TWAS hub - PPM1N

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1110	0.0380	1.1e-03	0.092	NA	0.075	NA	0.083	6.0e-08	NA	1.0e-06	NA	2.4e-07
2	GTEx	Cells EBV-transformed lymphocytes	0.2160	0.0710	1.9e-03	0.195	NA	0.086	NA	0.115	5.7e-07	NA	9.3e-04	NA	1.4e-04
3	GTEx	Cells Transformed fibroblasts	0.3120	0.0520	3.4e-10	0.307	NA	0.278	NA	0.299	2.1e-23	NA	5.5e-21	NA	9.0e-23
4	GTEx	Colon Transverse	0.1460	0.0530	3.3e-03	0.057	NA	0.020	NA	0.046	1.0e-03	NA	3.9e-02	NA	3.1e-03
5	GTEx	Esophagus Muscularis	0.1090	0.0400	1.3e-03	0.163	NA	0.142	NA	0.052	3.8e-10	NA	6.1e-09	NA	4.2e-04
6	GTEx	Lung	0.1790	0.0486	7.1e-06	0.145	NA	0.125	NA	0.129	3.2e-11	NA	8.0e-10	NA	4.5e-10
7	GTEx	Nerve Tibial	0.1699	0.0486	8.7e-05	0.102	NA	0.072	NA	0.076	1.1e-07	NA	7.8e-06	NA	4.9e-06
8	GTEx	Whole Blood	0.0630	0.0260	7.2e-03	0.004	NA	0.033	NA	0.019	1.1e-01	NA	5.2e-04	NA	6.6e-03
9	TCGA	Breast Invasive Carcinoma	0.0251	0.0112	5.0e-05	0.021	0.023	0.025	NA	0.028	2.5e-05	1.4e-05	6.1e-06	NA	1.9e-06
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0928	0.0357	2.2e-09	0.107	0.096	0.087	NA	0.105	5.2e-12	6.2e-11	4.8e-10	NA	7.1e-12
11	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0850	0.0390	2.9e-04	0.095	0.073	0.091	NA	0.097	4.2e-06	5.7e-05	6.7e-06	NA	3.4e-06
12	TCGA	Brain Lower Grade Glioma	0.0852	0.0328	1.2e-07	0.090	0.074	0.078	NA	0.080	2.0e-10	9.5e-09	3.4e-09	NA	1.9e-09
13	TCGA	Pancreatic Adenocarcinoma	0.1680	0.0760	2.2e-04	0.004	0.057	0.070	NA	0.045	2.1e-01	2.1e-03	7.2e-04	NA	5.9e-03
14	TCGA	Pheochromocytoma and Paraganglioma	0.1030	0.0560	8.5e-03	0.078	0.011	0.000	NA	0.041	5.2e-04	1.1e-01	3.2e-01	NA	9.4e-03
15	TCGA	Prostate Adenocarcinoma	0.0557	0.0260	1.1e-04	0.048	0.039	0.031	NA	0.033	9.2e-06	6.0e-05	3.1e-04	NA	2.1e-04
16	TCGA	Soft Tissue Sarcoma	0.0990	0.0490	8.6e-04	0.072	0.032	0.024	NA	0.058	4.6e-05	5.3e-03	1.4e-02	NA	2.4e-04
17	TCGA	Stomach Adenocarcinoma	0.0600	0.0270	1.5e-04	0.048	0.046	0.050	NA	0.051	2.2e-04	2.9e-04	1.5e-04	NA	1.3e-04
18	TCGA	Thyroid Carcinoma	0.0380	0.0200	9.4e-04	0.026	0.026	0.027	NA	0.025	1.4e-03	1.4e-03	1.0e-03	NA	1.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Medication for cholesterol, blood pressure or diabetes	7.6	12.5	22.1	-3.5	-4.0	-3.6	-4.1	-3.6	-3.5	-3.6	-4.7	-3.3	-3.7	-3.4	-3.7	-1.9	-2.7	-2.6	-4.1	-3.7	-3.0
Had menopause	7.5	9.4	15.4	-2.8	-3.6	-3.9	-2.9	-2.9	-2.9	-3.9	-3.0	-3.0	-3.3	-2.6	-3.6	-2.9	-3.1	-1.2	-3.3	-3.5	-1.2
Medication: Ramipril	7.5	9.6	12.0	3.3	3.1	3.0	3.0	3.4	3.5	3.0	2.9	3.1	3.3	3.4	3.2	2.6	1.4	2.9	3.4	3.4	3.3
Type 2 Diabetes (T2D) (2018)	6.4	11.9	37.5	3.4	3.9	3.4	4.3	3.8	3.2	3.5	6.1	3.4	3.1	3.2	3.3	2.5	2.6	1.6	3.1	3.2	2.0
Medication: Metformin	6.4	9.1	28.7	3.0	3.0	2.7	3.5	3.2	2.9	2.8	5.4	3.2	2.6	3.1	2.6	3.2	2.3	1.9	2.3	2.6	2.3
Medication for hormone replacement therapy	6.3	7.1	10.7	-2.9	-2.7	-3.0	-2.5	-2.7	-2.9	-3.0	-1.8	-2.7	-2.8	-3.3	-2.9	-2.5	-1.7	-2.7	-2.8	-2.9	-1.6
Mother’s age at death	6.1	7.7	11.4	-3.0	-2.5	-3.0	-2.3	-2.9	-3.2	-3.0	-1.4	-3.4	-3.0	-2.9	-2.9	-3.0	-1.7	-2.6	-2.7	-3.0	-2.3
Vascular/heart problems diagnosed by doctor	5.0	13.7	17.7	-4.1	-3.9	-3.6	-4.1	-4.2	-4.1	-3.6	-3.8	-3.8	-3.9	-4.1	-3.7	-2.3	-1.4	-3.1	-4.0	-3.9	-3.7
Chronotype (morning person)	4.7	10.9	28.8	-3.3	-3.4	-3.1	-3.9	-3.4	-3.4	-3.2	-5.4	-3.4	-3.2	-3.4	-3.0	-2.0	-2.6	-2.7	-3.1	-3.1	-2.7
Diabetes diagnosed by doctor	4.7	7.7	21.8	2.8	2.8	2.6	3.3	3.1	2.8	2.7	4.7	3.2	2.4	2.8	2.4	3.1	1.8	1.7	1.8	2.4	2.3
Deep venous thrombosis (DVT) (self-reported)	4.7	6.0	9.5	2.8	2.9	2.5	3.1	3.0	2.5	2.5	2.7	2.6	2.6	2.2	2.8	2.0	1.8	1.0	2.4	2.6	0.8
Medication: Simvastatin	4.6	6.8	11.2	2.8	2.4	2.6	2.3	2.8	3.0	2.6	3.3	2.4	2.6	3.3	2.7	1.3	0.9	2.4	3.0	2.9	2.4
Medication: Blood pressure	4.6	8.1	13.9	2.8	3.4	3.1	3.3	2.9	2.7	3.1	3.7	2.5	3.1	2.5	3.2	0.8	2.2	1.5	3.7	3.1	1.9
Eye problems/disorders: Diabetes related eye disease	4.5	5.0	7.1	1.9	2.5	2.3	2.7	2.2	2.1	2.3	2.6	2.4	2.2	2.1	2.1	2.6	1.8	1.8	1.5	2.2	2.4
Blood Platelet Count	4.3	50.1	231.0	-6.6	-7.0	-7.5	-6.6	-6.2	-6.0	-7.6	-15.2	-6.5	-6.7	-6.4	-7.2	-4.9	-6.6	-2.8	-6.6	-6.8	-0.6
Lung FEV1/FVC ratio	4.3	21.6	25.9	4.8	4.7	5.0	4.7	4.6	4.9	5.0	4.2	5.1	5.0	4.8	4.8	4.0	3.7	3.7	5.1	4.9	4.2
Medication: Omeprazole	4.3	5.1	7.1	2.4	2.4	2.4	2.3	2.4	2.7	2.5	2.0	2.1	2.2	2.3	2.3	2.3	1.2	1.9	2.6	2.4	2.0
Cardiovascular Disease	4.2	14.0	17.5	4.0	4.2	4.0	4.1	4.1	4.0	4.0	3.6	3.7	4.1	3.9	4.1	2.3	1.7	3.1	4.2	4.1	3.3
Supplements: Glucosamine	4.1	5.3	8.4	-2.3	-2.3	-2.3	-2.6	-2.4	-2.3	-2.3	-1.4	-2.4	-2.4	-2.5	-2.2	-2.0	-1.9	-2.5	-2.2	-2.3	-2.9
Medication: Amlodipine	4.1	5.8	8.3	2.6	2.5	2.6	2.5	2.7	2.6	2.6	2.9	2.5	2.6	2.5	2.6	1.2	1.5	1.7	2.5	2.6	1.6
Blood clot in the leg (DVT)	4.0	5.2	7.7	2.6	2.6	2.4	2.8	2.8	2.3	2.4	2.4	2.4	2.5	2.1	2.6	1.7	1.8	1.0	2.3	2.5	0.6
High blood pressure	3.9	10.7	13.8	3.6	3.7	3.5	3.6	3.7	3.6	3.5	3.0	3.4	3.6	3.4	3.6	1.9	1.6	2.4	3.7	3.6	2.7
Knee pain experienced in last month	3.9	6.1	12.1	-2.5	-2.6	-2.4	-2.5	-2.5	-2.7	-2.3	-0.2	-2.2	-2.8	-2.8	-2.6	-1.4	-0.1	-2.9	-2.9	-2.8	-3.5
Cholesterol lowering medication	3.9	5.8	10.3	2.6	2.2	2.3	2.0	2.6	2.8	2.3	2.1	2.4	2.5	2.9	2.5	1.2	0.3	3.2	2.7	2.6	2.5
Prospective memory result	3.8	4.6	6.8	2.5	2.0	2.3	1.7	2.6	2.4	2.3	1.7	2.6	2.4	2.2	2.4	2.1	1.3	1.5	2.4	2.4	1.5
Time employed in main current job	3.4	3.9	6.0	2.2	1.9	2.1	1.5	2.0	2.1	2.1	0.9	2.0	2.4	2.2	2.3	1.5	0.9	2.1	2.4	2.4	1.4
Heel T-Score	3.3	26.6	51.6	5.4	4.6	4.8	3.0	5.5	5.7	4.7	0.1	4.1	5.9	6.7	5.6	2.1	0.0	7.1	7.2	6.1	6.2
Ever used hormone-replacement therapy (HRT)	3.3	4.2	7.3	-1.9	-2.6	-2.7	-2.0	-1.9	-1.9	-2.7	-1.0	-1.8	-2.3	-1.9	-2.6	-1.7	-1.5	-1.2	-2.4	-2.5	-0.7
