[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr12:33,480,976-34,826,574

Best TWAS P=9.55e-12 · Best GWAS P=1.88e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ALG10 0.11 0.06 enet 19 0.06 4.1e-08 -6.1 5.7 9.9e-09 -0.60 0.20 0.80 FALSE
2 GTEx Adipose Visceral Omentum ALG10 0.06 0.04 lasso 6 0.02 3.5e-02 -6.4 6.8 9.6e-12 -0.95 0.08 0.87 TRUE
3 GTEx Brain Nucleus accumbens basal ganglia ALG10 0.25 0.10 lasso 4 0.21 2.1e-06 3.7 6.1 8.9e-10 -0.69 0.17 0.32 FALSE
4 GTEx Cells Transformed fibroblasts ALG10 0.05 0.04 lasso 2 0.04 5.6e-04 -6.0 6.2 5.8e-10 -0.84 0.39 0.57 FALSE
5 GTEx Nerve Tibial ALG10 0.08 0.04 lasso 8 0.04 9.7e-04 -6.0 6.3 3.0e-10 -0.78 0.11 0.81 FALSE
6 METSIM Adipose ALG10 0.05 0.04 blup 224 0.05 4.2e-08 -6.7 6.5 9.3e-11 -0.85 0.07 0.93 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma ALG10 0.02 0.02 enet 3 0.02 8.0e-05 -6.0 5.7 1.6e-08 -0.74 0.01 0.98 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ALG10 0.07 0.07 blup 26 0.07 1.1e-08 -6.0 6.2 4.8e-10 -0.82 0.01 0.99 FALSE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ALG10 0.11 0.06 enet 8 0.08 4.1e-05 -5.8 6.1 1.3e-09 -0.79 0.01 0.97 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma ALG10 0.05 0.05 blup 26 0.06 2.3e-07 -5.8 5.6 2.1e-08 -0.67 0.01 0.99 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors ALG10 0.12 -0.01 blup 26 0.02 8.9e-02 -6.0 5.4 7.6e-08 -0.76 0.00 0.74 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma ALG10 0.13 0.04 lasso 1 0.04 1.4e-04 -5.8 5.8 6.2e-09 -0.81 0.01 0.98 FALSE