[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr12:53,353,508-55,370,164

Best TWAS P=8.09e-25 · Best GWAS P=7.82e-45 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Uterus ATP5G2 0.47 0.35 enet 34 0.38 8.5e-09 -2.95 -6.3 3.2e-10 -0.34 0.49 0.18 TRUE
2 GTEx Whole Blood HNRNPA1 0.10 0.00 enet 24 0.00 1.1e-01 -0.55 7.5 7.5e-14 0.28 0.06 0.04 TRUE
3 The Cancer Genome Atlas Breast Invasive Carcinoma FLJ12825 0.32 0.29 lasso 5 0.32 1.7e-67 6.22 6.3 2.6e-10 0.09 1.00 0.00 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma HOTAIR 0.02 0.03 lasso 5 0.03 3.2e-06 4.40 5.5 3.8e-08 0.58 0.74 0.20 TRUE
5 The Cancer Genome Atlas Breast Invasive Carcinoma LOC100240734 0.05 0.05 enet 9 0.05 8.4e-11 -6.08 -6.1 1.1e-09 -0.08 0.01 0.99 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FLJ12825 0.35 0.21 lasso 5 0.26 5.5e-13 6.22 5.9 3.0e-09 0.08 1.00 0.00 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma FLJ12825 0.26 0.13 lasso 5 0.19 2.9e-11 6.34 5.6 2.5e-08 0.07 0.99 0.00 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma SMUG1 0.05 0.03 lasso 3 0.05 7.2e-04 -2.57 -5.4 7.8e-08 -0.06 0.01 0.85 FALSE
9 The Cancer Genome Atlas Esophageal Carcinoma FLJ12825 0.12 0.05 blup 59 0.02 6.9e-02 -3.76 6.4 1.4e-10 0.10 0.03 0.13 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FLJ12825 0.35 0.27 lasso 5 0.29 7.4e-33 6.22 5.2 1.8e-07 0.08 1.00 0.00 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FLJ12825 0.54 0.56 enet 12 0.57 2.5e-78 6.22 6.1 9.9e-10 0.10 1.00 0.00 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HOTAIR 0.08 0.13 enet 12 0.13 1.1e-14 4.96 6.8 1.1e-11 0.60 1.00 0.00 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HOXC6 0.03 0.02 blup 50 0.03 3.9e-04 7.79 -7.4 1.3e-13 0.10 0.04 0.80 TRUE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HOXC8 0.03 0.05 enet 5 0.04 2.4e-05 7.79 -8.7 4.3e-18 0.03 0.02 0.95 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC100240734 0.11 0.10 lasso 4 0.09 4.2e-10 -6.08 -6.1 1.2e-09 -0.08 0.01 0.99 TRUE
16 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FLJ12825 0.52 0.36 lasso 4 0.37 2.1e-22 6.22 6.6 4.3e-11 0.10 1.00 0.00 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma LOC400043 0.05 0.05 lasso 3 0.04 4.1e-05 5.11 5.8 7.2e-09 0.06 0.09 0.85 FALSE
18 The Cancer Genome Atlas Pancreatic Adenocarcinoma FLJ12825 0.25 0.09 lasso 4 0.12 1.6e-05 -6.17 5.8 8.2e-09 0.08 0.44 0.04 FALSE
19 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma FLJ12825 0.35 0.23 lasso 2 0.21 8.8e-09 6.22 6.7 2.0e-11 0.10 0.97 0.00 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma HOTAIR 0.10 0.12 lasso 3 0.11 1.8e-11 4.40 5.5 3.4e-08 0.45 1.00 0.00 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma HOXC11 0.09 0.04 lasso 2 0.03 9.3e-04 -9.99 10.3 8.1e-25 -0.09 0.27 0.05 TRUE
22 The Cancer Genome Atlas Soft Tissue Sarcoma FLJ12825 0.19 0.06 enet 7 0.11 3.9e-07 6.09 7.6 3.4e-14 0.11 0.98 0.00 TRUE
23 The Cancer Genome Atlas Skin Cutaneous Melanoma HOXC10 0.33 0.02 blup 56 0.06 8.2e-03 -6.65 -7.5 7.7e-14 -0.38 0.01 0.06 FALSE
24 The Cancer Genome Atlas Stomach Adenocarcinoma FLJ12825 0.18 0.11 lasso 3 0.16 1.4e-11 -2.57 5.2 2.3e-07 0.07 1.00 0.00 TRUE
25 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma FLJ12825 0.15 0.02 lasso 5 0.06 8.9e-03 7.78 8.8 1.5e-18 -0.04 0.02 0.28 TRUE