Hypertension (Self-reported)	3.2	8.9	11.8	3.2	3.3	3.1	3.2	3.3	3.2	3.1	3.1	3.0	3.3	3.0	3.3	1.5	1.5	2.0	3.4	3.3	2.4
Eye problems/disorders: Cataract	3.2	3.7	5.8	-2.1	-2.4	-1.9	-2.4	-2.1	-2.1	-1.9	-1.6	-1.1	-2.0	-2.2	-2.2	-0.1	0.6	-1.9	-2.2	-2.3	-1.5
Eye problems/disorders: Glaucoma	3.2	3.8	10.8	1.6	1.4	2.0	1.6	1.7	1.9	2.1	2.2	2.4	1.7	1.7	1.5	3.1	3.3	1.4	1.2	1.5	1.5
Pain type(s) experienced in last month: Hip pain	3.2	4.0	6.2	-1.8	-2.2	-2.5	-1.5	-1.8	-1.9	-2.4	0.5	-1.9	-2.5	-1.9	-2.4	-2.1	-1.1	-2.2	-2.1	-2.5	-1.7
Body Mass Index (BMI) (2010)	3.0	4.1	6.2	2.2	2.0	2.2	1.8	2.1	2.1	2.2	1.2	2.2	2.3	2.0	2.3	1.9	1.5	1.5	2.5	2.3	1.4
Diabetes (self-reported)	3.0	4.7	15.1	2.2	2.1	2.0	2.7	2.5	2.1	2.0	3.9	2.5	1.7	2.1	1.8	2.5	1.0	1.3	1.2	1.8	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	3.0	4.5	8.8	-2.2	-1.9	-1.9	-1.8	-2.3	-2.3	-1.9	-0.6	-2.2	-2.4	-2.4	-2.1	-1.9	-1.1	-2.4	-2.4	-2.2	-3.0
High cholesterol (Self-reported)	2.9	5.2	10.8	2.0	2.5	2.2	2.5	2.0	2.3	2.1	2.8	1.9	2.3	2.4	2.2	1.3	0.5	3.3	2.1	2.3	3.1
Crohns Disease (2017)	2.7	5.8	12.1	2.0	2.5	2.1	2.6	2.1	2.1	2.1	3.5	2.5	2.4	2.0	2.1	3.0	1.8	2.4	1.8	2.2	3.3
Illness, injury, bereavement, stress in last 2 years	2.7	3.3	4.8	1.7	1.8	2.0	1.1	2.1	2.0	2.0	0.9	1.8	2.0	1.9	1.9	1.9	1.8	1.5	2.2	2.1	1.7
Medication: Aspirin	2.7	3.5	6.7	2.0	1.9	2.0	1.8	2.0	2.0	2.0	2.6	2.2	2.1	1.7	2.1	1.3	1.8	0.9	1.8	2.0	0.9
Heel bone mineral density (BMD) T-score, automated (left)	2.5	5.7	16.4	2.0	2.1	2.0	1.5	2.3	2.4	2.0	0.1	1.7	2.5	3.0	2.2	1.2	0.0	4.0	3.0	2.6	4.0
Hearing difficulty/problems with background noise	2.5	3.9	6.6	-1.9	-2.0	-2.1	-2.3	-1.7	-2.0	-2.1	-2.1	-2.6	-1.9	-1.7	-1.8	-2.3	-2.6	-1.2	-1.3	-1.7	-1.5
Medication: Blood pressure	2.5	4.7	7.1	2.4	2.2	2.2	2.2	2.7	2.5	2.2	1.2	2.2	2.4	2.5	2.3	1.5	0.1	2.2	2.4	2.4	2.2
Severe depression (siblings)	2.4	2.6	4.9	-1.7	-1.7	-1.4	-1.0	-1.7	-1.8	-1.4	0.1	-1.3	-1.9	-2.1	-1.8	-1.5	1.1	-1.5	-1.8	-2.0	-2.2
Tinnitus: Yes, but not now, but have in the past	2.4	2.6	4.3	-1.6	-1.6	-1.7	-1.1	-1.7	-1.9	-1.6	-1.3	-1.2	-1.8	-1.7	-1.8	-0.5	0.1	-1.8	-1.9	-1.9	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	2.4	5.5	12.5	2.2	2.4	2.3	1.8	2.4	2.4	2.2	0.4	1.6	2.5	2.9	2.5	1.0	-0.3	3.5	2.9	2.7	3.2
Medication for pain relief, constipation, heartburn	2.4	4.2	6.7	-2.5	-1.9	-2.3	-1.5	-2.5	-2.4	-2.3	-1.1	-2.2	-2.3	-2.2	-2.3	-1.2	-1.7	-1.1	-2.6	-2.3	-0.9
Medication: Atorvastatin	2.4	3.0	11.0	1.4	2.0	1.4	2.3	1.4	1.5	1.4	3.3	1.4	1.6	1.4	1.4	0.6	0.3	2.2	1.4	1.5	2.3
Fasting Glucose	2.3	2.7	5.6	1.7	1.5	1.8	1.7	1.5	1.7	1.9	2.4	2.2	1.5	1.4	1.5	1.8	1.8	1.1	1.3	1.4	0.8
Waist Hip Ratio (WHR)	2.3	10.5	15.8	3.5	3.4	3.1	4.0	3.9	3.6	3.1	2.8	3.5	3.3	3.2	3.2	3.2	1.6	1.9	2.9	3.3	3.7
Financial difficulties in last 2 years	2.3	3.1	8.8	-1.6	-1.9	-1.8	-2.0	-1.6	-1.5	-1.8	-1.4	-1.8	-1.9	-1.4	-1.6	-1.2	-3.0	-1.6	-1.8	-1.6	-1.3
Mineral and other dietary supplements	2.3	3.2	8.3	1.4	1.5	1.6	2.0	1.6	1.7	1.6	1.7	1.9	1.6	1.7	1.4	1.7	1.8	2.3	1.4	1.5	2.9
Medication: Omeprazole (e.g. Zanprol)	2.3	2.8	4.9	1.7	1.5	1.8	1.4	1.6	2.0	1.9	1.3	1.7	1.6	1.6	1.6	2.2	1.0	1.3	1.9	1.7	1.5
Number of self-reported non-cancer illnesses	2.2	3.8	5.6	2.2	2.1	1.9	2.4	2.4	2.3	2.0	1.8	2.0	1.9	2.0	1.9	1.7	0.7	1.3	2.1	2.0	2.1
Primary Biliary Cirrhosis	2.1	3.0	4.7	-1.7	-1.9	-2.0	-2.2	-1.5	-1.9	-2.0	-1.5	-1.9	-1.7	-1.3	-1.7	-2.0	-1.4	-1.3	-1.4	-1.7	-1.6
Medication: Aspirin	2.1	2.8	7.2	1.7	1.6	1.7	1.6	1.7	1.6	1.7	2.7	2.0	1.8	1.4	1.7	1.0	1.8	0.8	1.6	1.7	0.7
Friendships satisfaction	2.1	2.6	5.0	-1.6	-2.1	-1.7	-2.2	-1.6	-1.5	-1.7	-1.5	-1.5	-1.8	-1.3	-1.8	-0.9	-1.6	-0.5	-1.8	-1.7	-1.5
Systolic Blood Pressure	2.0	10.3	16.6	3.2	3.6	3.0	3.7	3.3	3.4	2.9	3.1	2.9	3.5	3.4	3.2	1.1	0.6	3.8	3.5	3.4	4.1
Age started oral contraceptive pill	2.0	2.5	7.1	-1.4	-1.9	-2.0	-1.7	-1.2	-1.2	-2.0	-0.2	-1.6	-1.7	-0.7	-1.8	-1.6	-2.7	0.6	-1.8	-1.7	0.1
Osteoarthritis (self-reported)	1.9	2.5	5.7	-1.2	-2.1	-2.0	-1.7	-1.0	-1.3	-1.9	-1.2	-1.5	-1.9	-0.9	-1.9	-2.4	-0.5	-1.2	-1.3	-1.8	-1.5
Medication: Lisinopril	1.9	2.4	4.9	1.7	2.1	1.6	2.2	1.7	1.5	1.6	2.0	1.2	1.6	1.2	1.8	-0.3	-0.4	0.6	1.9	1.8	0.5
Chronic bronchitis/emphysema (father)	1.8	2.1	4.7	-1.4	-1.4	-1.4	-1.6	-1.4	-1.4	-1.4	-0.3	-1.8	-1.4	-1.2	-1.2	-2.2	-1.0	-1.6	-1.0	-1.3	-2.0
Diabetes (father)	1.7	2.1	3.8	1.6	1.9	1.7	2.0	1.9	1.5	1.7	1.2	1.4	1.4	1.2	1.7	1.2	0.5	0.1	1.3	1.5	0.2
Pulse rate	1.7	2.9	4.9	1.9	1.9	1.8	1.9	2.0	1.8	1.9	2.1	1.3	1.6	1.8	1.9	1.1	0.6	0.2	2.2	1.9	0.8
Medication: Cholesterol lowering	1.7	2.7	10.0	1.5	1.7	1.3	2.2	1.5	1.6	1.3	3.2	1.3	1.3	1.7	1.3	0.5	1.1	1.6	1.6	1.4	2.0
Glaucoma (self-reported)	1.7	2.0	8.2	1.0	0.8	1.1	1.2	1.0	1.3	1.2	1.6	2.0	1.0	1.2	0.7	2.9	2.3	1.4	0.2	0.7	1.3
Risk taking	1.7	2.5	4.7	-1.7	-1.0	-1.7	-0.3	-1.7	-2.1	-1.7	-0.1	-1.6	-1.7	-2.2	-1.7	-1.5	-0.5	-1.8	-1.8	-1.9	-1.2
Lung FVC	1.6	8.2	12.7	-3.1	-3.4	-3.0	-3.6	-3.6	-3.2	-2.9	-1.6	-2.3	-3.0	-3.2	-3.2	-1.3	0.4	-2.0	-3.4	-3.3	-3.1
Alcohol intake versus 10 years previously	1.6	2.4	4.7	1.9	1.8	1.7	1.8	1.8	1.6	1.7	0.9	1.4	1.8	1.4	1.9	-0.2	1.6	0.4	2.2	1.7	-0.2
Loud music exposure frequency	1.6	1.8	3.5	1.7	1.1	1.2	1.1	1.6	1.7	1.2	0.8	1.4	1.2	1.9	1.3	1.1	-0.3	1.3	1.5	1.4	1.2
Comparative body size at age 10	1.6	4.3	7.4	-1.9	-2.4	-2.3	-2.5	-2.0	-1.9	-2.3	-2.7	-2.3	-2.1	-1.6	-2.2	-2.3	-2.4	-0.4	-1.6	-2.0	-0.8
Schizophrenia vs Biploar Disorder	1.5	2.0	5.6	-2.2	0.0	-2.4	-2.3	-2.3	-2.0	-2.4	-2.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HbA1C	1.5	1.7	4.5	-0.2	1.9	1.7	-0.3	0.2	-0.1	1.4	1.3	-0.2	2.1	-0.0	2.1	-0.5	-1.1	1.1	2.0	2.1	0.4
