TWAS hub - NRXN2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1070	0.0380	6.3e-05	0.055	NA	0.053	NA	0.049	2.7e-05	NA	3.4e-05	NA	7.4e-05
2	GTEx	Artery Tibial	0.1665	0.0469	1.8e-07	0.116	NA	0.094	NA	0.123	2.4e-09	NA	8.4e-08	NA	6.9e-10
3	GTEx	Cells Transformed fibroblasts	0.1490	0.0460	3.9e-06	0.050	NA	0.030	NA	0.062	1.2e-04	NA	2.6e-03	NA	2.0e-05
4	GTEx	Liver	0.3870	0.1050	2.2e-04	0.073	NA	0.139	NA	0.158	4.5e-03	NA	1.1e-04	NA	3.6e-05
5	GTEx	Lung	0.1769	0.0453	2.3e-07	0.128	NA	0.123	NA	0.118	5.0e-10	NA	1.2e-09	NA	2.4e-09
6	GTEx	Nerve Tibial	0.0784	0.0349	3.8e-03	0.051	NA	0.050	NA	0.066	1.6e-04	NA	1.9e-04	NA	2.0e-05
7	GTEx	Skin Not Sun Exposed Suprapubic	0.1000	0.0420	5.3e-03	0.075	NA	0.052	NA	0.049	6.5e-05	NA	7.8e-04	NA	1.0e-03
8	GTEx	Skin Sun Exposed Lower leg	0.1140	0.0360	2.9e-05	0.051	NA	0.076	NA	0.057	4.9e-05	NA	7.0e-07	NA	1.6e-05
9	GTEx	Spleen	0.4650	0.1280	1.5e-03	0.124	NA	0.097	NA	0.104	4.6e-04	NA	1.8e-03	NA	1.3e-03
10	TCGA	Breast Invasive Carcinoma	0.0108	0.0075	6.6e-03	0.016	0.010	0.009	NA	0.014	2.3e-04	2.8e-03	3.8e-03	NA	5.1e-04
11	TCGA	Lung Adenocarcinoma	0.0676	0.0324	1.2e-06	0.058	0.053	0.064	NA	0.052	2.6e-07	7.2e-07	6.2e-08	NA	1.0e-06
12	TCGA	Prostate Adenocarcinoma	0.0271	0.0186	3.1e-03	0.032	0.023	0.027	NA	0.026	2.7e-04	1.5e-03	7.2e-04	NA	8.8e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Gout (self-reported)	35.7	48.9	68.7	8.0	7.4	8.3	4.7	6.2	7.5	7.9	7.5	7.7	7.9	2.9	5.9
Medication: Allopurinol	21.8	29.0	42.5	6.0	5.9	6.5	3.6	4.9	5.7	6.1	5.9	5.9	6.0	2.1	4.0
Ever smoked	8.4	14.7	24.5	4.0	4.5	4.4	0.2	3.5	4.2	4.2	5.0	4.1	3.9	2.5	3.1
Serious illness, injury or assault of a close relative in last 2 years	8.1	9.3	17.6	4.2	3.7	3.6	1.6	2.0	3.2	3.0	2.8	3.0	3.0	3.0	2.5
Illness, injury, bereavement, stress in last 2 years	6.6	8.1	12.0	-3.1	-3.5	-3.0	-0.8	-2.6	-3.0	-3.0	-3.0	-3.0	-3.0	-2.8	-2.6
Hip circumference	6.0	26.0	41.6	-6.5	-6.0	-5.8	-1.3	-3.2	-5.5	-5.6	-5.5	-5.2	-5.2	-5.1	-4.1
Smoking Status	5.8	13.8	27.5	3.3	3.9	4.0	0.1	3.4	3.9	4.0	5.2	3.6	3.8	3.0	3.9
Average weekly beer plus cider intake	5.2	7.5	12.4	3.5	3.0	3.0	0.7	3.1	2.8	2.9	2.9	2.9	2.7	2.5	1.6
Qualifications: CSEs or equivalent	4.8	6.4	8.3	2.0	2.8	2.7	1.4	2.9	2.5	2.7	2.8	2.8	2.7	2.0	2.8
Past tobacco smoking	4.8	8.8	16.0	-2.8	-3.3	-3.2	0.2	-3.1	-3.2	-3.2	-4.0	-3.1	-3.0	-2.3	-2.5
Hearing difficulty/problems with background noise	4.3	6.9	9.7	2.5	3.1	2.8	1.0	1.9	3.0	2.7	2.5	3.0	2.7	2.8	2.9
Breast cancer (self-reported)	4.2	5.0	6.6	1.5	2.0	2.3	2.2	2.4	2.3	2.6	2.1	2.4	2.5	2.4	1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.2	8.8	13.0	-2.8	-2.5	-3.0	-1.8	-2.5	-3.3	-3.5	-2.7	-3.5	-3.6	-2.7	-3.3
Number of self-reported non-cancer illnesses	4.0	6.9	10.6	2.4	2.0	2.3	1.6	2.0	2.9	3.0	2.8	2.8	2.8	3.1	3.2
Bipolar Disorder (2018)	3.8	6.0	8.6	2.5	2.9	2.4	1.8	2.0	2.7	2.7	1.6	2.8	2.7	2.7	2.1
BMI	3.8	22.1	40.3	-5.7	-6.3	-5.9	-1.4	-2.0	-5.1	-5.1	-5.1	-4.9	-4.9	-3.1	-4.0
Wears glasses or contact lenses	3.8	4.3	8.8	-3.0	-2.5	-2.3	0.3	-1.8	-2.4	-2.2	-2.1	-2.3	-2.1	-1.7	-1.4
Depression (Nagel 2018)	3.7	5.6	9.7	2.2	3.1	2.5	0.9	2.5	2.5	2.7	2.2	2.7	2.6	1.9	1.6
Medication: Amlodipine	3.7	5.2	7.0	2.3	2.1	2.3	1.7	2.0	2.4	2.6	2.3	2.5	2.5	1.8	2.4
Smoking status: Previous	3.7	5.5	9.3	2.4	2.6	2.4	-0.3	2.5	2.5	2.5	3.0	2.5	2.4	1.9	2.0
Osteoarthritis (self-reported)	3.6	4.7	8.0	-2.1	-2.1	-2.1	-0.8	-2.1	-2.2	-2.2	-1.6	-2.3	-2.1	-2.8	-2.8
Lung cancer (father)	3.2	3.7	5.7	1.4	1.6	1.8	1.6	1.9	1.9	2.2	1.6	2.3	2.3	1.8	2.4
Back pain experienced in last month	3.1	4.6	7.0	2.0	2.6	2.2	0.8	2.6	2.2	2.2	2.4	2.1	2.0	1.6	2.4
Father’s age at death	3.0	4.0	9.1	-1.7	-1.6	-1.9	-1.0	-2.0	-2.2	-2.1	-1.9	-2.1	-2.1	-3.0	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	3.0	4.6	9.4	1.6	2.4	2.4	0.9	2.0	2.3	2.4	3.1	2.1	2.3	1.8	1.7
Leg fat percentage (right)	3.0	10.7	20.9	-4.5	-4.6	-4.2	-0.1	-1.6	-3.5	-3.6	-3.6	-3.2	-3.3	-1.7	-2.3
Whole body fat mass	3.0	12.5	24.1	-4.9	-4.7	-4.2	-0.3	-1.8	-3.6	-3.8	-3.8	-3.5	-3.5	-2.7	-2.8
Overall health rating	2.9	6.1	9.0	1.6	1.5	1.9	2.7	2.9	2.6	2.6	2.2	2.7	2.5	3.0	2.9
Leg fat percentage (left)	2.9	10.6	20.7	-4.3	-4.5	-4.2	-0.4	-1.6	-3.5	-3.6	-3.5	-3.3	-3.3	-1.8	-2.2
Trunk fat mass	2.8	12.0	22.9	-4.8	-4.5	-4.1	-0.2	-1.8	-3.6	-3.7	-3.7	-3.5	-3.4	-3.0	-2.9
