Best TWAS P=5.1e-19 · Best GWAS P=8.47e-19 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Prostate | LRPPRC | 0.16 | 0.10 | lasso | 3 | 0.05 | 1.8e-02 | -4.8 | 5.2 | 2.1e-07 | -0.13 | 0.03 | 0.69 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RP11-89K21.1 | 0.09 | 0.06 | lasso | 2 | 0.05 | 4.3e-07 | -8.9 | 8.9 | 5.1e-19 | -0.98 | 0.00 | 1.00 | TRUE |
| 3 | YFS | Blood | LRPPRC | 0.06 | 0.04 | bslmm | 548 | 0.04 | 1.4e-13 | -5.2 | 5.4 | 6.9e-08 | -0.12 | 0.00 | 0.99 | TRUE |