Shortness of breath walking on level ground	1.5	1.8	3.9	1.7	1.6	1.4	2.0	1.7	1.4	1.3	1.0	1.2	1.4	1.3	1.6	-0.1	-0.4	0.1	1.6	1.5	0.4
Heart disease (siblings)	1.5	1.8	3.1	1.8	1.1	1.4	1.4	1.7	1.7	1.5	1.3	1.5	1.3	1.6	1.3	1.0	0.9	0.9	1.4	1.3	0.7
Depressed Affect (Nagel 2018)	1.4	2.8	4.0	-1.8	-1.8	-1.9	-2.0	-1.8	-1.8	-1.9	-1.0	-1.8	-1.6	-1.6	-1.7	-1.9	-1.7	-0.9	-1.7	-1.7	-1.1
Irritable Bowel Disease (IBD)	1.4	3.3	10.2	1.6	1.9	1.7	2.0	1.6	1.5	1.7	3.2	1.9	1.9	1.4	1.7	1.8	1.6	1.5	1.4	1.7	1.8
Ovarian Cancer	1.4	1.8	2.9	1.5	1.5	1.6	1.3	1.5	1.6	1.6	0.3	1.1	1.3	1.6	1.7	1.2	-0.4	0.3	1.6	1.7	0.7
Father’s age at death	1.4	1.8	3.0	-1.6	-1.1	-1.3	-1.0	-1.6	-1.6	-1.3	-0.9	-1.7	-1.4	-1.6	-1.4	-1.7	-0.4	-0.9	-1.4	-1.4	-1.0
Illnesses of father: Heart disease	1.4	2.0	6.4	1.3	1.4	1.0	1.4	1.3	1.4	1.0	1.7	0.9	1.2	1.8	1.2	0.7	-0.6	2.5	1.4	1.3	2.0
Irritability	1.4	2.4	8.4	-1.2	-1.7	-1.0	-2.5	-1.3	-1.4	-1.0	-2.9	-1.3	-1.1	-1.3	-0.9	-1.2	-0.5	-1.7	-0.7	-1.0	-2.6
Alzheimer’s Disease (including proxy)	1.3	1.9	9.4	1.1	0.3	0.6	-0.3	0.6	1.3	0.6	-2.1	1.0	1.1	1.8	0.9	1.3	-1.0	3.1	1.4	1.1	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	3.9	-1.2	-1.6	-1.3	-1.4	-1.2	-1.2	-1.3	-0.9	-1.1	-1.4	-1.3	-1.4	-1.3	-0.3	-1.5	-1.4	-1.4	-2.0
Chronic bronchitis/emphysema (mother)	1.3	1.5	3.0	-1.6	-1.2	-1.1	-1.6	-1.7	-1.4	-1.1	-1.1	-1.0	-1.1	-1.5	-1.3	0.1	-0.4	-1.0	-1.4	-1.2	-0.4
Ever depressed for a whole week	1.3	1.6	4.8	1.2	1.0	1.3	1.4	1.3	1.2	1.3	0.8	1.6	1.0	1.3	1.0	2.2	1.6	1.1	0.6	0.9	0.6
Relative age of first facial hair	1.2	2.4	4.9	-1.5	-1.7	-1.5	-1.9	-1.6	-1.6	-1.4	-1.1	-1.5	-1.8	-1.4	-1.6	-0.6	-0.5	-1.6	-1.7	-1.7	-2.2
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	2.4	-1.3	-1.0	-1.4	-0.5	-1.4	-1.4	-1.4	0.1	-1.3	-1.4	-1.2	-1.4	-1.0	-0.5	-1.0	-1.6	-1.4	-0.8
Wheeze or whistling in the chest in last year	1.2	2.2	6.3	-0.5	-1.2	-1.4	-0.4	-0.6	-0.9	-1.4	-1.0	-1.7	-1.7	-1.1	-1.2	-2.2	-2.0	-2.5	-1.0	-1.3	-2.3
Health satisfaction	1.2	1.6	3.7	1.7	1.1	1.2	1.6	1.6	1.5	1.2	1.9	1.4	1.1	1.4	1.2	1.1	0.7	0.1	1.2	1.2	0.2
Emphysema/chronic bronchitis	1.2	1.4	5.6	-0.8	-0.9	-1.1	-0.3	-1.0	-0.9	-1.1	0.2	-0.7	-1.4	-1.2	-1.2	-1.1	0.1	-2.4	-1.0	-1.4	-1.9
Commuting to job workplace: Car/motor vehicle	1.2	1.3	3.8	-1.0	-1.1	-1.3	-0.7	-1.0	-1.1	-1.3	0.3	-1.7	-1.3	-0.9	-1.1	-1.6	-2.0	-0.8	-0.8	-1.0	-0.3
Medication: Gliclazide	1.2	1.3	10.7	0.8	1.1	0.6	1.7	1.1	0.8	0.7	3.3	0.8	0.6	1.0	0.6	1.0	0.1	0.7	0.4	0.7	1.1
Major Depression (MDD)	1.1	1.3	2.3	1.1	1.4	1.5	0.9	1.2	1.3	1.5	-0.7	1.2	1.2	1.2	1.3	1.3	-0.6	0.8	0.7	1.3	1.2
Number of treatments/medications taken	1.1	2.0	4.6	1.6	1.7	1.5	1.6	1.5	1.5	1.5	1.7	1.1	1.6	1.3	1.7	0.1	0.8	0.1	2.1	1.7	0.3
Systolic blood pressure, automated reading	1.1	3.3	9.4	1.7	1.7	1.3	1.9	1.6	1.9	1.3	1.5	1.9	2.0	1.9	1.5	0.8	0.3	3.1	1.7	1.7	2.9
Hair/balding pattern: Pattern 2	1.1	1.5	4.1	-1.3	-1.0	-1.0	-1.5	-1.1	-1.3	-1.0	-2.0	-1.3	-1.1	-1.3	-0.9	-0.8	-0.6	-1.5	-0.9	-1.0	-1.4
Length of working week for main job	1.1	1.2	2.4	-1.2	-1.1	-0.8	-1.3	-1.2	-1.3	-0.8	-1.6	-0.9	-0.9	-1.2	-0.8	-1.0	-0.3	-1.3	-1.2	-0.9	-1.4
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	3.9	0.8	1.4	1.6	1.1	0.8	0.9	1.6	1.1	1.1	1.3	0.8	1.4	1.3	2.0	0.7	1.1	1.2	0.1
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	3.0	1.6	1.3	1.3	1.6	1.5	1.5	1.3	1.7	0.8	1.0	1.6	1.3	-0.3	-0.8	1.7	1.4	1.3	0.6
Average weekly champagne plus white wine intake	1.1	1.5	5.2	-1.1	-1.3	-1.2	-1.4	-1.3	-1.0	-1.2	-2.3	-1.0	-1.2	-1.2	-1.2	0.1	-1.4	-0.6	-1.3	-1.2	-0.5
Supplements: Fish oil (including cod liver oil)	1.1	1.5	3.1	-1.2	-1.2	-1.2	-1.8	-1.4	-1.4	-1.2	-0.8	-1.1	-1.0	-1.3	-1.0	-0.4	-0.5	-1.3	-1.2	-1.1	-1.7
Alcohol drinker status: Never	1.1	1.3	5.3	-0.6	-0.9	-1.2	-0.3	-0.7	-0.6	-1.1	-1.4	-0.9	-1.0	-0.8	-1.1	-2.3	-2.3	0.1	-1.2	-1.1	-0.1
Reaction Time	1.0	2.0	5.3	1.4	1.8	1.3	2.3	1.7	1.4	1.3	2.3	1.1	1.2	1.3	1.3	1.1	-0.2	0.4	1.0	1.3	1.3
Forced vital capacity (FVC)	1.0	3.7	8.8	-2.3	-1.9	-1.5	-3.0	-2.7	-2.2	-1.6	-1.9	-1.8	-1.7	-2.2	-1.7	-0.6	0.6	-1.3	-2.0	-1.8	-2.3
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	4.7	0.9	1.1	1.4	1.1	0.8	0.9	1.4	0.4	1.4	0.9	0.8	1.0	2.2	1.4	1.1	0.4	0.9	0.4
Illnesses of father: None of the above (group 1)	1.0	1.2	6.9	-0.3	-0.9	-0.3	-1.0	-0.5	-0.8	-0.3	-1.5	-0.6	-0.6	-1.0	-0.3	-1.1	0.7	-2.4	-0.3	-0.5	-2.6
Smoking status: Current	1.0	1.6	9.7	-0.7	-0.4	-0.5	-0.5	-0.9	-1.2	-0.5	0.7	-0.8	-0.7	-1.6	-0.4	-1.0	0.5	-2.9	-1.0	-0.7	-3.1
Alcohol drinker status: Previous	1.0	1.1	2.7	-1.0	-1.2	-0.8	-1.3	-0.9	-1.0	-0.7	-1.0	-0.9	-1.1	-1.3	-0.9	-0.1	-0.5	-1.6	-1.0	-1.0	-1.6
HDL Cholesterol	0.9	1.5	2.8	1.2	0.9	1.2	0.8	1.0	1.4	1.2	0.2	1.7	1.5	1.3	1.2	1.6	0.7	1.6	1.0	1.2	1.1
Sensitivity / hurt feelings	0.9	1.5	6.2	-0.8	-1.5	-1.0	-2.3	-0.8	-1.1	-1.0	-1.5	-1.1	-0.8	-0.6	-0.7	-1.8	-0.3	-0.7	-0.5	-0.8	-2.5
Hair/balding pattern: Pattern 3	0.9	1.3	3.7	1.0	1.1	0.7	1.7	0.9	1.2	0.7	1.7	1.2	0.9	0.9	0.7	0.7	0.2	1.6	0.7	0.8	1.9
Mean time to correctly identify matches	0.9	1.6	7.3	1.1	1.4	0.9	2.0	1.3	1.2	1.0	2.7	1.2	1.0	1.2	0.9	1.1	-0.3	0.9	0.6	0.9	1.4
Suffer from ‘nerves’	0.9	1.4	2.5	1.4	1.2	1.5	1.1	1.6	1.4	1.5	0.6	1.2	1.2	1.2	1.4	0.7	0.3	0.6	1.3	1.3	-0.2
Loneliness, isolation	0.9	1.2	2.6	-0.7	-0.6	-1.2	-0.2	-0.8	-1.1	-1.2	0.5	-0.9	-1.1	-1.2	-0.9	-1.6	-1.6	-1.5	-1.2	-1.1	-1.4
Miserableness	0.9	1.6	3.5	-1.2	-1.4	-1.0	-1.6	-1.1	-1.2	-1.0	-1.9	-1.2	-1.2	-1.3	-1.1	-1.1	-0.4	-1.4	-0.9	-1.2	-1.6
Guilty feelings	0.9	1.4	4.6	-1.3	-1.5	-1.1	-2.0	-1.1	-1.1	-1.1	-2.2	-0.8	-1.1	-0.9	-1.2	0.8	-0.5	-0.1	-1.3	-1.0	-0.2