Body fat percentage	2.8	10.9	20.6	-4.4	-4.5	-4.0	0.2	-1.8	-3.4	-3.6	-3.5	-3.3	-3.3	-2.5	-2.6
Trunk fat percentage	2.7	10.7	19.2	-4.4	-4.4	-3.8	0.3	-1.9	-3.4	-3.5	-3.4	-3.3	-3.2	-2.9	-2.6
Multivitamins +/- minerals	2.7	3.4	4.6	2.1	2.0	2.0	0.3	2.1	1.9	2.0	2.1	1.9	1.9	1.6	1.1
Leg fat mass (right)	2.7	10.5	20.6	-4.5	-4.4	-4.0	-0.5	-1.5	-3.4	-3.5	-3.5	-3.2	-3.2	-2.0	-2.5
Leg pain on walking	2.7	3.3	4.5	-2.0	-2.1	-2.1	-1.4	-1.2	-2.0	-1.9	-1.7	-1.8	-2.1	-1.8	-1.6
Leg fat mass (left)	2.7	10.6	20.2	-4.5	-4.4	-4.0	-0.6	-1.6	-3.4	-3.5	-3.5	-3.3	-3.2	-2.1	-2.5
Arm fat mass (right)	2.6	10.6	20.7	-4.5	-4.5	-4.0	0.1	-1.2	-3.4	-3.5	-3.6	-3.1	-3.1	-2.5	-2.6
Shortness of breath walking on level ground	2.6	3.1	5.5	-1.8	-1.9	-1.8	0.7	-2.0	-1.7	-1.8	-1.8	-1.8	-1.8	-1.1	-2.4
Schizophrenia (2014)	2.5	5.5	8.9	2.9	3.0	2.6	0.7	1.5	2.6	2.3	1.8	2.4	2.4	2.1	2.9
Noisy workplace	2.5	3.1	4.7	1.0	1.4	1.6	2.0	2.2	2.0	1.8	1.5	2.0	2.0	2.0	1.1
Arm fat mass (left)	2.5	10.2	20.3	-4.5	-4.5	-3.9	0.2	-1.3	-3.3	-3.4	-3.5	-3.1	-3.0	-2.4	-2.4
Medication: Atorvastatin	2.5	3.0	4.4	1.5	2.0	2.0	1.4	1.8	1.8	1.8	2.1	1.9	1.8	1.5	1.2
Frequency of depressed mood in last 2 weeks	2.4	3.4	6.0	1.8	2.4	2.1	1.1	2.2	2.0	2.1	1.9	2.2	2.0	1.1	0.5
Body mass index (BMI)	2.4	10.3	22.3	-4.3	-4.7	-4.2	-0.4	-1.1	-3.4	-3.5	-3.5	-3.1	-3.1	-1.7	-2.3
Neuroticism (2016)	2.3	3.3	4.3	2.0	1.9	2.0	0.4	2.0	1.9	2.0	1.9	2.1	2.0	1.4	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.0	9.7	1.4	1.9	1.5	0.3	3.1	1.6	1.8	1.7	2.0	1.6	1.1	1.2
Waist circumference	2.3	8.4	13.9	-3.7	-3.6	-3.5	-1.0	-1.2	-3.1	-3.1	-3.1	-3.0	-3.0	-2.3	-2.6
Arm fat percentage (right)	2.3	8.9	18.9	-3.9	-4.3	-3.7	0.7	-1.4	-3.1	-3.1	-3.3	-2.8	-2.8	-2.0	-2.5
Arm fat percentage (left)	2.3	9.0	18.8	-4.0	-4.3	-3.7	0.6	-1.4	-3.1	-3.2	-3.4	-2.9	-2.9	-2.2	-2.3
Bipolar Disorder or Schizophrenia	2.2	5.3	7.9	2.8	2.8	2.5	0.9	1.2	2.6	2.4	1.6	2.5	2.5	2.6	2.4
Weight	2.2	10.6	22.7	-4.8	-4.1	-3.8	-0.9	-1.3	-3.4	-3.5	-3.5	-3.2	-3.1	-2.8	-2.7
Ever highly irritable/argumentative for 2 days	2.2	2.7	4.1	1.9	1.9	1.8	0.6	0.8	1.7	1.8	2.0	1.8	1.8	1.3	1.4
Medication: Blood pressure	2.2	4.1	5.6	2.1	2.2	2.0	0.7	1.1	2.2	2.2	2.1	2.2	2.2	2.0	2.4
Medication: Bendroflumethiazide	2.2	3.3	9.3	1.2	1.1	1.2	1.9	1.3	1.7	1.9	1.8	1.6	1.9	3.0	2.3
Ever depressed for a whole week	2.2	2.7	4.2	1.9	1.7	1.6	1.1	1.9	1.6	1.7	2.0	1.6	1.6	1.7	0.7
Systolic Blood Pressure	2.1	10.3	14.3	3.8	3.5	3.4	0.4	3.1	3.3	3.5	3.4	3.4	3.3	3.4	2.7
High blood pressure	2.1	5.8	9.2	2.2	1.9	1.9	1.8	2.6	2.5	2.7	2.5	2.5	2.5	3.0	2.4
Hypertension (Self-reported)	2.1	5.9	8.6	2.1	1.9	2.0	1.7	2.8	2.5	2.8	2.6	2.4	2.6	2.9	2.6
Loud music exposure frequency	1.9	2.1	2.9	1.6	1.5	1.6	1.1	1.1	1.6	1.5	1.2	1.7	1.7	0.7	1.6
Nervous feelings	1.8	3.4	4.9	1.7	1.7	1.8	1.6	2.1	1.8	2.0	1.4	2.2	1.9	1.7	2.2
Worrier / anxious feelings	1.8	3.5	6.0	1.9	1.7	1.7	0.8	2.3	1.9	2.1	1.6	2.1	1.9	2.4	1.5
Waist Hip Ratio (WHR)	1.7	7.5	12.8	3.3	3.1	2.8	0.4	2.5	2.7	3.1	3.6	2.5	2.5	2.9	2.0
Medication for hormone replacement therapy	1.7	1.9	2.7	-1.5	-1.6	-1.4	-0.2	-1.7	-1.3	-1.3	-1.2	-1.3	-1.2	-1.6	-1.6
Vitamin and mineral supplements	1.7	2.3	3.9	-1.8	-1.6	-1.8	0.2	-1.3	-1.6	-1.7	-2.0	-1.6	-1.6	-1.4	-0.6
Taking other prescription medications	1.7	2.6	5.3	1.2	1.4	1.5	1.7	1.3	1.6	2.0	2.3	1.5	1.4	1.1	1.8
Mouth/teeth dental problems: Mouth ulcers	1.7	2.7	11.8	-0.3	-0.6	-1.0	-3.4	-0.4	-1.4	-1.5	-0.5	-1.6	-1.7	-1.2	-2.7
Cardiovascular Disease	1.5	5.0	8.8	2.7	1.9	2.0	1.2	2.2	2.2	2.4	3.0	2.2	2.4	2.2	2.1
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	3.8	1.5	1.4	1.5	-1.0	1.9	1.2	1.2	1.3	1.2	1.3	0.6	0.3
Diabetes (mother)	1.5	2.0	3.6	-1.5	-1.6	-1.6	-1.9	-0.7	-1.6	-1.4	-1.1	-1.4	-1.6	-1.0	-0.9
Depression (self-reported)	1.5	1.8	3.6	1.3	1.3	1.3	0.2	1.9	1.3	1.4	1.5	1.4	1.4	1.4	0.9
Family relationship satisfaction	1.5	1.8	4.8	1.3	1.0	1.2	2.2	1.4	1.3	1.3	1.1	1.2	1.6	0.8	1.5
Eye problems/disorders: Glaucoma	1.5	1.8	3.1	-1.8	-1.3	-1.4	-1.4	-1.0	-1.6	-1.5	-1.2	-1.4	-1.4	-1.4	-0.7
Illnesses of father: High blood pressure	1.5	1.9	3.2	1.8	1.4	1.6	0.7	1.2	1.5	1.7	0.9	1.5	1.5	1.7	0.3
Number of operations (self-reported)	1.5	2.2	4.1	-1.7	-1.8	-1.4	-0.4	-0.6	-1.6	-1.5	-1.0	-1.6	-1.6	-2.0	-1.4
Age started oral contraceptive pill	1.5	1.9	4.7	0.6	0.9	1.0	1.4	2.1	1.1	1.4	0.7	1.5	1.3	2.2	1.4
