Best TWAS P=1.57e-07 · Best GWAS P=5.97e-07 conditioned to 0.368
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CCDC88B | 0.22 | 0.24 | bslmm | 358 | 0.25 | 5.8e-30 | -4.9 | 5.1 | 2.8e-07 | -0.95 | 0.01 | 0.99 | TRUE |
2 | GTEx | Skin Sun Exposed Lower leg | NRXN2 | 0.11 | 0.05 | enet | 27 | 0.08 | 7.0e-07 | 3.8 | 5.2 | 1.6e-07 | -0.38 | 0.35 | 0.39 | TRUE |