Best TWAS P=1.5e-07 · Best GWAS P=1.42e-08 conditioned to 0.0272
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | ZZEF1 | 0.07 | 0.06 | lasso | 5 | 0.06 | 8.1e-08 | 4.9 | 5.2 | 1.7e-07 | 0.93 | 0.02 | 0.98 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ANKFY1 | 0.05 | 0.03 | enet | 11 | 0.02 | 1.2e-03 | 5.4 | 5.3 | 1.5e-07 | 0.88 | 0.01 | 0.98 | TRUE |