Vascular/heart problems diagnosed by doctor	1.5	4.1	7.5	-1.7	-1.4	-1.5	-1.3	-2.3	-2.1	-2.3	-2.3	-2.0	-2.2	-2.7	-2.2
Cholesterol lowering medication	1.5	2.3	4.7	1.5	1.5	1.7	-0.6	0.9	1.6	1.5	2.2	1.5	1.5	1.2	1.8
Alzheimer’s Disease (in father)	1.4	1.6	2.6	1.4	1.6	1.6	-0.0	1.5	1.5	1.2	1.3	1.4	1.2	0.7	0.5
Body Mass Index (BMI) (2010)	1.4	1.9	3.6	-1.3	-1.6	-1.4	-1.9	-0.3	-1.5	-1.6	-1.1	-1.4	-1.6	-1.4	-0.6
Fed-up feelings	1.4	2.5	4.5	1.1	1.8	1.6	0.4	1.6	1.8	1.9	2.1	1.9	1.6	1.2	1.4
Ever had prostate specific antigen (PSA) test	1.4	1.6	4.3	1.1	1.5	1.1	1.2	1.2	1.1	1.3	1.2	1.2	1.2	0.3	2.1
Verbal and Numeric Reasoning (VNR)	1.3	3.0	5.7	-2.1	-2.4	-1.9	0.3	-1.1	-1.9	-1.8	-1.6	-2.1	-1.8	-1.7	-1.3
Hearing difficulty/problems: Yes	1.3	2.1	4.5	1.2	1.5	1.3	1.4	0.4	1.5	1.4	1.1	1.6	1.3	1.6	2.1
Supplements: Zinc	1.3	1.4	4.2	2.0	1.2	1.3	-0.4	0.3	1.3	1.4	0.9	1.2	1.2	1.4	0.0
Pain all over the body in last month	1.3	1.4	2.2	-1.1	-1.2	-1.3	0.1	-1.0	-1.3	-1.3	-1.4	-1.0	-1.4	-1.5	-0.9
Number of treatments/medications taken	1.2	2.2	3.4	1.3	0.9	1.2	1.4	1.3	1.4	1.8	1.7	1.5	1.6	1.5	1.8
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	3.0	1.3	1.2	1.7	0.5	1.1	1.5	1.4	1.7	1.3	1.3	0.6	0.6
Angina	1.2	1.6	2.9	-1.7	-1.4	-1.2	-1.4	-1.7	-1.1	-1.4	-0.5	-1.4	-1.4	-0.5	-0.7
Townsend deprivation index at recruitment	1.2	1.7	2.7	1.3	1.5	1.4	0.0	1.5	1.4	1.2	1.6	1.3	1.4	1.1	1.4
Current tobacco smoking	1.2	2.0	3.1	0.9	1.4	1.5	0.9	1.1	1.6	1.5	1.8	1.4	1.5	1.4	1.7
Had menopause	1.2	1.5	5.2	-2.3	-1.3	-1.3	-0.0	-1.4	-1.1	-1.3	-1.3	-1.0	-0.9	-1.0	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	2.4	-1.5	-1.5	-1.4	-1.0	-0.9	-1.3	-1.1	-0.9	-1.2	-1.2	-1.1	-0.8
Hayfever, allergic rhinitis or eczema	1.1	2.4	6.0	2.4	2.2	2.2	-0.3	1.0	1.7	1.2	0.9	1.7	1.7	0.6	0.1
Financial difficulties in last 2 years	1.1	1.4	2.5	1.3	1.6	1.3	-1.0	0.6	1.3	1.2	1.1	1.4	1.2	0.8	1.2
Neuroticism score	1.1	2.3	4.4	1.2	1.5	1.4	0.6	2.1	1.6	1.9	1.7	1.8	1.6	1.4	1.1
Alcohol intake versus 10 years previously	1.1	1.7	5.2	1.5	1.7	1.2	0.5	2.3	1.0	1.3	1.0	1.2	1.2	0.6	1.1
Falls in the last year	1.1	1.5	2.9	-1.7	-1.1	-1.3	-0.3	-0.9	-1.3	-1.4	-1.4	-1.2	-1.3	-1.2	-1.3
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	5.2	1.4	1.4	1.4	-0.3	1.2	1.5	1.7	2.3	1.2	1.3	0.5	1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	2.2	1.1	1.4	1.4	0.3	1.1	1.3	1.5	0.9	1.3	1.4	0.8	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	4.2	0.7	0.6	0.8	2.0	1.3	1.0	1.2	1.0	1.1	1.3	1.0	1.0
Chest pain or discomfort	1.1	1.6	4.6	-1.6	-1.1	-1.1	-1.1	-0.5	-1.4	-1.4	-0.3	-1.3	-1.4	-2.1	-0.9
Mineral and other dietary supplements	1.1	1.5	4.5	-1.4	-1.3	-1.2	0.5	-0.8	-1.2	-1.3	-1.0	-1.2	-1.2	-2.1	-0.6
Medication: Aspirin	1.1	1.5	3.1	1.3	0.8	0.9	-0.2	1.4	1.0	1.3	1.2	1.1	1.1	1.8	1.7
Smoking status: Current	1.1	1.8	2.9	0.8	1.3	1.4	0.6	1.1	1.5	1.5	1.7	1.3	1.4	1.4	1.6
Alcohol drinker status: Never	1.1	1.3	2.8	-1.2	-1.4	-1.1	0.2	-1.7	-1.1	-1.1	-0.7	-1.2	-1.2	-1.4	-0.9
HDL Cholesterol	1.0	1.6	5.6	-1.9	-1.0	-0.8	1.0	-0.1	-1.0	-1.2	-1.0	-0.9	-1.3	-2.4	-1.2
Hypothyroidism (self reported)	1.0	2.3	6.4	1.4	1.4	1.3	-0.1	1.2	1.4	1.8	2.5	1.3	1.3	0.3	2.2
Ever used hormone-replacement therapy (HRT)	1.0	1.3	4.3	-2.1	-1.3	-1.3	0.0	-0.3	-0.9	-1.2	-1.1	-1.0	-1.0	-0.6	-1.5
Diabetes (father)	1.0	1.2	2.5	-0.8	-0.9	-0.8	-0.9	-0.9	-1.2	-1.3	-1.6	-1.0	-1.1	-1.4	-1.1
Relative age voice broke	1.0	1.5	2.4	-1.2	-1.1	-1.4	0.5	-0.4	-1.3	-1.4	-0.5	-1.4	-1.5	-1.5	-1.5
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	4.7	0.8	0.6	0.8	2.2	0.8	1.0	1.2	0.0	1.2	1.3	1.1	0.5
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	3.0	-0.6	-1.0	-1.1	0.5	-1.1	-1.3	-1.1	-0.9	-1.3	-1.2	-1.7	-0.4
Leg predicted mass (left)	1.0	5.4	13.2	-3.6	-2.8	-2.6	-0.3	-0.7	-2.3	-2.3	-2.6	-2.1	-2.1	-2.3	-2.3
Happiness	1.0	1.2	2.2	1.3	0.8	1.4	-0.0	0.6	1.5	1.3	1.0	1.3	1.4	0.6	0.8
Medication: Lansoprazole	1.0	1.1	2.4	-1.2	-1.6	-1.2	0.7	-1.3	-1.0	-1.0	-1.0	-1.1	-0.9	-0.6	-0.4
Illnesses of mother	1.0	1.2	2.0	-0.5	-1.3	-1.4	0.6	-0.9	-1.4	-1.1	-1.2	-1.3	-1.2	-1.0	-0.9
Headache pain in last month	1.0	1.7	2.7	1.6	1.2	1.5	0.2	1.2	1.4	1.5	1.0	1.6	1.5	1.6	0.6
Exposure to tobacco smoke outside home	1.0	1.3	6.5	-0.7	-0.8	-0.9	-2.5	0.1	-1.0	-1.3	-0.2	-1.2	-1.3	-0.5	-1.1
Handedness (chirality/laterality): Left-handed	1.0	1.2	3.6	-0.7	-0.8	-1.2	-1.9	-0.2	-1.3	-1.1	-1.4	-1.0	-1.1	-1.0	-0.7
