Best TWAS P=1.28e-09 · Best GWAS P=3.13e-10 conditioned to 0.00776
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | KCNJ11 | 0.17 | 0.01 | enet | 24 | 0.06 | 7.7e-03 | 3.3 | -5.7 | 1.5e-08 | 0.64 | 0.06 | 0.69 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | PIK3C2A | 0.10 | 0.08 | lasso | 4 | 0.08 | 1.3e-06 | -6.2 | 6.1 | 1.3e-09 | -0.74 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | OR7E14P | 0.11 | 0.05 | lasso | 6 | 0.08 | 4.3e-07 | -5.6 | 5.2 | 2.6e-07 | -0.69 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | PIK3C2A | 0.05 | 0.01 | blup | 52 | 0.03 | 7.2e-03 | -5.6 | 5.7 | 9.4e-09 | -0.77 | 0.02 | 0.62 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | PIK3C2A | 0.08 | 0.05 | lasso | 3 | 0.05 | 9.6e-06 | -5.6 | 5.5 | 3.1e-08 | -0.81 | 0.02 | 0.98 | FALSE |