[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr12:25,589,747-28,607,631

Best TWAS P=4.66e-24 · Best GWAS P=6.68e-51 conditioned to 4.08e-18

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	SSPN	0.16	0.06	lasso	7	0.07	1.1e-06	-5.2	6.5	9.6e-11	0.42	0.79	0.13	FALSE
2	GTEx	Adipose Subcutaneous	RP11-283G6.5	0.13	0.04	lasso	7	0.02	5.8e-03	-5.2	5.9	3.3e-09	0.35	0.16	0.55	TRUE
3	GTEx	Brain Putamen basal ganglia	STK38L	0.28	0.08	lasso	7	0.05	2.6e-02	4.8	5.5	3.7e-08	0.00	0.08	0.15	TRUE
4	GTEx	Breast Mammary Tissue	SSPN	0.27	0.00	lasso	9	0.02	4.1e-02	-5.1	5.5	5.1e-08	0.47	0.17	0.43	TRUE
5	GTEx	Breast Mammary Tissue	RP11-283G6.5	0.17	0.02	enet	9	0.02	2.9e-02	-5.1	10.1	4.7e-24	0.68	0.04	0.67	TRUE
6	GTEx	Breast Mammary Tissue (Male)	SSPN	0.23	-0.01	enet	47	0.02	1.3e-01	11.8	7.5	8.2e-14	0.49	0.05	0.29	FALSE
7	GTEx	Breast Mammary Tissue (Male)	RP11-283G6.5	0.04	0.00	enet	16	-0.01	5.1e-01	-5.1	7.5	9.0e-14	0.53	0.05	0.17	TRUE
8	GTEx	Cells Transformed fibroblasts	SSPN	0.14	0.07	enet	15	0.16	3.1e-12	-5.2	6.0	2.2e-09	0.31	1.00	0.00	FALSE
9	GTEx	Cells Transformed fibroblasts	RP11-283G6.5	0.16	0.05	enet	14	0.15	2.2e-11	-5.2	6.0	1.6e-09	0.30	1.00	0.00	TRUE
10	GTEx	Esophagus Mucosa	MRPS35	0.18	0.00	enet	20	0.01	6.6e-02	-5.4	6.0	2.7e-09	-0.05	0.03	0.72	TRUE
11	GTEx	Heart Atrial Appendage	SSPN	0.27	0.00	enet	4	0.01	1.2e-01	-5.2	5.3	1.3e-07	0.31	0.09	0.14	TRUE
12	YFS	Blood	ITPR2	0.27	0.19	lasso	7	0.22	1.9e-69	9.9	-9.7	2.8e-22	-0.65	1.00	0.00	FALSE
13	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SSPN	0.15	0.04	lasso	3	0.07	4.6e-04	-4.5	6.0	1.6e-09	0.51	0.02	0.57	TRUE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	BHLHE41	0.03	0.02	enet	9	0.02	2.8e-03	-5.5	6.0	2.0e-09	0.21	0.05	0.52	TRUE
15	The Cancer Genome Atlas	Thyroid Carcinoma	SSPN	0.08	0.03	lasso	4	0.04	7.5e-05	-7.9	8.0	1.8e-15	0.17	0.24	0.02	TRUE