Crohns Disease (2017)	0.9	2.0	7.0	0.3	1.0	0.8	1.8	0.9	1.2	1.4	2.6	1.1	1.2	1.2	1.7
Leg fat-free mass (left)	0.9	4.9	12.3	-3.5	-2.6	-2.5	-0.3	-0.6	-2.2	-2.2	-2.4	-2.0	-2.0	-2.1	-2.1
Exposure to tobacco smoke at home	0.9	1.1	1.5	-1.0	-0.8	-1.0	-0.4	-0.9	-1.1	-1.2	-1.1	-1.2	-1.1	-1.2	-0.9
Supplements: Vitamin C	0.9	1.1	1.6	1.2	0.8	1.2	-1.0	0.9	1.1	1.1	1.0	1.1	1.0	1.1	0.3
Illnesses of father: Heart disease	0.9	1.3	4.5	-0.9	-0.9	-0.9	-1.4	-2.1	-0.8	-1.0	-0.9	-1.0	-1.1	-0.3	-1.3
Mood swings	0.9	1.6	2.9	0.7	1.4	1.2	-0.2	1.4	1.5	1.5	1.6	1.5	1.3	1.7	0.3
Neuroticism	0.8	2.0	3.1	1.1	1.8	1.4	-0.0	1.3	1.5	1.6	1.6	1.5	1.4	1.4	1.4
Average weekly fortified wine intake	0.8	1.0	2.0	-0.3	-0.8	-0.6	-1.1	-0.9	-0.9	-0.8	-1.2	-1.0	-0.8	-1.4	-1.4
Alcohol usually taken with meals	0.8	1.4	2.9	-1.4	-1.3	-1.3	-1.7	-1.1	-1.1	-1.0	-0.8	-1.1	-0.9	-0.6	-1.3
Tense / ‘highly strung’	0.8	1.4	2.2	1.3	1.2	1.2	0.4	1.2	1.2	1.5	1.4	1.2	1.2	1.0	1.1
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	2.2	-0.8	-1.2	-0.9	-1.5	-1.4	-1.2	-1.2	-0.9	-1.3	-1.1	-1.0	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.8	-0.5	-0.7	-0.8	0.7	-1.7	-1.1	-1.0	-0.9	-0.8	-0.9	-1.4	-0.4
Health satisfaction	0.8	1.0	6.2	-1.4	-1.4	-0.9	2.5	0.7	-0.4	-0.2	-0.8	-0.0	-0.5	0.3	-0.3
Angina (self-reported)	0.8	1.0	2.0	-1.3	-1.1	-0.9	-1.2	-1.4	-0.8	-1.1	-0.4	-1.1	-1.1	-0.3	-0.3
Alcohol intake frequency.	0.8	1.8	3.0	-1.6	-1.6	-1.3	0.2	-1.2	-1.5	-1.3	-1.0	-1.5	-1.3	-1.3	-1.7
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.2	-1.1	-0.6	-0.8	-1.5	-0.3	-1.2	-0.9	-0.0	-1.0	-1.2	-1.3	-0.1
Medication: Aspirin	0.8	1.0	2.7	1.1	0.5	0.7	-0.0	1.0	0.8	1.1	1.2	0.8	0.9	1.4	1.6
Guilty feelings	0.8	1.1	3.2	0.9	1.2	1.2	-0.1	1.6	0.8	1.1	1.8	0.9	0.9	-0.8	-0.1
Hearing aid user	0.8	0.9	1.3	0.9	0.9	1.0	1.1	0.5	1.0	1.0	0.8	1.1	1.0	0.9	0.8
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.1	1.4	0.8	1.1	0.4	0.7	1.0	1.2	0.7	1.1	1.1	1.3	0.7
Worry (Nagel 2018)	0.7	1.5	2.9	1.2	1.3	1.2	1.2	1.0	1.1	1.3	0.8	1.4	1.2	0.7	1.7
Allergy or Eczema	0.7	1.8	4.5	2.1	1.8	2.0	0.3	0.5	1.7	1.0	0.7	1.5	1.6	0.7	0.5
Hand grip strength (left)	0.7	1.7	3.2	0.4	1.7	1.5	0.6	1.0	1.4	1.4	1.6	1.4	1.6	0.2	1.8
Sensitivity / hurt feelings	0.7	1.3	3.4	0.3	0.8	0.8	0.4	1.7	0.9	1.2	1.9	0.9	0.9	1.7	0.8
Hand grip strength (right)	0.7	1.8	4.5	0.8	1.5	1.5	0.9	0.3	1.5	1.5	1.3	1.4	1.7	0.6	2.1
Maternal smoking around birth	0.7	1.0	2.7	1.2	1.2	1.1	0.1	-0.1	1.1	1.1	1.7	0.8	0.9	0.4	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	2.9	0.6	1.7	1.2	-0.8	1.1	0.9	0.9	1.6	0.9	0.7	-0.4	-0.1
Pulse wave reflection index	0.7	0.9	1.8	-0.5	-0.9	-1.2	-0.8	-1.0	-1.1	-0.9	-1.4	-1.0	-1.0	-0.5	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	3.0	0.4	0.2	0.6	0.9	0.9	1.0	0.9	0.6	0.9	0.9	1.7	0.9
Leg fat-free mass (right)	0.7	3.8	9.1	-3.0	-2.3	-2.1	-0.5	-0.6	-1.9	-1.9	-2.1	-1.8	-1.7	-2.0	-2.0
Eye problems/disorders: Cataract	0.7	0.8	2.8	-0.2	-0.9	-1.0	-1.7	-1.2	-0.7	-0.7	-0.9	-0.9	-0.9	-0.4	0.0
Leg predicted mass (right)	0.7	3.6	8.8	-3.0	-2.2	-2.1	-0.4	-0.5	-1.9	-1.9	-2.1	-1.7	-1.6	-2.0	-1.9
Basal metabolic rate	0.7	4.1	11.6	-3.4	-2.4	-2.3	-0.7	-0.2	-2.0	-2.0	-2.2	-1.8	-1.8	-1.8	-1.9
Pain experienced in last month	0.7	1.1	2.0	-1.0	-0.9	-0.7	-0.9	-1.3	-1.0	-1.1	-0.8	-1.1	-1.1	-1.2	-1.4
Pack years of smoking	0.7	1.0	1.7	-0.8	-1.3	-1.1	-1.1	-0.9	-0.9	-1.1	-1.3	-1.1	-1.0	-0.3	-0.6
Arm predicted mass (left)	0.7	3.5	11.7	-3.4	-2.2	-2.2	-0.9	-0.0	-1.8	-1.8	-2.0	-1.6	-1.6	-1.3	-1.6
Schizophrenia (2018)	0.6	1.2	2.4	1.6	1.5	1.2	-0.3	0.1	1.2	0.9	0.8	1.0	1.0	1.2	1.4
Schizophrenia vs Biploar Disorder	0.6	0.7	2.1	-1.0	-0.5	-0.6	0.2	-0.4	-0.8	-1.1	-0.4	-1.1	-1.0	-0.9	-1.4
Prostate Cancer	0.6	0.9	3.2	0.6	-0.3	-0.2	1.5	1.2	0.4	0.8	-0.7	0.6	0.9	1.8	0.9
Bipolar Disorder (2011)	0.6	0.6	1.3	0.8	0.7	0.6	-0.8	-0.1	0.8	0.8	0.4	0.7	0.9	1.2	0.7
Coronary Artery Disease (CAD)	0.6	0.8	1.5	-1.2	-1.0	-1.1	-1.0	-0.3	-0.7	-0.9	-0.7	-1.0	-0.9	-0.9	-0.1
Heel T-Score	0.6	4.7	12.1	-1.6	-2.5	-2.0	-3.5	-1.3	-2.2	-2.5	-2.5	-2.2	-2.1	-1.7	-0.6
Had other major operations	0.6	0.8	2.6	-0.7	-0.8	-0.5	-0.6	-0.1	-0.7	-0.6	0.0	-0.8	-0.8	-1.6	-1.6
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.6	0.8	0.6	0.8	0.9	1.3	0.8	0.9	1.2	0.7	0.8	0.9	0.1
Mouth/teeth dental problems	0.6	1.0	6.0	-0.6	-0.6	-0.5	2.5	-0.9	-0.4	-0.2	-1.3	-0.1	-0.2	-1.2	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	2.8	0.9	1.0	0.9	0.8	1.7	1.1	1.0	1.1	1.0	0.9	0.3	0.3
