Hub : Genes

CDKAL1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.322 0.0410 0.0e+00 0.160 0.248 0.272 0.274 0.264 4.6e-19 5.6e-30 4.1e-33 2.0e-33 5.0e-32
2 GTEx Cells Transformed fibroblasts 0.138 0.0550 9.7e-03 0.000 NA -0.003 NA -0.004 2.9e-01 NA 5.7e-01 NA 9.5e-01
3 GTEx Skin Not Sun Exposed Suprapubic 0.133 0.0510 5.0e-03 -0.005 NA 0.004 NA 0.000 9.2e-01 NA 1.8e-01 NA 3.2e-01
4 GTEx Thyroid 0.105 0.0360 1.1e-03 0.071 NA 0.064 NA 0.076 4.3e-06 NA 1.1e-05 NA 1.9e-06
5 ROSMAP Brain Pre-frontal Cortex 0.111 0.0281 7.2e-06 0.078 0.044 0.056 0.063 0.076 2.9e-10 1.9e-06 1.0e-07 1.4e-08 5.3e-10
6 YFS Blood 0.128 0.0216 0.0e+00 0.073 0.078 0.097 0.093 0.090 7.3e-23 3.2e-24 3.7e-30 8.6e-29 7.3e-28
7 TCGA Brain Lower Grade Glioma 0.143 0.0486 3.0e-05 0.077 0.021 0.049 NA 0.067 3.9e-09 1.6e-03 3.0e-06 NA 4.2e-08
8 TCGA Thyroid Carcinoma 0.074 0.0310 3.3e-03 -0.002 0.016 -0.003 NA -0.003 5.5e-01 8.8e-03 9.7e-01 NA 8.9e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.6 0.9 2.5 -1.6 -1.1 -0.2 0.7 -1.4 -0.1 -1.1 0.1
Bipolar Disorder or Schizophrenia 0.5 1.2 3.6 -1.9 -1.4 -1.9 -0.4 0.3 0.2 0.6 -0.4
Depressed Affect (Nagel 2018) 0.6 1.2 5.3 -2.3 -0.2 -0.1 0.7 1.0 0.3 1.6 0.2
Depression (Nagel 2018) 1.2 1.8 5.7 -2.4 -2.0 -0.3 0.5 1.1 -0.1 1.8 0.5
Intelligence (Savage-Jansen 2018) 1.0 3.1 7.3 2.4 1.8 0.6 0.4 -2.2 0.4 -2.7 -1.8
Neuroticism (Nagel 2018) 1.5 3.5 7.9 -2.8 0.0 2.2 2.1 1.8 0.7 2.6 0.5
Schizophrenia (2018) 0.9 1.8 5.2 -1.2 -0.9 -2.3 -1.0 1.6 0.2 1.7 -0.6
Schizophrenia vs Biploar Disorder 1.7 2.2 5.9 -0.7 -2.1 -1.4 -0.6 1.7 -0.4 2.4 -1.2
Worry (Nagel 2018) 1.2 2.6 5.9 -2.3 -0.2 2.1 1.1 1.8 -0.5 2.4 0.7
Alzheimer’s Disease (in mother) 0.8 0.9 4.3 0.8 2.1 0.0 0.0 -1.0 -0.5 -1.0 0.1
Alzheimer’s Disease (in father) 1.3 1.4 5.3 0.4 0.3 -0.3 0.1 -1.9 0.7 -2.3 1.3
Alzheimer’s Disease (including proxy) 0.9 1.2 3.6 1.4 1.1 -0.6 -0.7 -1.5 -0.1 -1.9 0.4
Crohns Disease (2017) 3.2 6.9 18.8 3.3 -2.1 -1.1 -3.3 -1.6 -1.5 -2.1 -4.3
Irritable Bowel Disease (IBD) 2.9 6.8 21.5 3.5 -1.7 -0.4 -2.8 -1.3 -2.2 -1.7 -4.6
Ulcerative Colitis (UC) 1.4 2.6 9.9 2.3 -0.7 0.5 -0.8 -0.5 -2.0 -0.7 -3.1
Major Depression (MDD) 0.4 0.5 1.0 0.3 0.1 -0.8 0.9 -0.7 -0.7 -1.0 -0.4
Reaction Time 0.8 1.5 4.8 -2.2 -0.8 -0.7 0.3 1.5 0.3 1.9 0.4
Verbal and Numeric Reasoning (VNR) 1.0 2.5 7.0 2.2 1.8 0.4 0.1 -1.7 0.6 -2.6 -1.0
Breast Cancer 2.0 4.8 25.8 2.9 -0.2 -0.0 -5.1 -0.6 0.7 -1.6 -1.1
Ovarian Cancer 3.1 4.1 12.8 0.9 -0.8 0.1 -0.4 -3.5 -0.4 -3.6 -2.5
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 1.0 1.5 5.6 -0.3 0.4 0.3 0.5 -2.4 0.5 -2.3 -0.7
Bipolar Disorder (2011) 0.3 0.3 0.9 -0.3 -0.1 -0.5 -1.0 -0.3 0.8 -0.5 -0.1
Body Mass Index (BMI) (2010) 0.8 1.1 4.2 -1.1 0.6 0.1 0.5 -0.8 -1.5 -0.3 2.0
Coronary Artery Disease (CAD) 1.3 1.6 5.0 -1.5 -0.3 -0.2 2.2 -0.6 -2.2 0.3 -0.6
Crohns Disease (2012) 4.5 7.2 18.8 2.9 -2.2 -1.2 -3.1 -2.3 0.2 -3.2 -4.3
Mean Putamen Volume 1.2 1.3 5.8 0.4 0.4 2.4 2.0 -0.1 0.3 -0.0 -0.4
Fasting Glucose 1.4 1.7 5.1 -1.6 -0.3 0.3 2.3 -0.8 -2.0 -0.0 -1.2
HbA1C 3.6 4.0 11.2 0.6 2.2 3.3 2.6 2.4 0.1 1.8 0.2
HDL Cholesterol 0.2 0.3 1.1 -0.5 -0.5 -0.2 -1.0 -0.4 0.3 -0.4 0.0
LDL Cholesterol 0.2 0.4 1.1 0.7 0.6 -0.5 0.7 0.2 -0.3 0.2 1.0
Lupus 0.3 0.4 1.2 0.3 -0.3 -0.3 0.2 1.1 -0.8 0.7 -0.7
Neuroticism (2016) 1.2 1.7 6.1 -1.1 -0.2 -0.3 -0.7 2.3 0.4 2.5 0.5
Primary Biliary Cirrhosis 0.4 0.6 1.6 -0.9 1.2 1.2 0.2 0.5 0.3 0.5 0.1
Rheumatoid Arthritis 1.3 1.8 3.2 1.8 1.0 -1.8 -0.5 -1.6 -0.9 -1.8 -0.5