Medication: Paracetamol	0.9	1.5	2.9	1.7	0.8	1.4	0.1	1.7	1.3	1.4	-1.1	1.2	1.3	1.2	1.6	0.3	0.4	-0.3	1.6	1.5	-1.1
Number of operations (self-reported)	0.9	1.3	2.6	-1.2	-1.1	-1.1	-0.9	-1.2	-1.3	-1.1	-0.7	-1.4	-1.3	-1.5	-1.2	-0.9	-0.9	-1.6	-1.0	-1.2	-0.9
Crohns Disease (2012)	0.8	1.4	2.7	0.9	1.3	0.9	1.6	0.9	1.0	0.9	1.5	1.3	1.0	0.7	0.7	1.6	1.3	1.4	0.6	0.8	1.6
Diabetes (mother)	0.8	1.1	5.9	1.0	0.9	1.0	1.2	0.9	0.7	1.0	2.4	0.7	0.6	0.5	0.9	-0.1	1.1	-0.7	0.8	0.7	-1.3
Current tobacco smoking	0.8	1.4	8.4	-0.5	-0.1	-0.3	-0.2	-0.7	-1.0	-0.3	1.1	-0.6	-0.6	-1.4	-0.2	-0.9	0.5	-2.9	-0.7	-0.5	-2.9
Mouth/teeth dental problems: Dentures	0.8	1.3	5.8	-0.7	-0.5	-0.8	-0.4	-0.9	-1.0	-0.8	1.5	-1.0	-1.0	-1.2	-0.7	-1.6	-0.8	-1.8	-1.0	-0.9	-2.4
Hair/balding pattern: Pattern 4	0.8	2.0	7.5	1.3	1.1	0.9	1.0	1.3	1.5	0.9	0.5	1.6	1.4	1.7	0.9	1.7	0.9	2.1	1.1	1.2	2.7
Forced vital capacity (FVC), Best measure	0.8	3.1	8.1	-2.1	-1.8	-1.4	-2.9	-2.5	-2.0	-1.4	-1.7	-1.5	-1.5	-2.0	-1.5	-0.2	0.5	-1.0	-2.0	-1.6	-1.9
Overall health rating	0.8	1.8	6.8	1.6	1.3	1.2	1.9	1.5	1.5	1.2	2.6	1.2	1.0	1.2	1.2	1.0	-0.1	-0.3	1.2	1.2	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.8	0.9	1.2	1.2	0.8	1.0	0.9	1.2	0.3	0.8	1.3	0.8	1.4	0.0	0.7	0.5	1.2	1.3	-0.1
Asthma (self-reported)	0.8	1.6	4.6	-0.8	-1.2	-1.4	-0.9	-0.7	-0.9	-1.3	-0.8	-1.3	-1.5	-1.1	-1.2	-0.7	-2.1	-2.0	-1.2	-1.2	-1.5
Osteoporosis (self-reported)	0.8	1.0	2.5	1.2	0.9	1.0	1.3	1.0	1.1	1.1	0.7	1.1	0.9	0.9	0.9	0.1	1.6	-0.4	0.9	0.8	-0.7
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.0	-0.8	-1.3	-1.2	-1.3	-0.8	-0.8	-1.2	-1.4	-1.1	-1.1	-0.6	-1.1	-0.4	-0.3	-0.2	-0.9	-1.0	-0.2
Ever had prostate specific antigen (PSA) test	0.8	1.0	2.4	1.6	0.6	0.7	0.7	1.4	1.5	0.7	-0.4	0.9	0.8	1.4	0.9	0.3	-1.1	0.8	1.2	1.0	0.7
Breast Cancer	0.7	1.6	2.2	1.4	1.5	1.3	1.4	1.3	1.3	1.3	1.4	1.3	1.5	1.3	1.5	0.6	0.6	0.5	1.3	1.5	1.1
Allergy or Eczema	0.7	1.9	5.7	-0.8	-1.2	-1.2	-1.0	-1.0	-1.0	-1.2	-1.8	-1.4	-1.4	-1.2	-1.0	-1.2	-1.8	-2.2	-0.9	-1.1	-2.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.8	1.3	1.1	0.9	1.7	1.1	1.0	0.9	1.5	0.9	0.8	0.7	1.0	0.2	0.4	-0.5	0.9	0.8	-0.0
High blood pressure (mother)	0.7	0.9	2.1	1.2	1.1	1.0	0.9	1.1	1.0	1.0	-0.1	0.3	0.9	1.0	1.2	-0.5	-1.2	0.5	1.5	1.2	-0.2
Had other major operations	0.7	0.9	1.8	-0.7	-0.9	-1.1	-0.3	-0.8	-0.9	-1.1	-1.1	-0.7	-1.1	-1.0	-1.1	-0.4	-0.9	-1.0	-1.3	-1.2	-0.4
Number of live births	0.7	1.0	1.8	-0.9	-1.4	-0.9	-1.0	-1.1	-0.8	-0.9	-1.3	-0.8	-1.1	-1.1	-1.1	-1.0	-0.3	-0.8	-1.1	-1.2	-1.0
Illnesses of siblings: Diabetes	0.7	0.8	4.8	0.9	0.8	0.6	1.3	1.1	0.9	0.6	2.2	1.1	0.7	0.9	0.6	0.5	0.2	0.6	0.4	0.6	0.7
Ever had bowel cancer screening	0.7	0.8	4.5	-0.9	-0.4	-0.4	0.0	-0.8	-0.7	-0.4	-0.4	0.0	-0.6	-1.1	-0.9	1.6	2.1	-0.5	-0.9	-0.9	0.4
Medication: Bendroflumethiazide	0.7	1.1	4.5	0.7	1.3	1.0	1.0	1.0	0.6	0.9	2.1	0.7	1.1	0.8	1.1	0.7	0.3	1.1	1.3	1.1	0.7
Fractured/broken bones in last 5 years	0.7	0.9	5.6	-0.4	-0.5	-0.5	-0.1	-0.6	-0.7	-0.5	-0.3	-0.5	-0.8	-1.1	-0.5	-0.6	-0.3	-2.4	-1.2	-0.8	-2.2
Neuroticism (Nagel 2018)	0.6	1.5	5.7	-1.1	-1.5	-0.9	-2.4	-1.1	-1.1	-1.0	-2.3	-1.1	-0.8	-0.9	-0.8	-1.1	-1.1	-0.4	-0.8	-0.7	-1.4
Alzheimer’s Disease (in father)	0.6	0.6	4.0	0.6	0.1	0.4	-0.4	0.4	0.9	0.4	-0.8	0.4	0.5	1.1	0.4	0.9	-0.7	2.0	0.7	0.6	0.8
Age at First Birth	0.6	0.8	2.5	-1.0	-1.2	-0.9	-1.6	-0.9	-1.0	-0.9	-0.7	-0.9	-0.9	-0.8	-1.0	-0.3	-0.5	-0.6	-0.8	-0.9	-0.9
Mean Putamen Volume	0.6	0.6	2.0	-0.7	-1.1	-0.9	-1.4	-0.8	-0.7	-0.9	-0.6	-0.5	-0.8	-0.4	-0.9	0.0	-0.0	-0.1	-0.9	-0.9	-1.0
Angina	0.6	0.7	3.9	1.0	0.2	0.3	0.7	1.1	1.3	0.3	1.1	0.9	0.4	1.1	0.3	0.5	-0.2	0.6	0.6	0.5	2.0
Hip circumference	0.6	2.5	4.7	-1.4	-1.7	-1.5	-1.5	-1.6	-1.4	-1.5	-0.2	-1.9	-1.8	-1.6	-1.6	-2.2	-1.8	-1.7	-1.3	-1.6	-1.5
Asthma	0.6	1.3	4.8	-0.6	-0.9	-1.1	-0.7	-0.5	-0.7	-1.1	-0.9	-1.1	-1.2	-0.9	-0.9	-0.5	-2.2	-1.8	-1.0	-1.0	-1.3
Depression (self-reported)	0.6	0.7	2.6	-0.7	-0.6	-0.7	-0.3	-0.7	-0.9	-0.6	0.4	-1.0	-0.9	-1.0	-0.7	-1.6	-0.2	-1.3	-0.8	-0.8	-1.0
Illnesses of mother	0.6	0.7	5.8	0.2	0.3	0.5	0.5	0.5	0.3	0.5	1.8	0.9	0.4	0.2	0.3	1.3	2.4	-0.5	0.1	0.2	0.1
Birth weight	0.6	1.4	3.0	-0.8	-1.0	-1.3	-0.5	-0.8	-1.0	-1.3	-0.6	-1.2	-1.4	-1.2	-1.2	-1.3	-1.7	-1.2	-1.3	-1.3	-1.1
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.7	-1.0	-0.7	-1.0	-0.3	-1.1	-0.7	-1.0	0.1	-0.7	-1.0	-0.9	-1.0	0.0	-1.1	-0.1	-1.3	-1.0	0.3
Mood swings	0.6	1.2	2.4	-1.1	-1.3	-1.1	-1.6	-1.0	-1.2	-1.1	-0.4	-1.0	-1.0	-0.9	-1.0	-1.3	-0.9	-0.7	-1.1	-1.0	-1.3
Commuting to job workplace: Public transport	0.6	0.7	4.3	0.1	0.2	0.6	-0.5	-0.1	-0.0	0.6	-2.1	0.5	0.5	-0.3	0.6	0.2	1.2	-1.1	0.1	0.4	-1.7
Unable to work because of sickness or disability	0.6	0.7	2.7	-0.6	-0.5	-0.9	0.0	-0.6	-0.6	-0.9	1.5	-0.9	-0.8	-0.9	-0.7	-1.7	-1.2	-0.9	-0.4	-0.7	-0.2
Supplements: Calcium	0.6	0.7	3.2	-0.2	-0.8	-0.9	-0.7	-0.5	-0.5	-0.9	-0.7	-0.7	-0.8	-0.2	-0.7	-1.4	-0.9	-0.6	-0.6	-0.8	-1.8
Alzheimer’s Disease (in mother)	0.5	0.6	2.5	0.6	0.5	0.4	0.1	0.3	0.7	0.4	-1.1	0.7	0.9	0.7	0.7	0.4	-0.3	1.3	1.0	0.8	1.6
Lupus	0.5	0.8	5.4	0.7	0.8	0.7	1.2	1.0	0.7	0.7	2.3	0.8	0.4	0.7	0.4	0.8	0.2	1.0	-0.0	0.4	0.5
Blood Red Count	0.5	4.9	42.1	1.4	1.8	1.6	2.3	1.5	1.4	1.7	6.5	1.9	1.6	1.4	1.4	0.9	2.7	1.4	1.1	1.4	1.3
Hand grip strength (left)	0.5	1.2	5.2	0.7	0.4	0.3	-0.2	0.7	1.0	0.2	-0.4	0.1	0.9	1.6	0.7	-0.6	-0.9	2.3	2.0	1.0	2.0
Ever had hysterectomy (womb removed)	0.5	0.6	0.9	-0.9	-0.8	-0.8	-0.6	-1.0	-0.9	-0.8	-0.1	-0.8	-0.8	-1.0	-0.9	-0.6	-0.8	-0.2	-1.0	-0.9	-0.3
Pack years adult smoking proportion	0.5	0.8	3.1	0.5	1.1	0.9	1.5	0.5	0.4	0.9	1.8	0.5	0.5	-0.3	0.7	-0.0	1.3	-1.4	0.4	0.5	-0.4