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	5.4	-1.4	-0.8	-0.9	-1.6	-1.2	-1.4	-1.4	-0.6	-1.6	-1.6	-2.3	-1.8
Birth weight of first child	0.6	1.0	5.1	0.0	-0.4	-0.1	0.7	1.1	0.7	0.9	1.4	0.7	0.8	2.3	0.8
Heart disease (mother)	0.6	0.7	1.4	-0.0	0.7	1.1	0.2	1.2	1.1	0.8	0.8	1.1	1.0	0.3	-0.2
Loneliness, isolation	0.6	0.9	4.3	0.0	0.1	0.2	0.8	2.1	0.7	1.0	0.5	1.0	1.0	1.1	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	4.3	-0.2	0.4	0.2	-2.1	-0.1	-0.2	-0.4	0.4	-0.4	-0.4	-0.7	-1.7
Commuting to job workplace: Walk	0.6	0.6	1.2	1.0	1.1	1.1	-0.3	0.4	0.9	0.7	0.8	0.8	1.0	0.6	0.4
Medication for cholesterol	0.6	1.0	1.9	-1.4	-1.0	-1.0	0.3	-0.2	-1.1	-1.1	-1.3	-1.0	-1.1	-0.7	-0.9
Arm fat-free mass (left)	0.6	3.1	10.5	-3.2	-2.1	-2.1	-1.1	0.2	-1.7	-1.7	-1.9	-1.5	-1.5	-1.1	-1.5
Fractured/broken bones in last 5 years	0.6	0.7	3.9	-1.3	0.2	-0.3	0.5	-0.7	-0.6	-0.7	0.3	-0.6	-0.7	-2.0	-0.7
Supplements: Calcium	0.6	0.6	2.4	0.5	1.1	0.6	-0.1	0.0	0.8	0.8	1.5	0.5	0.6	1.3	0.2
Intelligence (Savage-Jansen 2018)	0.5	1.5	2.4	-1.3	-1.5	-1.3	-0.9	-0.8	-1.4	-1.3	-0.8	-1.6	-1.5	-0.9	-1.1
Neuroticism (Nagel 2018)	0.5	1.1	2.1	0.6	1.3	1.0	0.0	1.0	1.0	1.2	1.5	1.1	1.0	0.8	1.3
Major Depression (MDD)	0.5	0.7	1.7	0.1	0.8	0.6	0.6	1.3	0.6	0.8	1.1	0.9	0.8	0.4	1.1
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.5	0.3	0.0	-0.4	-1.5	-1.6	-0.6	-0.7	-0.3	-0.7	-0.7	0.4	0.1
Type 2 Diabetes (T2D) (2018)	0.5	0.9	2.1	1.4	1.1	1.2	0.7	-0.1	1.0	0.8	1.4	0.9	1.0	0.6	0.7
Pack years adult smoking proportion	0.5	0.8	1.4	-0.6	-1.1	-1.0	-1.1	-0.6	-0.8	-1.0	-1.2	-0.9	-0.9	-0.5	-0.6
Hair/balding pattern: Pattern 2	0.5	0.6	2.0	-1.4	-0.8	-0.7	-0.2	-0.1	-0.5	-0.7	-1.0	-0.4	-0.7	-0.3	-1.2
Heart attack	0.5	0.7	1.6	-0.3	-0.7	-0.7	-0.6	-1.3	-1.1	-0.8	-0.8	-1.0	-0.9	-0.9	-0.6
Allergy	0.5	1.2	2.6	-1.6	-1.5	-1.6	-0.1	-0.6	-1.3	-0.9	-0.5	-1.4	-1.3	-0.4	-0.2
Time employed in main current job	0.5	0.5	3.1	-0.3	0.1	0.1	1.8	-0.1	0.1	0.5	0.3	0.2	0.4	-1.4	0.9
Hair/balding pattern: Pattern 3	0.5	0.8	2.8	1.7	1.0	1.1	0.3	0.2	0.9	0.8	1.0	0.7	0.9	0.2	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	2.0	0.6	0.6	0.5	0.1	1.4	0.6	1.1	0.6	0.9	0.9	0.6	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	6.0	-1.3	-0.4	-0.5	-1.2	-0.7	-1.1	-1.2	-0.5	-1.3	-1.4	-2.4	-1.5
Medication: Paracetamol	0.5	0.8	1.9	0.6	0.6	0.5	-0.4	0.5	1.0	0.9	1.3	0.7	0.8	1.2	1.4
Comparative body size at age 10	0.5	1.3	8.1	0.3	0.1	0.2	0.7	2.8	0.7	0.8	0.2	0.9	0.9	2.0	0.9
Worry too long after embarrassment	0.5	0.8	2.0	1.2	0.9	1.0	-1.1	1.0	0.6	0.6	1.4	0.6	0.5	-0.0	0.7
Number of children fathered	0.5	0.5	1.4	0.0	0.5	0.5	1.2	0.8	0.4	0.9	1.0	0.6	0.8	0.0	0.9
Medication for pain relief, constipation, heartburn	0.5	0.9	2.0	-0.8	-0.3	-0.4	0.4	-1.2	-0.7	-1.2	-1.1	-0.8	-1.0	-1.4	-1.4
Medication: Blood pressure	0.5	0.8	3.3	0.6	-0.0	0.4	1.8	1.0	0.7	1.1	0.7	0.6	1.0	1.0	0.4
Mean time to correctly identify matches	0.5	0.9	2.6	-0.2	-0.6	-1.0	-0.8	-1.5	-1.0	-0.8	-1.6	-0.8	-1.0	0.2	-0.9
Whole body fat-free mass	0.5	2.8	9.2	-3.0	-1.8	-1.8	-0.7	-0.0	-1.6	-1.6	-1.9	-1.4	-1.4	-1.5	-1.6
Friendships satisfaction	0.5	0.6	1.9	-0.4	-0.9	-0.7	0.4	-1.0	-0.8	-0.6	-0.8	-0.7	-0.6	-1.4	-0.8
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.8	0.3	0.6	0.8	0.4	1.4	0.8	0.8	0.8	1.0	0.9	-0.3	1.1
High cholesterol (Self-reported)	0.5	0.8	1.7	1.2	1.0	1.0	0.3	0.4	1.0	1.0	1.3	1.0	1.1	0.3	0.6
Irritable Bowel Disease (IBD)	0.4	1.0	4.0	0.2	0.7	0.5	1.7	0.5	0.8	1.0	2.0	0.6	0.7	1.1	1.0
Reaction Time	0.4	0.8	2.6	-0.0	-0.4	-0.9	-0.4	-1.3	-1.1	-0.8	-1.6	-0.9	-1.0	-0.6	-0.5
Medication: Metformin	0.4	0.6	2.1	-0.6	-1.0	-0.7	1.5	0.6	-0.6	-0.4	0.0	-0.6	-0.5	-0.6	-1.2
Impedance of leg (left)	0.4	1.7	4.4	1.8	2.1	1.8	-0.2	0.3	1.2	1.2	1.6	1.0	1.0	0.2	1.4
Number of incorrect matches in round	0.4	0.7	3.2	-0.2	-0.7	-1.0	0.2	-1.2	-0.9	-0.6	-1.8	-0.5	-0.7	-0.1	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	4.4	0.0	-0.8	-0.3	-2.1	-0.8	-0.8	-0.8	-1.0	-0.5	-0.7	-0.9	-0.8
Medication: Ramipril	0.4	0.5	1.9	-0.9	-0.8	-0.9	1.4	-0.2	-0.6	-0.4	-0.2	-0.6	-0.5	-0.4	0.2
Pulse rate	0.4	0.6	6.3	0.2	-0.5	0.0	2.5	0.0	0.3	0.3	0.8	0.1	0.3	-0.1	0.1
Arm fat-free mass (right)	0.4	2.0	7.6	-2.8	-1.6	-1.6	-1.1	0.4	-1.2	-1.3	-1.5	-1.1	-1.1	-0.9	-1.0