Schizophrenia (2014) 1.0 2.2 8.1 -1.7 -1.4 -2.9 -0.6 1.1 0.7 1.5 -0.7
Triglycerides 1.1 1.7 4.7 0.6 1.9 2.1 2.2 0.5 0.4 0.4 -0.7
Type 2 Diabetes (T2D) (2012) 1.4 1.6 7.2 0.1 0.3 0.6 2.7 -0.2 -0.8 0.6 -2.1
Ulcerative Colitis 1.3 1.9 6.0 2.0 -0.2 -0.2 -1.7 -0.4 -1.1 -0.7 -2.4
Blood Eosinophil Count 0.2 1.2 1.9 1.2 -0.9 -1.4 1.4 -1.3 -1.0 -0.9 -0.6
Blood Platelet Count 0.5 5.4 35.6 -1.1 1.2 1.0 6.0 -0.7 -1.2 -0.4 1.4
Blood Red Count 0.4 3.6 11.7 3.4 -1.2 1.3 1.0 -0.1 -0.1 -1.1 -3.4
Blood White Count 1.1 8.3 37.1 6.1 -0.6 -1.5 0.5 -1.9 -2.0 -3.0 -3.2
Heel T-Score 0.2 1.8 4.9 0.8 2.2 -1.1 -0.9 -1.3 0.9 -2.2 -0.0
BMI 0.5 3.0 11.1 -0.2 2.8 0.7 1.9 -0.4 -1.0 0.3 3.3
Height 0.1 2.2 10.6 -0.0 0.1 -1.1 -3.2 -0.7 2.2 -0.8 0.4
Waist Hip Ratio (WHR) 1.8 8.1 28.2 -2.3 1.4 2.5 5.3 1.4 -2.8 2.7 2.4
Systolic Blood Pressure 0.5 2.5 10.8 -0.0 0.3 1.1 3.3 0.5 -1.4 1.4 -1.8
Smoking Status 0.7 1.6 4.1 -0.9 0.5 1.8 1.0 1.7 -0.4 2.0 -0.3
Allergy or Eczema 1.6 4.2 8.1 2.8 -2.7 -2.3 -2.0 -1.4 -1.4 -1.8 -1.2
Cardiovascular Disease 1.0 3.4 13.9 -2.1 2.4 0.9 3.7 0.3 -0.3 1.3 -0.3
Hypothyroidism (self reported) 0.1 0.3 1.0 -0.6 -0.5 -1.0 -0.4 -0.3 -0.4 -0.0 0.5
Respiratory disease 0.5 1.0 3.0 -1.5 -0.9 -0.4 -0.3 0.3 -1.7 1.2 -0.9
Type 2 Diabetes (T2D) (2018) 4.8 8.9 43.3 -2.4 1.2 3.7 6.6 -0.6 -0.6 0.8 -2.4
Lung FEV1/FVC ratio 0.4 2.1 5.4 1.6 0.6 0.3 2.3 -1.7 -0.9 -1.7 -1.5
Lung FVC 0.2 0.9 2.1 1.3 0.3 -0.7 0.0 1.0 1.2 0.3 -1.5
Neuroticism 0.7 1.8 4.4 -2.0 0.4 2.1 1.9 0.4 -0.1 1.2 -0.4
Chronotype (morning person) 0.6 1.5 5.4 0.8 0.1 -2.0 -2.3 -0.2 1.0 -0.9 -0.0
Hair Pigment 0.7 19.2 92.7 0.0 4.5 5.2 9.6 -0.4 -2.3 0.1 3.0
Tanning 0.2 2.6 9.2 -2.0 -3.0 -0.4 -1.2 -0.9 -1.9 0.0 -1.1
Hand grip strength (left) 0.5 1.2 3.2 -1.4 -1.0 0.2 -1.7 0.5 1.8 0.6 -0.5
Number of treatments/medications taken 1.9 3.4 8.4 -1.5 2.0 2.8 2.9 1.1 -0.1 1.7 -0.6
Average weekly spirits intake 0.8 1.0 4.8 0.2 0.2 -0.3 0.2 -1.0 -2.2 -0.7 -1.1
Sensitivity / hurt feelings 0.7 1.2 3.2 1.8 1.2 0.8 1.5 0.2 -0.5 0.0 -1.2
Frequency of depressed mood in last 2 weeks 0.5 0.8 4.0 -0.5 -0.5 0.9 2.0 0.3 -0.5 0.5 -0.3
Hearing difficulty/problems: Yes 0.5 0.8 2.7 -0.5 0.6 0.5 -0.3 -1.6 -0.9 -1.1 -0.7
Relative age of first facial hair 1.4 2.9 12.1 -0.4 1.5 2.5 3.5 -0.8 -0.1 -1.1 0.6
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 2.4 0.8 -0.7 0.5 0.5 -0.0 -1.6 0.0 -0.6
Ever used hormone-replacement therapy (HRT) 4.2 5.3 15.9 -0.9 2.4 4.0 2.2 2.2 1.5 2.3 1.8
Ever had hysterectomy (womb removed) 3.3 3.7 8.1 1.7 2.8 2.7 1.1 1.6 2.7 0.6 0.6
Systolic blood pressure, automated reading 0.7 1.9 7.2 0.5 -0.9 -0.1 1.1 -0.3 -2.4 0.5 -2.7
Eye problems/disorders: Diabetes related eye disease 1.9 2.0 4.8 -1.8 -1.6 0.3 1.6 0.4 -0.8 1.5 -2.2
Angina 0.6 0.8 2.2 -0.3 1.5 -0.4 -0.2 1.2 0.9 1.2 0.5
Medication for hormone replacement therapy 2.0 2.2 5.7 -2.4 0.3 1.4 -0.9 1.9 -0.6 2.3 0.1
Vitamin and mineral supplements 0.2 0.3 0.9 -0.6 -0.1 -1.0 -0.2 -0.6 -0.2 -0.3 0.6
Supplements: Zinc 1.2 1.3 3.8 -0.2 -0.6 0.4 1.3 -2.0 -0.3 -2.0 -0.6
Medication: Co-codamol 0.7 0.8 4.5 -0.4 0.5 0.2 0.9 -0.6 -2.1 -0.5 -0.1
Medication: Metformin 2.4 3.4 11.9 -1.1 0.9 2.2 3.5 -1.3 -0.9 -0.5 -2.4
Diabetes (father) 4.3 5.4 25.9 -1.4 0.4 3.2 5.1 0.1 -1.5 1.4 -0.3
Diabetes (mother) 4.4 5.6 25.8 -1.5 1.6 1.9 5.1 1.6 -1.2 2.6 0.4
Severe depression (siblings) 2.1 2.3 7.4 -1.3 0.0 -1.3 0.9 -2.1 -2.7 -1.5 -0.2