Maternal smoking around birth	0.5	0.8	2.2	-1.1	-0.8	-0.9	-0.8	-1.1	-1.1	-0.9	0.1	-0.8	-0.7	-1.5	-0.8	-0.7	-0.1	-1.1	-0.9	-0.9	-0.3
Qualifications: CSEs or equivalent	0.5	0.7	5.7	0.3	0.2	0.6	-0.1	0.3	-0.1	0.6	-0.2	-0.4	0.1	-0.1	0.6	-0.4	0.5	-2.0	0.6	0.4	-2.4
Hayfever, allergic rhinitis or eczema	0.5	1.0	4.4	-0.3	-0.5	-0.8	-0.4	-0.5	-0.5	-0.8	-1.2	-1.1	-0.9	-0.8	-0.6	-0.8	-1.4	-2.1	-0.4	-0.7	-1.8
Allergy	0.5	1.2	7.2	0.2	0.4	0.7	0.1	0.3	0.4	0.7	1.2	0.9	1.0	0.9	0.5	0.6	1.1	2.7	0.5	0.7	2.3
Happiness	0.5	0.6	1.1	0.9	0.9	1.0	0.7	0.8	0.7	1.0	0.9	0.4	0.7	0.6	1.1	-0.2	-0.0	-0.2	0.8	0.9	-1.0
Pulse wave reflection index	0.5	0.6	1.7	-0.7	-1.0	-0.9	-1.0	-0.9	-0.7	-0.9	-0.8	-0.8	-0.8	-0.5	-0.9	-1.3	-0.5	0.1	-0.6	-0.8	-0.2
Eye problems/disorders: None of the above	0.5	0.6	3.6	-0.6	0.0	-0.5	0.0	-0.6	-0.7	-0.6	-0.5	-1.2	-0.5	-0.5	-0.3	-1.9	-1.7	-0.1	-0.1	-0.3	-0.1
Medication: Allopurinol	0.5	0.7	2.0	-0.9	-0.9	-0.6	-0.9	-0.7	-0.7	-0.6	-1.4	-0.4	-0.7	-1.2	-0.8	0.1	0.5	-1.2	-0.8	-0.8	-0.3
Family relationship satisfaction	0.5	0.6	4.0	0.9	0.3	0.6	0.1	0.9	0.5	0.6	0.4	0.3	0.3	0.8	0.8	-0.5	-0.4	-0.8	0.5	0.7	-2.0
Leg pain on walking	0.5	0.7	2.2	-0.5	-0.9	-0.8	-0.7	-0.4	-0.8	-0.8	-0.7	-0.2	-0.7	-0.9	-0.8	-0.2	0.4	-1.5	-0.9	-0.9	-1.3
Average weekly red wine intake	0.5	0.7	1.5	-1.0	-0.7	-0.7	-1.0	-0.9	-0.8	-0.7	-1.2	-0.6	-0.8	-0.7	-0.8	0.5	-1.2	-0.4	-1.2	-0.7	-0.0
Long-standing illness, disability or infirmity	0.5	0.8	6.4	0.8	1.0	0.6	1.5	0.9	0.6	0.6	2.5	0.5	0.4	0.5	0.7	0.0	0.1	-0.9	0.7	0.6	-0.5
Financial situation satisfaction	0.5	0.6	1.3	-0.6	-0.9	-0.7	-0.9	-0.5	-0.7	-0.7	0.3	-0.6	-0.9	-0.5	-0.7	-0.3	-1.1	-1.1	-0.9	-0.8	-1.1
LDL Cholesterol	0.4	0.7	5.7	0.1	-0.1	-0.2	-0.6	-0.3	0.5	-0.2	0.3	0.4	0.5	0.9	0.1	0.3	-0.7	2.4	0.6	0.3	1.8
BMI	0.4	2.2	19.2	1.1	1.6	0.9	2.8	1.2	0.8	0.9	4.4	0.9	0.8	0.5	0.8	-0.5	0.8	-0.2	1.0	0.7	0.7
Smoking Status	0.4	0.9	4.2	-0.5	-0.8	-0.8	-1.0	-0.6	-0.8	-0.8	-0.5	-0.7	-0.6	-1.3	-0.6	-1.1	0.2	-2.0	-0.5	-0.7	-1.8
Medication: Atenolol	0.4	0.5	4.8	0.2	-0.2	-0.4	-0.2	0.4	0.1	-0.4	1.2	-0.6	-0.2	0.4	-0.1	-1.4	-2.2	0.1	0.4	0.1	0.4
Number of incorrect matches in round	0.4	0.7	2.5	0.7	0.8	0.6	0.6	1.0	0.9	0.6	0.7	0.6	0.9	0.9	0.8	-0.1	-0.5	1.6	0.7	0.9	1.1
Qualifications: None of the above	0.4	0.9	3.7	-0.3	-0.9	-0.8	-1.0	-0.3	-0.6	-0.8	-1.1	-0.5	-0.4	-0.9	-0.4	-1.9	-0.6	-1.8	-0.4	-0.5	-1.5
Worrier / anxious feelings	0.4	0.7	7.3	0.3	-0.3	0.3	-1.1	0.3	0.3	0.3	-2.7	-0.2	0.3	0.3	0.5	-0.1	-1.1	0.4	0.3	0.5	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.9	-0.5	-1.0	-1.1	-0.6	-0.4	-0.3	-1.0	-0.4	-0.6	-1.0	-0.3	-1.0	-0.2	-1.7	-0.0	-0.9	-0.9	-0.2
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	3.9	-1.3	-1.0	-0.4	-2.0	-1.7	-1.2	-0.5	-1.3	-0.8	-0.7	-1.2	-0.7	-0.2	1.3	-0.5	-0.8	-0.8	-1.5
Exposure to tobacco smoke at home	0.4	0.4	3.7	0.1	0.3	-0.2	0.6	-0.0	-0.1	-0.2	1.2	-0.6	-0.4	0.0	-0.1	-1.9	-0.6	0.0	-0.1	-0.2	-0.9
Birth weight of first child	0.4	0.7	2.2	-0.7	-0.6	-0.8	-0.4	-0.7	-0.9	-0.8	-1.5	-0.9	-0.8	-1.0	-0.7	-1.0	-0.6	-0.5	-0.6	-0.8	-0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.9	-0.8	-0.0	-0.1	-0.3	-1.0	-0.9	-0.1	-1.3	-0.8	-0.5	-0.8	-0.2	-0.3	1.3	-1.2	-0.4	-0.4	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	3.5	-0.2	0.2	0.2	0.2	-0.4	-0.4	0.2	0.4	-0.1	-0.1	-0.9	0.1	-0.4	0.6	-1.9	-0.4	-0.1	-1.8
Neck or shoulder pain in last month	0.4	0.5	3.0	-0.0	-0.5	-0.3	-0.4	-0.3	-0.3	-0.3	-1.1	-0.5	-0.5	-0.5	-0.3	-1.0	0.1	-1.7	0.0	-0.4	-1.4
Angina (self-reported)	0.4	0.5	3.1	0.7	0.1	0.1	0.6	0.9	1.0	0.2	1.2	0.7	0.2	0.9	0.2	0.4	-0.1	0.4	0.4	0.4	1.8
Pulse rate, automated reading	0.4	1.3	9.5	1.1	1.0	0.9	1.5	1.0	0.9	1.0	3.1	0.5	0.6	0.6	1.0	0.3	0.6	-0.7	1.1	0.8	-0.7
Supplements: Vitamin C	0.4	0.5	1.9	0.9	1.0	0.7	1.4	0.8	0.6	0.7	0.5	0.2	0.5	0.4	0.8	-0.3	0.2	-0.7	0.8	0.6	-0.7
Ever taken oral contraceptive pill	0.4	0.5	0.8	-0.7	-0.4	-0.8	-0.4	-0.6	-0.8	-0.8	0.3	-0.7	-0.7	-0.8	-0.7	-0.8	-0.6	-0.6	-0.9	-0.8	-0.7
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.2	-0.5	-0.6	-0.8	-0.2	-0.3	-0.3	-0.9	1.5	-0.9	-0.6	0.0	-0.6	-0.9	-1.3	0.2	-0.2	-0.4	1.0
Pack years of smoking	0.4	0.6	3.9	0.3	0.8	0.5	1.4	0.3	0.3	0.5	2.0	0.3	0.1	-0.5	0.4	-0.4	1.0	-1.4	0.1	0.2	-0.4
Depression (Nagel 2018)	0.3	0.5	2.2	-0.6	-0.7	-0.5	-0.8	-0.7	-0.6	-0.5	-0.4	-0.6	-0.6	-0.6	-0.5	-1.2	-0.2	-0.7	-0.5	-0.5	-1.5
Worry (Nagel 2018)	0.3	0.7	2.0	0.7	0.5	1.0	-0.3	0.7	0.7	1.0	-1.4	0.7	1.0	0.6	1.1	0.6	0.7	0.2	0.8	1.0	-0.8
Prostate Cancer	0.3	0.4	2.8	0.3	0.2	0.3	0.4	0.2	-0.1	0.4	-0.1	0.5	0.2	0.1	0.3	0.4	1.7	-1.2	0.1	0.1	-1.2
Neuroticism (2016)	0.3	0.5	2.2	-0.2	-0.5	-0.1	-0.9	-0.4	-0.3	-0.1	-1.3	-0.6	-0.4	-0.1	-0.1	-1.2	-0.5	-0.9	-0.1	-0.2	-1.5
Rheumatoid Arthritis	0.3	0.4	0.8	0.5	0.9	0.8	0.9	0.6	0.5	0.8	0.3	0.8	0.7	0.5	0.7	0.6	-0.0	0.9	0.3	0.7	0.6
Ulcerative Colitis	0.3	0.4	3.4	-0.0	0.2	0.2	0.5	-0.1	-0.1	0.2	1.8	0.4	-0.0	-0.1	-0.0	-0.2	1.7	0.1	-0.1	-0.2	-0.7
Respiratory disease	0.3	0.7	2.6	-0.4	-0.4	-0.7	-0.2	-0.3	-0.5	-0.7	0.1	-0.7	-0.8	-0.6	-0.6	-0.7	-1.6	-1.6	-0.5	-0.6	-1.3
Neuroticism	0.3	0.7	3.9	-0.5	-0.7	-0.1	-1.4	-0.4	-0.6	-0.2	-1.7	-0.5	-0.2	-0.5	-0.1	-0.9	0.0	-0.8	-0.3	-0.2	-2.0
Frequency of depressed mood in last 2 weeks	0.3	0.5	4.4	-0.1	0.0	0.2	-0.1	-0.3	-0.4	0.2	-0.4	-0.0	-0.2	-0.6	0.1	-0.3	0.7	-1.6	-0.1	-0.1	-2.1
Vitamin and mineral supplements	0.3	0.4	2.0	-0.4	-0.5	-0.1	-0.9	-0.3	-0.0	-0.1	-0.7	0.3	0.2	0.2	-0.2	0.9	0.9	1.4	-0.2	-0.1	1.3
Hand grip strength (right)	0.3	1.0	4.5	0.7	0.1	0.2	-0.6	0.7	0.9	0.2	-0.6	0.2	0.8	1.6	0.6	-0.4	-0.5	2.1	1.8	0.8	1.3
