Best TWAS P=1.77e-07 · Best GWAS P=2e-15 conditioned to 8.41e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | LIN7C | 0.08 | 0.06 | lasso | 1 | 0.04 | 0.00041 | 5.2 | 5.2 | 1.8e-07 | -0.26 | 0.86 | 0.00 | TRUE |
| 2 | GTEx | Brain Putamen basal ganglia | BDNF-AS | 0.22 | 0.17 | lasso | 4 | 0.13 | 0.00055 | -4.6 | 5.1 | 3.0e-07 | -0.65 | 0.05 | 0.81 | TRUE |
| 3 | NTR | Blood | LIN7C | 0.01 | 0.00 | lasso | 3 | 0.01 | 0.00218 | 5.5 | -5.2 | 2.0e-07 | 0.17 | 0.52 | 0.01 | FALSE |