Pack years adult smoking proportion 0.8 1.2 7.4 -2.7 -1.1 0.4 0.6 -0.4 0.4 0.2 -0.3
Impedance of leg (right) 0.5 2.3 11.9 0.5 -0.4 1.5 3.5 1.1 -0.3 1.1 -1.2
Leg fat-free mass (left) 0.6 3.1 11.3 -0.1 2.3 -0.2 -2.3 0.0 1.6 -0.3 3.4
Trunk fat percentage 0.9 3.6 8.6 -0.6 1.4 2.6 2.9 0.0 -1.3 0.9 2.9
Hand grip strength (right) 0.6 1.7 6.1 -1.2 -1.4 -0.6 -2.5 0.4 0.9 0.8 -1.5
Townsend deprivation index at recruitment 0.2 0.2 1.0 -0.2 -0.5 -0.6 -0.2 -0.1 -1.0 -0.1 0.3
Current tobacco smoking 0.6 0.9 2.2 0.1 -1.5 -0.3 -1.3 1.2 -0.1 1.0 -0.9
Average weekly fortified wine intake 0.9 1.0 2.9 0.3 1.7 -0.2 0.7 -1.2 0.9 -1.1 -1.0
Maternal smoking around birth 0.8 1.2 4.0 0.5 0.7 0.5 -0.0 2.0 -0.3 1.7 1.3
Fed-up feelings 0.2 0.4 1.3 -1.1 -0.4 -0.7 0.0 0.4 0.2 0.7 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.2 2.3 -1.5 -1.0 -0.5 -1.2 1.4 0.6 1.5 -0.2
Relative age voice broke 0.1 0.2 0.8 -0.3 -0.9 -0.0 -0.1 -0.4 -0.4 -0.2 -0.2
Taking other prescription medications 1.4 2.1 8.3 -1.1 0.5 1.2 2.9 1.3 -0.6 1.8 0.7
Age when periods started (menarche) 0.6 1.5 6.9 0.9 1.4 2.6 0.6 0.5 1.1 0.0 -0.6
Bilateral oophorectomy (both ovaries removed) 1.3 1.6 5.6 0.3 -0.3 0.4 1.0 2.3 0.3 2.4 0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 2.0 -0.6 -1.4 -0.9 -0.0 0.3 0.6 0.1 -0.1
Tinnitus: Yes, but not now, but have in the past 0.8 0.9 3.5 -1.9 -0.3 -0.3 0.1 0.1 -1.6 0.9 -0.4
Qualifications: CSEs or equivalent 0.7 0.9 3.1 -0.3 -1.3 -1.8 -1.1 0.7 -0.0 0.6 0.6
Serious illness, injury or assault to yourself 1.0 1.2 2.8 -0.2 -0.1 1.7 1.5 0.7 -0.9 0.9 1.6
High blood pressure 1.3 3.7 11.6 -0.3 3.2 2.4 3.4 0.6 -0.2 1.3 -0.5
Hayfever, allergic rhinitis or eczema 1.9 4.1 8.3 2.9 -2.7 -1.9 -2.1 -1.0 -1.2 -1.8 -1.8
Multivitamins +/- minerals 0.8 1.0 4.5 2.1 0.5 1.2 0.4 1.0 0.5 0.0 -0.3
Stomach or abdominal pain in last month 0.5 0.6 1.9 0.8 1.4 0.2 0.8 0.8 -0.1 0.4 1.0
Supplements: Glucosamine 4.2 5.5 14.7 3.3 2.5 1.7 -0.5 -2.6 1.5 -3.8 0.7
Diverticular disease/diverticulitis (self-reported) 1.2 1.4 4.7 -1.0 0.2 0.7 2.2 1.4 0.2 1.7 0.2
Medication: Atenolol 1.5 1.8 8.7 1.0 3.0 0.6 1.6 0.8 0.6 0.7 -0.6
Medication: Levothyroxine sodium 0.7 1.2 4.8 0.2 -1.3 -0.7 -0.1 -1.2 -2.2 -0.8 -0.6
Sitting height 0.4 2.8 9.3 1.4 1.6 -1.4 -3.0 1.3 2.0 0.3 1.2
Chronic bronchitis/emphysema (father) 1.2 1.4 4.6 -1.4 1.4 -0.5 -0.2 0.5 1.4 0.3 2.1
High blood pressure (mother) 1.2 1.7 5.2 -0.2 -1.4 -1.0 -0.0 -0.9 -2.2 -0.4 -2.3
Body mass index (BMI) 0.5 2.1 9.9 -0.3 1.8 1.4 0.8 0.5 -0.2 1.0 3.1
Impedance of leg (left) 0.4 2.1 8.4 0.2 -1.4 1.0 2.9 1.0 -0.4 1.2 -1.7
Leg predicted mass (left) 0.6 3.0 10.9 -0.1 2.2 -0.2 -2.4 0.1 1.6 -0.2 3.3
Trunk fat mass 0.7 3.1 12.3 -0.6 1.9 2.0 1.8 0.3 -0.4 0.9 3.5
Waist circumference 1.1 3.9 16.2 -1.2 1.8 2.0 1.8 0.7 -0.8 1.5 4.0
Number of incorrect matches in round 1.2 2.0 9.5 -0.1 0.9 1.3 -0.5 1.4 3.1 1.4 0.1
Past tobacco smoking 0.9 1.6 5.4 0.9 0.1 -2.3 -1.3 -0.0 1.2 -0.8 1.8
Alcohol usually taken with meals 0.7 1.2 5.9 0.0 2.4 0.4 -0.1 1.3 0.5 0.9 0.7
Nervous feelings 0.5 1.0 3.5 -1.1 0.2 1.4 1.9 0.7 -0.0 0.8 -0.1
Frequency of tenseness / restlessness in last 2 weeks 1.2 1.9 5.8 -0.2 0.8 2.4 1.9 1.2 1.4 0.8 0.8
Hearing difficulty/problems with background noise 0.4 0.6 1.3 -0.7 1.1 1.2 0.6 -0.7 -0.8 -0.1 0.3
Hair/balding pattern: Pattern 2 1.0 1.3 4.5 -1.7 -0.6 -2.1 -1.5 0.2 0.2 0.5 -0.1
Had menopause 1.3 1.6 7.1 -0.2 0.7 2.7 0.9 1.2 0.3 1.5 0.4
Had other major operations 1.2 1.5 3.9 -1.3 -0.2 0.8 -0.1 1.3 -1.5 2.0 1.2
