[Hub]/) : Traits : Smoking Status : ← →

chr6:110,588,546-112,621,834

Best TWAS P=1.92e-19 · Best GWAS P=2.11e-20 conditioned to 0.008

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex REV3L 0.15 0.10 lasso 5 0.14 9.8e-17 7.72 6.4 1.3e-10 0.73 0.85 0.15 FALSE
2 GTEx Adipose Subcutaneous KIAA1919 0.07 0.01 enet 16 0.01 3.6e-02 -4.38 5.8 7.8e-09 0.44 0.29 0.12 FALSE
3 GTEx Adipose Subcutaneous RP5-1112D6.4 0.08 0.03 lasso 4 0.03 2.1e-03 6.28 7.2 6.7e-13 0.83 0.04 0.95 FALSE
4 GTEx Artery Aorta RP5-1112D6.4 0.15 0.01 lasso 7 0.02 3.5e-02 7.66 6.8 8.2e-12 0.72 0.06 0.74 FALSE
5 GTEx Brain Cerebellum REV3L 0.31 0.04 lasso 11 0.12 2.4e-04 9.13 8.7 3.0e-18 0.84 0.02 0.91 FALSE
6 GTEx Brain Hypothalamus GTF3C6 0.32 0.04 lasso 4 0.08 6.8e-03 9.21 -9.0 1.9e-19 -0.90 0.02 0.83 TRUE
7 GTEx Breast Mammary Tissue (Female) C6orf3 0.32 0.06 lasso 6 0.02 6.2e-02 5.72 6.0 1.9e-09 0.40 0.09 0.13 FALSE
8 GTEx Cells Transformed fibroblasts RP5-1112D6.4 0.15 0.06 lasso 2 0.06 4.0e-05 6.28 6.9 4.2e-12 0.80 0.12 0.83 FALSE
9 GTEx Colon Transverse RP5-1112D6.4 0.11 0.10 lasso 4 0.06 7.1e-04 7.64 8.1 4.5e-16 0.80 0.35 0.14 FALSE
10 GTEx Esophagus Gastroesophageal Junction C6orf3 0.27 0.01 lasso 6 0.05 8.1e-03 -0.77 5.2 1.9e-07 0.35 0.09 0.52 FALSE
11 GTEx Pituitary RP5-1112D6.4 0.23 0.16 lasso 4 0.13 4.4e-04 5.29 6.5 6.4e-11 0.78 0.08 0.62 FALSE
12 ROSMAP Brain Pre-frontal Cortex REV3L 0.16 0.16 bslmm 468 0.18 1.9e-22 7.66 6.5 7.6e-11 0.72 0.43 0.57 FALSE