[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr12:30,084,002-31,526,510

Best TWAS P=7.69e-12 · Best GWAS P=1.31e-11 conditioned to 0.217

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex IPO8 0.22 0.28 lasso 8 0.29 1.0e-35 -6.5 6.5 5.8e-11 -0.99 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous IPO8 0.13 0.09 lasso 6 0.12 2.7e-10 -6.5 6.4 1.4e-10 -0.92 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum IPO8 0.17 0.08 lasso 2 0.05 9.9e-04 -6.7 6.7 2.7e-11 -0.99 0.01 0.98 FALSE
4 GTEx Artery Tibial IPO8 0.17 0.14 lasso 4 0.14 4.5e-11 -6.6 6.3 2.8e-10 -0.93 0.01 0.99 FALSE
5 GTEx Breast Mammary Tissue IPO8 0.11 0.11 lasso 10 0.08 4.3e-05 -6.5 6.7 2.5e-11 -0.97 0.01 0.98 FALSE
6 GTEx Breast Mammary Tissue (Female) IPO8 0.12 0.10 lasso 3 0.04 2.0e-02 -6.5 6.7 1.8e-11 -0.93 0.02 0.88 FALSE
7 GTEx Cells EBV-transformed lymphocytes IPO8 0.22 0.14 lasso 4 0.14 2.5e-05 4.1 5.9 3.2e-09 -0.82 0.03 0.97 FALSE
8 GTEx Cells Transformed fibroblasts IPO8 0.25 0.22 enet 19 0.26 9.4e-20 -6.7 6.2 4.5e-10 -0.90 0.01 0.99 FALSE
9 GTEx Colon Transverse IPO8 0.11 0.11 lasso 2 0.10 2.4e-05 -6.5 6.6 3.6e-11 -0.98 0.01 0.99 FALSE
10 GTEx Esophagus Mucosa IPO8 0.30 0.14 lasso 6 0.19 1.1e-12 -6.5 5.7 1.5e-08 -0.82 0.01 0.99 FALSE
11 GTEx Esophagus Muscularis IPO8 0.24 0.19 lasso 6 0.18 5.7e-11 -6.7 6.5 9.1e-11 -0.97 0.01 0.99 FALSE
12 GTEx Lung IPO8 0.07 0.06 lasso 5 0.07 7.5e-06 -6.5 6.1 8.6e-10 -0.90 0.02 0.98 FALSE
13 GTEx Skin Sun Exposed Lower leg IPO8 0.23 0.08 lasso 10 0.13 1.1e-10 4.0 5.8 8.7e-09 -0.85 0.03 0.97 FALSE
14 GTEx Whole Blood IPO8 0.09 0.00 lasso 4 0.00 2.9e-01 -6.5 6.1 1.1e-09 -0.95 0.02 0.89 FALSE
15 METSIM Adipose IPO8 0.06 0.04 lasso 6 0.03 9.2e-06 -6.6 6.7 2.8e-11 -0.99 0.01 0.99 FALSE
16 ROSMAP Brain Pre-frontal Cortex IPO8 0.21 0.23 lasso 12 0.22 8.0e-28 -6.5 6.6 3.9e-11 -0.95 0.01 0.99 FALSE
17 The Cancer Genome Atlas Bladder Urothelial Carcinoma IPO8 0.06 0.04 lasso 8 0.03 1.5e-03 -6.6 6.5 1.0e-10 -0.98 0.01 0.96 FALSE
18 The Cancer Genome Atlas Breast Invasive Carcinoma IPO8 0.05 0.03 lasso 3 0.03 1.3e-06 -6.5 6.4 1.7e-10 -0.96 0.01 0.99 FALSE
19 The Cancer Genome Atlas Colon Adenocarcinoma IPO8 0.06 0.06 blup 64 0.05 6.2e-04 -6.5 6.7 1.7e-11 -0.97 0.01 0.97 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma IPO8 0.06 0.02 blup 58 0.02 3.0e-03 -3.4 5.2 2.3e-07 -0.83 0.01 0.89 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IPO8 0.08 0.07 enet 7 0.06 4.9e-07 -6.7 6.5 1.1e-10 -0.98 0.01 0.99 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma IPO8 0.12 0.07 lasso 4 0.07 3.2e-08 -6.5 6.5 5.8e-11 -0.99 0.01 0.99 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma IPO8 0.06 0.04 blup 58 0.04 1.5e-05 -6.8 6.8 7.7e-12 -0.92 0.01 0.99 TRUE
24 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IPO8 0.04 0.03 blup 58 0.03 9.7e-05 -6.5 6.6 3.5e-11 -0.95 0.01 0.98 FALSE
25 The Cancer Genome Atlas Pancreatic Adenocarcinoma IPO8 0.09 0.05 blup 64 0.03 2.9e-02 -6.5 6.6 4.1e-11 -0.98 0.01 0.92 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma IPO8 0.06 0.04 blup 64 0.03 2.1e-04 -6.5 6.0 2.5e-09 -0.88 0.01 0.98 FALSE
27 The Cancer Genome Atlas Soft Tissue Sarcoma IPO8 0.07 0.04 lasso 7 0.02 1.9e-02 -6.5 5.8 6.4e-09 -0.94 0.01 0.96 FALSE
28 The Cancer Genome Atlas Stomach Adenocarcinoma IPO8 0.04 0.04 enet 7 0.02 8.1e-03 -6.5 6.6 4.9e-11 -0.98 0.01 0.94 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma IPO8 0.07 0.06 blup 58 0.07 5.6e-07 -6.7 6.1 1.1e-09 -0.95 0.01 0.99 FALSE