TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Smoking Status
:
←
→
chr11:26,818,083-28,416,646
Best TWAS P=1.77e-07 · Best GWAS P=2e-15 conditioned to 8.41e-10
26.8M
27M
27.2M
27.4M
27.6M
27.8M
28M
28.2M
28.4M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
LIN7C
0.08
0.06
lasso
1
0.04
0.00041
5.2
5.2
1.8e-07
-0.26
0.86
0.00
TRUE
2
GTEx
Brain Putamen basal ganglia
BDNF-AS
0.22
0.17
lasso
4
0.13
0.00055
-4.6
5.1
3.0e-07
-0.65
0.05
0.81
TRUE
3
NTR
Blood
LIN7C
0.01
0.00
lasso
3
0.01
0.00218
5.5
-5.2
2.0e-07
0.17
0.52
0.01
FALSE