Qualifications: College or University degree	0.4	1.2	3.3	-0.6	-1.5	-0.8	0.4	-0.3	-1.0	-0.9	-1.2	-1.0	-0.8	-1.8	-1.8
Eye problems/disorders: None of the above	0.4	0.5	0.9	-0.8	-0.4	-0.7	0.6	-0.2	-0.9	-0.8	-0.4	-0.7	-0.9	-0.9	-0.9
Emphysema/chronic bronchitis	0.4	0.4	1.4	-0.3	-0.6	-0.6	0.7	-0.3	-0.1	-0.2	-1.2	-0.1	-0.2	0.8	1.2
Medication: Omeprazole	0.4	0.4	0.7	0.6	0.7	0.8	0.8	0.2	0.8	0.8	0.6	0.6	0.7	0.9	0.2
Medication: Seretide 50 evohaler	0.4	0.5	1.6	-0.7	-0.8	-0.6	1.2	-0.8	-0.4	-0.4	-1.3	-0.3	-0.1	0.1	0.4
Arm predicted mass (right)	0.4	2.2	8.2	-2.9	-1.7	-1.7	-1.0	0.3	-1.3	-1.4	-1.7	-1.2	-1.2	-1.0	-1.0
Age at last live birth	0.4	0.6	3.3	0.0	0.5	0.5	0.9	1.8	0.4	0.7	0.8	0.8	0.8	-0.2	-0.5
Qualifications: nursing, teaching	0.4	0.6	1.1	1.0	0.6	1.1	0.4	0.5	0.8	0.8	0.2	0.7	0.9	0.3	1.0
Medication: Gliclazide	0.4	0.4	1.8	0.8	0.5	0.7	0.5	1.3	0.6	0.3	0.8	0.3	0.4	0.1	-0.4
Illnesses of father: None of the above (group 1)	0.4	0.5	3.5	-0.1	-0.7	-0.5	0.7	0.5	-0.7	-0.3	-0.0	-0.3	-0.2	-1.9	0.6
Whole body water mass	0.4	2.4	8.6	-2.9	-1.7	-1.7	-0.6	0.2	-1.4	-1.4	-1.7	-1.2	-1.2	-1.4	-1.5
Average weekly champagne plus white wine intake	0.4	0.5	1.4	0.3	0.6	0.8	-0.0	0.6	0.7	0.9	1.2	1.0	0.9	-0.6	-0.2
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.6	-0.2	-0.5	-0.6	-0.6	-1.3	-0.9	-0.7	-0.6	-0.9	-0.8	-0.7	-0.4
Crohns Disease (2012)	0.3	0.5	1.3	-1.2	-0.5	-0.6	0.9	-0.7	-0.2	-0.0	1.1	-0.4	-0.2	0.4	0.9
Primary Biliary Cirrhosis	0.3	0.4	1.3	-0.9	-0.7	-0.7	1.0	0.1	-0.2	0.1	1.1	-0.3	-0.2	-0.3	0.4
Rheumatoid Arthritis	0.3	0.4	1.6	-0.4	0.0	-0.0	1.3	0.8	0.1	0.7	0.9	0.0	0.4	-0.0	0.7
Blood Eosinophil Count	0.3	2.2	11.2	0.9	-0.0	0.2	-2.3	-3.3	-0.6	-1.0	-1.4	-0.8	-0.5	-2.0	-0.1
Blood Platelet Count	0.3	3.1	9.7	-3.1	-2.0	-1.2	-0.2	2.0	-1.4	-1.5	0.4	-1.2	-1.3	-2.8	-1.3
Lung FEV1/FVC ratio	0.3	1.3	2.5	-1.0	-1.6	-1.2	0.8	0.5	-1.5	-1.0	-0.4	-1.3	-1.1	-1.5	-1.3
Chronotype (morning person)	0.3	0.6	2.6	-1.6	-0.8	-0.6	1.6	-0.5	-0.5	-0.1	-0.4	-0.2	-0.1	-0.7	-0.4
Tanning	0.3	3.8	6.4	1.9	1.8	1.9	1.7	2.5	1.9	2.1	1.1	2.3	2.1	2.3	1.3
Average weekly spirits intake	0.3	0.4	0.7	-0.6	-0.6	-0.6	-0.4	-0.0	-0.7	-0.6	-0.7	-0.7	-0.7	-0.8	-0.1
Severe depression (siblings)	0.3	0.3	0.8	-0.7	-0.6	-0.7	-0.8	0.3	-0.4	-0.4	-0.9	-0.3	-0.5	-0.4	0.1
Impedance of leg (right)	0.3	1.6	3.9	1.5	2.0	1.7	0.3	0.5	1.3	1.1	1.4	1.1	1.0	0.4	1.5
Medication: Levothyroxine sodium	0.3	0.5	3.6	0.2	0.4	0.3	-0.7	0.1	0.3	0.7	1.0	0.4	0.2	-0.3	1.9
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	0.8	0.4	0.5	0.5	-0.3	0.8	0.9	0.4	0.2	0.7	0.6	0.9	0.3
Illnesses of siblings	0.3	0.5	1.4	1.2	0.9	0.8	0.9	0.7	0.5	0.5	0.6	0.6	0.5	-0.1	0.3
Trunk fat-free mass	0.3	1.6	6.4	-2.5	-1.2	-1.3	-1.0	0.5	-1.1	-1.1	-1.4	-0.9	-0.9	-0.9	-1.2
Qualifications: A levels/AS levels or equivalent	0.3	0.7	3.4	0.6	-0.5	-0.1	-0.1	-1.0	-0.6	-0.4	-0.9	-0.8	-0.6	-1.9	-0.7
Pulse wave Arterial Stiffness index	0.3	0.4	2.9	0.2	-0.1	-0.1	1.7	-0.3	0.2	0.4	0.4	0.2	0.2	0.1	0.9
Trunk predicted mass	0.3	1.7	6.9	-2.6	-1.3	-1.4	-1.0	0.5	-1.1	-1.1	-1.5	-1.0	-1.0	-1.0	-1.2
Length of working week for main job	0.3	0.3	0.6	-0.8	-0.7	-0.8	-0.7	0.1	-0.5	-0.6	-0.3	-0.7	-0.7	-0.5	-0.3
Peak expiratory flow (PEF)	0.3	0.7	4.0	-1.1	-0.5	-0.4	0.2	-0.0	-0.7	-0.5	0.2	-0.7	-0.7	-2.0	-0.8
Blood clot in the leg (DVT)	0.3	0.4	1.6	-1.1	-0.7	-0.7	1.3	-0.2	-0.2	-0.0	-0.2	-0.1	-0.1	0.2	-0.7
Pulse wave peak to peak time	0.3	0.4	2.8	-0.3	0.2	0.1	-1.7	0.3	-0.2	-0.4	-0.5	-0.2	-0.3	-0.4	-1.1
Pulse rate, automated reading	0.3	1.1	11.1	-0.4	-1.0	-0.2	3.3	0.5	0.2	0.2	0.4	0.1	0.3	0.0	0.5
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.6	-1.3	-0.7	-0.9	-0.3	0.3	-0.4	-0.4	-0.3	-0.5	-0.8	0.2	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	2.4	-0.4	-0.3	-0.4	-1.0	0.4	-0.7	-0.5	-0.6	-0.6	-0.6	-1.6	-0.9
Long-standing illness, disability or infirmity	0.3	0.4	1.6	0.4	0.4	0.5	1.3	0.8	0.7	0.5	0.6	0.4	0.4	-0.2	0.7
Ever taken oral contraceptive pill	0.3	0.4	3.1	0.2	0.1	0.0	-1.8	1.0	-0.1	-0.2	0.1	-0.1	-0.2	-0.1	0.3
Mother’s age at death	0.3	0.4	1.3	0.5	1.1	0.8	0.3	0.9	0.6	0.6	0.1	0.7	0.7	-0.1	0.4
Tinnitus: Yes, now most or all of the time	0.3	0.4	2.1	-0.0	-0.3	-0.3	-1.4	-0.6	-0.4	-0.8	0.1	-0.8	-0.7	-0.1	-0.6
Commuting to job workplace: Public transport	0.3	0.4	1.0	-0.0	-0.7	-0.3	-0.3	-1.0	-0.4	-0.5	-0.7	-0.6	-0.3	-0.8	-0.9