Forced vital capacity (FVC) 0.5 1.9 4.4 1.7 0.9 -0.9 -1.7 1.8 2.1 0.5 -0.5
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 1.8 -0.0 -0.6 -1.2 -1.2 1.4 1.3 0.6 0.7
Ever unenthusiastic/disinterested for a whole week 1.0 1.2 3.0 -0.6 0.6 -1.7 -0.6 -1.7 -0.6 -1.6 0.0
Qualifications: None of the above 0.4 0.8 2.2 -1.4 -1.5 0.7 1.0 0.5 -0.3 0.9 -0.1
Financial difficulties in last 2 years 1.1 1.5 4.4 -0.3 0.5 0.1 -1.2 2.1 0.1 2.1 1.2
Mouth/teeth dental problems 1.4 2.2 8.8 -1.1 -0.3 -3.0 -1.6 -1.3 0.7 -1.4 0.9
Heart attack 0.5 0.7 2.1 0.1 1.1 0.6 1.4 -0.0 1.3 -0.1 -0.0
Allergy 0.8 1.8 4.8 -1.1 2.2 1.1 1.6 -0.0 1.6 0.3 1.2
Pain all over the body in last month 4.0 4.3 7.4 -1.1 1.6 2.5 2.3 2.6 -1.0 2.7 2.0
Diabetes (self-reported) 2.3 3.6 12.5 -1.5 0.8 2.2 3.5 -0.8 -0.7 0.3 -2.7
Hayfever/allergic rhinitis (self-reported) 1.2 1.5 5.6 -0.4 -0.1 -0.5 -0.0 1.3 1.9 1.1 2.4
Medication: Ramipril 1.9 2.4 8.9 0.2 1.9 2.3 3.0 -0.5 -0.2 -0.3 -0.8
Medication: Simvastatin 0.8 1.1 7.4 0.4 0.7 0.2 0.9 -0.2 -0.1 -0.1 -2.7
Fluid intelligence score 1.2 2.4 6.3 2.5 1.8 0.2 -0.1 -1.5 0.3 -2.4 -1.3
Illnesses of siblings 0.9 1.2 4.5 0.1 -1.3 0.4 -2.1 0.0 1.7 -0.4 0.4
Neuroticism score 0.6 1.2 3.7 -1.1 0.9 1.2 1.9 0.8 0.1 1.3 -0.4
Weight 0.5 2.5 12.3 -0.3 2.1 1.2 -0.5 0.5 0.6 0.7 3.5
Impedance of arm (right) 0.4 1.6 4.9 -0.2 -0.8 2.1 2.2 0.2 -1.6 0.4 -0.6
Arm fat percentage (right) 1.0 4.1 13.0 -0.8 1.6 2.6 2.4 0.2 -1.6 1.0 3.6
Trunk fat-free mass 0.8 4.4 11.9 0.5 2.4 -0.9 -3.5 0.5 2.8 -0.3 2.9
Hip circumference 0.4 1.9 12.2 -0.3 1.0 0.2 -0.9 0.1 0.8 0.4 3.5
Time employed in main current job 1.1 1.3 2.6 0.8 -1.6 -1.6 -0.6 -0.6 -1.5 -0.0 -1.3
Alcohol intake versus 10 years previously 0.3 0.4 1.3 -0.1 0.4 1.2 1.0 0.3 -0.7 0.3 0.4
Father’s age at death 0.4 0.5 1.2 -0.8 0.2 1.1 0.7 0.4 0.1 0.7 -0.9
Worrier / anxious feelings 0.3 0.5 1.4 0.3 -0.7 -0.5 0.4 1.0 -1.0 1.2 0.1
Frequency of tiredness / lethargy in last 2 weeks 0.9 1.5 4.2 -0.2 1.2 1.5 2.1 1.4 -0.1 1.1 0.9
Falls in the last year 1.7 2.3 4.8 -2.1 1.0 1.4 1.8 0.1 -1.5 0.8 2.2
Hair/balding pattern: Pattern 3 1.6 2.3 8.3 1.6 0.7 -0.7 1.3 -1.7 -2.9 -1.5 -0.3
Number of live births 0.7 0.9 3.0 -1.7 -0.1 1.2 0.1 0.7 -1.1 1.1 -0.4
Forced expiratory volume in 1-second (FEV1) 0.4 1.2 2.7 1.6 1.2 -1.1 -1.1 0.5 1.6 -0.6 -0.3
Pulse rate 0.3 0.6 1.7 -1.3 -0.8 -0.4 -0.2 -0.4 -1.3 0.4 -0.0
Happiness 0.7 0.9 2.4 0.4 0.5 -0.5 -1.0 -1.2 -1.0 -1.6 -0.5
Noisy workplace 0.5 0.7 1.2 -1.1 -0.9 0.8 1.0 -1.0 -0.6 -0.5 0.2
Qualifications: A levels/AS levels or equivalent 0.2 0.5 1.7 0.2 1.3 0.4 -0.1 -0.8 0.4 -0.9 0.9
Serious illness, injury or assault of a close relative in last 2 years 1.4 1.6 3.6 1.5 1.7 -1.9 -0.9 -0.9 0.1 -1.6 -0.3
Mouth/teeth dental problems: Dentures 0.8 1.3 5.8 0.9 -1.0 0.7 -0.4 -0.2 -1.5 0.0 -2.4
Asthma 0.2 0.5 0.9 -0.2 0.7 0.9 0.8 0.6 -0.8 0.8 -0.1
Medication: Ibuprofen (e.g. Nurofen) 1.9 2.4 5.6 -0.3 2.2 2.4 1.2 1.6 1.3 1.5 1.0
Medication: Cholesterol lowering 0.3 0.5 2.8 0.0 0.4 -0.6 0.5 -0.5 -0.2 -0.4 -1.7
Depression (self-reported) 0.2 0.3 0.5 0.7 0.7 0.4 0.6 0.7 0.2 0.4 0.4
Medication: Lansoprazole 1.2 1.4 2.7 -0.6 0.1 -1.5 -1.6 1.5 0.7 1.6 0.5
Prospective memory result 1.1 1.3 5.0 -2.2 -0.6 1.7 1.1 0.2 0.7 0.7 -0.2
Lung cancer (father) 1.2 1.4 3.5 -1.9 -1.3 -1.1 0.8 0.9 -0.3 1.4 1.1
Illnesses of mother 0.8 1.0 2.9 0.4 -0.4 -0.5 -1.0 -1.1 0.9 -1.7 1.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 2.8 0.7 0.2 -1.2 -1.1 -0.2 1.7 -1.0 -0.5