Average weekly fortified wine intake	0.3	0.4	1.0	0.8	0.7	0.7	1.0	0.8	0.7	0.7	-0.0	0.6	0.5	0.8	0.6	0.5	0.4	0.3	0.4	0.6	0.6
Taking other prescription medications	0.3	0.4	3.0	-0.3	-0.3	-0.0	-0.4	-0.5	-0.2	-0.0	-0.6	-0.1	-0.3	-0.7	-0.2	0.2	0.8	-1.7	-0.2	-0.3	-1.3
Nervous feelings	0.3	0.5	2.2	0.6	0.2	0.8	-0.6	0.7	0.5	0.8	-0.8	0.6	0.7	0.6	0.9	0.2	0.6	0.0	0.4	0.7	-1.5
Mouth/teeth dental problems	0.3	0.5	3.6	-0.5	-0.6	-0.5	-0.5	-0.2	-0.4	-0.5	-1.9	0.1	-0.3	-0.3	-0.6	0.9	0.3	0.1	-0.5	-0.4	1.4
Heart attack	0.3	0.4	2.9	-0.3	-0.3	-0.6	0.1	-0.1	-0.1	-0.6	1.7	-0.6	-0.4	0.1	-0.4	-0.6	-1.2	0.3	0.0	-0.2	1.1
Pain all over the body in last month	0.3	0.3	1.3	0.7	0.5	0.3	0.5	0.5	0.5	0.3	0.3	-0.1	0.6	0.6	0.7	-1.1	-0.7	-0.1	0.9	0.7	-0.1
Neuroticism score	0.3	0.5	3.1	-0.5	-0.7	-0.1	-1.6	-0.4	-0.6	-0.2	-1.3	-0.5	-0.2	-0.4	-0.1	-0.5	0.2	-0.5	-0.1	-0.2	-1.8
Arm fat percentage (right)	0.3	1.1	10.7	0.7	1.0	0.7	1.8	0.7	0.6	0.8	3.3	0.8	0.5	0.0	0.6	0.1	0.8	-0.6	0.4	0.4	0.1
Falls in the last year	0.3	0.4	1.5	0.6	0.6	0.5	1.0	0.6	0.5	0.5	0.9	1.0	0.6	0.2	0.5	1.2	0.8	0.0	0.1	0.4	0.3
Noisy workplace	0.3	0.4	1.0	1.0	0.5	0.4	0.8	1.0	0.6	0.4	0.7	0.5	0.5	0.9	0.6	-0.1	0.3	0.0	0.7	0.6	-0.1
Lung cancer (father)	0.3	0.4	1.3	-0.6	-0.4	0.0	-0.8	-0.5	-0.6	0.0	0.9	-0.4	-0.2	-0.6	-0.2	-0.6	1.1	-0.7	-0.1	-0.3	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	4.2	-1.2	-1.1	-0.6	-2.0	-1.6	-1.1	-0.7	-1.4	-0.7	-0.7	-1.0	-0.8	0.1	0.8	-0.1	-1.1	-0.8	-1.0
Breastfed as a baby	0.3	0.4	1.2	-0.9	-0.4	-0.4	-0.3	-0.7	-0.7	-0.4	0.9	-0.2	-0.6	-0.3	-0.7	1.1	1.1	0.3	-0.5	-0.7	0.0
Medication: Paracetamol	0.3	0.5	2.6	0.8	-0.1	0.5	-0.8	0.8	0.5	0.5	-1.6	0.3	0.5	0.5	0.7	-0.6	0.0	-0.4	0.9	0.6	-1.2
Worry too long after embarrassment	0.3	0.4	3.1	0.1	-0.6	0.1	-1.8	0.1	0.1	0.1	-1.6	-0.0	0.3	0.4	0.3	-0.1	-0.1	0.6	0.2	0.3	-1.0
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.5	-0.3	-0.6	-0.6	-0.8	-0.4	-0.5	-0.6	-0.0	-0.4	-0.4	-0.3	-0.4	-1.1	-1.0	0.0	-0.8	-0.5	-1.2
Migraine (self-reported)	0.3	0.3	2.4	-0.4	-0.5	-0.1	-0.5	-0.3	-0.1	-0.1	-1.6	0.0	-0.3	-0.5	-0.4	1.2	-0.7	0.1	-0.4	-0.3	0.3
Medication: Seretide 50 evohaler	0.3	0.3	0.8	-0.3	-0.7	-0.8	-0.1	-0.4	-0.4	-0.7	-0.9	-0.3	-0.8	-0.3	-0.8	-0.2	-0.4	-0.4	-0.9	-0.8	-0.1
Comparative height size at age 10	0.3	1.8	7.0	0.8	0.9	1.3	-0.1	0.6	1.1	1.3	-0.2	1.4	1.5	1.1	1.2	2.6	1.4	2.2	1.0	1.3	1.7
Number of full sisters	0.3	0.4	0.9	-0.5	-0.6	-0.6	-0.1	-0.4	-0.5	-0.6	-0.0	-0.7	-0.9	-0.7	-0.7	-0.6	-0.9	-0.7	-0.8	-0.7	-0.4
Chest pain or discomfort	0.3	0.4	1.5	0.8	0.5	0.2	1.2	0.5	0.7	0.2	1.1	-0.1	0.1	0.3	0.4	-0.6	-1.1	-0.8	0.6	0.4	-0.4
Had major operations	0.3	0.4	1.1	-0.6	-0.2	-0.2	-0.8	-0.6	-0.6	-0.3	-0.4	-0.8	-0.3	-0.7	-0.1	-0.6	-1.0	-1.1	-0.1	-0.2	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.8	0.8	0.2	0.4	0.3	0.8	0.9	0.4	0.8	0.5	0.4	0.9	0.4	0.7	0.0	0.5	0.5	0.5	0.4
Commuting to job workplace: Walk	0.3	0.3	0.7	0.6	0.7	0.6	0.7	0.7	0.6	0.6	0.4	0.8	0.5	0.6	0.5	0.4	0.6	0.5	0.4	0.5	0.4
Back pain experienced in last month	0.3	0.5	1.9	0.9	0.4	0.7	0.2	0.7	0.8	0.7	0.1	0.6	0.6	0.9	0.6	0.5	0.9	-0.1	1.4	0.7	-0.2
Breast cancer (self-reported)	0.3	0.3	1.0	-0.3	-1.0	-0.7	-0.6	-0.4	-0.2	-0.7	-0.9	-0.0	-0.6	-0.4	-0.8	0.5	-0.2	-0.2	-0.6	-0.7	0.2
Wears glasses or contact lenses	0.3	0.4	0.9	-0.4	-0.8	-0.9	-0.5	-0.5	-0.4	-0.9	0.2	-0.4	-0.7	-0.4	-0.8	-0.1	-0.9	-0.4	-0.7	-0.8	-0.1
Hearing aid user	0.3	0.3	1.7	-0.6	-0.6	-0.6	-0.7	-0.4	-0.4	-0.6	-0.1	-0.7	-0.5	-0.3	-0.6	-0.4	-1.3	0.4	-0.4	-0.5	0.5
Illnesses of father: High blood pressure	0.3	0.3	1.2	0.0	0.7	0.9	0.5	0.1	0.1	0.9	-0.5	0.5	0.4	-0.4	0.5	1.1	1.0	-0.6	0.3	0.4	-0.1
Diastolic blood pressure, automated reading	0.3	1.1	2.5	1.1	0.8	0.8	0.6	1.0	1.0	0.8	1.5	0.7	1.1	1.4	1.0	-0.6	-0.0	1.5	1.6	1.1	0.6
Pain experienced in last month	0.3	0.5	4.1	0.4	0.5	0.3	0.6	0.5	0.5	0.3	-0.0	0.4	0.7	0.5	0.4	-0.2	-0.7	2.0	0.2	0.5	1.4
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.8	0.4	0.4	0.3	0.5	0.6	0.6	0.3	0.9	-0.1	0.1	1.0	0.2	0.9	-0.5	1.7	0.2	0.4	1.3
Triglycerides	0.2	0.3	0.8	0.5	0.6	0.4	0.8	0.8	0.4	0.4	0.9	0.2	0.4	0.5	0.6	-0.1	-0.1	-0.5	0.5	0.6	-0.1
Blood White Count	0.2	1.8	6.5	-1.2	-1.2	-1.6	-0.1	-1.0	-1.1	-1.5	1.2	-0.3	-1.4	-1.9	-1.8	0.2	-0.3	-0.7	-2.5	-1.8	0.8
Tanning	0.2	2.0	5.2	-1.4	-1.4	-1.3	-1.8	-1.6	-1.6	-1.4	-0.9	-1.1	-1.2	-1.5	-1.2	-1.2	-0.3	-1.8	-1.4	-1.3	-2.3
Average weekly spirits intake	0.2	0.3	2.0	-0.3	-0.3	-0.4	-0.3	-0.2	-0.5	-0.4	-0.6	-0.5	-0.4	-0.1	-0.4	-1.4	-0.8	0.1	-0.4	-0.4	-0.6
Hearing difficulty/problems: Yes	0.2	0.2	1.0	-0.3	-0.2	-0.5	-0.2	-0.0	-0.2	-0.5	0.9	-0.6	-0.3	0.1	-0.4	-0.7	-1.0	0.4	-0.0	-0.3	0.5
Medication: Co-codamol	0.2	0.2	0.8	-0.5	-0.4	-0.5	-0.3	-0.2	-0.2	-0.5	-0.2	-0.1	-0.5	-0.3	-0.6	0.8	-0.9	-0.2	-0.5	-0.5	0.4
Trunk fat percentage	0.2	0.8	7.2	0.6	0.9	0.7	1.5	0.5	0.4	0.7	2.7	0.6	0.5	-0.2	0.6	0.2	0.9	-0.9	0.4	0.4	-0.1
Townsend deprivation index at recruitment	0.2	0.3	2.2	0.4	0.3	0.1	0.7	0.5	0.4	0.2	1.5	0.6	0.3	0.4	0.2	0.3	0.1	0.7	0.2	0.2	0.5
Relative age voice broke	0.2	0.3	1.1	-0.3	-0.2	0.1	-0.5	-0.2	-0.3	0.1	-1.0	0.1	-0.1	-0.2	-0.1	0.8	1.0	-0.8	-0.4	-0.1	-0.7
Stomach or abdominal pain in last month	0.2	0.2	1.9	-0.0	0.1	0.1	-0.0	-0.0	0.0	0.1	-1.1	-0.1	0.1	-0.7	0.2	-0.2	-0.0	-1.4	0.1	0.1	-0.7
Sitting height	0.2	1.8	5.1	1.0	1.4	1.7	0.5	0.9	1.4	1.7	0.7	1.4	1.5	1.3	1.6	2.3	0.4	1.2	0.9	1.6	1.0
Trunk fat mass	0.2	0.9	5.6	0.8	1.1	0.9	1.4	0.7	0.7	0.9	2.4	0.7	0.8	0.2	0.9	0.1	0.8	-0.6	0.9	0.8	0.2
Waist circumference	0.2	0.7	4.8	0.7	0.8	0.7	1.4	0.8	0.7	0.7	2.2	0.7	0.5	0.2	0.6	0.1	0.3	-0.4	0.5	0.5	0.6
Past tobacco smoking	0.2	0.3	1.8	0.1	0.4	0.1	1.0	0.3	0.2	0.1	1.4	0.4	-0.1	0.5	-0.1	0.7	-0.0	0.9	-0.5	-0.1	0.7