Medication: Lisinopril	0.3	0.3	1.5	-0.0	0.2	0.4	-1.1	0.7	0.3	0.2	0.4	0.2	0.3	0.0	-1.2
Commuting to job workplace: Cycle	0.3	0.4	1.2	-0.1	-0.6	-0.5	0.6	-1.1	-0.6	-0.2	-0.6	-0.6	-0.5	-0.7	-0.4
Basal cell carcinoma (self-reported)	0.3	0.4	1.5	1.2	0.7	0.8	-1.1	-0.1	0.5	0.1	-0.2	0.4	0.3	-0.4	0.0
Alcohol drinker status: Previous	0.3	0.3	2.2	0.7	-0.1	0.2	0.4	0.0	0.5	0.4	0.1	0.3	0.6	1.5	0.2
Impedance of whole body	0.3	1.6	3.5	1.6	1.8	1.9	1.1	-0.4	1.1	1.1	1.4	1.0	0.9	-0.6	1.1
Depressed Affect (Nagel 2018)	0.2	0.4	1.3	-0.3	0.6	0.3	-0.2	0.4	0.6	0.7	0.6	0.8	0.7	1.1	0.6
Ovarian Cancer	0.2	0.3	1.1	0.3	0.8	0.7	-0.2	1.0	0.4	0.3	1.0	0.3	0.4	-0.3	-0.0
Fasting Glucose	0.2	0.2	0.9	0.5	0.0	-0.2	-0.9	0.1	-0.1	-0.3	-0.2	-0.3	-0.3	0.3	-0.9
HbA1C	0.2	0.3	0.8	0.5	0.4	0.1	-0.8	-0.9	-0.8	-0.0	-0.1	0.1	0.4	0.3	-0.5
LDL Cholesterol	0.2	0.4	0.9	0.5	0.7	0.6	0.8	0.6	0.5	0.5	0.9	0.4	0.6	0.7	0.4
Lung FVC	0.2	1.2	6.6	-1.1	-0.0	-0.3	-2.6	-0.7	-0.7	-1.1	-0.4	-1.1	-1.1	-1.2	-0.5
Ever had hysterectomy (womb removed)	0.2	0.3	0.7	0.4	0.2	0.6	0.3	0.6	0.4	0.5	0.3	0.5	0.6	0.5	0.8
Systolic blood pressure, automated reading	0.2	0.5	1.3	0.4	0.8	0.7	-0.6	0.8	0.7	0.5	0.3	0.7	0.6	1.2	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	4.3	0.2	-0.6	-0.2	-2.1	-0.3	-0.4	-0.5	-0.7	-0.2	-0.4	-0.2	-0.3
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.2	-0.4	0.5	0.1	0.5	-0.4	0.1	0.2	0.1	0.2	0.1	-1.1	-0.6
Supplements: Glucosamine	0.2	0.3	1.6	0.8	0.6	0.3	-0.5	0.3	0.3	0.4	0.3	0.4	0.6	1.3	0.2
Medication: Atenolol	0.2	0.3	0.8	0.3	0.8	0.6	-0.3	0.2	0.6	0.4	0.4	0.6	0.5	0.3	0.9
Chronic bronchitis/emphysema (father)	0.2	0.2	1.5	-0.0	0.2	0.0	-0.4	0.4	0.3	0.1	0.4	0.0	0.0	1.2	0.1
Forced vital capacity (FVC)	0.2	0.7	3.2	-0.4	0.4	0.2	-1.8	-0.6	-0.3	-0.5	0.1	-0.6	-0.7	-1.4	-0.8
Medication: Simvastatin	0.2	0.3	0.9	-0.2	-0.9	-0.3	0.9	0.0	-0.2	-0.0	0.9	-0.2	-0.0	-0.5	0.6
Fluid intelligence score	0.2	0.5	1.5	-0.4	-1.1	-0.5	1.2	0.2	-0.6	-0.4	-1.0	-0.6	-0.4	-0.5	-0.2
Impedance of arm (right)	0.2	0.9	2.4	1.0	1.2	1.3	1.6	-0.8	0.5	0.5	0.9	0.4	0.4	-1.4	-0.3
Number of live births	0.2	0.3	1.7	-1.3	-0.6	-0.5	0.3	0.2	-0.4	-0.3	0.1	-0.1	-0.3	-0.8	-0.3
Mouth/teeth dental problems: Dentures	0.2	0.4	1.9	0.0	0.2	0.3	-1.2	0.5	0.4	0.3	0.7	0.3	0.4	1.4	-0.3
Impedance of arm (left)	0.2	1.2	3.4	1.1	1.3	1.6	1.8	-0.7	0.7	0.7	0.9	0.6	0.6	-1.4	0.3
Breastfed as a baby	0.2	0.3	1.4	0.3	0.5	0.5	1.2	0.3	0.4	0.4	-0.2	0.6	0.6	0.0	0.6
Hair/balding pattern: Pattern 4	0.2	0.4	1.0	0.7	0.7	0.4	0.5	0.6	0.7	0.6	0.4	0.7	0.5	1.0	0.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.3	-0.2	-0.5	-0.4	-0.3	0.0	-0.4	-0.6	-0.4	-0.5	-0.5	-1.0	-1.1
Birth weight	0.2	0.5	1.8	-1.3	0.3	0.2	1.1	0.6	0.2	0.1	1.0	0.3	0.2	-0.2	1.0
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.6	-0.8	-0.6	-0.4	1.3	0.0	-0.3	-0.0	0.1	-0.0	-0.2	0.0	-0.1
High blood pressure (siblings)	0.2	0.3	1.1	-1.1	-0.6	-0.7	-0.1	-0.3	-0.5	-0.4	-0.8	-0.4	-0.3	0.1	-0.5
Forced vital capacity (FVC), Best measure	0.2	0.6	2.6	-0.3	0.7	0.6	-1.5	0.0	-0.1	-0.3	0.4	-0.3	-0.4	-1.6	-0.7
Number of full brothers	0.2	0.3	1.9	-1.4	-0.6	-0.7	0.3	0.1	-0.3	-0.4	0.3	-0.5	-0.3	0.2	0.0
Age at first live birth	0.2	0.4	1.9	-0.3	-0.3	-0.4	-0.0	0.7	-0.7	-0.3	-0.6	-0.4	-0.4	-1.2	-1.4
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.9	0.3	0.4	0.2	-0.8	-1.0	0.3	0.1	-0.4	0.2	0.3	0.4	0.3
Neck or shoulder pain in last month	0.2	0.3	0.6	0.7	0.7	0.6	-0.2	-0.1	0.7	0.4	0.8	0.5	0.7	0.1	0.2
Migraine (self-reported)	0.2	0.2	1.1	0.7	0.3	0.3	-0.3	-1.1	0.1	0.3	-0.1	0.2	0.2	0.7	-0.4
Knee pain experienced in last month	0.2	0.3	1.4	-0.5	-0.3	-0.3	0.5	1.0	0.1	0.4	0.1	0.3	0.2	1.2	0.4
Ever had bowel cancer screening	0.2	0.2	1.6	0.1	-0.2	-0.1	1.3	-0.3	0.1	0.1	0.0	0.3	0.2	0.6	0.8
Financial situation satisfaction	0.2	0.2	0.6	0.4	0.8	0.6	-0.2	0.3	0.7	0.5	0.1	0.6	0.7	0.1	0.4
Irritability	0.2	0.3	1.3	-0.6	0.5	0.2	-1.1	0.4	0.1	0.0	0.5	0.2	-0.0	-0.5	-0.9
Diastolic blood pressure, automated reading	0.2	0.7	1.3	1.0	0.9	1.0	0.8	1.2	0.8	0.7	0.3	0.9	0.9	0.1	0.4
Unable to work because of sickness or disability	0.2	0.2	0.8	-0.2	0.1	-0.1	-0.8	0.6	-0.2	-0.2	-0.1	-0.3	-0.5	-0.9	-0.7
Myopia	0.2	0.3	2.1	0.5	0.2	0.3	-0.4	-1.4	0.4	0.3	0.3	0.2	0.2	0.2	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	2.2	-0.8	-0.3	-0.3	1.5	0.2	0.2	0.4	0.3	0.2	0.2	0.7	-0.1
