[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr2:8,917,977-10,394,558

Best TWAS P=2.06e-10 · Best GWAS P=1.1e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts IAH1 0.09 0.10 lasso 4 0.07 3.7e-06 -5.2 -5.2 2.0e-07 0.83 0.25 0.73 FALSE
2 GTEx Muscle Skeletal ADAM17 0.07 0.07 enet 5 0.05 4.5e-06 -6.0 -6.4 2.1e-10 0.95 0.00 1.00 TRUE
3 GTEx Muscle Skeletal RP11-400L8.2 0.11 0.11 lasso 7 0.11 7.9e-11 -5.2 5.2 2.2e-07 -0.83 0.24 0.75 FALSE
4 GTEx Nerve Tibial ADAM17 0.10 0.02 enet 8 0.01 3.9e-02 -5.2 5.4 6.8e-08 -0.87 0.04 0.94 FALSE
5 GTEx Testis IAH1 0.30 0.07 lasso 6 0.09 5.8e-05 -5.2 -5.3 9.3e-08 0.81 0.18 0.71 FALSE
6 NTR Blood ADAM17 0.03 0.03 lasso 8 0.03 2.1e-09 -5.2 5.5 4.7e-08 -0.84 0.22 0.78 FALSE
7 ROSMAP Brain Pre-frontal Cortex IAH1 0.08 0.07 lasso 5 0.07 8.8e-09 -5.3 -5.3 9.2e-08 0.79 0.26 0.74 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma ADAM17 0.03 0.02 blup 41 0.03 1.8e-06 -5.1 -5.9 3.6e-09 0.80 0.18 0.80 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IAH1 0.03 0.01 blup 35 0.02 1.7e-03 -5.2 -5.4 6.7e-08 0.77 0.04 0.60 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma ADAM17 0.03 0.01 blup 41 0.02 4.7e-03 -5.2 -5.6 2.2e-08 0.85 0.04 0.64 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors ADAM17 0.10 0.14 lasso 2 0.13 3.2e-05 -5.9 -5.9 3.4e-09 0.97 0.01 0.98 FALSE