TWAS
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Traits
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chr7:1,181,139-2,580,275
Best TWAS P=2.57e-09 · Best GWAS P=5.16e-10 conditioned to 0.278
1.2M
1.4M
1.6M
1.8M
2M
2.2M
2.4M
2.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
AC110781.3
0.11
0.06
lasso
5
0.10
1.9e-12
5.7
6.0
2.6e-09
0.83
0.11
0.89
TRUE
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
KIAA1908
0.09
0.02
blup
50
0.06
1.7e-04
4.9
5.2
2.4e-07
0.13
0.01
0.87
TRUE