Best TWAS P=4.64e-09 · Best GWAS P=6.98e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | PQLC3 | 0.22 | 0.12 | enet | 7 | 0.09 | 1.7e-05 | 5.7 | 5.4 | 7.7e-08 | 0.96 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Esophagus Muscularis | PQLC3 | 0.16 | 0.10 | enet | 5 | 0.07 | 4.3e-05 | 5.8 | 5.5 | 4.7e-08 | 0.97 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Nerve Tibial | PQLC3 | 0.29 | 0.20 | lasso | 7 | 0.22 | 2.6e-15 | 5.6 | 5.4 | 5.8e-08 | 0.89 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Ovary | PQLC3 | 0.32 | 0.11 | lasso | 5 | 0.12 | 9.5e-04 | 5.5 | 5.6 | 1.9e-08 | 0.89 | 0.01 | 0.94 | FALSE |
| 5 | GTEx | Skin Not Sun Exposed Suprapubic | PQLC3 | 0.16 | 0.10 | lasso | 5 | 0.05 | 1.4e-03 | 5.6 | 5.8 | 8.5e-09 | 0.94 | 0.02 | 0.98 | FALSE |
| 6 | GTEx | Stomach | PQLC3 | 0.17 | 0.08 | lasso | 3 | 0.04 | 4.0e-03 | 5.8 | 5.9 | 4.6e-09 | 0.99 | 0.01 | 0.99 | TRUE |
| 7 | NTR | Blood | PQLC3 | 0.15 | 0.14 | enet | 14 | 0.15 | 1.8e-45 | 5.8 | 5.6 | 2.6e-08 | 0.96 | 0.00 | 1.00 | FALSE |
| 8 | YFS | Blood | PQLC3 | 0.22 | 0.04 | lasso | 8 | 0.18 | 1.3e-57 | 5.1 | -5.4 | 5.9e-08 | -0.54 | 0.10 | 0.90 | FALSE |