Best TWAS P=3.8e-09 · Best GWAS P=2.95e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF362 | 0.05 | 0.06 | lasso | 1 | 0.06 | 2.2e-07 | -5.5 | -5.5 | 4.5e-08 | 0.98 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | PHC2 | 0.58 | 0.34 | lasso | 7 | 0.28 | 7.3e-10 | -5.7 | 5.9 | 3.8e-09 | -0.99 | 0.01 | 0.99 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | PHC2 | 0.11 | 0.07 | lasso | 3 | 0.05 | 2.2e-07 | -5.7 | -5.5 | 4.6e-08 | 0.99 | 0.01 | 0.99 | FALSE |