Pulse wave Arterial Stiffness index 0.5 0.5 1.6 1.2 0.1 -0.1 0.9 -0.1 -1.3 -0.3 -0.6
Impedance of arm (left) 0.4 1.7 6.2 -0.4 -0.6 1.7 2.5 0.3 -1.7 0.7 -0.8
Arm fat mass (right) 0.8 3.1 14.2 -0.7 2.0 1.9 1.3 0.1 -0.6 0.7 3.8
Trunk predicted mass 0.8 4.6 12.9 0.5 2.3 -1.0 -3.6 0.4 2.9 -0.4 2.9
Standing height 0.2 1.6 6.7 0.2 0.8 -0.5 -2.6 0.3 1.9 -0.3 1.2
Length of working week for main job 0.5 0.5 1.3 0.1 -0.8 -1.1 -1.1 -0.1 -0.4 0.3 -1.0
Exposure to tobacco smoke at home 1.2 1.3 4.7 -1.1 0.2 -1.2 -0.1 -2.2 0.5 -1.8 0.1
Breastfed as a baby 0.8 1.0 3.2 0.8 0.1 0.1 -0.9 -1.5 0.9 -1.8 0.2
Tense / ‘highly strung’ 0.8 1.3 4.7 -0.6 0.1 2.2 1.3 0.9 -0.2 1.1 1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 2.3 3.5 7.0 -2.1 1.2 1.4 2.6 1.9 0.7 2.6 1.5
Hair/balding pattern: Pattern 4 2.4 5.7 29.8 -0.9 -0.4 1.5 5.5 2.2 0.4 2.7 0.7
Birth weight of first child 1.5 2.6 4.6 1.0 -2.2 -1.3 -2.0 -1.7 0.6 -2.0 -1.6
Peak expiratory flow (PEF) 0.2 0.5 1.4 0.0 1.1 -1.2 -0.8 0.0 0.5 -0.4 -0.1
Pulse wave reflection index 0.6 0.7 2.9 0.9 -0.2 -0.1 0.2 -0.7 -1.7 -0.9 -0.5
Ever highly irritable/argumentative for 2 days 1.1 1.3 8.3 -2.9 -0.4 0.7 0.3 0.2 0.4 1.0 0.2
Loud music exposure frequency 0.5 0.5 1.5 -0.6 -0.4 -0.2 1.2 -1.1 -0.6 -0.7 -0.2
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 3.7 1.2 1.3 -0.3 -1.9 0.5 1.0 0.2 -0.1
Mouth/teeth dental problems: Bleeding gums 3.0 3.9 7.6 0.6 1.8 2.1 2.1 2.8 -0.8 2.8 1.6
Blood clot in the leg (DVT) 0.3 0.4 1.8 -0.2 -0.8 -0.5 -1.4 0.4 -0.2 0.4 0.1
Medication: Paracetamol 3.9 6.4 16.6 -1.8 1.1 0.1 3.3 3.5 -0.1 4.1 2.8
Headache pain in last month 0.2 0.4 1.5 -0.1 -0.1 -0.1 1.0 -0.5 -1.2 -0.3 -0.4
Medication for cholesterol, blood pressure or diabetes 0.8 1.4 4.4 -0.1 -1.6 -0.9 -0.6 1.2 -0.1 1.2 2.1
Glaucoma (self-reported) 0.6 0.7 1.8 -1.4 0.4 -0.2 1.1 0.1 -1.1 0.6 0.9
Gout (self-reported) 1.0 1.4 5.2 -2.3 -0.0 1.1 1.4 0.8 0.9 1.2 0.4
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 1.3 -0.8 -1.1 -1.1 0.2 -0.6 -0.9 -0.2 0.1
Medication: Amlodipine 1.7 2.4 5.6 0.7 2.4 1.5 0.9 1.4 2.4 1.0 -1.3
Medication: Ventolin 100micrograms inhaler 0.7 0.9 3.9 -0.9 0.8 -0.1 2.0 0.3 -1.0 0.6 0.4
Birth weight 1.5 3.2 15.3 0.6 -0.4 -0.9 -3.9 1.1 0.9 0.5 2.6
Chronic bronchitis/emphysema (mother) 1.8 2.1 5.3 -0.7 2.0 1.6 -0.6 0.8 2.3 0.4 1.8
High blood pressure (siblings) 1.0 1.5 2.9 -1.5 1.1 -1.4 1.7 -1.1 -1.2 -0.3 0.8
Forced vital capacity (FVC), Best measure 0.4 1.6 4.2 0.7 -0.3 -1.6 -2.0 0.9 2.0 -0.0 -0.4
Body fat percentage 1.0 4.1 9.7 -0.7 1.7 2.6 3.1 0.6 -1.2 1.4 3.0
Leg fat percentage (right) 1.1 3.9 9.2 -0.2 2.1 2.1 3.0 0.9 -0.8 1.6 3.0
Arm fat-free mass (right) 0.5 2.7 7.0 0.2 1.8 -0.6 -2.3 0.5 2.6 -0.0 2.4
Exposure to tobacco smoke outside home 0.4 0.6 2.4 -0.8 1.5 -0.2 1.0 -0.4 0.2 -0.2 -0.3
Comparative body size at age 10 0.4 1.2 2.9 -0.8 0.8 1.7 1.5 0.4 0.8 0.4 1.4
Number of full brothers 0.4 0.5 1.6 -0.1 0.3 -0.1 1.0 -1.2 -0.3 -1.0 -0.6
Worry too long after embarrassment 1.6 2.6 8.6 -0.8 0.0 2.2 2.9 1.5 0.9 1.8 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 1.4 1.8 3.4 -1.1 1.4 1.3 0.8 1.8 1.6 1.5 1.1
Wheeze or whistling in the chest in last year 1.2 2.2 7.0 -0.3 0.1 2.3 1.6 0.6 -2.6 1.3 -0.5
Number of children fathered 0.3 0.4 1.1 0.2 -0.7 -0.0 1.1 0.5 -0.7 0.8 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 2.0 0.4 0.2 1.4 0.7 -0.8 0.1 -1.0 0.3
