2	6.7e-13	0.83	0.04	0.95	FALSE
8	GTEx	Cells Transformed fibroblasts	RP5-1112D6.4	0.15	0.06	lasso	2	0.06	4.0e-05	6.28	6.9	4.2e-12	0.80	0.12	0.83	FALSE
4	GTEx	Artery Aorta	RP5-1112D6.4	0.15	0.01	lasso	7	0.02	3.5e-02	7.66	6.8	8.2e-12	0.72	0.06	0.74	FALSE
11	GTEx	Pituitary	RP5-1112D6.4	0.23	0.16	lasso	4	0.13	4.4e-04	5.29	6.5	6.4e-11	0.78	0.08	0.62	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	REV3L	0.16	0.16	bslmm	468	0.18	1.9e-22	7.66	6.5	7.6e-11	0.72	0.43	0.57	FALSE
1	CommonMind	Brain Pre-frontal Cortex	REV3L	0.15	0.10	lasso	5	0.14	9.8e-17	7.72	6.4	1.3e-10	0.73	0.85	0.15	FALSE
7	GTEx	Breast Mammary Tissue (Female)	C6orf3	0.32	0.06	lasso	6	0.02	6.2e-02	5.72	6.0	1.9e-09	0.40	0.09	0.13	FALSE
2	GTEx	Adipose Subcutaneous	KIAA1919	0.07	0.01	enet	16	0.01	3.6e-02	-4.38	5.8	7.8e-09	0.44	0.29	0.12	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	C6orf3	0.27	0.01	lasso	6	0.05	8.1e-03	-0.77	5.2	1.9e-07	0.35	0.09	0.52	FALSE