Alcohol usually taken with meals	0.2	0.4	2.4	-0.7	-0.6	-0.2	-0.8	-0.6	-0.4	-0.2	-1.5	-0.6	-0.6	-0.6	-0.5	0.4	-0.9	-0.4	-0.6	-0.4	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.8	0.6	0.0	0.4	-0.0	0.4	0.7	0.4	-0.8	0.6	0.4	0.4	0.4	1.3	-0.2	0.3	0.1	0.4	-0.2
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.9	-0.1	-0.2	-0.1	-0.4	-0.2	-0.1	-0.0	-1.4	-0.2	-0.3	-0.3	-0.1	0.3	-0.4	-1.2	-0.1	-0.2	-0.7
Fluid intelligence score	0.2	0.4	2.4	-0.7	-0.3	-0.3	-0.3	-0.6	-0.5	-0.3	-1.6	-0.8	-0.6	-0.7	-0.5	-0.2	-0.4	0.4	-0.3	-0.5	0.3
Weight	0.2	1.1	2.7	1.0	1.3	1.2	1.4	1.0	1.0	1.2	1.6	0.9	1.1	0.6	1.2	0.0	0.5	0.1	1.4	1.1	0.8
Pulse wave Arterial Stiffness index	0.2	0.2	0.9	0.6	0.4	0.3	0.3	0.4	0.5	0.3	0.9	0.1	0.3	0.5	0.4	-0.7	-0.4	0.3	0.7	0.4	0.3
Arm fat mass (right)	0.2	0.9	5.3	0.9	1.0	0.8	1.6	0.9	0.8	0.9	2.3	0.8	0.7	0.3	0.7	0.1	0.6	-0.4	0.8	0.6	0.5
Tense / ‘highly strung’	0.2	0.3	1.1	-0.2	0.3	0.6	-0.4	0.0	-0.3	0.6	-0.7	0.3	0.5	-0.5	0.5	0.5	1.1	-0.6	0.3	0.4	-1.0
Headache pain in last month	0.2	0.4	0.7	-0.6	-0.5	-0.8	-0.1	-0.7	-0.5	-0.7	-0.1	-0.6	-0.8	-0.5	-0.8	-0.4	-0.8	-0.4	-0.8	-0.8	0.2
Gout (self-reported)	0.2	0.3	1.3	-0.5	-0.5	-0.5	-0.3	-0.4	-0.5	-0.5	-0.4	0.1	-0.4	-0.7	-0.7	0.5	1.1	-0.7	-0.8	-0.6	0.2
Body fat percentage	0.2	0.7	7.9	0.4	0.6	0.4	1.3	0.4	0.3	0.5	2.8	0.5	0.2	-0.3	0.3	-0.1	0.8	-0.8	0.2	0.2	0.0
Number of full brothers	0.2	0.3	2.5	-0.1	-0.0	-0.2	0.5	-0.2	0.1	-0.2	1.6	0.1	-0.3	0.0	-0.3	0.5	-0.0	-0.0	-0.6	-0.3	1.0
Number of children fathered	0.2	0.3	2.3	-0.4	0.1	0.2	-0.1	-0.3	-0.0	0.1	-0.3	0.2	0.2	-0.3	0.0	1.2	0.6	0.1	-0.2	0.1	1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.9	0.6	0.0	0.3	-0.2	0.6	0.7	0.3	-0.7	0.5	0.3	0.5	0.4	1.0	-0.5	0.0	0.4	0.5	0.5
Age at first live birth	0.2	0.3	1.4	-0.4	-0.5	-0.5	-0.4	-0.5	-0.1	-0.5	-0.7	-0.3	-0.5	-0.1	-0.7	0.4	-0.2	1.2	-0.7	-0.6	0.8
Pulse wave peak to peak time	0.2	0.2	1.2	-0.6	-0.3	-0.2	-0.4	-0.4	-0.4	-0.2	-1.1	-0.0	-0.3	-0.4	-0.4	0.7	0.3	-0.2	-0.6	-0.3	-0.2
Whole body fat mass	0.2	0.7	5.8	0.7	0.9	0.6	1.4	0.6	0.5	0.7	2.4	0.5	0.5	0.1	0.6	-0.3	0.4	-0.6	0.7	0.5	0.3
Alcohol intake frequency.	0.2	0.5	3.0	0.1	-0.4	-0.2	-0.1	-0.1	-0.2	-0.2	-0.1	-0.3	-0.4	-0.5	-0.2	-1.5	0.2	-1.5	0.1	-0.3	-1.7
Smoking status: Previous	0.2	0.3	2.7	-0.1	-0.5	-0.3	-0.9	-0.1	-0.1	-0.3	-1.6	-0.4	0.0	-0.2	-0.1	-0.8	-0.5	-0.5	0.4	0.0	0.1
Leg fat-free mass (right)	0.2	1.0	2.3	0.9	1.4	1.1	1.2	1.0	0.9	1.0	0.7	0.7	1.1	0.9	1.2	-0.2	0.2	0.6	1.5	1.1	1.0
Arm fat percentage (left)	0.2	0.8	8.5	0.6	0.8	0.5	1.5	0.6	0.4	0.6	2.9	0.6	0.3	-0.1	0.4	-0.1	0.6	-0.7	0.3	0.3	0.0
Qualifications: nursing, teaching	0.2	0.3	0.8	-0.6	-0.5	-0.5	-0.3	-0.7	-0.6	-0.5	-0.2	-0.6	-0.9	-0.5	-0.7	-0.3	0.4	-0.6	-0.7	-0.8	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.4	-0.7	-0.8	-0.4	-1.1	-0.9	-0.7	-0.4	-0.5	-0.4	-0.4	-0.8	-0.5	-0.3	1.2	-0.3	-0.6	-0.6	-1.0
Leg predicted mass (right)	0.2	0.9	2.2	0.8	1.3	1.0	1.1	1.0	0.8	1.0	0.7	0.6	1.1	0.8	1.1	-0.3	0.2	0.6	1.5	1.1	0.9
Arm fat mass (left)	0.2	0.7	4.1	0.8	0.9	0.7	1.6	0.8	0.7	0.7	2.0	0.7	0.6	0.2	0.6	-0.2	0.3	-0.4	0.7	0.6	0.5
Basal metabolic rate	0.2	0.9	2.6	0.9	1.2	1.1	0.8	1.0	1.0	1.0	0.4	0.6	1.2	0.9	1.2	-0.2	-0.1	0.6	1.6	1.2	1.0
Commuting to job workplace: Cycle	0.2	0.2	1.9	-0.4	0.2	0.1	0.1	-0.3	-0.5	0.1	-0.8	0.1	0.0	-0.4	-0.0	0.4	1.4	0.3	-0.1	-0.1	-0.0
Basal cell carcinoma (self-reported)	0.2	0.2	0.8	0.4	-0.4	-0.2	0.1	0.4	0.2	-0.1	0.9	0.1	-0.4	0.5	-0.2	-0.6	-0.5	-0.8	-0.1	-0.2	-0.6
Bipolar Disorder (2018)	0.1	0.1	0.5	-0.2	-0.4	-0.2	-0.2	-0.1	-0.3	-0.2	0.4	-0.2	-0.5	-0.1	-0.3	-0.2	-0.5	-0.7	-0.6	-0.3	-0.6
Bipolar Disorder or Schizophrenia	0.1	0.1	0.9	-0.0	-0.3	-0.0	-0.4	0.1	0.1	-0.0	1.0	0.2	-0.1	-0.1	-0.1	0.5	-0.6	0.3	-0.6	-0.1	-0.1
Schizophrenia (2018)	0.1	0.2	1.7	0.2	0.1	0.1	-0.1	0.3	0.3	0.1	1.3	0.5	0.2	-0.0	0.1	0.8	-0.4	0.9	-0.3	0.2	0.3
Ulcerative Colitis (UC)	0.1	0.3	1.9	0.3	0.5	0.5	0.5	0.2	0.1	0.5	1.4	0.3	0.3	0.1	0.4	-0.6	0.7	-0.1	0.5	0.3	-0.5
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.3	0.4	0.6	0.5	0.8	0.5	0.6	0.6	-0.0	-0.0	0.3	0.5	0.4	0.4	-0.4	1.2	0.6	0.5	1.1
Schizophrenia (2014)	0.1	0.3	1.1	-0.5	-0.6	-0.3	-0.9	-0.3	-0.3	-0.3	0.9	-0.1	-0.5	-0.4	-0.5	0.6	-0.8	0.4	-1.1	-0.4	-0.0
Blood Eosinophil Count	0.1	0.8	5.3	0.2	-0.3	-0.5	1.2	0.0	0.3	-0.4	2.3	0.4	-1.0	0.4	-1.0	0.8	1.1	0.7	-0.9	-1.0	0.3
Height	0.1	1.4	8.2	-0.9	-0.2	0.1	-1.9	-1.0	-0.6	-0.1	-2.9	-1.6	0.1	-0.4	0.3	-1.8	-2.1	0.3	0.8	0.4	-0.4
Hypothyroidism (self reported)	0.1	0.2	1.7	0.2	-0.3	-0.2	-0.9	0.1	0.3	-0.2	-0.8	-0.2	0.1	0.3	0.1	-0.5	-1.3	0.2	0.3	0.2	-0.4
Hair Pigment	0.1	2.4	11.4	-1.4	-0.8	-1.1	-1.0	-1.4	-1.9	-1.1	0.2	-1.8	-1.4	-1.7	-1.0	-2.0	0.2	-2.1	-1.2	-1.2	-3.4
Supplements: Zinc	0.1	0.1	0.6	0.3	-0.1	-0.0	-0.3	0.1	0.2	-0.0	-0.8	0.0	-0.0	0.2	0.1	-0.1	-0.6	-0.3	0.2	0.1	-0.8
Impedance of leg (right)	0.1	0.5	2.7	-0.6	-0.9	-0.3	-1.6	-0.9	-0.3	-0.3	-1.0	-0.5	-0.4	-0.5	-0.3	0.8	-0.5	-0.5	-0.8	-0.3	-1.0
Leg fat-free mass (left)	0.1	0.7	1.8	0.7	1.1	0.9	1.0	0.8	0.7	0.9	0.9	0.5	0.9	0.7	1.0	-0.4	-0.0	0.6	1.3	1.0	0.9
Fed-up feelings	0.1	0.2	1.1	0.1	-0.4	-0.2	-0.4	0.1	-0.0	-0.2	-0.3	-0.1	-0.2	0.1	-0.1	-1.0	-0.7	-0.4	-0.1	-0.1	-0.6
Age when periods started (menarche)	0.1	0.3	1.7	-0.3	0.2	0.4	-0.0	-0.6	-0.3	0.4	-0.0	-0.2	0.0	-0.5	0.2	-0.0	1.3	-0.9	-0.3	0.0	-1.2
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	1.3	0.2	0.4	0.3	0.4	0.1	-0.0	0.3	1.2	-0.0	0.3	0.0	0.4	-0.3	-0.7	0.1	0.4	0.4	0.2
Serious illness, injury or assault to yourself	0.1	0.1	0.4	-0.2	-0.2	-0.3	0.1	-0.4	-0.3	-0.3	0.1	-0.4	-0.3	-0.4	-0.2	-0.7	-0.5	-0.3	-0.2	-0.3	-0.5
