Best TWAS P=2.57e-09 · Best GWAS P=5.16e-10 conditioned to 0.278
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | AC110781.3 | 0.11 | 0.06 | lasso | 5 | 0.10 | 1.9e-12 | 5.7 | 6.0 | 2.6e-09 | 0.83 | 0.11 | 0.89 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | KIAA1908 | 0.09 | 0.02 | blup | 50 | 0.06 | 1.7e-04 | 4.9 | 5.2 | 2.4e-07 | 0.13 | 0.01 | 0.87 | TRUE |