Age at first live birth 0.6 1.1 2.8 0.3 1.0 -1.7 -0.3 -1.3 0.9 -1.5 0.1
Pulse wave peak to peak time 0.5 0.6 2.0 -0.8 -0.2 -0.1 -1.2 0.2 1.4 0.2 0.5
Health satisfaction 0.6 0.8 3.5 0.3 1.9 -0.1 0.2 0.6 -0.9 0.3 1.1
Shortness of breath walking on level ground 0.8 1.0 1.5 -0.5 1.2 0.9 1.1 1.0 1.1 1.2 0.9
Qualifications: College or University degree 0.3 1.0 4.3 -0.1 2.1 1.2 0.4 0.6 1.0 0.3 0.9
Eye problems/disorders: None of the above 0.9 1.1 3.5 0.9 -1.9 -0.3 -1.0 -0.7 1.2 -1.0 0.2
Mouth/teeth dental problems: Loose teeth 0.6 0.7 2.2 0.5 0.0 1.0 -0.2 -0.4 -1.4 -0.5 -1.5
Emphysema/chronic bronchitis 0.4 0.4 1.9 -0.4 -0.6 -1.4 -0.9 -0.0 -0.4 -0.2 -0.3
Medication for pain relief, constipation, heartburn 2.9 5.0 9.7 0.7 -3.1 -2.1 -3.1 -2.2 -0.7 -2.7 -1.7
Neck or shoulder pain in last month 1.8 2.5 7.5 -2.7 0.4 1.1 0.7 1.3 0.3 1.4 2.6
Medication: Blood pressure 1.3 2.3 8.4 0.4 2.4 2.9 1.2 -0.5 0.7 -0.6 -1.3
Angina (self-reported) 0.6 0.8 2.1 -0.0 1.2 -0.3 -0.3 1.4 0.9 1.4 0.4
Migraine (self-reported) 0.4 0.5 1.5 -0.3 1.2 -0.5 -0.8 0.3 0.3 -0.1 1.0
Medication: Ibuprofen 2.2 2.7 5.4 -1.0 2.3 2.2 1.0 1.5 1.5 1.5 1.6
Medication: Allopurinol 0.9 1.2 5.3 -2.3 -0.4 1.3 1.3 0.1 0.6 0.5 -0.0
Medication: Omeprazole 0.9 1.0 3.0 0.0 0.2 0.5 0.1 -1.7 -1.7 -1.4 -0.5
Medication: Seretide 50 evohaler 0.6 0.7 2.1 -0.3 0.3 -0.2 0.8 -0.9 -1.4 -0.6 -1.2
Mean time to correctly identify matches 0.6 1.1 3.3 -1.8 -0.9 -0.4 1.0 1.0 0.0 1.5 0.2
Heart disease (mother) 1.5 1.9 6.6 -1.4 -0.4 0.9 0.8 2.0 -0.7 2.6 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 1.3 1.1 0.8 0.5 0.3 1.1 -0.9 0.6 0.4
Whole body fat mass 0.9 3.6 13.3 -0.7 2.2 2.2 1.8 0.6 -0.3 1.2 3.6
Leg fat mass (right) 0.8 3.2 13.2 -0.6 2.2 1.6 1.5 0.6 -0.0 1.1 3.6
Arm predicted mass (right) 0.6 2.9 6.4 0.3 2.2 -0.8 -2.4 0.5 2.5 -0.1 2.3
Pulse rate, automated reading 0.6 2.0 7.6 -1.2 0.3 0.7 2.8 1.2 -0.5 1.7 1.2
Alcohol intake frequency. 0.3 0.7 3.5 -1.9 -0.7 0.1 0.7 0.1 -0.3 0.5 1.0
Comparative height size at age 10 0.1 0.7 2.0 0.7 -0.2 0.6 -0.6 -0.7 0.8 -0.9 1.4
Number of full sisters 0.2 0.2 0.6 0.4 0.6 -0.2 -0.8 0.3 0.6 -0.1 -0.2
Suffer from ‘nerves’ 0.9 1.4 6.6 -0.4 0.7 2.6 1.1 1.1 0.2 1.0 -0.9
Overall health rating 2.1 4.5 9.7 -2.2 1.3 0.9 2.9 2.0 -1.7 3.1 1.8
Chest pain or discomfort 0.3 0.4 2.5 -0.3 0.1 -0.5 1.6 -0.3 -0.7 0.2 -0.1
Had major operations 0.8 0.9 4.8 2.2 -0.4 0.9 -0.5 -0.3 -0.1 -0.6 -0.8
Age at last live birth 0.8 1.1 2.6 -1.6 1.0 0.1 0.6 -1.6 -0.3 -1.4 0.8
Family relationship satisfaction 1.1 1.4 3.1 -1.8 1.6 -0.6 -1.2 0.8 -0.3 1.0 1.5
Leg pain on walking 0.5 0.6 2.3 -1.0 1.5 0.5 0.3 -0.2 -0.2 0.1 1.0
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 2.9 -1.7 -0.5 -0.7 -0.3 -1.0 -0.6 -0.5 0.1
Commuting to job workplace: Car/motor vehicle 1.6 1.8 7.5 -0.5 -2.7 -0.6 -1.4 -1.0 -1.1 -0.6 -1.3
Illness, injury, bereavement, stress in last 2 years 1.1 1.4 5.8 -0.6 -2.4 0.5 0.3 -1.0 -1.3 -0.4 -1.3
Medication: Aspirin 1.4 1.8 6.1 0.5 2.5 2.3 1.2 0.3 1.2 0.2 -0.5
Supplements: Vitamin C 0.4 0.4 1.8 -1.3 0.1 1.1 0.1 -0.2 0.3 0.4 -0.4
Knee pain experienced in last month 0.5 0.8 2.1 -1.0 1.4 1.1 0.1 0.2 0.1 0.5 1.5
Hypertension (Self-reported) 1.2 3.4 10.2 -0.5 3.2 2.1 3.2 0.2 -0.5 0.9 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 2.3 -0.2 -0.2 0.1 0.1 -0.5 -1.5 0.0 -1.2
Illnesses of father: Heart disease 1.5 2.0 5.7 -0.1 1.1 0.7 -0.7 2.1 2.4 1.9 0.4
Illnesses of siblings: Diabetes 3.3 4.0 8.2 -1.2 2.4 2.3 2.9 2.1 -0.2 2.4 1.1