Alzheimer’s Disease (in mother)	0.1	0.1	0.5	0.4	0.4	0.1	-0.2	-0.4	0.3	0.0	-0.5	0.4	-0.0	0.7	-0.1
Alzheimer’s Disease (including proxy)	0.1	0.2	0.8	0.9	0.8	0.6	-0.4	0.2	0.4	0.1	-0.2	0.5	0.1	0.1	-0.3
Ulcerative Colitis (UC)	0.1	0.1	1.0	-0.3	-0.2	-0.2	1.0	-0.2	-0.1	-0.1	0.3	-0.3	-0.2	0.2	-0.2
Breast Cancer	0.1	0.4	1.0	-0.3	-0.9	-0.5	0.3	-1.0	-0.5	-0.7	-0.1	-0.5	-0.5	-0.8	0.4
Age at First Birth	0.1	0.2	1.0	-0.1	0.1	0.1	-0.9	0.1	-0.1	-0.0	-0.2	-0.2	-0.3	-0.4	-1.0
Mean Putamen Volume	0.1	0.2	0.5	0.6	0.4	0.3	-0.6	-0.5	0.2	0.2	-0.0	0.1	0.1	0.2	-0.7
Lupus	0.1	0.2	1.1	0.1	0.0	0.1	-0.7	-0.0	0.2	0.1	1.0	-0.0	0.0	0.1	-0.6
Triglycerides	0.1	0.1	0.6	0.3	-0.2	-0.2	-0.8	-0.3	-0.1	-0.0	0.4	-0.3	0.0	0.6	-0.2
Ulcerative Colitis	0.1	0.2	0.9	0.1	0.2	-0.1	0.7	0.4	0.0	0.2	0.7	-0.2	-0.0	0.9	-0.2
Blood Red Count	0.1	1.4	10.0	1.6	-0.3	-0.0	-0.4	-3.2	-0.2	-0.7	-1.7	-0.1	-0.1	-0.5	-0.1
Blood White Count	0.1	0.8	3.2	0.8	1.0	1.0	0.7	-1.1	0.4	0.4	1.8	0.2	0.4	-1.2	0.3
Height	0.1	1.5	8.1	-2.9	0.3	-0.1	-1.9	-0.8	-0.5	-0.7	-0.1	-0.8	-0.6	-1.9	-0.7
Respiratory disease	0.1	0.2	1.0	0.6	-0.2	0.1	0.5	-1.0	0.2	0.1	-0.3	0.4	0.3	0.3	0.7
Relative age of first facial hair	0.1	0.2	1.0	-0.1	0.2	0.2	0.3	0.7	0.1	-0.0	1.0	-0.1	-0.1	0.1	0.8
Medication: Co-codamol	0.1	0.2	0.7	0.3	0.4	0.6	-0.1	0.2	0.0	-0.0	0.8	0.0	-0.1	-0.8	-0.1
Age when periods started (menarche)	0.1	0.3	1.7	-0.7	0.3	0.3	1.3	0.6	0.2	0.1	0.5	0.3	0.4	0.3	-0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.9	-0.5	0.4	0.2	0.9	-0.3	0.4	0.2	0.0	0.2	0.2	0.2	-0.3
Stomach or abdominal pain in last month	0.1	0.1	0.6	-0.4	-0.3	-0.1	-0.7	-0.0	-0.3	-0.2	0.2	-0.1	-0.3	-0.6	-0.2
Sitting height	0.1	0.5	2.4	-0.4	0.2	0.2	-1.1	-0.9	-0.2	-0.5	-0.8	-0.3	-0.3	-1.6	-0.6
High blood pressure (mother)	0.1	0.2	0.6	0.6	0.3	0.6	-0.8	-0.6	0.5	0.1	0.1	0.2	0.4	-0.1	0.0
Qualifications: None of the above	0.1	0.2	0.8	-0.9	-0.4	-0.5	0.7	-0.2	-0.4	-0.4	-0.0	-0.4	-0.5	-0.3	-0.2
Diabetes (self-reported)	0.1	0.2	0.7	0.7	0.0	0.2	0.5	0.8	0.2	0.2	0.6	0.1	0.4	0.4	0.1
Asthma	0.1	0.3	0.9	1.0	0.2	0.5	-0.0	-0.0	0.5	0.4	0.6	0.7	0.6	0.4	0.8
Medication: Cholesterol lowering	0.1	0.2	1.5	-0.1	-0.6	-0.2	1.2	0.0	-0.2	0.0	0.2	-0.1	0.1	-0.3	0.1
Prospective memory result	0.1	0.2	0.9	-0.6	-0.1	-0.3	0.8	0.9	-0.2	-0.0	0.1	0.0	-0.2	0.3	-0.2
Standing height	0.1	0.9	5.6	-1.4	0.9	0.5	-0.9	-0.4	-0.2	-0.2	-0.3	-0.3	-0.2	-2.4	-0.8
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	1.4	0.2	0.7	0.4	-1.2	-0.1	0.3	0.1	-0.1	0.4	0.0	0.4	0.3
Glaucoma (self-reported)	0.1	0.1	0.7	-0.8	-0.3	-0.4	0.0	-0.2	-0.4	-0.3	-0.3	-0.2	-0.3	-0.6	0.2
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.6	0.2	-0.3	-0.1	-0.3	-0.7	-0.3	-0.4	-0.5	-0.1	-0.3	-0.7	0.2
Wheeze or whistling in the chest in last year	0.1	0.2	1.3	0.4	0.3	0.1	0.5	0.2	0.4	0.3	0.0	0.5	0.5	0.5	1.1
Medication: Ibuprofen	0.1	0.2	0.6	-0.2	-0.5	-0.6	0.1	0.6	-0.5	0.1	-0.7	0.1	-0.0	0.2	-0.1
Comparative height size at age 10	0.1	0.6	2.5	-1.6	0.3	0.1	1.3	0.0	-0.0	0.2	-0.7	-0.0	0.1	-1.4	-0.4
Number of full sisters	0.1	0.1	0.3	0.2	0.1	0.3	-0.2	0.4	0.4	0.4	0.6	0.4	0.4	0.1	0.5
Suffer from ‘nerves’	0.1	0.2	1.6	0.1	0.2	0.2	-0.6	1.3	-0.1	0.3	0.4	0.4	0.1	0.1	-0.3
Had major operations	0.1	0.1	0.4	-0.2	-0.2	-0.2	-0.4	0.7	-0.3	-0.4	0.0	-0.2	-0.2	-0.3	0.5
Illnesses of siblings: Diabetes	0.1	0.2	0.5	-0.2	-0.5	-0.5	-0.5	-0.7	-0.1	-0.2	-0.5	-0.0	-0.3	0.5	-0.0
Average weekly red wine intake	0.1	0.1	1.0	0.4	0.2	0.1	-1.0	-0.0	-0.1	-0.2	-0.5	-0.1	-0.1	-0.1	0.2
Diabetes diagnosed by doctor	0.1	0.1	0.5	0.1	-0.3	-0.2	0.6	0.7	-0.1	-0.1	0.5	-0.1	0.0	0.2	-0.1
Asthma (self-reported)	0.1	0.2	0.6	0.8	-0.0	0.3	0.4	-0.1	0.4	0.4	0.3	0.6	0.5	0.3	0.8
Osteoporosis (self-reported)	0.1	0.1	0.4	-0.5	-0.2	-0.4	0.2	0.3	-0.1	0.0	0.7	-0.2	-0.4	0.5	0.0
Miserableness	0.1	0.1	0.8	-0.1	0.4	-0.1	-0.6	-0.3	0.1	-0.0	0.4	0.1	-0.1	-0.0	-0.9
Medication: Paracetamol	0.1	0.2	0.6	-0.6	-0.7	-0.8	-0.5	-0.5	-0.3	-0.4	-0.4	-0.3	-0.3	0.3	0.2
Risk taking	0.1	0.2	0.9	0.5	0.2	-0.1	0.6	1.0	0.1	0.4	-0.4	0.3	0.3	0.1	0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	0.1	0.3	0.3	-0.1	-0.0	0.4	0.3	0.3	0.1	0.1	0.5	-0.3
Heart disease (siblings)	0.1	0.1	0.5	-0.1	0.2	0.2	-0.6	-0.1	-0.0	-0.1	0.7	-0.1	0.0	-0.5	-0.3
Hair Pigment	0.0	1.0	7.4	-2.7	-0.4	-0.5	0.3	-0.1	-0.7	-0.6	0.5	-0.6	-0.8	-0.4	-1.2

Hub : Genes

NRXN2

Models

Trait associations