Multivitamins +/- minerals	0.1	0.2	1.0	0.2	0.2	-0.2	0.5	0.1	-0.1	-0.2	1.0	-0.2	-0.3	-0.1	-0.1	-0.4	-0.8	-0.9	-0.0	-0.1	-0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	1.5	-0.4	0.2	0.0	0.4	-0.3	-0.3	0.0	1.2	-0.3	-0.2	-0.4	-0.1	0.3	0.5	-0.4	-0.1	-0.2	0.0
Medication: Levothyroxine sodium	0.1	0.2	1.4	0.1	-0.0	0.3	-0.5	0.1	0.3	0.3	-0.9	0.5	0.4	0.2	0.2	1.2	0.5	0.3	0.1	0.2	0.2
Body mass index (BMI)	0.1	0.6	5.1	0.6	0.6	0.3	1.5	0.6	0.4	0.3	2.3	0.4	0.2	0.0	0.3	-0.7	0.3	-0.6	0.6	0.2	0.4
Impedance of leg (left)	0.1	0.5	1.8	-0.5	-0.7	-0.2	-1.4	-0.8	-0.4	-0.2	-1.1	-0.3	-0.3	-0.5	-0.2	1.1	0.1	-0.7	-0.7	-0.2	-0.9
Leg predicted mass (left)	0.1	0.8	1.9	0.8	1.2	0.9	1.0	0.9	0.8	0.9	0.9	0.5	0.9	0.7	1.0	-0.4	-0.1	0.5	1.4	1.0	0.8
Impedance of arm (right)	0.1	0.2	2.2	-0.1	0.2	0.4	-0.3	-0.3	0.0	0.4	0.4	0.2	0.0	-0.2	0.2	1.5	0.4	0.0	-0.7	0.1	-0.9
Trunk fat-free mass	0.1	0.8	2.5	0.8	1.0	1.0	0.2	0.8	0.9	1.0	-0.5	0.5	1.2	0.9	1.2	-0.1	-0.4	0.8	1.6	1.2	0.9
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.0	-0.7	0.1	0.2	-0.3	-0.8	-0.6	0.1	-0.4	-0.4	-0.2	-0.8	-0.1	0.6	1.0	-0.4	-0.3	-0.2	-0.4
Medication: Lansoprazole	0.1	0.2	0.8	-0.2	-0.4	-0.4	-0.3	-0.3	-0.1	-0.4	0.1	-0.1	-0.5	-0.3	-0.4	0.7	-0.5	-0.2	-0.9	-0.4	0.1
Impedance of arm (left)	0.1	0.3	2.6	-0.1	0.0	0.3	-0.5	-0.3	-0.0	0.3	-0.1	0.2	-0.0	-0.2	0.2	1.6	0.5	-0.1	-0.6	0.1	-0.9
Trunk predicted mass	0.1	0.8	2.6	0.8	0.9	1.0	0.2	0.8	0.9	0.9	-0.6	0.5	1.2	0.9	1.2	-0.2	-0.5	0.7	1.6	1.2	0.9
Standing height	0.1	1.4	2.7	0.7	1.2	1.6	-0.4	0.5	1.0	1.5	-1.6	0.7	1.6	0.9	1.6	1.4	0.3	1.0	1.4	1.6	0.5
Peak expiratory flow (PEF)	0.1	0.3	1.1	0.4	0.3	0.7	-0.3	0.1	0.3	0.7	-1.0	-0.2	0.3	0.2	0.6	-0.3	0.4	-0.4	0.9	0.5	-1.1
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.7	-0.2	-0.3	-0.3	-0.1	-0.2	-0.4	-0.3	0.3	-0.4	-0.2	-0.4	-0.2	-0.7	0.3	-0.9	-0.3	-0.3	-0.7
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.3	-0.4	-0.5	-0.4	-1.0	-0.3	-0.2	-0.4	-1.1	-0.3	-0.1	-0.2	-0.2	-0.1	-0.7	0.1	-0.2	-0.2	-0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.1	-0.1	-0.3	-0.2	-0.1	-0.2	-0.1	-0.1	0.0	0.1	-0.3	-0.4	-0.3	0.7	-0.1	-1.1	-0.6	-0.3	-0.7
High blood pressure (siblings)	0.1	0.2	1.4	0.0	-0.1	0.1	0.1	-0.1	-0.2	0.1	0.4	-0.1	-0.1	-0.4	0.0	-0.4	-0.1	-1.2	-0.1	-0.1	-1.1
Leg fat percentage (right)	0.1	0.4	5.5	0.0	-0.1	-0.2	0.5	0.1	0.0	-0.2	2.3	-0.1	-0.2	-0.3	-0.2	-1.0	0.1	-0.8	0.2	-0.2	0.0
Arm fat-free mass (right)	0.1	0.4	1.7	0.5	0.5	0.4	0.2	0.5	0.5	0.3	-0.6	0.0	0.7	0.5	0.7	-1.0	-0.6	0.2	1.3	0.7	0.7
Qualifications: College or University degree	0.1	0.3	2.5	-0.4	0.2	0.1	-0.0	-0.6	-0.2	0.1	-0.2	0.1	-0.0	-0.1	-0.1	1.6	-0.0	0.7	-0.4	-0.1	0.8
Medication: Ibuprofen	0.1	0.2	0.5	0.2	0.5	0.4	0.4	0.4	0.2	0.4	0.5	0.2	0.3	0.1	0.4	-0.0	0.7	-0.6	0.7	0.4	-0.4
Heart disease (mother)	0.1	0.2	1.1	-0.1	-0.1	-0.1	-0.1	-0.3	-0.2	-0.1	-1.1	-0.3	-0.0	-0.0	-0.1	-0.7	-0.4	0.9	0.3	-0.1	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	1.1	-0.1	0.1	0.2	0.0	-0.2	-0.1	0.2	-1.0	-0.3	-0.0	-0.3	0.1	-0.1	-0.1	-0.9	0.3	0.1	-0.2
Leg fat mass (right)	0.1	0.3	3.2	0.1	0.1	-0.1	0.7	0.1	0.1	-0.1	1.8	-0.1	-0.1	-0.3	-0.1	-1.2	-0.3	-0.7	0.3	-0.1	0.2
Arm predicted mass (right)	0.1	0.3	1.4	0.5	0.5	0.4	0.2	0.5	0.4	0.3	-0.8	0.0	0.7	0.5	0.6	-0.8	-0.6	0.1	1.2	0.7	0.7
Age at last live birth	0.1	0.1	0.4	-0.1	-0.4	-0.3	-0.5	-0.1	0.1	-0.3	-0.4	-0.3	-0.4	0.2	-0.4	0.2	-0.6	0.7	-0.2	-0.2	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	1.3	-0.0	0.1	-0.2	0.2	0.1	0.2	-0.2	0.6	0.2	0.0	0.3	-0.1	1.1	-0.0	0.5	-0.1	-0.1	0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.8	0.1	0.5	0.6	-0.5	0.0	0.2	0.5	-0.9	-0.1	0.6	0.2	0.7	0.3	-0.7	0.2	0.5	0.7	-0.2
Whole body fat-free mass	0.1	0.6	2.1	0.7	1.0	0.9	0.5	0.8	0.7	0.8	-0.0	0.4	1.0	0.8	1.0	-0.4	-0.4	0.6	1.5	1.0	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.7	0.2	-0.3	-0.1	-0.1	0.2	-0.0	-0.1	-0.8	0.1	0.2	-0.1	0.1	-0.5	0.7	-0.4	0.2	0.0	-0.3
Medication for cholesterol	0.1	0.1	0.9	0.1	0.3	0.2	0.3	-0.1	0.0	0.3	1.0	0.2	-0.0	0.2	0.1	0.7	0.8	-0.0	-0.2	-0.0	-0.4
Whole body water mass	0.1	0.6	2.0	0.7	0.9	0.8	0.5	0.7	0.7	0.8	-0.1	0.4	1.0	0.7	1.0	-0.4	-0.4	0.5	1.4	1.0	0.9
Ever smoked	0.1	0.2	1.2	0.3	0.1	0.4	-0.5	0.1	0.2	0.4	-0.2	0.3	0.5	-0.2	0.5	-0.0	0.7	-0.8	0.6	0.4	-1.1
Leg fat percentage (left)	0.1	0.4	5.4	0.1	0.0	-0.1	0.7	0.1	0.0	-0.1	2.3	0.1	-0.1	-0.3	-0.1	-0.8	0.5	-0.9	0.2	-0.2	0.1
Arm fat-free mass (left)	0.1	0.4	1.6	0.6	0.6	0.6	0.4	0.6	0.6	0.5	-0.4	0.3	0.8	0.5	0.8	-0.6	-0.2	0.1	1.2	0.8	0.8
Average weekly beer plus cider intake	0.1	0.1	1.3	-0.4	-0.1	-0.3	0.0	-0.3	-0.3	-0.3	1.2	-0.2	-0.3	-0.5	-0.3	-0.0	0.1	-0.3	-0.3	-0.3	0.2
Myopia	0.1	0.1	1.0	-0.0	0.3	0.0	1.0	0.1	-0.0	0.1	-0.5	0.2	-0.2	-0.4	-0.2	-0.2	0.3	-0.1	-0.5	-0.3	0.6
Impedance of whole body	0.1	0.3	2.7	-0.0	0.0	0.5	-0.5	-0.3	0.0	0.4	-0.1	0.2	0.1	-0.2	0.3	1.6	0.8	-0.5	-0.5	0.2	-1.1
Leg fat mass (left)	0.1	0.3	2.7	0.1	0.2	-0.1	0.7	0.1	-0.0	-0.1	1.6	-0.1	-0.1	-0.4	-0.1	-1.2	0.0	-0.9	0.3	-0.2	0.1
Arm predicted mass (left)	0.1	0.7	2.2	0.8	1.0	0.9	0.7	0.9	0.8	0.8	-0.1	0.5	1.0	0.7	1.0	-0.6	0.0	0.3	1.5	1.0	0.9
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Illnesses of siblings	0.0	0.0	0.3	-0.2	0.1	-0.1	-0.2	-0.3	-0.2	-0.1	-0.5	-0.4	-0.0	-0.0	-0.0	-0.2	-0.2	0.2	-0.0	0.0	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.1	0.3	0.2	0.0	0.1	-0.1	0.3	0.2	0.1	0.3	0.1	0.1	0.2	0.2	-0.1	0.5	-0.3	0.5	0.2	-0.1
Exposure to tobacco smoke outside home	0.0	0.1	0.4	0.1	-0.2	-0.1	0.2	-0.2	0.2	-0.0	0.2	0.3	-0.1	-0.0	-0.2	-0.0	0.4	0.6	-0.3	-0.3	0.2

Hub : Genes

PPM1N

Models

Trait associations