Best TWAS P=8.2e-10 · Best GWAS P=1.36e-13 conditioned to 3.2e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MED8 | 0.04 | 0.00 | blup | 455 | 0.01 | 0.0113 | 7.4 | -5.3 | 9.7e-08 | -0.63 | 0.01 | 0.90 | FALSE |
| 2 | GTEx | Heart Left Ventricle | MED8 | 0.08 | 0.01 | lasso | 3 | 0.01 | 0.1180 | -6.1 | 5.2 | 2.1e-07 | 0.37 | 0.18 | 0.08 | FALSE |
| 3 | GTEx | Muscle Skeletal | ST3GAL3 | 0.10 | 0.01 | enet | 27 | 0.01 | 0.0162 | -6.1 | 6.1 | 8.2e-10 | 0.60 | 0.07 | 0.88 | TRUE |
| 4 | GTEx | Muscle Skeletal | RP11-7O11.3 | 0.05 | 0.02 | lasso | 3 | 0.02 | 0.0072 | 5.1 | -5.4 | 5.9e-08 | -0.67 | 0.12 | 0.25 | FALSE |