Smoking status: Previous 1.1 1.7 6.7 -0.9 0.7 2.6 1.7 0.1 -1.0 0.8 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 4.6 0.4 0.5 -1.0 -2.1 0.0 1.4 -0.7 1.1
Whole body fat-free mass 0.7 3.8 9.9 0.2 2.2 -0.8 -3.1 0.3 2.4 -0.3 3.0
Leg fat-free mass (right) 0.6 2.9 9.1 -0.2 1.7 -0.7 -3.0 -0.1 1.6 -0.4 2.9
Arm fat percentage (left) 1.0 3.8 11.2 -0.9 1.6 2.4 2.5 0.4 -1.5 1.2 3.4
Average weekly red wine intake 0.8 1.2 5.1 2.2 1.8 0.6 0.3 0.7 -0.6 0.2 -0.2
Handedness (chirality/laterality): Left-handed 1.9 2.2 6.1 -2.3 1.0 1.0 1.7 0.1 0.9 0.9 2.5
Mood swings 0.5 1.0 4.5 -2.1 -0.8 -0.5 0.7 0.7 0.4 1.1 -0.4
Loneliness, isolation 0.9 1.3 4.3 -0.1 2.1 1.1 1.2 1.0 0.8 0.8 1.0
Long-standing illness, disability or infirmity 0.6 0.9 3.0 0.1 0.1 0.1 1.7 0.8 -0.1 0.6 -1.7
Ever had bowel cancer screening 1.0 1.2 4.8 0.8 2.2 0.5 0.9 0.4 1.6 -0.2 -0.1
Diabetes diagnosed by doctor 2.8 4.6 14.7 -1.6 0.4 2.5 3.8 -0.9 -0.6 0.2 -3.5
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.2 2.8 -0.4 0.8 0.6 0.1 -1.7 -1.0 -1.6 1.3
Friendships satisfaction 0.6 0.8 4.0 0.0 2.0 0.7 0.7 0.1 0.8 -0.2 0.7
Qualifications: nursing, teaching 0.8 1.2 4.2 1.0 1.7 1.0 0.5 0.8 2.0 0.3 -0.1
Commuting to job workplace: Walk 0.6 0.6 1.3 -1.1 0.9 0.2 0.5 1.0 -0.2 1.2 0.4
Eye problems/disorders: Cataract 0.8 0.9 5.5 0.1 2.3 -0.8 -0.5 0.1 -0.5 -0.0 -0.5
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 1.8 1.3 0.7 1.4 0.3 -0.1 1.1 -0.2 -0.0
Medication for cholesterol 1.5 2.3 5.6 0.5 -1.1 -1.8 -2.0 -1.6 0.6 -2.4 1.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 1.1 -0.7 1.0 0.5 0.4 0.1 0.5 0.1 0.9
Back pain experienced in last month 0.5 0.7 2.1 -1.4 -0.3 -0.1 0.5 -0.5 -1.4 -0.1 1.0
Mineral and other dietary supplements 2.6 3.5 7.4 -1.6 -1.6 -2.7 -1.3 1.9 -1.6 2.7 -0.5
Breast cancer (self-reported) 1.1 1.3 3.5 -0.2 0.3 -0.1 1.4 -1.9 -0.9 -1.8 0.7
Asthma (self-reported) 0.2 0.4 0.8 -0.2 0.9 0.9 0.9 0.5 -0.7 0.6 -0.1
Osteoporosis (self-reported) 0.9 1.1 3.8 1.3 -0.7 -2.0 -1.3 0.0 -0.8 -0.4 -0.5
Osteoarthritis (self-reported) 0.1 0.1 0.5 -0.5 0.7 -0.0 0.1 0.5 0.3 0.4 -0.1
Medication: Aspirin 1.2 1.6 5.0 0.4 2.2 1.9 1.0 0.9 1.2 0.7 -0.5
Medication: Gliclazide 2.5 2.8 13.3 0.1 -0.6 1.5 1.3 -1.5 -0.9 -1.2 -3.6
Illnesses of father: None of the above (group 1) 0.8 1.0 3.5 0.7 -1.5 -1.0 0.5 -0.1 -1.9 -0.2 -0.5
Smoking status: Current 0.6 0.9 1.8 0.3 -1.2 -0.2 -1.2 1.3 0.0 1.2 -1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 3.0 1.7 0.8 -0.7 -1.0 -0.1 0.5 -0.9 -1.0
Whole body water mass 0.7 3.7 9.7 0.3 2.1 -0.8 -3.1 0.3 2.4 -0.3 3.0
Leg predicted mass (right) 0.6 3.0 8.7 -0.2 1.7 -0.6 -2.9 -0.0 1.7 -0.4 2.9
Arm fat mass (left) 0.6 2.6 11.8 -0.4 1.9 1.8 1.1 0.2 -0.7 0.6 3.4
Number of self-reported non-cancer illnesses 1.1 2.0 5.1 -0.8 1.3 2.0 2.3 1.1 -0.5 1.7 -0.5
Average weekly champagne plus white wine intake 0.3 0.4 1.3 0.2 0.4 1.0 0.1 -0.5 1.1 -0.8 0.4
Miserableness 0.6 1.0 3.3 -1.1 1.0 0.9 1.8 0.6 0.4 0.9 0.0
Guilty feelings 2.0 2.9 6.4 -2.4 0.3 0.5 2.0 1.9 1.6 2.5 0.7
Wears glasses or contact lenses 1.4 1.6 8.4 -1.0 2.9 0.9 0.7 0.8 0.2 0.9 0.2
Ever taken oral contraceptive pill 0.5 0.5 2.3 -0.6 1.5 0.1 0.1 0.4 0.3 0.4 1.1
Hearing aid user 2.7 3.1 5.9 -0.3 -2.1 -1.9 1.2 -2.4 -2.3 -1.8 -0.9
Mother’s age at death 3.7 4.6 12.5 -0.7 -2.0 -1.6 -0.1 -3.5 -2.5 -2.8 -1.8
Financial situation satisfaction 0.5 0.7 3.1 -0.6 1.8 0.6 0.9 -0.3 -0.0 -0.1 0.8
