Best TWAS P=2.18e-07 · Best GWAS P=4.32e-06 conditioned to 0.846
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | MSH6 | 0.09 | 0.04 | lasso | 2 | 0.03 | 4.1e-03 | -4.5 | -5.2 | 2.2e-07 | 0.95 | 0 | 0.92 | FALSE |
| 2 | GTEx | Thyroid | MSH6 | 0.15 | 0.17 | enet | 12 | 0.16 | 3.5e-12 | -4.5 | -5.2 | 2.2e-07 | 0.90 | 0 | 0.96 | TRUE |