Best TWAS P=3.03e-08 · Best GWAS P=2.6e-16 conditioned to 6.75e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ARAP1 | 0.12 | 0.00 | lasso | 6 | 0.00 | 1.7e-01 | -5.2 | 5.4 | 5.9e-08 | -0.75 | 0.09 | 0.17 | FALSE |
| 2 | GTEx | Liver | CLPB | 0.25 | 0.05 | lasso | 5 | 0.02 | 7.1e-02 | -6.1 | -5.5 | 3.0e-08 | 0.55 | 0.04 | 0.08 | TRUE |
| 3 | YFS | Blood | STARD10 | 0.33 | 0.28 | bslmm | 322 | 0.37 | 4.8e-129 | 1.7 | 5.3 | 1.5e-07 | -0.52 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | ARAP1 | 0.26 | 0.01 | enet | 14 | 0.04 | 3.9e-05 | 2.9 | -5.2 | 1.8e-07 | 0.56 | 0.01 | 0.96 | TRUE |