Tinnitus: Yes, now most or all of the time 0.7 0.8 3.1 1.8 1.6 -0.1 0.8 -0.2 0.0 -0.7 0.1
Commuting to job workplace: Public transport 1.4 1.7 10.7 0.4 3.3 0.5 0.4 -0.4 0.2 -0.9 1.1
Eye problems/disorders: Glaucoma 0.4 0.4 1.3 -1.1 -0.1 -0.3 0.8 -0.2 -1.1 0.4 -0.0
Medication: Blood pressure 0.9 1.7 6.7 0.8 1.4 1.2 2.6 0.5 -0.5 1.0 -1.3
Pain type(s) experienced in last month: Hip pain 0.6 0.8 5.1 -0.8 0.1 -0.2 -0.6 0.5 0.2 0.3 2.3
Supplements: Fish oil (including cod liver oil) 1.5 2.0 7.0 1.3 1.1 2.7 1.1 -1.2 0.5 -1.7 0.4
High cholesterol (Self-reported) 0.2 0.3 0.8 -0.3 0.9 0.3 0.5 0.3 0.7 0.6 -0.4
Medication: Bendroflumethiazide 0.9 1.4 5.3 -0.8 2.3 1.9 0.9 0.0 0.2 0.3 -0.5
Medication: Paracetamol 2.9 4.4 13.7 -1.5 0.0 -0.2 2.5 2.9 -0.8 3.7 2.0
Medication: Lisinopril 0.7 0.9 1.6 1.1 -0.1 1.2 1.0 0.9 1.1 0.5 -1.3
Medication: Atorvastatin 1.0 1.3 5.4 0.1 1.4 1.2 0.1 0.7 2.3 0.6 0.8
Illnesses of father: High blood pressure 0.8 1.0 3.0 0.6 0.1 1.4 -0.2 -1.2 1.1 -1.7 -0.5
Alcohol drinker status: Never 0.3 0.4 1.7 1.3 0.8 -0.5 -0.4 0.2 0.3 -0.5 -0.2
Ever smoked 0.6 1.0 1.7 -1.3 -0.9 1.2 0.9 0.2 -0.7 1.0 -1.3
Basal metabolic rate 0.6 3.1 10.5 0.1 2.2 -0.4 -2.5 0.2 1.9 -0.2 3.2
Leg fat percentage (left) 0.8 3.0 7.2 -0.1 1.7 1.7 2.4 1.1 -0.8 1.8 2.7
Arm fat-free mass (left) 0.5 2.4 6.1 0.1 1.6 -0.4 -2.5 0.3 2.1 -0.1 2.5
Number of operations (self-reported) 0.4 0.6 1.7 -0.1 -0.2 1.3 0.1 -0.5 -1.1 -0.2 -1.3
Average weekly beer plus cider intake 0.3 0.5 2.0 1.4 0.7 -0.7 0.4 0.6 0.1 0.4 0.3
Irritability 0.4 0.8 3.2 0.5 0.4 1.8 0.8 -0.3 0.6 -0.2 -1.1
Risk taking 0.8 1.1 3.6 0.5 -0.9 0.5 -0.3 -1.5 -1.9 -1.2 -0.3
Ever had prostate specific antigen (PSA) test 0.7 0.8 2.4 0.5 0.1 1.4 -0.7 0.2 -1.6 0.4 -0.8
Fractured/broken bones in last 5 years 2.0 2.6 10.9 0.1 0.6 3.3 2.1 1.3 -0.5 1.4 -0.9
Age started oral contraceptive pill 0.8 1.0 3.3 -0.8 -0.7 0.9 1.8 -0.6 -1.1 0.2 -1.2
Diastolic blood pressure, automated reading 0.4 1.1 4.1 -0.1 -0.6 -0.2 1.3 0.5 -2.0 1.1 -1.3
Ever depressed for a whole week 1.8 2.3 8.0 -1.6 0.5 -0.5 0.8 -1.9 -2.8 -1.2 -1.2
Unable to work because of sickness or disability 1.3 1.7 5.5 -2.3 -2.2 0.1 1.0 0.5 -0.8 0.9 -0.1
Commuting to job workplace: Cycle 0.6 0.7 4.3 2.1 -0.7 -0.6 -0.6 0.4 0.3 0.2 -0.2
Myopia 0.3 0.4 1.0 0.9 0.7 0.5 0.7 -0.2 -1.0 -0.5 0.3
Vascular/heart problems diagnosed by doctor 1.7 4.6 14.3 0.3 -3.5 -2.8 -3.8 -0.8 -0.2 -1.3 0.1
Cholesterol lowering medication 0.7 1.0 2.1 -0.0 1.1 1.4 0.9 1.0 0.3 1.3 -1.2
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 3.1 -0.4 0.1 0.7 -0.1 -1.2 -1.8 -0.6 -0.0
Pain experienced in last month 1.8 3.0 6.7 1.7 -2.1 -1.9 -1.8 -0.8 1.3 -1.1 -2.6
Supplements: Calcium 0.6 0.7 2.4 0.9 -0.5 1.5 0.2 -0.2 0.3 -0.4 -1.3
Basal cell carcinoma (self-reported) 0.5 0.6 1.5 -0.6 1.2 0.4 0.5 -0.2 1.0 -0.0 1.1
Heart attack/myocardial infarction (self-reported) 0.4 0.6 1.7 0.4 1.1 0.4 1.3 0.2 1.1 0.0 -0.0
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 0.9 -0.0 -0.5 -0.2 -1.0 0.1 -0.4 0.2 0.3
Heart disease (siblings) 0.6 0.7 2.1 1.5 0.5 -0.4 0.6 -0.3 -1.5 -0.3 -0.4
Alcohol drinker status: Previous 1.2 1.4 3.1 -1.5 1.1 1.5 1.3 0.5 -0.4 0.7 1.8
Pack years of smoking 1.0 1.5 7.2 -2.7 -1.4 0.3 1.0 -1.0 -0.3 -0.2 -0.8
Impedance of whole body 0.4 2.3 9.8 -0.2 -1.0 1.5 3.1 0.4 -1.4 0.8 -1.5
Leg fat mass (left) 0.7 2.8 12.2 -0.7 1.9 1.4 1.2 0.7 -0.1 1.3 3.5
Arm predicted mass (left) 0.5 2.4 5.9 0.2 1.7 -0.5 -2.4 0.1 2.2 -0.3 2.4